Osteoarthritis and osteoporosis: Clinical and research evidence of inverse relationship

Mutation of the mouse klotho gene leads to a syndrome resembling ageing

Kuro-o, M., Matsumura, Y., Aizawa, H., Kawaguchi, H., Suga, T., Utsugi, T., Ohyama, Y., Kurabayashi, M., Kaname, T., Kume, E., et al. (1997) · Nature · doi:10.1038/36285 · Cited by 3,837

OPGL is a key regulator of osteoclastogenesis, lymphocyte development and lymph node organogenesis.

Kong, Y.-Y., Yoshida, H., Sarosi, I., Tan, H.-L., Timms, E., Capparelli, C., Morony, S., Oliveira-dos-Santos, A. J., Van, G., Itie, A., et al. (1999) · Nature · doi:10.1038/16852 · Cited by 3,351

Prediction of bone density from vitamin D receptor alleles

Morrison, N. A., Qi, J. C., Tokita, A., Kelly, P. J., Crofts, L., Nguyen, T. V., Sambrook, P. N., & Eisman, J. A. (1994) · Nature · doi:10.1038/367284a0 · Cited by 1,919

The Roles of Osteoprotegerin and Osteoprotegerin Ligand in the Paracrine Regulation of Bone Resorption

Hofbauer, L. C., Khosla, S., Dunstan, C. R., Lacey, D. L., Boyle, W. J., & Riggs, B. L. (2000) · Journal of Bone and Mineral Research · doi:10.1359/jbmr.2000.15.1.2 · Cited by 1,173

Role of Subchondral Bone in the Initiation and Progression of Cartilage Damage

RADIN, E. L., & ROSE, R. M. (1986) · Clinical Orthopaedics and Related Research · doi:10.1097/00003086-198612000-00005 · Cited by 1,075

Guidelines for the medical management of osteoarthritis

Hochberg, M. C., Altman, R. D., Brandt, K. D., Clark, B. M., Dieppe, P. A., Griffin, M. R., Moskowitz, R. W., & Schnitzer, T. J. (1995) · Arthritis & Rheumatism · doi:10.1002/art.1780381103 · Cited by 968

The Mechanical Adaptations of Bones

Currey, J. D. (1984) · Princeton University Press eBooks · doi:10.1515/9781400853724 · Cited by 896

Consensus Development Conference: A Cross-Cultural Study

Larsen, J. K., & Rogers, E. M. (1984) · Knowledge · doi:10.1177/107554708400500406 · Cited by 751

Briefe an die Redaktion

Kopera, H., & Ziegler, R. (1989) · Klinische Wochenschrift · doi:10.1007/bf01719785 · Cited by 749

Consensus development conference: prophylaxis and treatment of osteoporosis.

(1987) · BMJ · doi:10.1136/bmj.295.6603.914 · Cited by 727

Bone Compressive Strength: The Influence of Density and Strain Rate

Carter, D. R., & Hayes, W. C. (1976) · Science · doi:10.1126/science.996549 · Cited by 709

Simple measurement of femoral geometry predicts hip fracture: The study of osteoporotic fractures

Faulkner, K. G., Cummings, S. R., Black, D., Palermo, L., Glüer, C.-C., & Genant, H. K. (1993) · Journal of Bone and Mineral Research · doi:10.1002/jbmr.5650081008 · Cited by 706

Suppressed Bone Turnover by Bisphosphonates Increases Microdamage Accumulation and Reduces Some Biomechanical Properties in Dog Rib

Mashiba, T., Hirano, T., Turner, C. H., Forwood, M. R., Johnston, C. C., & Burr, D. B. (2000) · Journal of Bone and Mineral Research · doi:10.1359/jbmr.2000.15.4.613 · Cited by 688

Collagen cross-links in mineralizing tissues: A review of their chemistry, function, and clinical relevance

Knott, L., & Bailey, A. J. (1998) · Bone · doi:10.1016/s8756-3282(97)00279-2 · Cited by 641

