GLP-1 receptor agonist promotes brown remodelling in mouse white adipose tissue through SIRT1

Brown Adipose Tissue: Function and Physiological Significance

CANNON, B., & NEDERGAARD, J. (2004) · Physiological Reviews · doi:10.1152/physrev.00015.2003 · Cited by 6,433 · see citing works

Small molecule activators of SIRT1 as therapeutics for the treatment of type 2 diabetes

Milne, J. C., Lambert, P. D., Schenk, S., Carney, D. P., Smith, J. J., Gagne, D. J., Jin, L., Boss, O., Perni, R. B., Vu, C. B., et al. (2007) · Nature · doi:10.1038/nature06261 · Cited by 1,707 · see citing works

Effects of exenatide (exendin-4) on glycemic control and weight over 30 weeks in metformin-treated patients with type 2 diabetes

DeFronzo, R. A., Ratner, R. E., Han, J., Kim, D. D., Fineman, M. S., & Baron, A. D. (2005) · Diabetes Care · doi:10.2337/diacare.28.5.1092 · Cited by 1,559 · see citing works

Adipose tissue browning and metabolic health

Bartelt, A., & Heeren, J. (2014) · Nature Reviews Endocrinology · doi:10.1038/nrendo.2013.204 · Cited by 1,177 · see citing works

Effects of liraglutide in the treatment of obesity: A randomised, double-blind, placebo-controlled study

Astrup, A., Rössner, S., Van Gaal, L., Rissanen, A., Niskanen, L., Al Hakim, M., Madsen, J., Rasmussen, M. F., & Lean, M. E. (2009) · The Lancet · doi:10.1016/s0140-6736(09)61375-1 · Cited by 1,163 · see citing works

Developmental defects and p53 hyperacetylation in Sir2 homolog (SIRT1)-deficient mice

Cheng, H.-L., Mostoslavsky, R., Saito, S., Manis, J. P., Gu, Y., Patel, P., Bronson, R., Appella, E., Alt, F. W., & Chua, K. F. (2003) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1934713100 · Cited by 1,095 · see citing works

Adaptive thermogenesis in adipocytes: Is beige the new brown?

Wu, J., Cohen, P., & Spiegelman, B. M. (2013) · Genes & Development · doi:10.1101/gad.211649.112 · Cited by 828 · see citing works

Brown Remodeling of White Adipose Tissue by SirT1-Dependent Deacetylation of Pparγ

Qiang, L., Wang, L., Kon, N., Zhao, W., Lee, S., Zhang, Y., ROSENBAUM, M. S., Zhao, Y., Gu, W. J., Farmer, S. R., et al. (2012) · Cell · doi:10.1016/j.cell.2012.06.027 · Cited by 802 · see citing works

The emergence of cold-induced brown adipocytes in mouse white fat depots is determined predominantly by white to brown adipocyte transdifferentiation

Barbatelli, G., Murano, I., Madsen, L., Hao, Q., Jimenez, M., Kristiansen, K., Giacobino, J., Matteis, R. D., & Cinti, S. (2010) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.00600.2009 · Cited by 751 · see citing works

Specific SIRT1 Activation Mimics Low Energy Levels and Protects against Diet-Induced Metabolic Disorders by Enhancing Fat Oxidation

Feige, J. N., Lagouge, M., Canto, C., Strehle, A., Houten, S. M., Milne, J. C., Lambert, P. D., Mataki, C., Elliott, P. J., & Auwerx, J. (2008) · Cell Metabolism · doi:10.1016/j.cmet.2008.08.017 · Cited by 719 · see citing works

AMP-activated protein kinase-deficient mice are resistant to the metabolic effects of resveratrol

Um, J.-H., Park, S.-J., Kang, H., Yang, S., Foretz, M., McBurney, M. W., Kim, M. K., Viollet, B., & Chung, J. H. (2010) · Diabetes · doi:10.2337/db09-0482 · Cited by 647 · see citing works

Mitochondrial remodeling in adipose tissue associated with obesity and treatment with rosiglitazone.

