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Cited by 48HIV/AIDS Research and InterventionsHealth disparities and outcomesHIV Research and Treatment

The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.

Social relationships and immune processes in HIV seropositive gay and bisexual men

Miller, Gregory E., Kemeny, Margaret E., Taylor, Shelley E., Cole, Steve W., Visscher, Barbara R.·1997·Annals of Behavioral Medicine
DOI 10.1007/bf02883331
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Abstract

This three-year longitudinal study assessed the association between social relationships and human immunodeficiency virus (HIV) progression in individuals at risk for morbidity and mortality due to acquired immune deficiency syndrome (AIDS). Two-hundred five HIV seropositive men without AIDS completed measures of social integration and loneliness at baseline. Blood samples used to assess CD4 T-lymphocyte levels were collected at baseline and at six-month intervals for a three-year follow-up period. Contrary to expectation, lower levels of baseline loneliness predicted more rapid declines in CD4 levels over the follow-up period. This association was independent of baseline CD4 values, negative affect, and health practices. A series of mediational analyses revealed that sexual behavior, medication use, bereavement, coping, and a number of other variables were not mechanisms through which loneliness affected the immune system. Loneliness was not associated with time to AIDS diagnosis or time to AIDS-related mortality. These findings are consistent with the emerging view that social relationships can have deleterious, as well as protective, influences on health outcomes.

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Crossref · 10.1007/bf02883331

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  • Among HIV-positive men without AIDS, no association was observed between loneliness and time to AIDS diagnosis or AIDS-related mortality.

    “These data suggest that loneliness protects against disease progression, but no association was observed between loneliness and time to AIDS diagnosis or AIDS-related mortality [84].”

    From Loneliness matters: a theoretical and empirical review of consequences and mechanisms (2010) · cites this paper as [84]

  • Among HIV-positive men without AIDS, loneliness predicts a slower rate of decline in levels of CD4 T-lymphocytes over a 3-year period.

    “However, in the latter study, loneliness predicted a slower rate of decline in levels of CD4 T-lymphocytes over a 3-year period [84].”

    From Loneliness matters: a theoretical and empirical review of consequences and mechanisms (2010) · cites this paper as [84]

  • Among HIV-positive men without AIDS, loneliness is not associated with CD4 count in another study.

    “Among HIV-positive men without AIDS, loneliness was associated with a lower count of CD4 T-lymphocytes in one study [83] but was not associated with the CD4 count in another study [84].”

    From Loneliness matters: a theoretical and empirical review of consequences and mechanisms (2010) · cites this paper as [84]

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Metadata

Authors
Miller, G. E., Kemeny, M. E., Taylor, S. E., Cole, S. W., & Visscher, B. R.
Affiliations
University of California, Los Angeles (US)
Corresponding author
Miller, Gregory E.
ORCID
Venue
Annals of Behavioral Medicine
Publisher
Oxford University Press (OUP)
Published
1997-06
Volume
19
Issue
2
Pages
139-151
ISSN
  • 0742-5554 (ISSN-L)
  • 0883-6612
  • 1532-4796
DOI
10.1007/bf02883331
OpenAlex
W2007468780
Cited by
48
References
1
Citations by year
2021: 1 · 2018: 1 · 2017: 1 · 2016: 1 · 2015: 1 · 2014: 2 · 2013: 2 · 2012: 5
FWCI
2.23
Type
journal article
Language
en
Open access
closed
Locations
  • Annals of Behavioral Medicine (publishedVersion)
  • PubMed (publishedVersion)
Funders
  • U.S. Public Health Service (N01-A1-72631)
  • National Institute of Mental Health (R01MH042918, T32MH015750)
Topics
  • Health Sciences › Medicine › Infectious Diseases › HIV/AIDS Research and Interventions
  • Social Sciences › Health › Health disparities and outcomes
  • Life Sciences › Immunology and Microbiology › Virology › HIV Research and Treatment
Keywords
loneliness, interpersonal relationships, HIV seropositivity, immune function, AIDS progression, gay and bisexual men, social integration, AIDS mortality, mediation analysis, coping, bereavement, sexual behavior
MeSH terms
Acquired Immunodeficiency Syndrome, Bisexuality, Follow-Up Studies, HIV Seropositivity, Humans, Interpersonal Relations, Life Change Events, Loneliness, Male, Psychoneuroimmunology, Social Adjustment, Social Support, Los Angeles, Cohort Studies, Homosexuality, Male, CD4 Lymphocyte Count

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