Diversity among POU transcription factors in chromatin recognition and cell fate reprogramming

Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors

Takahashi, K., & Yamanaka, S. (2006) · Cell · doi:10.1016/j.cell.2006.07.024 · Cited by 26,673 · see citing works

Induction of Pluripotent Stem Cells from Adult Human Fibroblasts by Defined Factors

Takahashi, K., Tanabe, K., Ohnuki, M., Narita, M., Ichisaka, T., Tomoda, K., & Yamanaka, S. (2007) · Cell · doi:10.1016/j.cell.2007.11.019 · Cited by 20,221 · see citing works

Simple Combinations of Lineage-Determining Transcription Factors Prime cis-Regulatory Elements Required for Macrophage and B Cell Identities

Heinz, S., Benner, C., Spann, N., Bertolino, E., Lin, Y. C., Laslo, P., Cheng, J. X., Murre, C., Singh, H., & Glass, C. K. (2010) · Molecular Cell · doi:10.1016/j.molcel.2010.05.004 · Cited by 13,382 · see citing works

Induced Pluripotent Stem Cell Lines Derived from Human Somatic Cells

Yu, J., Vodyanik, M. A., Smuga-Otto, K., Antosiewicz-Bourget, J., Frane, J. L., Tian, S., Nie, J., Jonsdottir, G. A., Ruotti, V., Stewart, R., et al. (2007) · Science · doi:10.1126/science.1151526 · Cited by 10,310 · see citing works

A bivalent chromatin structure marks key developmental genes in embryonic stem cells

Bernstein, B. E., Mikkelsen, T. S., Xie, X., Kamal, M., Huebert, D. J., Cuff, J., Fry, B., Meissner, A., Wernig, M., Plath, K., et al. (2006) · Cell · doi:10.1016/j.cell.2006.02.041 · Cited by 5,361 · see citing works

Core Transcriptional Regulatory Circuitry in Human Embryonic Stem Cells

Boyer, L. A., Lee, T. I., Cole, M. F., Johnstone, S. E., Levine, S. S., Zucker, J. P., Guenther, M. G., Kumar, R. M., Murray, H. L., Jenner, R. G., et al. (2005) · Cell · doi:10.1016/j.cell.2005.08.020 · Cited by 4,505 · see citing works

Genome-wide maps of chromatin state in pluripotent and lineage-committed cells

Mikkelsen, T. S., Ku, M., Jaffe, D. B., Issac, B., Lieberman, E., Giannoukos, G., Alvarez, P., Brockman, W., Kim, T.-K., Koche, R. P., et al. (2007) · Nature · doi:10.1038/nature06008 · Cited by 4,129 · see citing works

Quantitative expression of Oct-3/4 defines differentiation, dedifferentiation or self-renewal of ES cells

Niwa, H., Miyazaki, J., & Smith, A. G. (2000) · Nature Genetics · doi:10.1038/74199 · Cited by 3,606 · see citing works

Formation of Pluripotent Stem Cells in the Mammalian Embryo Depends on the POU Transcription Factor Oct4

Nichols, J., Zevnik, B., Anastassiadis, K., Niwa, H., Klewe-Nebenius, D., Chambers, I., Schöler, H. R., & Smith, A. G. (1998) · Cell · doi:10.1016/s0092-8674(00)81769-9 · Cited by 3,394 · see citing works

Reprogramming of human somatic cells to pluripotency with defined factors

Park, I.-H., Zhao, R., West, J. A., Yabuuchi, A., Huo, H.-G., Ince, T., Lerou, P., Lensch, M., & Daley, G. Q. (2008) · Nature · doi:10.1038/nature06534 · Cited by 3,028 · see citing works

Direct conversion of fibroblasts to functional neurons by defined factors

Vierbuchen, T., Ostermeier, A., Pang, Z. P., Kokubu, Y., Südhof, T. C., & Wernig, M. (2010) · Nature · doi:10.1038/nature08797 · Cited by 3,017 · see citing works

Generation of induced pluripotent stem cells without Myc from mouse and human fibroblasts

Nakagawa, M., Koyanagi, M., Tanabe, K., Takahashi, K., Ichisaka, T., Aoi, T., Okita, K., Mochiduki, Y., Takizawa, N., & Yamanaka, S. (2007) · Nature Biotechnology · doi:10.1038/nbt1374 · Cited by 2,781 · see citing works

Integration of External Signaling Pathways with the Core Transcriptional Network in Embryonic Stem Cells

Chen, X., Han, X., Yuan, P., Fang, F., Huss, M., Vega, V. B., Wong, E., Orlov, Y. L., Zhang, W., Jiang, J., et al. (2008) · Cell · doi:10.1016/j.cell.2008.04.043 · Cited by 2,474 · see citing works

The Oct4 and Nanog transcription network regulates pluripotency in mouse embryonic stem cells

Loh, Y., Wu, Q., Chew, J.-L., Vega, V. B., Zhang, W., Chen, X., Bourque, G., George, J., Leong, B., Liu, J., et al. (2006) · Nature Genetics · doi:10.1038/ng1760 · Cited by 2,438 · see citing works

Disease-Specific Induced Pluripotent Stem Cells.

Park, I.-H., Arora, N., Huo, H., Maherali, N., Ahfeldt, T., Shimamura, A., Lensch, M. W., Cowan, C., Hochedlinger, K., & Daley, G. Q. (2008) · Cell · doi:10.1016/j.cell.2008.07.041 · Cited by 2,196 · see citing works

Induced Pluripotent Stem Cells Generated from Patients with ALS Can Be Differentiated into Motor Neurons

Dimos, J. T., Rodolfa, K. T., Niakan, K. K., Weisenthal, L. M., Mitsumoto, H., Chung, W. K., Croft, G. F., Saphier, G., Leibel, R. L., Goland, R., et al. (2008) · Science · doi:10.1126/science.1158799 · Cited by 1,959 · see citing works

Mediator and cohesin connect gene expression and chromatin architecture

Kagey, M. H., Newman, J. J., Bilodeau, S., Zhan, Y., Orlando, D. A., van Berkum, N. L., Ebmeier, C. C., Goossens, J., Rahl, P. B., Levine, S. S., et al. (2010) · Nature · doi:10.1038/nature09380 · Cited by 1,939 · see citing works

Determination and Inference of Eukaryotic Transcription Factor Sequence Specificity

Weirauch, M. T., Yang, A. W. H., Albu, M., Coté, A. G., Montenegro‐Montero, A., Drewe, P., Najafabadi, H. S., Lambert, S. A., Mann, I. K., Cook, K. B., et al. (2014) · Cell · doi:10.1016/j.cell.2014.08.009 · Cited by 1,705 · see citing works

Induced pluripotent stem cells generated without viral integration

Stadtfeld, M., Nagaya, M., Utikal, J., Weir, G., & Hochedlinger, K. (2008) · Science · doi:10.1126/science.1162494 · Cited by 1,683 · see citing works

Parkinson’s Disease Patient-Derived Induced Pluripotent Stem Cells Free of Viral Reprogramming Factors

Soldner, F., Hockemeyer, D., Beard, C., Gao, Q., Bell, G. W., Cook, E. G., Hargus, G., Blak, A., Cooper, O., Mitalipova, M., et al. (2009) · Cell · doi:10.1016/j.cell.2009.02.013 · Cited by 1,615 · see citing works

Induced pluripotent stem cells from a spinal muscular atrophy patient

Ebert, A. D., Yu, J., Rose, F. F., Mattis, V. B., Lorson, C. L., Thomson, J. A., & Svendsen, C. N. (2009) · Nature · doi:10.1038/nature07677 · Cited by 1,441 · see citing works

Efficient and rapid generation of induced pluripotent stem cells from human keratinocytes

Aasen, T., Raya, A., Barrero, M. J., Garreta, E., Consiglio, A., Gonzalez, F., Vassena, R., Bilić, J., Pekarik, V., Tiscornia, G., et al. (2008) · Nature Biotechnology · doi:10.1038/nbt.1503 · Cited by 1,423 · see citing works

Chromatin signatures of pluripotent cell lines

Azuara, V., Perry, P., Sauer, S., Spivakov, M., Jørgensen, H. F., John, R. M., Gouti, M., Casanova, M., Warnes, G., Merkenschlager, M., et al. (2006) · Nature Cell Biology · doi:10.1038/ncb1403 · Cited by 1,357 · see citing works

Induction of pluripotent stem cells from primary human fibroblasts with only Oct4 and Sox2

Huangfu, D., Osafune, K., Maehr, R., Guo, W., Eijkelenboom, A., Chen, S., Muhlestein, W. E., & Melton, D. A. (2008) · Nature Biotechnology · doi:10.1038/nbt.1502 · Cited by 1,342 · see citing works

Deep mutational scanning: a new style of protein science

Fowler, D. M., & Fields, S. (2014) · Nature Methods · doi:10.1038/nmeth.3027 · Cited by 1,287 · see citing works

Co-crystal structure of the HNF-3/fork head DNA-recognition motif resembles histone H5

Clark, K., Halay, E. D., Lai, E., & Burley, S. K. (1993) · Nature · doi:10.1038/364412a0 · Cited by 1,275 · see citing works

Impact of cytosine methylation on DNA binding specificities of human transcription factors

Yin, Y., Morgunova, E., Jolma, A., Kaasinen, E., Sahu, B., Khund-Sayeed, S., Das, P. K., Kivioja, T., Dave, K., Zhong, F., et al. (2017) · Science · doi:10.1126/science.aaj2239 · Cited by 1,257 · see citing works

Induction of human neuronal cells by defined transcription factors

Pang, Z. P., Yang, N., Vierbuchen, T., Ostermeier, A., Fuentes, D., Yang, T. Q., Citri, A., Sebastiano, V., Marro, S. G., Südhof, T. C., et al. (2011) · Nature · doi:10.1038/nature10202 · Cited by 1,249 · see citing works

DNA-Binding Specificities of Human Transcription Factors

Jolma, A., Yan, J., Whitington, T., Toivonen, J., Nitta, K. R., Rastas, P. M. A., Morgunova, E. Y., Enge, M., Taipale, M., Wei, G., et al. (2013) · Cell · doi:10.1016/j.cell.2012.12.009 · Cited by 1,228 · see citing works

Opening of Compacted Chromatin by Early Developmental Transcription Factors HNF3 (FoxA) and GATA-4

Cirillo, L. A., Lin, F. R., Cuesta, I., Friedman, D., Jarník, M., & Zaret, K. S. (2002) · Molecular Cell · doi:10.1016/s1097-2765(02)00459-8 · Cited by 1,188 · see citing works

Transcriptional Regulation of Nanog by OCT4 and SOX2

Rodda, D. J., Chew, J.-L., Lim, L. H., Loh, Y., Wang, B., Ng, H., & Robson, P. (2005) · Journal of Biological Chemistry · doi:10.1074/jbc.m502573200 · Cited by 1,140 · see citing works

Genome-Wide Quantitative Enhancer Activity Maps Identified by STARR-seq

Arnold, C. D., Gerlach, D., Stelzer, C., Boryń, Ł. M., Rath, M., & Stark, A. (2013) · Science · doi:10.1126/science.1232542 · Cited by 1,125 · see citing works

Linking the p53 tumour suppressor pathway to somatic cell reprogramming

Kawamura, T., Suzuki, J., Wang, Y. V., Menendez, S., Morera, L. B., Raya, A., Wahl, G. M., & Belmonte, J. C. I. (2009) · Nature · doi:10.1038/nature08311 · Cited by 1,115 · see citing works

Generation of Pluripotent Stem Cells from Adult Mouse Liver and Stomach Cells

Aoi, T., Yae, K., Nakagawa, M., Ichisaka, T., Okita, K., Takahashi, K., Chiba, T., & Yamanaka, S. (2008) · Science · doi:10.1126/science.1154884 · Cited by 1,055 · see citing works

Generation of human induced pluripotent stem cells from dermal fibroblasts

Lowry, W. E., Richter, L., Yachechko, R., Pyle, A. D., Tchieu, J., Sridharan, R., Clark, A. T., & Plath, K. (2008) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0711983105 · Cited by 1,041 · see citing works

Diversity and Complexity in DNA Recognition by Transcription Factors

Badis, G., Berger, M., Philippakis, A. A., Talukder, S., Gehrke, A. R., Jaeger, S., Chan, E. T., Metzler, G., Vedenko, A., Chen, X., et al. (2009) · Science · doi:10.1126/science.1162327 · Cited by 1,031 · see citing works

Stepwise reprogramming of B cells into macrophages.