Wilson-Fritch, L., Nicoloro, S., Chouinard, M., Lazar, M. A., Chui, P. C., Leszyk, J., Straubhaar, J., Czech, M. P., & Corvera, S. (2004) · Journal of Clinical Investigation · doi:10.1172/jci21752 · Cited by 616 · see citing works

GLP-1 agonism stimulates brown adipose tissue thermogenesis and browning through hypothalamic AMPK

Beiroa, D., Imbernon, M., Gallego, R., Senra, A., Herranz, D., Villarroya, F., Serrano, M., Fernø, J., Salvador, J., Escalada, J., et al. (2014) · Diabetes · doi:10.2337/db14-0302 · Cited by 602 · see citing works

GLP-1 Receptor Activation Modulates Appetite- and Reward-Related Brain Areas in Humans

van Bloemendaal, L., IJzerman, R. G., ten Kulve, J. S., Barkhof, F., Konrad, R. J., Drent, M. L., Veltman, D. J., & Diamant, M. (2014) · Diabetes · doi:10.2337/db14-0849 · Cited by 427 · see citing works

Dissecting adipose tissue lipolysis: molecular regulation and implications for metabolic disease

Nielsen, T. S., Jessen, N., Jørgensen, J. O. L., Møller, N., & Lund, S. A. (2014) · Journal of Molecular Endocrinology · doi:10.1530/jme-13-0277 · Cited by 380 · see citing works

Peripheral and central GLP-1 receptor populations mediate the anorectic effects of peripherally administered GLP-1 receptor agonists, liraglutide and exendin-4

Kanoski, S. E., Fortin, S. M., Arnold, M., Grill, H. J., & Hayes, M. R. (2011) · Endocrinology · doi:10.1210/en.2011-0174 · Cited by 347 · see citing works

Effects of glucagon-like peptide 1 on appetite and body weight: focus on the CNS

van Bloemendaal, L., ten Kulve, J. S., la Fleur, S. E., Ijzerman, R. G., & Diamant, M. (2014) · Journal of Endocrinology · doi:10.1530/joe-13-0414 · Cited by 312 · see citing works

Weight loss with liraglutide, a once‐daily human glucagon‐like peptide‐1 analogue for type 2 diabetes treatment as monotherapy or added to metformin, is primarily as a result of a reduction in fat tissue

Jendle, J., Nauck, M. A., Matthews, D. R., Frid, A., Hermansen, K., Düring, M., Zdravkovic, M., Strauss, B. J., Garber, A. J., & Groups, O. B. O. T. L. A. L. S. (2009) · Diabetes, Obesity and Metabolism · doi:10.1111/j.1463-1326.2009.01158.x · Cited by 312 · see citing works

Adipocyte Mitochondrial Function Is Reduced in Human Obesity Independent of Fat Cell Size

Yin, X. L., Lanza, I. R., Swain, J. M., Sarr, M. G., Nair, K. S., & Jensen, M. D. (2013) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2013-3042 · Cited by 226 · see citing works

Lack of SIRT1 (Mammalian Sirtuin 1) Activity Leads to Liver Steatosis in the SIRT1+/− Mice: A Role of Lipid Mobilization and Inflammation

Xu, F. L., Gao, Z., Zhang, J., Rivera, C. A., Yin, J., Weng, J., & Ye, J. (2010) · Endocrinology · doi:10.1210/en.2009-1013 · Cited by 221 · see citing works

Prolonged AICAR-induced AMP-kinase activation promotes energy dissipation in white adipocytes: novel mechanisms integrating HSL and ATGL

Gaidhu, M. P., Fediuc, S., Anthony, N. M., So, M., Mirpourian, M., Perry, R. L. S., & Ceddia, R. B. (2008) · Journal of Lipid Research · doi:10.1194/jlr.m800480-jlr200 · Cited by 200 · see citing works

Glucagon-like peptide-1 inhibits gastropancreatic function by inhibiting central parasympathetic outflow