Consensus development conference: prophylaxis and treatment of osteoporosis

(1991) · The American Journal of Medicine · doi:10.1016/0002-9343(91)90512-v · Cited by 632

BONE MASS IN POSTMENOPAUSAL WOMEN AFTER WITHDRAWAL OF OESTROGEN/GESTAGEN REPLACEMENT THERAPY

Christiansen, C., Sanvig Christensen, M., & Transbøl, I. (1981) · The Lancet · doi:10.1016/s0140-6736(81)91848-1 · Cited by 593

Expression of a Truncated, Kinase-Defective TGF-β Type II Receptor in Mouse Skeletal Tissue Promotes Terminal Chondrocyte Differentiation and Osteoarthritis

Serra, R., Johnson, M., Filvaroff, E. H., LaBorde, J., Sheehan, D. M., Derynck, R., & Moses, H. L. (1997) · The Journal of Cell Biology · doi:10.1083/jcb.139.2.541 · Cited by 477

Composition and Mechanical Properties of Cancellous Bone from the Femoral Head of Patients with Osteoporosis or Osteoarthritis

Li, B., & Dr. Aspden, R. M. (1997) · Journal of Bone and Mineral Research · doi:10.1359/jbmr.1997.12.4.641 · Cited by 457

Type x collagen synthesis in human osteoarthritic cartilage. indication of chondrocyte hypertrophy

Von Der Mark, K., Kirsch, T., Nerlich, A., Kuss, A., Weseloh, G., Glückert, K., & Stöss, H. (1992) · Arthritis & Rheumatism · doi:10.1002/art.1780350715 · Cited by 449

Radiographic osteoarthritis of the hip and bone mineral density

Nevitt, M. C., Lane, N. E., Scott, J. C., Hochberg, M. C., Pressman, A. R., Genant, H. K., & Cummings, S. R. (1995) · Arthritis & Rheumatism · doi:10.1002/art.1780380706 · Cited by 362

The relationship between osteoarthritis and osteoporosis in the general population: the Chingford Study.

Hart, D. J., Mootoosamy, I., Doyle, D. V., & Spector, T. D. (1994) · Annals of the Rheumatic Diseases · doi:10.1136/ard.53.3.158 · Cited by 315

Bone density, osteoarthrosis of the hip, and fracture of the upper end of the femur.

Foss, M. V., & Byers, P. D. (1972) · Annals of the Rheumatic Diseases · doi:10.1136/ard.31.4.259 · Cited by 303

Subchondral bone in osteoarthritis

Grynpas, M. D., Alpert, B., Katz, I., Lieberman, I., & Pritzker, K. P. H. (1991) · Calcified Tissue International · doi:10.1007/bf02555898 · Cited by 294

Assessment of the strength of proximal femur in vitro: Relationship to femoral bone mineral density and femoral geometry

Cheng, X. G., Lowet, G., Boonen, S., Nicholson, P. H. F., Brys, P., Nijs, J., & Dequeker, J. (1997) · Bone · doi:10.1016/s8756-3282(96)00383-3 · Cited by 283

Association of radiographically evident osteoarthritis with higher bone mineral density and increased bone loss with age. The rotterdam study

Burger, H., van Daele, P. L. A., Odding, E., Valkenburg, H. A., Hofman, A., Grobbee, D. E., Schütte, H. E., Birkenhäger, J. C., & Pols, H. A. P. (1996) · Arthritis & Rheumatism · doi:10.1002/art.1780390111 · Cited by 268

Dual role for the latent transforming growth factor-beta binding protein in storage of latent TGF-beta in the extracellular matrix and as a structural matrix protein.