Xie, H.-F., Ye, M., Feng, R., & Graf, T. (2004) · Cell · doi:10.1016/s0092-8674(04)00419-2 · Cited by 1,030 · see citing works

Activation of muscle-specific genes in pigment, nerve, fat, liver, and fibroblast cell lines by forced expression of MyoD.

Weintraub, H. M., Tapscott, S. J., Davis, R. L., Thayer, M. J., Adam, M. A., Lassar, A. B., & Miller, A. D. (1989) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.86.14.5434 · Cited by 985 · see citing works

A tissue-specific transcription factor containing a homeodomain specifies a pituitary phenotype

Ingraham, H. A., Chen, R., Mangalam, H. J., Elsholtz, H. P., Flynn, S. E., Lin, C. R., Simmons, D. M., Swanson, L. W., & Rosenfeld, M. G. (1988) · Cell · doi:10.1016/0092-8674(88)90038-4 · Cited by 978 · see citing works

The Ink4/Arf locus is a barrier for iPS cell reprogramming

Li, H., Collado, M., Villasante, A., Strati, K., Ortega, S., Cañamero, M., Blasco, M. A., & Serrano, M. (2009) · Nature · doi:10.1038/nature08290 · Cited by 968 · see citing works

Pluripotent stem cells induced from adult neural stem cells by reprogramming with two factors

Kim, J. B., Zaehres, H., Wu, G., Gentile, L., Ko, K., Sebastiano, V., Araúzo-Bravo, M. J., Ruau, D., Han, D., Zenke, M., et al. (2008) · Nature · doi:10.1038/nature07061 · Cited by 956 · see citing works

A homologous protein-coding sequence in drosophila homeotic genes and its conservation in other metazoans

McGinnis, W. J., Garber, R. L., Wirz, J., Kuroiwa, A., & Gehring, W. J. (1984) · Cell · doi:10.1016/0092-8674(84)90370-2 · Cited by 941 · see citing works

Oct4-Induced Pluripotency in Adult Neural Stem Cells

Kim, J. B., Sebastiano, V., Wu, G., Araúzo-Bravo, M. J., Sasse, P., Gentile, L., Ko, K., Ruau, D., Ehrich, M., van den Boom, D., et al. (2009) · Cell · doi:10.1016/j.cell.2009.01.023 · Cited by 931 · see citing works

MicroRNA-mediated conversion of human fibroblasts to neurons

Yoo, A. S., Sun, A. X., Li, L., Shcheglovitov, A., Portmann, T., Li, Y., Lee-Messer, C., Dolmetsch, R. E., Tsien, R. W., & Crabtree, G. R. (2011) · Nature · doi:10.1038/nature10323 · Cited by 919 · see citing works

Induction of Pluripotent Stem Cells from Mouse Embryonic Fibroblasts by Oct4 and Klf4 with Small-Molecule Compounds

Shi, Y., Desponts, C., Tae, J., Hahm, H. S., Schöler, H. R., & Ding, S. (2008) · Cell stem cell · doi:10.1016/j.stem.2008.10.004 · Cited by 898 · see citing works

Facilitators and Impediments of the Pluripotency Reprogramming Factors' Initial Engagement with the Genome

Soufi, A., Donahue, G., & Zaret, K. S. (2012) · Cell · doi:10.1016/j.cell.2012.09.045 · Cited by 887 · see citing works

Modelling pathogenesis and treatment of familial dysautonomia using patient-specific iPSCs

Lee, G., Papapetrou, E. P., Kim, H., Chambers, S. M., Tomishima, M. J., Fasano, C. A., Ganat, Y. M., Menon, J., Shimizu, F., Viale, A. J., et al. (2009) · Nature · doi:10.1038/nature08320 · Cited by 870 · see citing works

SOX17 Is a Critical Specifier of Human Primordial Germ Cell Fate

Irie, N., Weinberger, L., Tang, W. W. C., Kobayashi, T., Viukov, S. V., Manor, Y. S., Dietmann, S., Hanna, J. H., & Surani, M. A. (2014) · Cell · doi:10.1016/j.cell.2014.12.013 · Cited by 839 · see citing works

Expression of a large family of POU-domain regulatory genes in mammalian brain development

He, X., Treacy, M. N., Simmons, D. M., Ingraham, H. A., Swanson, L. W., & Rosenfeld, M. G. (1989) · Nature · doi:10.1038/340035a0 · Cited by 830 · see citing works

Direct Reprogramming of Terminally Differentiated Mature B Lymphocytes to Pluripotency

Hanna, J. H., Markoulaki, S., Schorderet, P., Carey, B. W., Beard, C., Wernig, M., Creyghton, M. P., Steine, E. J., Cassady, J. P., Foreman, R. K., et al. (2008) · Cell · doi:10.1016/j.cell.2008.03.028 · Cited by 815 · see citing works

Developmental-specific activity of the FGF-4 enhancer requires the synergistic action of Sox2 and Oct-3.Preprint

Yuan, H., Corbi, N., Basilico, C., & Dailey, L. (1995) · Genes & Development · doi:10.1101/gad.9.21.2635 · Cited by 811 · see citing works

Promotion of Reprogramming to Ground State Pluripotency by Signal Inhibition

Silva, J., Barrandon, O., Nichols, J., Kawaguchi, J., Theunissen, T. W., & Smith, A. G. (2008) · PLoS Biology · doi:10.1371/journal.pbio.0060253 · Cited by 810 · see citing works

Structural relationships among genes that control development: sequence homology between the Antennapedia, Ultrabithorax, and fushi tarazu loci of Drosophila.

Scott, M. P., & Weiner, A. J. (1984) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.81.13.4115 · Cited by 790 · see citing works

Sox10, a Novel Transcriptional Modulator in Glial Cells

Kuhlbrodt, K., Herbarth, B., Sock, E., Hermans-Borgmeyer, I., & Wegner, M. (1998) · The Journal of Neuroscience · doi:10.1523/jneurosci.18-01-00237.1998 · Cited by 781 · see citing works

Pioneer Transcription Factors Target Partial DNA Motifs on Nucleosomes to Initiate Reprogramming

Soufi, A., Garcia, M. F., Jaroszewicz, A., Osman, N., Pellegrini, M., & Zaret, K. S. (2015) · Cell · doi:10.1016/j.cell.2015.03.017 · Cited by 780 · see citing works

Transposable elements have rewired the core regulatory network of human embryonic stem cells

Kunarso, G., Chia, N., Jeyakani, J., Hwang, C., Lu, X., Chan, Y.-S., Ng, H., & Bourque, G. (2010) · Nature Genetics · doi:10.1038/ng.600 · Cited by 777 · see citing works

The pituitary-specific transcription factor GHF-1 is a homeobox-containing protein

Bodner, M., Castrillo, J.-L., Theill, L. E., Deerinck, T. J., Ellisman, M. H., & Karin, M. (1988) · Cell · doi:10.1016/0092-8674(88)90037-2 · Cited by 757 · see citing works

New type of POU domain in germ line-specific protein Oct-4

Schöler, H. R., Ruppert, S., Suzuki, N., Chowdhury, K., & Gruß, P. (1990) · Nature · doi:10.1038/344435a0 · Cited by 745 · see citing works

The POU domain: a large conserved region in the mammalian pit-1, oct-1, oct-2, and Caenorhabditis elegans unc-86 gene products.Preprint

Herr, W., Sturm, R. A., Clerc, R. G., Corcoran, L. M., Baltimore, D., Sharp, P. A., Ingraham, H. A., Rosenfeld, M. G., Finney, M., & Ruvkun, G. (1988) · Genes & Development · doi:10.1101/gad.2.12a.1513 · Cited by 743 · see citing works

Direct conversion of human fibroblasts to dopaminergic neurons

Pfisterer, U., Kirkeby, A., Torper, O., Wood, J. C., Nelander, J., Dufour, A., Björklund, A., Lindvall, O., Jakobsson, J., & Parmar, M. (2011) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1105135108 · Cited by 740 · see citing works

Crystal structure of globular domain of histone H5 and its implications for nucleosome binding

Ramakrishnan, V., Finch, J. T., Graziano, V., Lee, P. L., & Sweet, R. M. (1993) · Nature · doi:10.1038/362219a0 · Cited by 736 · see citing works

A novel octamer binding transcription factor is differentially expressed in mouse embryonic cells

Okamoto, K., Okazawa, H., Okuda, A., Sakai, M., Muramatsu, M., & Hamada, H. (1990) · Cell · doi:10.1016/0092-8674(90)90597-8 · Cited by 723 · see citing works

Direct reprogramming of human neural stem cells by OCT4

Kim, J. B., Greber, B., Araúzo-Bravo, M. J., Meyer, J., Park, K. I., Zaehres, H., & Schöler, H. R. (2009) · Nature · doi:10.1038/nature08436 · Cited by 692 · see citing works

Direct conversion of human fibroblasts to multilineage blood progenitors

Szabo, E., Rampalli, S., Risueño, R. M., Schnerch, A., Mitchell, R. R., Fiebig‐Comyn, A., Levadoux‐Martin, M., & Bhatia, M. (2010) · Nature · doi:10.1038/nature09591 · Cited by 691 · see citing works

The ubiquitous octamer-binding protein Oct-1 contains a POU domain with a homeo box subdomain.Preprint

Sturm, R. A., Das, G., & Herr, W. (1988) · Genes & Development · doi:10.1101/gad.2.12a.1582 · Cited by 673 · see citing works

A Combined Chemical and Genetic Approach for the Generation of Induced Pluripotent Stem Cells

Shi, Y., Tae, J., Desponts, C., Hahm, H. S., Schöler, H. R., & Ding, S. (2008) · Cell stem cell · doi:10.1016/j.stem.2008.05.011 · Cited by 669 · see citing works

A lymphoid-specific protein binding to the octamer motif of immunoglobulin genes

Staudt, L. M., Singh, H., Sen, R., Wirth, T. C., Sharp, P. A., & Baltimore, D. (1986) · Nature · doi:10.1038/323640a0 · Cited by 658 · see citing works

Epigenetic memory and preferential lineage-specific differentiation in induced pluripotent stem cells derived from human pancreatic islet beta cells.

Bar-Nur, O., Russ, H., Efrat, S., & Benvenisty, N. (2011) · Cell Stem Cell · doi:10.1016/j.stem.2011.06.007 · Cited by 651 · see citing works

A family of octamer‐specific proteins present during mouse embryogenesis: evidence for germline‐specific expression of an Oct factor.

Schöler, H. R., Hatzopoulos, A. K., Balling, R., Suzuki, N., & Gruss, P. (1989) · The EMBO Journal · doi:10.1002/j.1460-2075.1989.tb08392.x · Cited by 646 · see citing works

Pairing SOX off: with partners in the regulation of embryonic development

Kamachi, Y., Uchikawa, M., & Kondoh, H. (2000) · Trends in Genetics · doi:10.1016/s0168-9525(99)01955-1 · Cited by 641 · see citing works

Reciprocal Transcriptional Regulation of Pou5f1 and Sox2 via the Oct4/Sox2 Complex in Embryonic Stem Cells

Chew, J.-L., Loh, Y., Zhang, W., Chen, X., Tam, W. L., Yeap, L.-S., Li, P., Ang, Y.-S., Lim, B., Robson, P., et al. (2005) · Molecular and Cellular Biology · doi:10.1128/mcb.25.14.6031-6046.2005 · Cited by 641 · see citing works

c-Myc Is Dispensable for Direct Reprogramming of Mouse Fibroblasts

Wernig, M., Meissner, A., Cassady, J. P., & Jaenisch, R. (2008) · Cell stem cell · doi:10.1016/j.stem.2007.12.001 · Cited by 627 · see citing works

Hierarchical Mechanisms for Direct Reprogramming of Fibroblasts to Neurons

Wapinski, O. L., Vierbuchen, T., Qu, K., Lee, Q. Y., Chanda, S., Fuentes, D. R., Giresi, P. G., Ng, Y. H., Marro, S., Neff, N. F., et al. (2013) · Cell · doi:10.1016/j.cell.2013.09.028 · Cited by 627 · see citing works

An Atomic Model of the Interferon-β Enhanceosome

Panne, D., Maniatis, T., & Harrison, S. C. (2007) · Cell · doi:10.1016/j.cell.2007.05.019 · Cited by 625 · see citing works

Conversion of mouse fibroblasts into cardiomyocytes using a direct reprogramming strategy

Efe, J. A., Hilcove, S. A., Kim, J., Zhou, H., Ouyang, K., Wang, G., Chen, J., & Ding, S. (2011) · Nature Cell Biology · doi:10.1038/ncb2164 · Cited by 618 · see citing works

Cryo-EM Study of the Chromatin Fiber Reveals a Double Helix Twisted by Tetranucleosomal Units