Wettergren, A., Wøjdemann, M., & Holst, J. J. (1998) · American Journal of Physiology-Gastrointestinal and Liver Physiology · doi:10.1152/ajpgi.1998.275.5.g984 · Cited by 194 · see citing works

Direct control of peripheral lipid deposition by CNS GLP-1 receptor signaling is mediated by the sympathetic nervous system and blunted in diet-induced obesity

Nogueiras, R., Pérez-Tilve, D., Veyrat-Durebex, C., Morgan, D. A., Varela, L., Haynes, W. G., Patterson, J. T., Disse, E., Pfluger, P. T., López, M., et al. (2009) · The Journal of Neuroscience · doi:10.1523/jneurosci.5977-08.2009 · Cited by 182 · see citing works

SIRT1 controls lipolysis in adipocytes via FOXO1-mediated expression of ATGL

Chakrabarti, P., English, T., Karki, S., Qiang, L., Tao, R., Kim, J., Luo, Z., Farmer, S. R., & Kandror, K. V. (2011) · Journal of Lipid Research · doi:10.1194/jlr.m014647 · Cited by 179 · see citing works

Study of the potential association of adipose tissue GLP-1 receptor with obesity and insulin resistance

Vendrell, J., El Bekay, R., Peral, B., García-Fuentes, E., Megia, A., Macias-Gonzalez, M., Real, J. F., Jimenez-Gomez, Y., Escoté, X., Pachón, G., et al. (2011) · Endocrinology · doi:10.1210/en.2011-1070 · Cited by 173 · see citing works

Activation of the GLP-1 Receptors in the Nucleus of the Solitary Tract Reduces Food Reward Behavior and Targets the Mesolimbic System

Richard, J. E., Anderberg, R. H., Göteson, A., Gribble, F. M., Reimann, F., & Skibicka, K. P. (2015) · PLOS ONE · doi:10.1371/journal.pone.0119034 · Cited by 168 · see citing works

Resveratrol increases brown adipose tissue thermogenesis markers by increasing SIRT1 and energy expenditure and decreasing fat accumulation in adipose tissue of mice fed a standard diet

Andrade, J. M. O., Frade, A. C. M., Guimarães, J. B., Freitas, K. M., Lopes, M. T. P., Guimarães, A. L. S., de Paula, A. M. B., Coimbra, C. C., & Santos, S. H. S. (2014) · European Journal of Nutrition · doi:10.1007/s00394-014-0655-6 · Cited by 168 · see citing works

Central GLP-1 receptor signalling accelerates plasma clearance of triacylglycerol and glucose by activating brown adipose tissue in mice

Kooijman, S., Wang, Y., Parlevliet, E. T., Boon, M. R., Edelschaap, D., Snaterse, G., Pijl, H., Romijn, J. A., & Rensen, P. C. N. (2015) · Diabetologia · doi:10.1007/s00125-015-3727-0 · Cited by 140 · see citing works

Diabetes Risk Among Overweight and Obese Metabolically Healthy Young Adults

Twig, G., Afek, A. B., Derazne, E., Tzur, D., Cukierman‐Yaffe, T., Gerstein, H. C., & Tirosh, A. (2014) · Diabetes Care · doi:10.2337/dc14-0869 · Cited by 116 · see citing works

SIRT1 Mediates the Effect of GLP-1 Receptor Agonist Exenatide on Ameliorating Hepatic Steatosis

Xu, F., Li, Z., Zheng, X., Liu, H., Liang, H., Xu, H., Chen, Z., Zeng, K., & Weng, J. (2014) · Diabetes · doi:10.2337/db14-0263 · Cited by 114 · see citing works

Dipeptidyl-Peptidase-IV Inhibition Augments Postprandial Lipid Mobilization and Oxidation in Type 2 Diabetic Patients

Boschmann, M., Engeli, S., Dobberstein, K., Budziarek, P., Strauss, A., Boehnke, J., Sweep, F. C. G. J., Luft, F. C., He, Y., Foley, J. E., et al. (2008) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2008-1400 · Cited by 110 · see citing works