Dallas, S. L., Miyazono, K., Skerry, T. M., Mundy, G. R., & Bonewald, L. F. (1995) · The Journal of cell biology · doi:10.1083/jcb.131.2.539 · Cited by 267

Bone mineral density and knee osteoarthritis in elderly men and women. the framingham study

Hannan, M. T., Anderson, J. J., Zhang, Y., Levy, D., & Felson, D. T. (1993) · Arthritis & Rheumatism · doi:10.1002/art.1780361205 · Cited by 265

KNEE PAIN AND DISABILITY IN THE COMMUNITY

McALINDON, T. E., COOPER, C., KIRWAN, J. R., & DIEPPE, P. A. (1992) · Rheumatology · doi:10.1093/rheumatology/31.3.189 · Cited by 243

Type II autosomal dominant osteopetrosis (Albers-Schönberg disease): clinical and radiological manifestations in 42 patients

Bénichou, O. D., Laredo, J. D., & de Vernejoul, M. C. (2000) · Bone · doi:10.1016/s8756-3282(99)00244-6 · Cited by 236

The Influence of Osteophytes and Aortic Calcification on Spinal Mineral Density in Postmenopausal Women*

REID, I. R., EVANS, M. C., AMES, R., & WATTIE, D. J. (1991) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem-72-6-1372 · Cited by 231

Overweight, gender and knee osteoarthritis.

Manninen, P., Riihimäki, H., Heliövaara, M., & Mäkelä, P. (1996) · PubMed · Cited by 228

Bone mineral density and risk factors for osteoporosis—A population-based study of 1600 perimenopausal women

Kröger, H., Tuppurainen, M., Honkanen, R., Alhava, E., & Saarikoski, S. (1994) · Calcified Tissue International · doi:10.1007/bf00310160 · Cited by 228

Effect of spinal osteophytosis on bone mineral density measurements in vertebral osteoporosis.

Masud, T., Langley, S., Wiltshire, P., Doyle, D. V., & Spector, T. D. (1993) · BMJ · doi:10.1136/bmj.307.6897.172 · Cited by 215

Epidemiology of risk factors for osteoarthritis: systemic factors

Sowers, M. (2001) · Current Opinion in Rheumatology · doi:10.1097/00002281-200109000-00018 · Cited by 215

Urinary hydroxy-pyridinium crosslinks provide indices of cartilage and bone involvement in arthritic diseases.

Seibel, M. J., Duncan, A., & Robins, S. P. (1989) · PubMed · Cited by 213

Osteoblast-like cells from human subchondral osteoarthritic bone demonstrate an altered phenotype in vitro: Possible role in subchondral bone sclerosis

Hilal, G., Martel-Pelletier, J., Pelletier, J.-P., Ranger, P., & Lajeunesse, D. (1998) · Arthritis & Rheumatism · doi:10.1002/1529-0131(199805)41:5<891::aid-art17>3.0.co;2-x · Cited by 211

Axial Bone Mass in Older Women

Orwoll, E. S., Bauer, D. C., Vogt, T. M., & Fox, K. M. (1996) · Annals of Internal Medicine · doi:10.7326/0003-4819-124-2-199601150-00001 · Cited by 210

Osteoarthritis and risk of falls, rates of bone loss, and osteoporotic fractures

Arden, N., Nevitt, M. C., Lane, N. E., Gore, L. R., Hochberg, M. C., Scott, J. C., Pressman, A. R., & Cummings, S. R. (1999) · Arthritis & Rheumatism · doi:10.1002/1529-0131(199907)42:7<1378::aid-anr11>3.0.co;2-i · Cited by 202

Differentiation and Cell Surface Expression of Transforming Growth Factor-β Receptors Are Regulated by Interaction with Matrix Collagen in Murine Osteoblastic Cells

Takeuchi, Y., Nakayama, K., & Matsumoto, T. (1996) · Journal of Biological Chemistry · doi:10.1074/jbc.271.7.3938 · Cited by 201

The importance of subchondral bone in osteoarthrosis

Burr, D. B. (1998) · Current Opinion in Rheumatology · doi:10.1097/00002281-199805000-00017 · Cited by 196