Song, F., Chen, P., Sun, D., Wang, M., Dong, L., Liang, D., Xu, R.-M., Zhu, P., & Li, G. (2014) · Science · doi:10.1126/science.1251413 · Cited by 617 · see citing works

Generation of human induced pluripotent stem cells from urine samples

Zhou, T., Benda, C., Dunzinger, S., Huang, Y., Ho, J. C., Yang, J., Wang, Y., Zhang, Y., Zhuang, Q., Li, Y., et al. (2012) · Nature Protocols · doi:10.1038/nprot.2012.115 · Cited by 614 · see citing works

Single-Molecule Dynamics of Enhanceosome Assembly in Embryonic Stem Cells

Chen, J., Zhang, Z., Li, L., Chen, B.-C., Revyakin, A., Hajj, B., Legant, W., Dahan, M., Lionnet, T., Betzig, E., et al. (2014) · Cell · doi:10.1016/j.cell.2014.01.062 · Cited by 602 · see citing works

Hepatic specification of the gut endoderm in vitro: cell signaling and transcriptional control.Preprint

Gualdi, R., Bossard, P., Zheng, M., Hamada, Y., Coleman, J. R., & Zaret, K. S. (1996) · Genes & Development · doi:10.1101/gad.10.13.1670 · Cited by 590 · see citing works

Direct reprogramming of mouse fibroblasts to neural progenitors

Kim, J., Efe, J. A., Zhu, S., Talantova, M. V., Xu, Y., Wang, S., Lipton, S. A., Zhang, K., & Ding, S. (2011) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1103113108 · Cited by 568 · see citing works

A High-Efficiency System for the Generation and Study of Human Induced Pluripotent Stem Cells

Maherali, N., Ahfeldt, T., Rigamonti, A., Utikal, J., Cowan, C., & Hochedlinger, K. (2008) · Cell Stem Cell · doi:10.1016/j.stem.2008.08.003 · Cited by 563 · see citing works

DNA-dependent formation of transcription factor pairs alters their binding specificity

Jolma, A., Yin, Y., Nitta, K. R., Dave, K., Popov, A. N., Taipale, M., Enge, M., Kivioja, T., Morgunova, E. Y., & Taipale, J. (2015) · Nature · doi:10.1038/nature15518 · Cited by 555 · see citing works

Cooperative Binding of Transcription Factors Orchestrates Reprogramming

Chronis, C., Fiziev, P., Papp, B., Butz, S., Bonora, G., Sabri, S., Ernst, J., & Plath, K. (2017) · Cell · doi:10.1016/j.cell.2016.12.016 · Cited by 555 · see citing works

Wdr5 Mediates Self-Renewal and Reprogramming via the Embryonic Stem Cell Core Transcriptional Network

Ang, Y.-S., Tsai, S., Lee, D., Monk, J. M., Su, J., Ratnakumar, K., Ding, J., Ge, Y., Darr, H., Chang, B., et al. (2011) · Cell · doi:10.1016/j.cell.2011.03.003 · Cited by 545 · see citing works

An Oct4-Centered Protein Interaction Network in Embryonic Stem Cells

van den Berg, D. L. C., Snoek, T., Mullin, N. P., Yates, A., Bezstarosti, K., Demmers, J., Chambers, I., & Poot, R. A. (2010) · Cell Stem Cell · doi:10.1016/j.stem.2010.02.014 · Cited by 542 · see citing works

Structure of the 5' ends of immunoglobulin genes: a novel conserved sequence.

Parslow, T. G., Blair, D. L., Murphy, W. J., & Granner, D. K. (1984) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.81.9.2650 · Cited by 529 · see citing works

Generation of induced pluripotent stem cells from human cord blood.

Haase, A., Olmer, R., Schwanke, K., Wunderlich, S., Merkert, S., Hess, C., Zweigerdt, R., Gruh, I., Meyer, J., Wagner, S., et al. (2009) · Cell Stem Cell · doi:10.1016/j.stem.2009.08.021 · Cited by 520 · see citing works

Direct Reprogramming of Fibroblasts into Neural Stem Cells by Defined Factors

Han, D., Tàpia, N., Hermann, A., Hemmer, K., Höing, S., Araúzo-Bravo, M. J., Zaehres, H., Wu, G., Frank, S., Moritz, S., et al. (2012) · Cell stem cell · doi:10.1016/j.stem.2012.02.021 · Cited by 514 · see citing works

Crystal structure of the Oct-1 POU domain bound to an octamer site: DNA recognition with tethered DNA-binding modules

Klemm, J. D., Rould, M. A., Aurora, R., Herr, W., & Pabo, C. O. (1994) · Cell · doi:10.1016/0092-8674(94)90231-3 · Cited by 506 · see citing works

Octamer and Sox Elements Are Required for Transcriptional cis Regulation of Nanog Gene Expression

Kuroda, T., Tada, M., Kubota, H., Kimura, H., Hatano, S.-Y., Suemori, H., Nakatsuji, N., & Tada, T. (2005) · Molecular and Cellular Biology · doi:10.1128/mcb.25.6.2475-2485.2005 · Cited by 490 · see citing works

Purification and characterization of OTF-1, a transcription factor regulating cell cycle expression of a human histone H2b gene

Fletcher, C., Heintz, N., & Roeder, R. G. (1987) · Cell · doi:10.1016/0092-8674(87)90100-0 · Cited by 487 · see citing works

Direct Conversion of Fibroblasts into Stably Expandable Neural Stem Cells

Thier, M. C., Wörsdörfer, P., Lakes, Y. B., Gorris, R., Herms, S., Opitz, T., Seiferling, D., Quandel, T., Hoffmann, P., Nöthen, M. M., et al. (2012) · Cell stem cell · doi:10.1016/j.stem.2012.03.003 · Cited by 485 · see citing works

POU domain family values: flexibility, partnerships, and developmental codes.Preprint

Ryan, A. K., & Rosenfeld, M. G. (1997) · Genes & Development · doi:10.1101/gad.11.10.1207 · Cited by 482 · see citing works

Direct Reprogramming of Adult Human Fibroblasts to Functional Neurons under Defined Conditions

Ambasudhan, R., Talantova, M. V., Coleman, R., Xu, Y., Zhu, S., Lipton, S. A., & Ding, S. (2011) · Cell stem cell · doi:10.1016/j.stem.2011.07.002 · Cited by 480 · see citing works

Reprogramming of fibroblasts into induced pluripotent stem cells with orphan nuclear receptor Esrrb

Feng, B., Jiang, J., Kraus, P., Ng, J.-H., Heng, J.-C. D., Chan, Y.-S., Yaw, L. P., Zhang, W., Loh, Y., Han, J., et al. (2009) · Nature Cell Biology · doi:10.1038/ncb1827 · Cited by 472 · see citing works

Two Supporting Factors Greatly Improve the Efficiency of Human iPSC Generation

Zhao, Y., Yin, X., Qin, H., Zhu, F., Liu, H., Yang, W., Zhang, Q., Xiang, C., Hou, P., Song, Z., et al. (2008) · Cell Stem Cell · doi:10.1016/j.stem.2008.10.002 · Cited by 468 · see citing works

Molecular basis of human 46X,Y sex reversal revealed from the three-dimensional solution structure of the human SRY-DNA complex

Werner, M. H., Huth, J. R., Gronenborn, A. M., & Clore, G. M. (1995) · Cell · doi:10.1016/0092-8674(95)90532-4 · Cited by 464 · see citing works

A cloned octamer transcription factor stimulates transcription from lymphoid–specific promoters in non–B cells

Müller, M. M., Ruppert, S., Schaffner, W., & Matthias, P. (1988) · Nature · doi:10.1038/336544a0 · Cited by 462 · see citing works

POU-domain transcription factors: pou-er-ful developmental regulators.Preprint

Rosenfeld, M. G. (1991) · Genes & Development · doi:10.1101/gad.5.6.897 · Cited by 456 · see citing works

Classification and nomenclature of all human homeobox genes

Holland, P. W., Booth, H. A. F., & Bruford, E. A. (2007) · BMC Biology · doi:10.1186/1741-7007-5-47 · Cited by 443 · see citing works

Differentiation stage determines potential of hematopoietic cells for reprogramming into induced pluripotent stem cells

Eminli, S., Foudi, A., Stadtfeld, M., Maherali, N., Ahfeldt, T., Mostoslavsky, G., Hock, H. R., & Hochedlinger, K. (2009) · Nature Genetics · doi:10.1038/ng.428 · Cited by 438 · see citing works

Direct conversion of mouse fibroblasts to self-renewing, tripotent neural precursor cells

Lujan, E., Chanda, S., Ahlenius, H., Südhof, T. C., & Wernig, M. (2012) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1121003109 · Cited by 421 · see citing works

The B-cell-specific Oct-2 protein contains POU box- and homeo box-type domains.Preprint

Clerc, R. G., Corcoran, L. M., LeBowitz, J. H., Baltimore, D., & Sharp, P. A. (1988) · Genes & Development · doi:10.1101/gad.2.12a.1570 · Cited by 409 · see citing works

Generation of Induced Pluripotent Stem Cells from Human Cord Blood Using OCT4 and SOX2

Giorgetti, A., Montserrat, N., Aasen, T., Gonzãlez, F., Rodríguez‐Pizà, I., Vassena, R., Raya, Á., Boué, S., Barrero, M. J., Arán, B., et al. (2009) · Cell stem cell · doi:10.1016/j.stem.2009.09.008 · Cited by 407 · see citing works

Crystal structure of a POU/HMG/DNA ternary complex suggests differential assembly of Oct4 and Sox2 on two enhancersPreprint

Reményi, A., Lins, K., Nissen, L. J., Reinbold, R. A., Schöler, H. R., & Wilmanns, M. (2003) · Genes & Development · doi:10.1101/gad.269303 · Cited by 392 · see citing works

Direct reprogramming of somatic cells is promoted by maternal transcription factor Glis1

Maekawa, M., Yamaguchi, K., Nakamura, T., Shibukawa, R., Kodanaka, I., Ichisaka, T., Kawamura, Y., Mochizuki, H., Goshima, N., & Yamanaka, S. (2011) · Nature · doi:10.1038/nature10106 · Cited by 388 · see citing works

The POU domain: versatility in transcriptional regulation by a flexible two-in-one DNA-binding domain.

Herr, W., & Cleary, M. A. (1995) · Genes & Development · doi:10.1101/gad.9.14.1679 · Cited by 388 · see citing works

Oct-3/4 and Sox2 Regulate Oct-3/4 Gene in Embryonic Stem Cells

Okumura-Nakanishi, S., Saito, M., Niwa, H., & Ishikawa, F. (2004) · Journal of Biological Chemistry · doi:10.1074/jbc.m410015200 · Cited by 387 · see citing works

Identification and purification of a human lymphoid-specific octamer-binding protein (OTF-2) that activates transcription of an immunoglobulin promoter in vitro

Scheidereit, C., Heguy, A., & Roeder, R. G. (1987) · Cell · doi:10.1016/0092-8674(87)90101-2 · Cited by 384 · see citing works

Binding of the winged‐helix transcription factor HNF3 to a linker histone site on the nucleosome

Cirillo, L. A., McPherson, C. E., Bossard, P., Stevens, K., Cherian, S., Shim, E. Y., Clark, K., Burley, S. K., & Zaret, K. S. (1998) · The EMBO Journal · doi:10.1093/emboj/17.1.244 · Cited by 381 · see citing works

An Expanded Oct4 Interaction Network: Implications for Stem Cell Biology, Development, and Disease

Pardo, M., Lang, B., Yu, L., Prosser, H., Bradley, A., Babu, M. M., & Choudhary, J. (2010) · Cell Stem Cell · doi:10.1016/j.stem.2010.03.004 · Cited by 379 · see citing works

Octamania: The POU factors in murine development

Schöler, H. R. (1991) · Trends in Genetics · doi:10.1016/0168-9525(91)90422-m · Cited by 372 · see citing works

The Gene for the Embryonic Stem Cell Coactivator UTF1 Carries a Regulatory Element Which Selectively Interacts with a Complex Composed of Oct-3/4 and Sox-2

Nishimoto, M., Fukushima, A., Okuda, A., & Muramatsu, M. (1999) · Molecular and Cellular Biology · doi:10.1128/mcb.19.8.5453 · Cited by 368 · see citing works

Synergistic Activation of the Fibroblast Growth Factor 4 Enhancer by Sox2 and Oct-3 Depends on Protein-Protein Interactions Facilitated by a Specific Spatial Arrangement of Factor Binding Sites

Ambrosetti, D. C., Basilico, C., & Dailey, L. (1997) · Molecular and Cellular Biology · doi:10.1128/mcb.17.11.6321 · Cited by 368 · see citing works