The role of AMP-activated protein kinase in regulating white adipose tissue metabolism

Ceddia, R. B. (2012) · Molecular and Cellular Endocrinology · doi:10.1016/j.mce.2012.06.014 · Cited by 105 · see citing works

Resveratrol enhances fatty acid oxidation capacity and reduces resistin and Retinol-Binding Protein 4 expression in white adipocytes

Mercader, J., Palou, A., & Bonet, M. L. (2010) · The Journal of Nutritional Biochemistry · doi:10.1016/j.jnutbio.2010.07.007 · Cited by 96 · see citing works

Action of Glucagon and Glucagon-Like Peptide-1-(7-36) Amide on Lipolysis in Human Subcutaneous Adipose Tissue and Skeletal Musclein Vivo1

Bertin, É., Arner, P., Bolinder, J., & Toft, E. (2001) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.86.3.7330 · Cited by 83 · see citing works

Effects of exenatide, insulin, and pioglitazone on liver fat content and body fat distributions in drug-naive subjects with type 2 diabetes

Bi, Y., Zhang, B., Xu, W., Yang, H., Feng, W., Li, C., Tong, G., Li, M., Wang, X., Shen, S., et al. (2014) · Acta Diabetologica · doi:10.1007/s00592-014-0638-3 · Cited by 71 · see citing works

Contribution of brown adipose tissue activity to the control of energy balance by GLP-1 receptor signalling in mice

Heppner, K. M., Marks, S., Holland, J., Ottaway, N., Smiley, D., DiMarchi, R. D., & Pérez–Tilve, D. (2015) · Diabetologia · doi:10.1007/s00125-015-3651-3 · Cited by 44 · see citing works

Selective overexpression of human SIRT1 in adipose tissue enhances energy homeostasis and prevents the deterioration of insulin sensitivity with ageing in mice.

Xu, C., Bai, B., Fan, P., Cai, Y., Huang, B., Law, I. K. M., Liu, L., Xu, A., Tung, C., Li, X., et al. (2013) · Europe PMC (PubMed Central) · Cited by 42 · see citing works

NT-PGC-1α Activation Attenuates High-Fat Diet–Induced Obesity by Enhancing Brown Fat Thermogenesis and Adipose Tissue Oxidative Metabolism

Jun, H., Joshi, Y., Patil, Y. N., Noland, R. C., & Chang, J. S. (2014) · Diabetes · doi:10.2337/db13-1837 · Cited by 33 · see citing works

Exendin-4 improves thermogenic capacity by regulating fat metabolism on brown adipose tissue in mice with diet-induced obesity.

Wei, Q., Li, L., Chen, J., Wang, S., & Sun, Z. (2015) · PubMed · Cited by 23 · see citing works

Troglitazone prevents and reverses dexamethasone induced insulin resistance on glycogen synthesis in 3T3 adipocytes

Kumar, K. L. A., & Marita, A. R. (2000) · British Journal of Pharmacology · doi:10.1038/sj.bjp.0703313 · Cited by 19 · see citing works

Incretin hormones: Their role in health and disease

Nauck, M. A., & Meier, J. J. (2018) · Diabetes, Obesity and Metabolism · doi:10.1111/dom.13129 · Cited by 950 · see citing works

The role of adipose tissue in cardiovascular health and disease

Oikonomou, E. K., & Antoniades, C. A. (2018) · Nature Reviews Cardiology · doi:10.1038/s41569-018-0097-6 · Cited by 509 · see citing works

GLP-1 Receptor Agonists: Beyond Their Pancreatic Effects

Zhao, X., Wang, M., Wen, Z., Lu, Z., Cui, L., Fu, C., Xue, H., Liu, Y., & Zhang, Y. (2021) · Frontiers in Endocrinology · doi:10.3389/fendo.2021.721135 · Cited by 463 · see citing works