Osteoarthritis in cynomolgus macaques III: Effects of age, gender, and subchondral bone thickness on the severity of disease

Carlson, C. S., Loeser, R. F., Purser, C. B., Gardin, J. F., & Jerome, C. P. (1996) · Journal of Bone and Mineral Research · doi:10.1002/jbmr.5650110904 · Cited by 195

Alteration of cartilage metabolism by cells from osteoarthritic bone

Westacott, C. I., Webb, G. R., Warnock, M. G., Sims, J. V., & Elson, C. J. (1997) · Arthritis & Rheumatism · doi:10.1002/1529-0131(199707)40:7<1282::aid-art13>3.0.co;2-e · Cited by 194

Generalized osteoarthritis associated with increased insulin‐like growth factor types i and ii and transforming growth factor β in cortical bone from the iliac crest. possible mechanism of increased bone density and protection against osteoporosis

Dequeker, J., Mohan, S., Finkelman, R. D., Aerssens, J., & Baylink, D. J. (1993) · Arthritis & Rheumatism · doi:10.1002/art.1780361209 · Cited by 190

Persistence of monosodium urate crystals and low‐grade inflammation in the synovial fluid of patients with untreated gout

Pascual, E. (1991) · Arthritis & Rheumatism · doi:10.1002/art.1780340203 · Cited by 180

Guidelines for the medical management of osteoarthritis, Part I. Osteoarthritis of the hip

Mc, H. (1995) · Medical Entomology and Zoology · Cited by 180

Functions of mammalian Smad genes as revealed by targeted gene disruption in mice

Weinstein, M., Yang, X., & Deng, C.-X. (2000) · Cytokine & Growth Factor Reviews · doi:10.1016/s1359-6101(99)00028-3 · Cited by 172

The associations of bone mineral density and bone turnover markers with osteoarthritis of the hand and knee in pre- and perimenopausal women

Sowers, M., Lachance, L., Jamadar, D., Hochberg, M. C., Hollis, B., Crutchfield, M., & Jannausch, M. L. (1999) · Arthritis & Rheumatism · doi:10.1002/1529-0131(199904)42:3<483::aid-anr13>3.0.co;2-o · Cited by 167

Osteoarthritis in cynomolgus macaques: A primate model of naturally occurring disease

Carlson, C. S., Loeser, R. F., Jayo, M. J., Weaver, D. S., Adams, M. R., & Jerome, C. P. (1994) · Journal of Orthopaedic Research® · doi:10.1002/jor.1100120305 · Cited by 166

Osteoporosis and osteoarthritis (osteoarthrosis). Anthropometric distinctions

Dequeker, J. (1983) · JAMA · doi:10.1001/jama.249.11.1448 · Cited by 158

Influence of degenerative joint disease on spinal bone mineral measurements in postmenopausal women

Yu, W., Gl�er, C. C., Fuerst, T., Grampp, S., Li, J., Lu, Y., & Genant, H. K. (1995) · Calcified Tissue International · doi:10.1007/bf00310253 · Cited by 154

Osteoarthritis, bone density, postural stability, and osteoporotic fractures: a population based study.

Jones, G., Nguyen, T. V., Sambrook, P. N., Lord, S. R., Kelly, P. J., & Eisman, J. A. (1995) · PubMed · Cited by 144

Epidemiologic Studies of Osteoporosis in Women of Puerto Rico and Southeastern Michigan With Special Reference to Age, Race, National Origin and to Other Related or Associated Findings

Smith, R. W., & RIZEK, J. (1966) · Clinical Orthopaedics and Related Research · doi:10.1097/00003086-196600450-00005 · Cited by 141

Osteoarthritis protects against femoral neck fracture: The MEDOS study experience

Dequeker, J., Johnell, O., Dilşen, G., Gennari, C., Vaz, A. A. L., Lyritis, G. P., Mazzuoli, G., Miravet, L., Passeri, M., Pérez‐Cano, R., et al. (1993) · Bone · doi:10.1016/8756-3282(93)90350-j · Cited by 136