Reprogramming Factor Expression Initiates Widespread Targeted Chromatin Remodeling

Koche, R. P., Smith, Z. D., Adli, M., Gu, H., Ku, M., Gnirke, A., Bernstein, B., & Meissner, A. (2011) · Cell stem cell · doi:10.1016/j.stem.2010.12.001 · Cited by 367 · see citing works

Reprogramming of murine fibroblasts to induced pluripotent stem cells with chemical complementation of Klf4

Lyssiotis, C. A., Foreman, R. K., Staerk, J., Garcia, M. E., Mathur, D., Markoulaki, S., Hanna, J. H., Lairson, L. L., Charette, B. D., Bouchez, L. C., et al. (2009) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0903860106 · Cited by 367 · see citing works

Generation of iPSCs from mouse fibroblasts with a single gene, Oct4, and small molecules

Li, Y., Zhang, Q., Yin, X., Yang, W., Du, Y., Hou, P., Ge, J., Liu, C., Zhang, W., Zhang, X., et al. (2010) · Cell Research · doi:10.1038/cr.2010.142 · Cited by 365 · see citing works

A human lymphoid- specific transcription factor that activates immunoglobulin genes is a homoeobox protein

Scheidereit, C., Cromlish, J. A., Gerster, T., Kawakami, K., Balmaceda, C.-G., Currie, R. A., & Roeder, R. G. (1988) · Nature · doi:10.1038/336551a0 · Cited by 364 · see citing works

Tgfβ Signal Inhibition Cooperates in the Induction of iPSCs and Replaces Sox2 and cMyc

Maherali, N., & Hochedlinger, K. (2009) · Current Biology · doi:10.1016/j.cub.2009.08.025 · Cited by 348 · see citing works

Sox2 is dispensable for the reprogramming of melanocytes and melanoma cells into induced pluripotent stem cells

Utikal, J., Maherali, N., Kulalert, W., & Hochedlinger, K. (2009) · Journal of Cell Science · doi:10.1242/jcs.054783 · Cited by 348 · see citing works

The H3K27 demethylase Utx regulates somatic and germ cell epigenetic reprogramming

Mansour, A. A., Gafni, O., Weinberger, L., Zviran, A., Ayyash, M., Rais, Y., Krupalnik, V., Zerbib, M., Amann‐Zalcenstein, D., Maza, I., et al. (2012) · Nature · doi:10.1038/nature11272 · Cited by 344 · see citing works

Direct Lineage Conversion of Terminally Differentiated Hepatocytes to Functional Neurons

Marro, S. G., Pang, Z. P., Yang, N., Tsai, M.-C., Qu, K., Chang, H. Y., Südhof, T. C., & Wernig, M. (2011) · Cell stem cell · doi:10.1016/j.stem.2011.09.002 · Cited by 343 · see citing works

iPS Cells Reprogrammed From Human Mesenchymal-Like Stem/Progenitor Cells of Dental Tissue Origin

Yan, X., Qin, H., Qu, C., Tuan, R. S., Shi, S., & Huang, G. T. ‐. (2009) · Stem Cells and Development · doi:10.1089/scd.2009.0314 · Cited by 341 · see citing works

Pioneer transcription factors, chromatin dynamics, and cell fate control

Zaret, K. S., & Mango, S. E. (2016) · Current Opinion in Genetics & Development · doi:10.1016/j.gde.2015.12.003 · Cited by 337 · see citing works

The C. elegans cell lineage and differentiation gene unc-86 encodes a protein with a homeodomain and extended similarity to transcription factors

Finney, M., Ruvkun, G., & Horvitz, H. R. (1988) · Cell · doi:10.1016/0092-8674(88)90132-8 · Cited by 332 · see citing works

O-GlcNAc Regulates Pluripotency and Reprogramming by Directly Acting on Core Components of the Pluripotency Network

Jang, H., Kim, T. W., Yoon, S., Choi, S., Kang, T.-W., Kim, S., Kwon, Y., Cho, E., & Youn, H. (2012) · Cell stem cell · doi:10.1016/j.stem.2012.03.001 · Cited by 318 · see citing works

New POU dimer configuration mediates antagonistic control of an osteopontin preimplantation enhancer by Oct-4 and Sox-2Preprint

Botquin, V., Hess, H., Fuhrmann, G., Anastassiadis, K., Gross, M. K., Vriend, G., & Schöler, H. R. (1998) · Genes & Development · doi:10.1101/gad.12.13.2073 · Cited by 314 · see citing works

DNA-dependent formation of transcription factor pairs alters their binding specificity

Jolma, A., Yin, Y., Nitta, K. R., Dave, K., Popov, A. N., Taipale, M., Enge, M., Kivioja, T., Morgunova, E. Y., & Taipale, J. (2016) · Nature · doi:10.1038/nature18912 · Cited by 314 · see citing works

Identification of Sox-2 regulatory region which is under the control of Oct-3/4-Sox-2 complex

Tomioka, M. (2002) · Nucleic Acids Research · doi:10.1093/nar/gkf435 · Cited by 307 · see citing works

Matching SOX: partner proteins and co-factors of the SOX family of transcriptional regulators

Wilson, M. J., & Koopman, P. A. (2002) · Current Opinion in Genetics & Development · doi:10.1016/s0959-437x(02)00323-4 · Cited by 307 · see citing works

Structure and Dynamics of a 197 bp Nucleosome in Complex with Linker Histone H1

Bednář, J., Garcia-Saez, I., Boopathi, R., Cutter, A. R., Pápai, G., Reymer, A., Syed, S. H., Lone, I. N., Tonchev, O., Crucifix, C., et al. (2017) · Molecular Cell · doi:10.1016/j.molcel.2017.04.012 · Cited by 297 · see citing works

Interaction of cell-type-specific nuclear proteins with immunoglobulin VH promoter region sequences

Landolfi, N. F., Capra, J. D., & Tucker, P. W. (1986) · Nature · doi:10.1038/323548a0 · Cited by 293 · see citing works

Probing Allostery Through DNA

Kim, S., Broströmer, E., Xing, D., Jin, J., Chong, S., Ge, H., Wang, S. S., Gu, C., Yang, L., Gao, Y. Q., et al. (2013) · Science · doi:10.1126/science.1229223 · Cited by 293 · see citing works

SCIP: A glial POU domain gene regulated by cyclic AMP

Monuki, E. S., Weinmaster, G., Kuhn, R., & Lemke, G. (1989) · Neuron · doi:10.1016/0896-6273(89)90247-x · Cited by 292 · see citing works

Cloning of a Lymphoid-Specific cDNA Encoding a Protein Binding the Regulatory Octamer DNA Motif

Staudt, L. M., Clerc, R. G., Singh, H., LeBowitz, J. H., Sharp, P. A., & Baltimore, D. (1988) · Science · doi:10.1126/science.3399892 · Cited by 289 · see citing works

OCT4 Spliced Variants Are Differentially Expressed in Human Pluripotent and Nonpluripotent Cells

Atlasi, Y., Mowla, S. J., Ziaee, S. A. M., Gokhale, P. J., & Andrews, P. W. (2008) · Stem Cells · doi:10.1634/stemcells.2008-0530 · Cited by 287 · see citing works

Human Oct3 gene family: cDNA sequences, alternative splicing, gene organization, chromosomal location, and expression at low levels in adult tissues

Takeda, J., Seino, S., & Bell, G. I. (1992) · Nucleic Acids Research · doi:10.1093/nar/20.17.4613 · Cited by 286 · see citing works

Development and survival of the endocrine hypothalamus and posterior pituitary gland requires the neuronal POU domain factor Brn-2.Preprint

Schonemann, M. D., Ryan, A. K., McEvilly, R. J., O’Connell, S. M., Arias, C., Kalla, K. A., Li, P., Sawchenko, P. E., & Rosenfeld, M. G. (1995) · Genes & Development · doi:10.1101/gad.9.24.3122 · Cited by 283 · see citing works

POU domain transcription factors

Verrijzer, C. P., & van der Vliet, P. C. (1993) · Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression · doi:10.1016/0167-4781(93)90237-8 · Cited by 281 · see citing works

Interplay of SOX and POU Factors in Regulation of the Nestin Gene in Neural Primordial Cells

Tanaka, S., Kamachi, Y., Tanouchi, A., Hamada, H., Jing, N., & Kondoh, H. (2004) · Molecular and Cellular Biology · doi:10.1128/mcb.24.20.8834-8846.2004 · Cited by 277 · see citing works

Fbx15 Is a Novel Target of Oct3/4 but Is Dispensable for Embryonic Stem Cell Self-Renewal and Mouse Development

Tokuzawa, Y., Kaiho, E., Maruyama, M., Takahashi, K., Mitsui, K., Maeda, M., Niwa, H., & Yamanaka, S. (2003) · Molecular and Cellular Biology · doi:10.1128/mcb.23.8.2699-2708.2003 · Cited by 269 · see citing works

The DNA binding specificity of the bipartite POU domain and its subdomains.

Verrijzer, C. P., Alkema, M. J., van Weperen, W. W., van Leeuwen, H. C., Strating, M., & van der Vliet, P. C. (1992) · The EMBO Journal · doi:10.1002/j.1460-2075.1992.tb05606.x · Cited by 266 · see citing works

Mouse liver repopulation with hepatocytes generated from human fibroblasts

Zhu, S.-Y., Rezvani, M., Harbell, J., Mattis, A. N., Wolfe, A., Benet, L., Willenbring, H., & Ding, S. (2014) · Nature · doi:10.1038/nature13020 · Cited by 266 · see citing works

The POU domain transcription factor Brn-2 is required for the determination of specific neuronal lineages in the hypothalamus of the mouse.Preprint

中井, 茂., Kawano, H., Yudate, T., Nishi, M., Kuno, J., Nagata, A., Jishage, K., Hamada, H., Fujii, H., & Kawamura, K. (1995) · Genes & Development · doi:10.1101/gad.9.24.3109 · Cited by 263 · see citing works

POU-domain proteins: structure and function of developmental regulators

Wegner, M., Drolet, D. W., & Rosenfeld, M. G. (1993) · Current Opinion in Cell Biology · doi:10.1016/0955-0674(93)90015-i · Cited by 258 · see citing works

The Human OCT-4 Isoforms Differ in Their Ability to Confer Self-renewal

Lee, J., Kim, H., Rho, J.-Y., Han, Y., & Kim, J. (2006) · Journal of Biological Chemistry · doi:10.1074/jbc.m603937200 · Cited by 257 · see citing works

Nucleosome–Chd1 structure and implications for chromatin remodelling

Farnung, L., Vos, S. M., Wigge, C., & Cramer, P. (2017) · Nature · doi:10.1038/nature24046 · Cited by 257 · see citing works

Nuclear factor III, a novel sequence-specific DNA-binding protein from HeLa cells stimulating adenovirus DNA replication

Pruijn, G. J. M., van Driel, W., & van der Vliet, P. C. (1986) · Nature · doi:10.1038/322656a0 · Cited by 256 · see citing works

Chromatin Accessibility Dynamics during iPSC Reprogramming

Li, D., Liu, J., Yang, X., Zhou, C., Guo, J., Wu, C., Qin, Y., Guo, L., He, J., Yu, S., et al. (2017) · Cell Stem Cell · doi:10.1016/j.stem.2017.10.012 · Cited by 251 · see citing works

Generation of Endoderm-Derived Human Induced Pluripotent Stem Cells From Primary Hepatocytes

Liu, H., Ye, Z., Kim, Y., Sharkis, S. J., & Jang, Y.-Y. (2010) · Hepatology · doi:10.1002/hep.23626 · Cited by 247 · see citing works

Klf4 Cooperates with Oct3/4 and Sox2 To Activate the Lefty1 Core Promoter in Embryonic Stem Cells

Nakatake, Y., Fukui, N., Iwamatsu, Y., Masui, S., Takahashi, K., Yagi, R., Yagi, K., Miyazaki, J., Matoba, R., Ko, M. S. H., et al. (2006) · Molecular and Cellular Biology · doi:10.1128/mcb.00468-06 · Cited by 247 · see citing works

Allosteric Effects of Pit-1 DNA Sites on Long-Term Repression in Cell Type Specification

Scully, K. M., Jacobson, E. M., Jepsen, K., Lunyak, V. V., Viadiu, H., Carrière, C., Rose, D. W., Hooshmand, F., Aggarwal, A. K., & Rosenfeld, M. G. (2000) · Science · doi:10.1126/science.290.5494.1127 · Cited by 244 · see citing works

Oct‐6: a POU transcription factor expressed in embryonal stem cells and in the developing brain.

Suzuki, N., Rohdewohld, H., Neuman, T., Gruss, P., & Schöler, H. R. (1990) · The EMBO Journal · doi:10.1002/j.1460-2075.1990.tb07585.x · Cited by 239 · see citing works

Mitotic Phosphorylation of the Oct-1 Homeodomain and Regulation of Oct-1 DNA Binding Activity

Segil, N., Roberts, S. B., & Heintz, N. (1991) · Science · doi:10.1126/science.1684878 · Cited by 238 · see citing works

Cooperative Function of POU Proteins and SOX Proteins in Glial Cells

Kuhlbrodt, K., Herbarth, B., Sock, E., Enderich, J., Hermans‐Borgmeyer, I., & Wegner, M. (1998) · Journal of Biological Chemistry · doi:10.1074/jbc.273.26.16050 · Cited by 230 · see citing works

The virtuoso of versatility: POU proteins that flex to fit 1 1Edited by P. Wright

Phillips, K. L., & Luisi, B. F. (2000) · Journal of Molecular Biology · doi:10.1006/jmbi.2000.4107 · Cited by 229 · see citing works

A human protein specific for the immunoglobulin octamer DNA motif contains a functional homeobox domain

Ko, H. S., Fast, P., McBride, W. O., & Staudt, L. M. (1988) · Cell · doi:10.1016/0092-8674(88)90016-5 · Cited by 221 · see citing works

A 100-kD HeLa cell octamer binding protein (OBP100) interacts differently with two separate octamer-related sequences within the SV40 enhancer.Preprint

Sturm, R. A., Baumruker, T., Franza, B. R., & Herr, W. (1987) · Genes & Development · doi:10.1101/gad.1.10.1147 · Cited by 220 · see citing works

Bookmarking by specific and nonspecific binding of FoxA1 pioneer factor to mitotic chromosomesPreprint

Caravaca, J. M., Donahue, G., Becker, J. S., He, X., Charles, V., & Zaret, K. S. (2013) · Genes & Development · doi:10.1101/gad.206458.112 · Cited by 218 · see citing works

Cell-cycle regulation of a human histone H2b gene is mediated by the H2b subtype-specific consensus element.Preprint

Bella, F. L., Sive, H. L., Roeder, R. G., & Heintz, N. (1988) · Genes & Development · doi:10.1101/gad.2.1.32 · Cited by 216 · see citing works

A common octamer motif binding protein is involved in the transcription of U6 snRNA by RNA polymerase III and U2 snRNA by RNA polymerase II

Carbon, P., Murgo, S., Ebel, J., Krol, A., Tebb, G., & Mattaj, I. W. (1987) · Cell · doi:10.1016/0092-8674(87)90011-0 · Cited by 215 · see citing works

Brn-3b: a POU domain gene expressed in a subset of retinal ganglion cells

Xiang, M., Zhou, L., Peng, Y., Eddy, R. L., Shows, T. B., & Nathans, J. (1993) · Neuron · doi:10.1016/0896-6273(93)90079-7 · Cited by 207 · see citing works

Skn-1a (Pou2f3) specifies taste receptor cell lineage

Matsumoto, I., Ohmoto, M., Narukawa, M., Yoshihara, Y., & Abe, K. (2011) · Nature Neuroscience · doi:10.1038/nn.2820 · Cited by 206 · see citing works

Structure of Pit-1 POU domain bound to DNA as a dimer: unexpected arrangement and flexibility.Preprint

Jacobson, E. M., Li, P., León‐Del‐Río, A., Rosenfeld, M. G., & Aggarwal, A. K. (1997) · Genes & Development · doi:10.1101/gad.11.2.198 · Cited by 206 · see citing works

SOX2 Co-Occupies Distal Enhancer Elements with Distinct POU Factors in ESCs and NPCs to Specify Cell State

Lodato, M. A., Ng, C., Wamstad, J. A., Cheng, A. W., Thai, K. K., Fraenkel, E., Jaenisch, R., & Boyer, L. A. (2013) · PLoS Genetics · doi:10.1371/journal.pgen.1003288 · Cited by 196 · see citing works

Oct4 switches partnering from Sox2 to Sox17 to reinterpret the enhancer code and specify endoderm

Aksoy, I., Jauch, R., Chen, J., Dyla, M., Divakar, U., Bogu, G. K., Teo, R., Ng, C. K. L., Herath, W. B., Li-li, S., et al. (2013) · The EMBO Journal · doi:10.1038/emboj.2013.31 · Cited by 194 · see citing works

Reciprocal Regulation of Akt and Oct4 Promotes the Self-Renewal and Survival of Embryonal Carcinoma Cells

Lin, Y., Yang, Y., Li, W., Chen, Q., Li, J., Pan, X., Zhou, L., Liu, C., Chen, C., He, J., et al. (2012) · Molecular Cell · doi:10.1016/j.molcel.2012.08.030 · Cited by 190 · see citing works

Brn-3.0: a POU-domain protein expressed in the sensory, immune, and endocrine systems that functions on elements distinct from known octamer motifs.

Gerrero, M. R., McEvilly, R. J., Turner, E. E., Lin, C. R., O’Connell, S. M., Jenné, K. J., Hobbs, M. V., & Rosenfeld, M. G. (1993) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.90.22.10841 · Cited by 190 · see citing works

Sumoylation of Oct4 Enhances Its Stability, DNA Binding, and Transactivation

Wei, F., Schöler, H. R., & Atchison, M. L. (2007) · Journal of Biological Chemistry · doi:10.1074/jbc.m611041200 · Cited by 180 · see citing works

Human and mouse adipose-derived cells support feeder-independent induction of pluripotent stem cells

Sugii, S., Kida, Y. S., Kawamura, T., Suzuki, J., Vassena, R., Yin, Y.-Q., Lutz, M. K., Berggren, W. T., Belmonte, J. C. I., & Evans, R. M. (2010) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0910172106 · Cited by 179 · see citing works

Small Molecules Enable Cardiac Reprogramming of Mouse Fibroblasts with a Single Factor, Oct4

Wang, H., Cao, N., Spencer, C. I., Nie, B., Ma, T., Xu, T., Zhang, Y., Wang, X., Srivastava, D., & Ding, S. (2014) · Cell Reports · doi:10.1016/j.celrep.2014.01.038 · Cited by 166 · see citing works

Repression of the IgH Enhancer in Teratocarcinoma Cells Associated with a Novel Octamer Factor

Lenardo, M. J., Staudt, L. M., Robbins, P., Kuang, A. A., Mulligan, R. C., & Baltimore, D. (1989) · Science · doi:10.1126/science.2536195 · Cited by 165 · see citing works

Molecular Basis for Synergistic Transcriptional Activation by Oct1 and Sox2 Revealed from the Solution Structure of the 42-kDa Oct1·Sox2·Hoxb1-DNA Ternary Transcription Factor Complex

Williams, D. C., Cai, M., & Clore, G. M. (2004) · Journal of Biological Chemistry · doi:10.1074/jbc.m309790200 · Cited by 164 · see citing works

Astrocytes and glioblastoma cells express novel octamer-DNA binding proteins distinct from the ubiquitous Oct-1 and B cell type Oct-2 proteins

Schreiber, E. H., Harshman, K., Kemler, I., Malipiero, U., Schaffner, W., & Fontana, A. (1990) · Nucleic Acids Research · doi:10.1093/nar/18.18.5495 · Cited by 163 · see citing works

Brn-3.2: A Brn-3-related transcription factor with distinctive central nervous system expression and regulation by retinoic acid

Turner, E. E., Jenné, K. J., & Rosenfeld, M. G. (1994) · Neuron · doi:10.1016/0896-6273(94)90164-3 · Cited by 162 · see citing works

Oct4 links multiple epigenetic pathways to the pluripotency network

Ding, J., Xu, H., Faiola, F., Ma'ayan, A., & Wang, J. (2012) · Cell Research · doi:10.1038/cr.2011.179 · Cited by 162 · see citing works

Conserved POU Binding DNA Sites in the Sox2 Upstream Enhancer Regulate Gene Expression in Embryonic and Neural Stem Cells

Catena, R., Tiveron, C., Ronchi, A. E., Porta, S., Ferri, L., Tatangelo, L., Cavallaro, M., Favaro, R., Ottolenghi, S., Reinbold, R. A., et al. (2004) · Journal of Biological Chemistry · doi:10.1074/jbc.m405514200 · Cited by 160 · see citing works

A unique Oct4 interface is crucial for reprogramming to pluripotency

Esch, D., Vahokoski, J., Groves, M. R., Pogenberg, V., Cojocaru, V., Bruch, H. V., Han, D., Drexler, H. C. A., Araúzo-Bravo, M. J., Ng, C. K. L., et al. (2013) · Nature Cell Biology · doi:10.1038/ncb2680 · Cited by 156 · see citing works

OCT4: Dynamic DNA binding pioneers stem cell pluripotency

Jerabek, S., Merino, F., Schöler, H. R., & Cojocaru, V. (2013) · Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms · doi:10.1016/j.bbagrm.2013.10.001 · Cited by 155 · see citing works

Roles of Sall4 in the generation of pluripotent stem cells from blastocysts and fibroblasts

Tsubooka, N., Ichisaka, T., Okita, K., Takahashi, K., Nakagawa, M., & Yamanaka, S. (2009) · Genes to Cells · doi:10.1111/j.1365-2443.2009.01301.x · Cited by 154 · see citing works

Brain 4: a novel mammalian POU domain transcription factor exhibiting restricted brain‐specific expression.

Mathis, J. M., Simmons, D. M., He, X., Swanson, L. W., & Rosenfeld, M. G. (1992) · The EMBO Journal · doi:10.1002/j.1460-2075.1992.tb05320.x · Cited by 154 · see citing works

Oct transcription factors in development and stem cells: insights and mechanisms

Tantin, D. R. (2013) · Development · doi:10.1242/dev.095927 · Cited by 148 · see citing works

BMPs functionally replace Klf4 and support efficient reprogramming of mouse fibroblasts by Oct4 alone

Chen, J., Liu, J., Yang, J., Chen, Y., Chen, J., Ni, S., Song, H., Zeng, L., Ding, K., & Pei, D. (2010) · Cell Research · doi:10.1038/cr.2010.172 · Cited by 145 · see citing works

Solution structure of the POU-specific DNA-binding domain of Oct-1

Dekker, N., Cox, M., Boelens, R., Verrijzer, C. P., van der Vliet, P. C., & Kaptein, R. (1993) · Nature · doi:10.1038/362852a0 · Cited by 145 · see citing works

Oct4 and Klf4 Reprogram Dermal Papilla Cells into Induced Pluripotent Stem Cells

Tsai, S., Clavel, C., Kim, S., Ang, Y.-S., Grisanti, L., Lee, D., Kelley, K. A., & Rendl, M. (2009) · Stem Cells · doi:10.1002/stem.281 · Cited by 142 · see citing works

Wwp2, an E3 Ubiquitin Ligase That Targets Transcription Factor Oct-4 for Ubiquitination

Xu, H. M., Liao, B., Zhang, Q. J., Wang, B. B., Li, H., Zhong, X. M., SHENG, H. Z., Zhao, Y., Zhao, Y., & Jin, Y. (2004) · Journal of Biological Chemistry · doi:10.1074/jbc.m400516200 · Cited by 142 · see citing works

Synergism with the Coactivator OBF-1 (OCA-B, BOB-1) Is Mediated by a Specific POU Dimer Configuration

Tomilin, A. N., Reményi, A., Lins, K., Bak, H., Leidel, S. A., Vriend, G., Wilmanns, M., & Schöler, H. R. (2000) · Cell · doi:10.1016/s0092-8674(00)00189-6 · Cited by 142 · see citing works

The solution structure of the Oct-1 POU-specific domain reveals a striking similarity to the bacteriophage λ repressor DNA-binding domain

Assa‐Munt, N. (1993) · Cell · doi:10.1016/0092-8674(93)90171-l · Cited by 138 · see citing works

A single amino acid exchange transfers VP16-induced positive control from the Oct-1 to the Oct-2 homeo domain.Preprint

Lai, J. S., Cleary, M. A., & Herr, W. (1992) · Genes & Development · doi:10.1101/gad.6.11.2058 · Cited by 135 · see citing works

Transient acquisition of pluripotency during somatic cell transdifferentiation with iPSC reprogramming factors

Maza, I., Caspi, I., Zviran, A., Chomsky, E., Rais, Y., Viukov, S. V., Geula, S., Buenrostro, J. D., Weinberger, L., Krupalnik, V., et al. (2015) · Nature Biotechnology · doi:10.1038/nbt.3270 · Cited by 133 · see citing works

Octamer transcription factors bind to two different sequence motifs of the immunoglobulin heavy chain promoter.