Fracture Site-Specific Deficits in Bone Size and Volumetric Density in Men with Spine or Hip Fractures

Seeman, E., Duan, Y., Fong, C., & Edmonds, J. (2001) · Journal of Bone and Mineral Research · doi:10.1359/jbmr.2001.16.1.120 · Cited by 133

Do Subchondral Bone Changes Exacerbate or Precede Articular Cartilage Destruction in Osteoarthritis of the Elderly?

Bailey, A. J., & Mansell, J. P. (2009) · Gerontology · doi:10.1159/000213866 · Cited by 123

The association between osteoarthritis and osteoporotic fracture: the Chingford Study

Arden, N. K., Griffiths, G. O., Hart, D. J., Doyle, D. V., & Spector, T. D. (1996) · British journal of rheumatology · doi:10.1093/rheumatology/35.12.1299 · Cited by 120

The Relationship between Osteoporosis and Osteoarthritis

Dequeker, J. (1985) · Clinics in Rheumatic Diseases · doi:10.1016/s0307-742x(21)00542-7 · Cited by 120

Bone as a Tissue

Compere, C. L. (1960) · JAMA · doi:10.1001/jama.1960.03020200089030 · Cited by 116

Osteoarthritis of the hip: the patient behind the disease.

Solomon, L. P., Schnitzler, C. M., & Browett, J. (1982) · Annals of the Rheumatic Diseases · doi:10.1136/ard.41.2.118 · Cited by 116

Biochemical evidence for altered subchondral bone collagen metabolism in osteoarthritis of the hip

Mansell, J. P., Tarlton, J. F., & Bailey, A. J. (1997) · Rheumatology · doi:10.1093/rheumatology/36.1.16 · Cited by 116

Osteopetrosis. A morphological study of twenty-one cases.

Milgram, J. W., & Jasty, M. (1982) · Journal of Bone and Joint Surgery · doi:10.2106/00004623-198264060-00016 · Cited by 115

INVERSE RELATIONSHIP OSTEOARTHRITIS—OSTEOPOROSIS: WHAT IS THE EVIDENCE? WHAT ARE THE CONSEQUENCES?

Dequeker, J., Boonen, S., Aerssens, J., & Westhovens, R. (1996) · Lara D. Veeken · doi:10.1093/rheumatology/35.9.813 · Cited by 111

Bone mineral density in osteoarthritis

Stewart, A., & Black, A. J. (2000) · Current Opinion in Rheumatology · doi:10.1097/00002281-200009000-00021 · Cited by 111

Association of klotho gene polymorphism with bone density and spondylosis of the lumbar spine in postmenopausal women

Ogata, N., Matsumura, Y., Shiraki, M., Kawano, K., Koshizuka, Y., Hosoi, T., Nakamura, K., Kuro‐o, M., & Kawaguchi, H. (2002) · Bone · doi:10.1016/s8756-3282(02)00786-x · Cited by 108

Periarticular osteoporosis in osteoarthritis of the knee.

Karvonen, R. L., Miller, P., Nelson, D. A., Granda, J. L., & Fernández-Madrid, F. (1998) · PubMed · Cited by 107

Aging of the thoracic spine: Distinction between wedging in osteoarthritis and fracture in osteoporosis—A cross-sectional and longitudinal study

Osman, A. A.-H., Bassiouni, H., Koutri, R., Nijs, J., Geusens, P., & Dequeker, J. (1994) · Bone · doi:10.1016/8756-3282(94)90822-2 · Cited by 104

Measurement of femoral geometry in type I and type II osteoporosis: Differences in hip axis length consistent with heterogeneity in the pathogenesis of osteoporotic fractures