Kemler, I., Schreiber, E. H., Müller, M. M., Matthias, P., & Schaffner, W. (1989) · The EMBO Journal · doi:10.1002/j.1460-2075.1989.tb03607.x · Cited by 129 · see citing works

Post-Translational Regulation of Oct4 Transcriptional Activity

Saxe, J. P., Tomilin, A. N., Schöler, H. R., Plath, K., & Huang, J. (2009) · PLoS ONE · doi:10.1371/journal.pone.0004467 · Cited by 127 · see citing works

Transient and Permanent Reconfiguration of Chromatin and Transcription Factor Occupancy Drive Reprogramming

Knaupp, A. S., Buckberry, S., Pflueger, J., Lim, S. M., Ford, E., Larcombe, M. R., Rossello, F. J., de Mendoza, A., Alaei, S., Firas, J., et al. (2017) · Cell stem cell · doi:10.1016/j.stem.2017.11.007 · Cited by 127 · see citing works

Differential Dimer Activities of the Transcription Factor Oct-1 by DNA-Induced Interface Swapping

Reményi, A., Tomilin, A. N., Pohl, E., Lins, K., Philippsen, A., Reinbold, R. A., Schöler, H. R., & Wilmanns, M. (2001) · Molecular Cell · doi:10.1016/s1097-2765(01)00336-7 · Cited by 126 · see citing works

Exhaustive Search for Over-represented DNA Sequence Motifs with CisFinder

Sharov, A. A., & Ko, M. S. H. (2009) · DNA Research · doi:10.1093/dnares/dsp014 · Cited by 125 · see citing works

The Oct-2 protein binds cooperatively to adjacent octamer sites.Preprint

LeBowitz, J. H., Clerc, R. G., Brenowitz, M. D., & Sharp, P. A. (1989) · Genes & Development · doi:10.1101/gad.3.10.1625 · Cited by 124 · see citing works

A general mechanism for transcription regulation by Oct1 and Oct4 in response to genotoxic and oxidative stressPreprint

Kang, J., Gemberling, M. P., Nakamura, M., Whitby, F. G., Handa, H., Fairbrother, W. G., & Tantin, D. R. (2009) · Genes & Development · doi:10.1101/gad.1750709 · Cited by 124 · see citing works

Conversion of Human Fibroblasts to Functional Endothelial Cells by Defined Factors

Li, J., Huang, N. F., Zou, J., Laurent, T., Lee, J. C., Okogbaa, J., Cooke, J. P., & Ding, S. (2013) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/atvbaha.112.301167 · Cited by 123 · see citing works

Small Molecules Facilitate the Reprogramming of Mouse Fibroblasts into Pancreatic Lineages

Li, K., Zhu, S., Russ, H. A., Xu, S., Xu, T., Zhang, Y., Ma, T., Hebrok, M., & Ding, S. (2014) · Cell stem cell · doi:10.1016/j.stem.2014.01.006 · Cited by 121 · see citing works

A high-resolution transcriptomic and spatial atlas of cell types in the whole mouse brain

Yao, Z., van Velthoven, C. T. J., Kunst, M., Zhang, M., McMillen, D., Lee, C., Jung, W., Goldy, J., Abdelhak, A., Aitken, M., et al. (2023) · Nature · doi:10.1038/s41586-023-06812-z · Cited by 1,194 · see citing works

Regulation of immune responses by tuft cells

Schneider, C., O’Leary, C. E., & Locksley, R. M. (2019) · Nature reviews. Immunology · doi:10.1038/s41577-019-0176-x · Cited by 260 · see citing works

Tuft Cells—Systemically Dispersed Sensory Epithelia Integrating Immune and Neural Circuitry

O’Leary, C. E., Schneider, C., & Locksley, R. M. (2018) · Annual Review of Immunology · doi:10.1146/annurev-immunol-042718-041505 · Cited by 172 · see citing works

OCA-T1 and OCA-T2 are coactivators of POU2F3 in the tuft cell lineage

Wu, X., He, X., Ipsaro, J. J., Huang, Y., Preall, J. B., Ng, D., Shue, Y. T., Sage, J., Egeblad, M., Joshua‐Tor, L., et al. (2022) · Nature · doi:10.1038/s41586-022-04842-7 · Cited by 92 · see citing works

Pluripotency reprogramming by competent and incompetent POU factors uncovers temporal dependency for Oct4 and Sox2

Malik, V., Glaser, L. V., Zimmer, D., Velychko, S., Weng, M., Holzner, M., Arend, M., Chen, Y., Srivastava, Y., Veerapandian, V., et al. (2019) · Nature Communications · doi:10.1038/s41467-019-11054-7 · Cited by 71 · see citing works

Pou4f1 Defines a Subgroup of Type I Spiral Ganglion Neurons and Is Necessary for Normal Inner Hair Cell Presynaptic Ca2+ Signaling

Sherrill, H. E., Jean, P., Driver, E. C., Sanders, T. R., Fitzgerald, T. S., Moser, T., & Kelley, M. W. (2019) · Journal of Neuroscience · doi:10.1523/jneurosci.2728-18.2019 · Cited by 64 · see citing works

BRN 2, a POU erful driver of melanoma phenotype switching and metastasis

Fane, M. E., Chhabra, Y., Smith, A. G., & Sturm, R. A. (2018) · Pigment Cell & Melanoma Research · doi:10.1111/pcmr.12710 · Cited by 60 · see citing works

Building Principles for Constructing a Mammalian Blastocyst Embryo

Pfeffer, P. (2018) · Biology · doi:10.3390/biology7030041 · Cited by 49 · see citing works

Cortical somatostatin long-range projection neurons and interneurons exhibit divergent developmental trajectories

Fisher, J., Verhagen, M. G., Long, Z., Moissidis, M., Yan, Y., He, C., Wang, J., Micoli, E., Alastruey, C. M., Moors, R., et al. (2023) · Neuron · doi:10.1016/j.neuron.2023.11.013 · Cited by 36 · see citing works

Biological importance of OCT transcription factors in reprogramming and development

Kim, K.-P., Han, D., Kim, J., & Schöler, H. R. (2021) · Experimental & Molecular Medicine · doi:10.1038/s12276-021-00637-4 · Cited by 38 · see citing works

Brn3/POU‐IV‐type POU homeobox genes—Paradigmatic regulators of neuronal identity across phylogeny

Leyva‐Díaz, E., Masoudi, N., Serrano‐Saiz, E., Glenwinkel, L., & Hobert, O. (2020) · Wiley Interdisciplinary Reviews Developmental Biology · doi:10.1002/wdev.374 · Cited by 34 · see citing works

Directed Evolution of Reprogramming Factors by Cell Selection and Sequencing

Veerapandian, V., Ackermann, J. O., Srivastava, Y., Malik, V., Weng, M., Yang, X., & Jauch, R. (2018) · Stem Cell Reports · doi:10.1016/j.stemcr.2018.07.002 · Cited by 29 · see citing works

MAP4K4 controlled transcription factor POUM1 regulates PxABCG1 expression influencing Cry1Ac resistance in Plutella xylostella (L.)

Xu, L., Qin, J., Fu, W., Wang, S., Wu, Q., Zhou, X. J., Crickmore, N., Guo, Z., & Zhang, Y. (2022) · Pesticide Biochemistry and Physiology · doi:10.1016/j.pestbp.2022.105053 · Cited by 28 · see citing works

Induction of OCT2 contributes to regulate the gene expression program in human neutrophils activated via TLR8

Tamassia, N., Bianchetto-Aguilera, F. M., Gasperini, S., Polletti, S., Gardiman, E., Ostuni, R., Natoli, G., & Cassatella, M. A. (2021) · Cell Reports · doi:10.1016/j.celrep.2021.109143 · Cited by 25 · see citing works

Hierarchical reactivation of transcription during mitosis-to-G1 transition by Brn2 and Ascl1 in neural stem cellsPreprint

Soares, M. A. F., Soares, D. S., Teixeira, V., Heskol, A., Bressan, R. B., Pollard, S. M., Oliveira, R. A., & Castro, D. S. (2021) · Genes & Development · doi:10.1101/gad.348174.120 · Cited by 24 · see citing works

OCT2 pre-positioning facilitates cell fate transition and chromatin architecture changes in humoral immunity

Doane, A. S., Chu, C.-S., Giammartino, D. C. D., Rivas, M. A., Hellmuth, J. C., Jiang, Y., Yusufova, N., Alonso, A., Roeder, R. G., Apostolou, E., et al. (2021) · Nature Immunology · doi:10.1038/s41590-021-01025-w · Cited by 20 · see citing works

DNA selection by the master transcription factor PU.1

Terrell, J. R., Taylor, S. J., Schneider, A. L., Lu, Y., Vernon, T. N., Xhani, S., Gumpper, R. H., Luo, M., Wilson, W. D., Steidl, U. G., et al. (2023) · Cell Reports · doi:10.1016/j.celrep.2023.112671 · Cited by 20 · see citing works

The emergence of Sox and POU transcription factors predates the origins of animal stem cells

Gao, Y., Tan, D. S., Girbig, M., Hu, H., Zhou, X., Xie, Q., Yeung, S., Lee, K. S., Ho, S. Y., Cojocaru, V., et al. (2024) · Nature Communications · doi:10.1038/s41467-024-54152-x · Cited by 20 · see citing works

Clinical and Molecular Aspects Associated with Defects in the Transcription Factor POU3F4: A Review

Bernardinelli, E., Huber, F., Roesch, S., & Dossena, S. (2023) · Biomedicines · doi:10.3390/biomedicines11061695 · Cited by 19 · see citing works

Stop codon readthrough alters the activity of a POU/Oct transcription factor during Drosophila development

Zhao, Y., Lindberg, B. G., Esfahani, S. S., Tang, X., Piazza, S., & Engström, Y. (2021) · BMC Biology · doi:10.1186/s12915-021-01106-0 · Cited by 18 · see citing works

A natural transdifferentiation event involving mitosis is empowered by integrating signaling inputs with conserved plasticity factors

Riva, C., Hajdůšková, M., Gally, C., Suman, S. K., Ahier, A., & Jarriault, S. (2022) · Cell Reports · doi:10.1016/j.celrep.2022.111365 · Cited by 18 · see citing works

Maintenance of neuronal identity in C. elegans and beyond: Lessons from transcription and chromatin factors

Destain, H., Prahlad, M., & Kratsios, P. (2023) · Seminars in Cell and Developmental Biology · doi:10.1016/j.semcdb.2023.07.001 · Cited by 18 · see citing works

Directed Evolution of an Enhanced POU Reprogramming Factor for Cell Fate Engineering

Tan, D., Chen, Y.-P., Gao, Y., Bednarz, A., Wei, Y., Malik, V., Ho, D., Weng, M., Ho, S. Y., Srivastava, Y., et al. (2021) · Molecular biology and evolution · doi:10.1093/molbev/msab075 · Cited by 17 · see citing works

Novel inhibitor of OCT1 enhances the sensitivity of human esophageal squamous cell carcinoma cells to antitumor agents

Zou, X.-Z., Zhou, X., Feng, Y., Hao, J., Liang, B., & Jia, M.-W. (2021) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2021.174222 · Cited by 17 · see citing works

Regulation of immune and tissue homeostasis by Drosophila POU factors

Tang, X., & Engström, Y. (2019) · Insect Biochemistry and Molecular Biology · doi:10.1016/j.ibmb.2019.04.003 · Cited by 13 · see citing works

Transcriptional co-repressor CtBP2 orchestrates epithelial-mesenchymal transition through a novel transcriptional holocomplex with OCT1

Ma, Y., Sekiya, M., Kainoh, K., Matsuda, T., IWASAKI, H. O., Osaki, Y., Sugano, Y., Suzuki, H., Takeuchi, Y., Miyamoto, T., et al. (2019) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2019.12.070 · Cited by 13 · see citing works

Structural and biophysical characterization of transcription factor HNF-1A as a tool to study MODY3 diabetes variants

Kind, L., Raasakka, A., Molnes, J., Aukrust, I., Bjørkhaug, L., Njølstad, P. R., Kursula, P., & Arnesen, T. (2022) · Journal of Biological Chemistry · doi:10.1016/j.jbc.2022.101803 · Cited by 13 · see citing works

OLMALINC/OCT4/BMP2 axis enhances osteogenic-like phenotype of renal interstitial fibroblasts to participate in Randall’s plaque formation

Zhu, Z., Huang, F. P., Jiang, Y., Ruan, S., Liu, M., Zhang, Y., Li, Y., Chen, J., Cui, Y., Chen, Z., et al. (2022) · Molecular Medicine · doi:10.1186/s10020-022-00576-4 · Cited by 13 · see citing works