Boonen, S., Koutri, R., Dequeker, J., Aerssens, J., Lowet, G., Nijs, J., Verbeke, G. N., Lesaffre, E. M. E. H., & Geusens, P. (1995) · Journal of Bone and Mineral Research · doi:10.1002/jbmr.5650101210 · Cited by 102

Bone Mass in Osteoarthrosis, Measured in Vivo by Photon Absorption

Roh, Y.-H., Dequeker, J., & MULIER, J. C. (1974) · Journal of Bone and Joint Surgery · doi:10.2106/00004623-197456030-00016 · Cited by 102

Mineral density quantitation of the human cortical iliac crest by backscattered electron image analysis: Variations with age, sex, and degree of osteoarthritis

BOYDE, A., Jones, S. J., Aerssens, J., & Dequeker, J. (1995) · Bone · doi:10.1016/8756-3282(95)00119-x · Cited by 90

Fractal Properties of Subchondral Cancellous Bone in Severe Osteoarthritis of the Hip

Fazzalari, N. L., & Parkinson, I. H. (1997) · Journal of Bone and Mineral Research · doi:10.1359/jbmr.1997.12.4.632 · Cited by 87

Bone density and bone turnover in patients with osteoarthritis and osteoporosis.

Stewart, A. D., Black, A. J., Robins, S. P., & Reid, D. M. (1999) · PubMed · Cited by 85

Determinants of Bone Mineral Density in Older Men

Orwoll, E. S., Bevan, L., & Phipps, K. R. (2000) · Osteoporosis International · doi:10.1007/s001980070039 · Cited by 82

The relationship between osteoarthritis of the hands, bone mineral density, and osteoporotic fractures in elderly women

Marcelli, C., Favier, F., Kotzki, P. O., Ferrazzi, V., Picot, M., & Simon, L. (1995) · Osteoporosis International · doi:10.1007/bf01622261 · Cited by 75

Relation between insulin-like growth factor-I concentrations, osteoarthritis, bone density, and fractures in the general population: the Chingford study.

Lloyd, M. E., Hart, D. J., Nandra, D., McAlindon, T. E., Wheeler, M., Doyle, D., & Spector, T. D. (1996) · Annals of the Rheumatic Diseases · doi:10.1136/ard.55.12.870 · Cited by 71

Growth Factor Expression in the Osteophytes of the Human Femoral Head in Osteoarthritis

Uchino, M., Izumi, T., Tominaga, T., Wakita, R., Minehara, H., Sekiguchi, M., & Itoman, M. (2000) · Clinical Orthopaedics and Related Research · doi:10.1097/00003086-200008000-00017 · Cited by 68

Physical and histomorphological characteristics of iliac crest bone differ according to the grade of osteoarthritis at the hand

Gevers, G., Dequeker, J., Geusens, P., Behets, C., & Dhem, A. (1989) · Bone · doi:10.1016/8756-3282(89)90050-1 · Cited by 67

Bone Mass in Primary Coxarthrosis

Carlsson, Å., Nilsson, B. E., & Westlin, N. E. (1979) · Acta Orthopaedica Scandinavica · doi:10.3109/17453677908989755 · Cited by 66

Bone mineral density and bone turnover in spinal osteoarthrosis.

Peel, N. F. A., Barrington, N. A., Blumsohn, A., Colwell, A., Hannon, R. A., & Eastell, R. (1995) · Annals of the Rheumatic Diseases · doi:10.1136/ard.54.11.867 · Cited by 65

Growth promoting peptides in osteoarthritis: insulin, insulin-like growth factor-1, growth hormone.