Cancer‐associated missense mutations enhance the pluripotency reprogramming activity of OCT4 and SOX17

Srivastava, Y., Tan, D. S., Malik, V., Weng, M., Javed, A., Cojocaru, V., Wu, G., Veerapandian, V., Cheung, L. W. T., & Jauch, R. (2019) · FEBS Journal · doi:10.1111/febs.15076 · Cited by 12 · see citing works

Novel POU3F4 variants identified in patients with inner ear malformations exhibit aberrant cellular distribution and lack of SLC6A20 transcriptional upregulation

Bernardinelli, E., Roesch, S., Simoni, E., Marino, A., Rasp, G., Astolfi, L., Sarikas, A., & Dossena, S. (2022) · Frontiers in Molecular Neuroscience · doi:10.3389/fnmol.2022.999833 · Cited by 12 · see citing works

The homeodomain of Oct4 is a dimeric binder of methylated CpG elements

Tan, D. S., Cheung, S. L., Gao, Y., Weinbuch, M., Hu, H., Shi, L., Ti, S.-C., Hutchins, A. P., Cojocaru, V., & Jauch, R. (2022) · Nucleic Acids Research · doi:10.1093/nar/gkac1262 · Cited by 11 · see citing works

Unexpected expression of heat-activated transient receptor potential (TRP) channels in winter torpid bats and cold-activated TRP channels in summer active bats

Li, Y., 华东师范大学上海市脑功能基因组学重点实验室, 上., Lv, Q., Zheng, G., Liu, D., Ma, J., He, G., Zhang, L., Zheng, S., Li, H., et al. (2021) · 动物学研究 · doi:10.24272/j.issn.2095-8137.2021.209 · Cited by 10 · see citing works

THOC7-AS1/OCT1/FSTL1 axis promotes EMT and serves as a therapeutic target in cutaneous squamous cell carcinoma

Yu, S., Xu, C., Zhou, S., Li, Y., Feng, W., Zhang, X., Zhong, Y., & Zhang, P. (2024) · Journal of Translational Medicine · doi:10.1186/s12967-024-05116-8 · Cited by 9 · see citing works

Copy number variants suggest different molecular pathways for the pathogenesis of bladder exstrophy

Nordenskjöld, A., Arkani, S., Pettersson, M., Winberg, J., Cao, J., Fossum, M., Anderberg, M., Barker, G., Holmdahl, G., & Lundin, J. (2022) · American Journal of Medical Genetics Part A · doi:10.1002/ajmg.a.63031 · Cited by 9 · see citing works

Bob1 maintains T follicular helper cells for long-term humoral immunity

Yanagi, M., Ikegami, I., Kamekura, R., Sato, T., Sato, T., Kamiya, S., Murayama, K., Jitsukawa, S., Ito, F., Yorozu, A., et al. (2024) · Communications Biology · doi:10.1038/s42003-024-05827-0 · Cited by 9 · see citing works

Transcriptional regulator BOB.1: Molecular mechanisms and emerging role in chronic inflammation and autoimmunity

Yeremenko, N. G., Danger, R., Baeten, D., Tomilin, A. N., & Brouard, S. (2021) · Autoimmunity Reviews · doi:10.1016/j.autrev.2021.102833 · Cited by 9 · see citing works

Cell fate reprogramming through engineering of native transcription factors

Jauch, R. (2018) · Current Opinion in Genetics & Development · doi:10.1016/j.gde.2018.05.013 · Cited by 8 · see citing works

Research progress of the transcription factor Brn4 (Review)

Wu, Y., Zhang, X., Wang, J., Jin, G., & Zhang, X. (2020) · Molecular Medicine Reports · doi:10.3892/mmr.2020.11818 · Cited by 8 · see citing works

Exploring the Heterogeneity of Non-Syndromic Hearing Loss: A Comprehensive Review of Implicated Genes and the Role of Whole Exome Sequencing

Barrak, M. M., Bonyadi, M. J., Hami, H. J., Ali, M. D. A., Muttair, R. Y., & Abd, R. A. (2023) · University of Thi-Qar Journal of Science · doi:10.32792/utq/utjsci/v10i2.1143 · Cited by 8 · see citing works

Establishment of resveratrol and its derivatives as neuroprotectant against monocrotophos-induced alteration in NIPBL and POU4F1 protein through molecular docking studies

Yadav, R., & Srivastava, P. (2019) · Environmental Science and Pollution Research · doi:10.1007/s11356-019-06806-3 · Cited by 8 · see citing works

Identification of POU4F1 as a novel prognostic biomarker and therapeutic target in esophageal squamous cell carcinoma

Li, N., Chen, S., Wang, X., Zhang, B., Zeng, B., Sun, C., Zheng, K., Chen, Q., & Wang, S. (2024) · Cancer Cell International · doi:10.1186/s12935-024-03471-6 · Cited by 7 · see citing works

Mechanisms of OCT4 on 3,5,3’-Tri-iodothyronine and FSH-induced Granulosa Cell Development in Female Mice

Wang, Q., Yao, Y., Ma, X., Fu, B., Li, N., & Zhang, C. (2021) · Endocrinology · doi:10.1210/endocr/bqab183 · Cited by 7 · see citing works

Single-nucleus multiomics reveals the gene regulatory networks underlying sex determination of murine primordial germ cells

Alexander, A. K., Rodriguez, K. F., Chen, Y., Amato, C. M., Estermann, M. A., Nicol, B., Xu, X., & Yao, H. H. (2025) · eLife · doi:10.7554/elife.96591.3 · Cited by 6 · see citing works

POU domain motif3 (Pdm3) induces wingless (wg) transcription and is essential for development of larval neuromuscular junctions in Drosophila

Kim, Y. S., & Cho, K.-O. (2020) · Scientific Reports · doi:10.1038/s41598-020-57425-9 · Cited by 6 · see citing works

Integrating transcriptomics and genomics to identify fibroblast growth factor/receptor candidate genes for non‐syndromic orofacial cleft in Chinese

Ge, B., Lin, Y., Shi, B., & Jia, Z. (2023) · Archives of Oral Biology · doi:10.1016/j.archoralbio.2023.105750 · Cited by 5 · see citing works

Lama2 And Samsn1 Mediate the Effects of Brn4 on Hippocampal Neural Stem Cell Proliferation and Differentiation

Zhang, L., Zhang, X., Ji, R., Ji, Y., Wu, Y., Ding, X., Shang, Z., Liu, X., Li, W., Guo, J., et al. (2023) · Stem Cells International · doi:10.1155/2023/7284986 · Cited by 4 · see citing works

The late-evolving salmon and trout join the GnRH1 club

von Schalburg, K. R., Gowen, B. E., Christensen, K. A., Ignatz, E. H., Hall, J. R., & Rise, M. L. (2023) · Histochemistry and Cell Biology · doi:10.1007/s00418-023-02227-z · Cited by 4 · see citing works

Osmosensitive transcription factors in the prolactin cell of a euryhaline teleost

Malintha, G. H. T., Celino‐Brady, F. T., Stoytcheva, Z., & Seale, A. P. (2022) · Comparative Biochemistry and Physiology Part A Molecular & Integrative Physiology · doi:10.1016/j.cbpa.2022.111356 · Cited by 4 · see citing works

Retinoic Acid and POU Genes in Developing Amphioxus: A Focus on Neural Development

Bozzo, M., Bellitto, D., Amaroli, A., Ferrando, S., Schubert, M., & Candiani, S. (2023) · Cells · doi:10.3390/cells12040614 · Cited by 4 · see citing works

FXR1 stabilizes SNORD63 to regulate blood-tumor barrier permeability through SNORD63 mediated 2’-O-methylation of POU6F1

Liang, C.-C., Zhai, B., Deng, W., Niu, B., Ma, J., Yao, Y., Yang, L., Liu, Y., Liu, X., & Wang, P. (2024) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2024.130642 · Cited by 4 · see citing works

Unexpected High Levels of BRN2/POU3F2 Expression in Human Dermal Melanocytic Nevi

Chitsazan, A., Lambie, D., Ferguson, B., Handoko, H. Y., Gabrielli, B. G., Walker, G. J., & Boyle, G. M. (2019) · Journal of Investigative Dermatology · doi:10.1016/j.jid.2019.12.007 · Cited by 4 · see citing works

Neural Transcription Factors in Disease Progression

Thaper, D., Vahid, S., & Zoubeidi, A. (2019) · Advances in experimental medicine and biology · doi:10.1007/978-3-030-32656-2_19 · Cited by 4 · see citing works

Single-nucleus multiomics reveals the gene-regulatory networks underlying sex determination of murine primordial germ cellsPreprint

Alexander, A. K., Rodriguez, K. F., Chen, Y., Amato, C. M., Estermann, M. A., Xu, X. M., & Yao, H. H. (2024) · eLife · doi:10.7554/elife.96591.1 · Cited by 4 · see citing works

Single-nucleus multiomics reveals the gene regulatory networks underlying sex determination of murine primordial germ cellsPreprint

Alexander, A. K., Rodriguez, K. F., Chen, Y., Amato, C. M., Estermann, M. A., Nicol, B., Xu, X., & Yao, H. H. (2024) · eLife · doi:10.7554/elife.96591 · Cited by 4 · see citing works

A cycling, progenitor-like cell population at the base of atypical teratoid rhabdoid tumor subtype differentiation trajectories

Blanco-Carmona, E., Paassen, I., He, J., DeMartino, J., Büllesbach, A., Anderson, N., Buhl, J. L., Federico, A., Mauermann, M., Brok, M. O., et al. (2025) · Neuro-Oncology · doi:10.1093/neuonc/noaf179 · Cited by 3 · see citing works

In Silico Estimation of the Abundance and Phylogenetic Significance of the Composite Oct4-Sox2 Binding Motifs within a Wide Range of Species

Kulyyassov, A., & Kalendar, R. N. (2020) · Data · doi:10.3390/data5040111 · Cited by 3 · see citing works

Discovery and characterization of a first-in-field transcription factor BRN2 inhibitor for the treatment of neuroendocrine prostate cancerPreprint

Thaper, D., Munuganti, R. S. N., Aguda, A. H., Kim, S., Ku, S., Sivak, O., Kumar, S., Vahid, S., Ganguli, D., Beltran, H., et al. (2022) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2022.05.04.490172 · Cited by 3 · see citing works

Transcriptional Coactivator BOB1 (OBF1, OCA-B) Modulates the Specificity of DNA Recognition by the POU-Domain Factors OCT1 and OCT2 in a Monomeric Configuration

Nazarov, I. B., Zilov, D., Gordeev, M. N., Potapenko, E. V., Yeremenko, N. G., & Tomilin, A. N. (2024) · Biomolecules · doi:10.3390/biom14010123 · Cited by 1 · see citing works

Основні транскрипційні фактори, які беруть участь у функціонуванні стовбурових клітин. Особливості їх активації та експресії в β-клітинах підшлункової залози (Частина1)

Tronko, M. D., Pushkarev, V. M., Kovzun, О. I., SOKOLOVA, L. K., & PUSHKAREV, V. V. (2022) · Endokrynologia · doi:10.31793/1680-1466.2022.27-4.325 · Cited by 1 · see citing works

Differential usage of two, distinct DNA-binding domains regulates tissue-specific occupancy of the pioneer factor ZeldaPreprint

Torres‐Zelada, E. F., Komori, H., Liu, H., Larson, E. D., Yang, A. W. H., Fitzpatrick, Z. A., Hughes, T. R., Rushlow, C. A., Lee, C., & Harrison, M. M. (2025) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2025.10.06.680768 · Cited by 1 · see citing works

Structural and biophysical characterization of HNF-1A as a tool to study MODY3 diabetes variantsPreprint

Kind, L., Raasakka, A., Molnes, J., Aukrust, I., Bjørkhaug, L., Njølstad, P. R., Kursula, P., & Arnesen, T. (2021) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2021.12.20.473529

Dissecting synaptic mechanisms of sound encoding in the mouse cochlea

Jean, P. (2019) · doi:10.53846/goediss-7450

Single-nucleus multiomics reveals the gene-regulatory networks underlying sex determination of murine primordial germ cellsPreprint

Alexander, A. K., Rodriguez, K. F., Chen, Y., Amato, C. M., Estermann, M. A., Nicol, B., Xu, X., & Yao, H. H. (2025) · eLife · doi:10.7554/elife.96591.2

Coupled Heterogeneity to Dimeric Site-Specific Binding by the POU-Family Transcription Factor OCT2

Terrell, J. R., & Poon, G. M. K. (2025) · The Journal of Physical Chemistry B · doi:10.1021/acs.jpcb.4c07071