Dequeker, J., Coppens, M., & Geusens, P. (1990) · PubMed · Cited by 64

Abnormal regulation of urokinase plasminogen activator by insulin-like growth factor 1 in human osteoarthritic subchondral osteoblasts

Hilal, G., Martel‐Pelletier, J., Pelletier, J., Duval, N., & Lajeunesse, D. (1999) · Arthritis & Rheumatism · doi:10.1002/1529-0131(199910)42:10<2112::aid-anr11>3.0.co;2-n · Cited by 62

Osteoarthrosis Retards the Development of Osteoarthrosis

VERSTRAETEN, A., Ermen, H. V., HAGHEBAERT, G., Nijs, J., Geusens, P., & Dequeker, J. (1991) · Clinical Orthopaedics and Related Research · doi:10.1097/00003086-199103000-00018 · Cited by 62

Bone mineral density and clinical hand osteoarthritis in elderly men and women: the Rancho Bernardo study.

Schneider, D. L., Barrett-Connor, E. L., Morton, D. J., & Weisman, M. H. (2002) · PubMed · Cited by 59

INSULIN-LIKE GROWTH FACTOR-1: A PROGNOSTIC FACTOR OF KNEE OSTEOARTHRITIS

Schouten, J., Ouweland, F. A. V. D., Valkenburg, H. A., & Lamberts, S. W. J. (1993) · Lara D. Veeken · doi:10.1093/rheumatology/32.4.274 · Cited by 57

Early cell adhesion events differ between osteoporotic and non‐osteoporotic osteoblasts

Perinpanayagam, H., Zaharias, R. S., Stanford, C. M., Brand, R. A., Keller, J. C., & Schneider, G. B. (2001) · Journal of Orthopaedic Research® · doi:10.1016/s0736-0266(01)00045-6 · Cited by 55

Serum levels of insulin‐like growth factor 1 in subjects with osteoarthritis of the knee. Data from the baltimore longitudinal study of aging

Hochberg, M. C., Lethbridge‐Çejku, M., Scott, W. W., Reichle, R., Plato, C. C., & Tobin, J. D. (1994) · Arthritis & Rheumatism · doi:10.1002/art.1780370811 · Cited by 55

Bone density in generalized osteoarthritis.

PRICE, T. R., Hesp, R., & Mitchell, R. (1987) · PubMed · Cited by 55

Histomorphometric changes in the trabecular structure of a selected stress region in the femur in patients with osteoarthritis and fracture of the femoral neck

Fazzalari, N. L., Darracott, J., & Vernon-Roberts, B. (1985) · Bone · doi:10.1016/8756-3282(85)90044-4 · Cited by 50

Appendicular bone mass and osteoarthritis of the hands in women: data from the Baltimore Longitudinal Study of Aging.

Hochberg, M. C., Lethbridge‐Çejku, M., Scott, W. W., Plato, C. C., & Tobin, J. D. (1994) · PubMed · Cited by 48

The relationship between vertebral body deformity and disc degeneration in lumbar spine of the senile

Dai, L. (1998) · European Spine Journal · doi:10.1007/s005860050025 · Cited by 47

Bone mineral distribution of the proximal tibia in gonarthrosis assessed in vivo by photon absorption

Madsen, O. R., Schaadt, O., Bliddal, H., Egsmose, C., & Sylvest, J. (1994) · Osteoarthritis and Cartilage · doi:10.1016/s1063-4584(05)80064-0 · Cited by 43

Bone Mineral Density and Bone Turnover in Patients with Knee Osteoarthritis Compared with Generalized Osteoarthritis

Naitou, K., KUSHIDA, K., Takahashi, M., Ohishi, T., & Inoue, T. M. N. (2000) · Calcified Tissue International · doi:10.1007/s002230010068 · Cited by 43

Altered bone mineral metabolism in patients with osteoarthritis

Miedany, Y. M. E., Mehanna, A. N., & Baddini, M. E. (2000) · Joint Bone Spine · doi:10.1016/s1297-319x(00)00218-9 · Cited by 42

Prevalence and Impact of Arthritis Among Women—United States, 1989-1991

(1995) · JAMA · doi:10.1001/jama.1995.03520470028012 · Cited by 38

Alterations of the mineralization profile and osteocalcin concentrations in osteoarthritic cortical iliac crest bone

Raymaekers, G., Aerssens, J., den Eynde, R. V., et al. (1992) · Calcified Tissue International · doi:10.1007/bf00334486 · Cited by 36

Short-term course of 1,25(OH)2D3 stimulates osteoblasts but not osteoclasts in osteoporosis and osteoarthritis

Geusens, P., Vanderschueren, D., Verstraeten, A., Dequeker, J., Devos, P., & Bouillon, R. (1991) · Calcified Tissue International · doi:10.1007/bf02556112 · Cited by 36

Genetic markers of osteoarticular disorders: facts and hopes.