Early epigenetic priming of regeneration studied with a novel transgenic epigenetic reporterPreprint

Khor, J. M., Cisneros, I., Marvel, M., Gore, A. V., Taimatsu, K., Margolin, G., Castranova, D., Goldstein, A. E., Dale, R., & Weinstein, B. M. (2025) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2025.04.21.649771

Additional file 13 of Stop codon readthrough alters the activity of a POU/Oct transcription factor during Drosophila development

Zhao, Y., Lindberg, B. G., Esfahani, S. S., Tang, X., Piazza, S., & Engström, Y. (2021) · Figshare · doi:10.6084/m9.figshare.16569856

Additional file 2 of Stop codon readthrough alters the activity of a POU/Oct transcription factor during Drosophila development

Zhao, Y., Lindberg, B. G., Esfahani, S. S., Tang, X., Piazza, S., & Engström, Y. (2021) · Figshare · doi:10.6084/m9.figshare.16569874

Additional file 17 of Stop codon readthrough alters the activity of a POU/Oct transcription factor during Drosophila development

Zhao, Y., Lindberg, B. G., Esfahani, S. S., Tang, X., Piazza, S., & Engström, Y. (2021) · Figshare · doi:10.6084/m9.figshare.16569868

Additional file 1 of THOC7-AS1/OCT1/FSTL1 axis promotes EMT and serves as a therapeutic target in cutaneous squamous cell carcinoma

Yu, S., Cui, X., Zhou, S., Li, Y., Feng, W., Zhang, X., Zhong, Y., & Zhang, P. (2024) · Figshare · doi:10.6084/m9.figshare.26705304

Additional file 5 of THOC7-AS1/OCT1/FSTL1 axis promotes EMT and serves as a therapeutic target in cutaneous squamous cell carcinoma

Yu, S., Cui, X., Zhou, S., Li, Y., Feng, W., Zhang, X., Zhong, Y., & Zhang, P. (2024) · Figshare · doi:10.6084/m9.figshare.26705316

Additional file 2 of OLMALINC/OCT4/BMP2 axis enhances osteogenic-like phenotype of renal interstitial fibroblasts to participate in Randall’s plaque formation

Zhu, Z., Huang, F., Jiang, Y., Ruan, S., Liu, M., Zhang, Y., Li, Y., Chen, J., Cui, Y., Chen, Z., et al. (2023) · Figshare · doi:10.6084/m9.figshare.22598563

Additional file 11 of Stop codon readthrough alters the activity of a POU/Oct transcription factor during Drosophila development

Zhao, Y., Lindberg, B. G., Esfahani, S. S., Tang, X., Piazza, S., & Engström, Y. (2021) · Figshare · doi:10.6084/m9.figshare.16569850

Additional file 10 of Stop codon readthrough alters the activity of a POU/Oct transcription factor during Drosophila development

Zhao, Y., Lindberg, B. G., Esfahani, S. S., Tang, X., Piazza, S., & Engström, Y. (2021) · Figshare · doi:10.6084/m9.figshare.16569844

Additional file 14 of Stop codon readthrough alters the activity of a POU/Oct transcription factor during Drosophila development

Zhao, Y., Lindberg, B. G., Esfahani, S. S., Tang, X., Piazza, S., & Engström, Y. (2021) · Figshare · doi:10.6084/m9.figshare.16569859

Additional file 4 of THOC7-AS1/OCT1/FSTL1 axis promotes EMT and serves as a therapeutic target in cutaneous squamous cell carcinoma

Yu, S., Cui, X., Zhou, S., Li, Y., Feng, W., Zhang, X., Zhong, Y., & Zhang, P. (2024) · Figshare · doi:10.6084/m9.figshare.26705313

Additional file 3 of Stop codon readthrough alters the activity of a POU/Oct transcription factor during Drosophila development

Zhao, Y., Lindberg, B. G., Esfahani, S. S., Tang, X., Piazza, S., & Engström, Y. (2021) · Figshare · doi:10.6084/m9.figshare.16569877

Additional file 1 of Stop codon readthrough alters the activity of a POU/Oct transcription factor during Drosophila development

Zhao, Y., Lindberg, B. G., Esfahani, S. S., Tang, X., Piazza, S., & Engström, Y. (2021) · Figshare · doi:10.6084/m9.figshare.16569871

Additional file 15 of Stop codon readthrough alters the activity of a POU/Oct transcription factor during Drosophila development

Zhao, Y., Lindberg, B. G., Esfahani, S. S., Tang, X., Piazza, S., & Engström, Y. (2021) · Figshare · doi:10.6084/m9.figshare.16569862

Additional file 3 of OLMALINC/OCT4/BMP2 axis enhances osteogenic-like phenotype of renal interstitial fibroblasts to participate in Randall’s plaque formation

Zhu, Z., Huang, F., Jiang, Y., Ruan, S., Liu, M., Zhang, Y., Li, Y., Chen, J., Cui, Y., Chen, Z., et al. (2023) · Figshare · doi:10.6084/m9.figshare.22598566

Additional file 4 of OLMALINC/OCT4/BMP2 axis enhances osteogenic-like phenotype of renal interstitial fibroblasts to participate in Randall’s plaque formation

Zhu, Z., Huang, F., Jiang, Y., Ruan, S., Liu, M., Zhang, Y., Li, Y., Chen, J., Cui, Y., Chen, Z., et al. (2023) · Figshare · doi:10.6084/m9.figshare.22598569

Additional file 5 of OLMALINC/OCT4/BMP2 axis enhances osteogenic-like phenotype of renal interstitial fibroblasts to participate in Randall’s plaque formation

Zhu, Z., Huang, F., Jiang, Y., Ruan, S., Liu, M., Zhang, Y., Li, Y., Chen, J., Cui, Y., Chen, Z., et al. (2023) · Figshare · doi:10.6084/m9.figshare.22598572

Additional file 3 of THOC7-AS1/OCT1/FSTL1 axis promotes EMT and serves as a therapeutic target in cutaneous squamous cell carcinoma

Yu, S., Cui, X., Zhou, S., Li, Y., Feng, W., Zhang, X., Zhong, Y., & Zhang, P. (2024) · Figshare · doi:10.6084/m9.figshare.26705310

Additional file 16 of Stop codon readthrough alters the activity of a POU/Oct transcription factor during Drosophila development

Zhao, Y., Lindberg, B. G., Esfahani, S. S., Tang, X., Piazza, S., & Engström, Y. (2021) · Figshare · doi:10.6084/m9.figshare.16569865

Additional file 2 of THOC7-AS1/OCT1/FSTL1 axis promotes EMT and serves as a therapeutic target in cutaneous squamous cell carcinoma

Yu, S., Cui, X., Zhou, S., Li, Y., Feng, W., Zhang, X., Zhong, Y., & Zhang, P. (2024) · Figshare · doi:10.6084/m9.figshare.26705307

Additional file 7 of THOC7-AS1/OCT1/FSTL1 axis promotes EMT and serves as a therapeutic target in cutaneous squamous cell carcinoma

Yu, S., Cui, X., Zhou, S., Li, Y., Feng, W., Zhang, X., Zhong, Y., & Zhang, P. (2024) · Figshare · doi:10.6084/m9.figshare.26705322

Additional file 1 of OLMALINC/OCT4/BMP2 axis enhances osteogenic-like phenotype of renal interstitial fibroblasts to participate in Randall’s plaque formation

Zhu, Z., Huang, F., Jiang, Y., Ruan, S., Liu, M., Zhang, Y., Li, Y., Chen, J., Cui, Y., Chen, Z., et al. (2023) · Figshare · doi:10.6084/m9.figshare.22598560

Additional file 8 of Stop codon readthrough alters the activity of a POU/Oct transcription factor during Drosophila development

Zhao, Y., Lindberg, B. G., Esfahani, S. S., Tang, X., Piazza, S., & Engström, Y. (2021) · Figshare · doi:10.6084/m9.figshare.16569892

Additional file 12 of Stop codon readthrough alters the activity of a POU/Oct transcription factor during Drosophila development

Zhao, Y., Lindberg, B. G., Esfahani, S. S., Tang, X., Piazza, S., & Engström, Y. (2021) · Figshare · doi:10.6084/m9.figshare.16569853

Additional file 4 of Stop codon readthrough alters the activity of a POU/Oct transcription factor during Drosophila development

Zhao, Y., Lindberg, B. G., Esfahani, S. S., Tang, X., Piazza, S., & Engström, Y. (2021) · Figshare · doi:10.6084/m9.figshare.16569880

Additional file 6 of THOC7-AS1/OCT1/FSTL1 axis promotes EMT and serves as a therapeutic target in cutaneous squamous cell carcinoma

Yu, S., Cui, X., Zhou, S., Li, Y., Feng, W., Zhang, X., Zhong, Y., & Zhang, P. (2024) · Figshare · doi:10.6084/m9.figshare.26705319

Functional Properties of POU1F1 Mutants in the Transcriptional Regulation of the Thyrotropin β Gene Compared with the Prolactin Gene

Kawauchi, Y., Sasaki, S., Matsushita, A., Nakamura, H. M., Yamashita, M., Kakizawa, K., Ohba, K., Tsuriya, D., Tanaka, T., & Suda, T. (2025) · International Journal of Molecular Sciences · doi:10.3390/ijms27010119

Primate lineage specification requires suppression of Alu hypereditingPreprint

Park, E. J., Cui, Y., Levin-Ferreyra, F., Soriano, V. L., Wu, H., Lupión-Garcia, N., Sands, C. M., Pessina, P., Guerra, M. C., Botas, J., et al. (2026) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.64898/2026.01.14.699349

Generation of the induced pluripotent stem cell line ISMMSi061-A from a patient with ataxia, intention tremor, and hypotonia syndrome, childhood-onset

Liu, N. N., Hu, R., Hubbard, S., Salemi, S. E., Baljinnyam, E., Pradhan, P., Smith, G., Webb, B. D., & Marro, S. G. (2026) · Stem Cell Research · doi:10.1016/j.scr.2026.103938

Identification and Functional Characterization of a Novel POU3F4 Frameshift Mutation in a Chinese Family

Fan, S., Guan, Y., Xiang, M., Hongzhe, Y., Zhang, T., Fu, J., Fei, J., Xiao, Y., & Wang, Y. (2026) · Life · doi:10.3390/life16060868

Molecular basis of UV lesion binding and repair inhibition by ETS-family transcription factors

Sivapragasam, S., Terrell, J. R., van der Vaart, A., Germann, M. W., Laughery, M. F., Everly, M. E., Adhikari, S. P., Hrdlicka, P. J., Wyrick, J. J., & Poon, G. M. K. (2026) · Nucleic Acids Research · doi:10.1093/nar/gkag711 · Cited by 1 · see citing works

Gene regulatory innovations from transposable elements in primate cerebellum development

Yamada, T., Sepp, M., Sarropoulos, I., & Kaessmann, H. (2026) · Nature Communications · doi:10.1038/s41467-026-75700-7

BRN2 in lineage plasticity: a prostate cancer-focused perspective

Seilani, F., Peng, J., Wu, M., Farahani, M. E., Wang, X., Akinyemi, A. O., & Liu, X. (2026) · Endocrinology · doi:10.1210/endocr/bqag102

OCT4: Dynamic DNA binding pioneers stem cell pluripotency

Jerabek, S., Merino, F., Schöler, H. R., & Cojocaru, V. (2013) · Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms · doi:10.1016/j.bbagrm.2013.10.001 · Cited by 155 · see citing works

Regulation of transcription and cell identity by POU domain proteins

Ruvkun, G., & Finney, M. (1991) · Cell · doi:10.1016/0092-8674(91)90227-p · Cited by 231 · see citing works

POU Domain Factors in Neural Development

Schonemann, M. D., Ryan, A. K., Erkman, L., McEvilly, R. J., Bermingham, J. R., & Rosenfeld, M. G. (1998) · Advances in experimental medicine and biology · doi:10.1007/978-1-4615-4871-3_4 · Cited by 59 · see citing works

A unique Oct4 interface is crucial for reprogramming to pluripotency

Esch, D., Vahokoski, J., Groves, M. R., Pogenberg, V., Cojocaru, V., Bruch, H. V., Han, D., Drexler, H. C. A., Araúzo-Bravo, M. J., Ng, C. K. L., et al. (2013) · Nature Cell Biology · doi:10.1038/ncb2680 · Cited by 156 · see citing works

Identification of Novel DNA Binding Sites Recognized by the Transcription Factor mPOU (POU6F1)

Wey, E., & Schäfer, B. W. (1996) · Biochemical and Biophysical Research Communications · doi:10.1006/bbrc.1996.0395 · Cited by 13 · see citing works