Brandi, M. L., Gennari, L., Matucci‐Cerinic, M., Becherini, L., Falchetti, A., Masi, L., Gennari, C., & Reginster, J. (2001) · Arthritis Research · doi:10.1186/ar316 · Cited by 34

Ageing of Bone: its Relation to Osteoporosis and Osteoarthrosis in Post-Menopausal Women

Dequeker, J., Burssens, A., Creytens, G., & Bouillon, R. (2015) · Frontiers of hormone research · doi:10.1159/000398271 · Cited by 32

Levels of insulin related growth factor 1 in osteoarthritis of the knee.

McAlindon, T. E., Teale, J. D., & Dieppe, P. A. (1993) · Annals of the Rheumatic Diseases · doi:10.1136/ard.52.3.229 · Cited by 30

New bone formation in acromegaly: pathogenetic implications for diffuse idiopathic skeletal hyperostosis.

Littlejohn, G. O., Hall, S., Ca, B., & Davidson, A. (1986) · PubMed · Cited by 30

The chingford study

Schwarz, K. (1981) · Public Health · doi:10.1016/s0033-3506(81)80007-8 · Cited by 28

Bone histomorphometry of the iliac crest, and spinal fracture prevalence in atrophic and hypertrophic osteoarthritis of the hip

Schnitzler, C. M., Mesquita, J. M., & Wane, L. (1992) · Osteoporosis International · doi:10.1007/bf01623925 · Cited by 27

Implications of increased bone density in osteoarthritis

Hamerman, D., & Stanley, E. R. (1996) · Journal of Bone and Mineral Research · doi:10.1002/jbmr.5650110903 · Cited by 27

The Ratio of Osteocytic Incorporation to Bone Matrix Formation in Femoral Neck Cancellous Bone: An Enhanced Osteoblast Work Rate in the Vicinity of Hip Osteoarthritis

Jordan, G. R., Loveridge, N., Power, J., Clarke, M., Parker, M. J., & REEVE, J. (2003) · Calcified Tissue International · doi:10.1007/s00223-001-2134-3 · Cited by 26

The relation between osteoporosis of the spine and osteoarthritis of the knee

Yokozeki, H., Igarashi, M., Karube, S., Shiraki, M., & Kurokawa, T. (1995) · International Orthopaedics · doi:10.1007/bf00181109 · Cited by 12

Low plasma zinc levels in active rheumatoid arthritis.

Weinstein, A. (1998) · PubMed · Cited by 7

The effects of interferon-beta treatment of synovial inflammation and expression of metalloproteinases in patients with rheumatoid arthritis

Gravellese (2000) · Pure Amsterdam UMC · doi:10.1002/1529-0131(200002)43:2 · Cited by 2

TGF-β and osteoarthritis

Blaney Davidson, E. N., van der Kraan, P. M., & van den Berg, W. B. (2007) · Osteoarthritis and Cartilage · doi:10.1016/j.joca.2007.02.005 · Cited by 405

Improving subchondral bone integrity reduces progression of cartilage damage in experimental osteoarthritis preceded by osteoporosis

Bellido, M., Lugo, L., Roman-Blas, J. A., Castañeda, S., Calvo, E., Largo, R., & Herrero-Beaumont, G. (2011) · Osteoarthritis and Cartilage · doi:10.1016/j.joca.2011.07.003 · Cited by 134