Signaling pathways in obesity: mechanisms and therapeutic interventions

Wen, X., Zhang, B., Wu, B., Xiao, H., Li, Z., Li, R., Xu, X., & Li, T. (2022) · Signal Transduction and Targeted Therapy · doi:10.1038/s41392-022-01149-x · Cited by 456 · see citing works

The anti-inflammatory and immunological properties of GLP-1 Receptor Agonists

Bendotti, G., Montefusco, L., Lunati, M. E., Usuelli, V., Pastore, I., Lazzaroni, E., Assi, E., Seelam, A. J., El Essawy, B., Jang, J., et al. (2022) · Pharmacological Research · doi:10.1016/j.phrs.2022.106320 · Cited by 406 · see citing works

Anti-inflammatory role of glucagon-like peptide 1 receptor agonists and its clinical implications

Alharbi, S. H. (2024) · Therapeutic Advances in Endocrinology and Metabolism · doi:10.1177/20420188231222367 · Cited by 358 · see citing works

Liraglutide, Sitagliptin, and Insulin Glargine Added to Metformin: The Effect on Body Weight and Intrahepatic Lipid in Patients With Type 2 Diabetes Mellitus and Nonalcoholic Fatty Liver Disease

Yan, J., Yao, B., Kuang, H., Yang, X., Huang, Q., Hong, T., Li, Y., Dou, J., Yang, W., Qin, G., et al. (2019) · Hepatology · doi:10.1002/hep.30320 · Cited by 260 · see citing works

GLP−1 receptor agonists for the treatment of obesity: Role as a promising approach

Wang, J.-Y., Wang, Q.-W., Yang, X.-Y., Yang, W., Li, D.-R., Jin, J.-Y., Zhang, H.-C., & Zhang, X.-F. (2023) · Frontiers in Endocrinology · doi:10.3389/fendo.2023.1085799 · Cited by 248 · see citing works

Inflammation and Oxidative Stress in Diabetic Kidney Disease: The Targets for SGLT2 Inhibitors and GLP-1 Receptor Agonists

Winiarska, A., Knysak, M., Nabrdalik, K., Gumprecht, J., & Stompór, T. P. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms221910822 · Cited by 195 · see citing works

The Adipokine Hypothesis of Heart Failure With a Preserved Ejection Fraction

Packer, M. (2025) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2025.06.055 · Cited by 189 · see citing works

‘Browning’ the cardiac and peri-vascular adipose tissues to modulate cardiovascular risk

Aldiss, P., Davies, G., Woods, R., Budge, H., Sacks, H. S., & Symonds, M. E. (2017) · International Journal of Cardiology · doi:10.1016/j.ijcard.2016.11.074 · Cited by 148 · see citing works

High-Fat Diet Induces Dysbiosis of Gastric Microbiota Prior to Gut Microbiota in Association With Metabolic Disorders in Mice

He, C., Cheng, D., Peng, C., Li, Y., Zhu, Y., & Lü, N. (2018) · Frontiers in Microbiology · doi:10.3389/fmicb.2018.00639 · Cited by 138 · see citing works

Liraglutide Alleviates Hepatic Steatosis by Activating the TFEB-Regulated Autophagy-Lysosomal Pathway

Fang, Y., Ji, L., Zhu, C., Xiao, Y., Zhang, J., Lu, J., Yin, J., & Wei, L. (2020) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2020.602574 · Cited by 108 · see citing works

An insight into brown/beige adipose tissue whitening, a metabolic complication of obesity with the multifactorial origin

Ziqubu, K., Dludla, P. V., Mthembu, S. X. H., Nkambule, B. B., Mabhida, S. E., Jack, B. U., Nyambuya, T. M., & Mazibuko-Mbeje, S. E. (2023) · Frontiers in Endocrinology · doi:10.3389/fendo.2023.1114767 · Cited by 96 · see citing works

A novel peptide protects against diet-induced obesity by suppressing appetite and modulating the gut microbiota

Li, Z., Zhang, B., Wang, N., Zuo, Z., Hong Kui, W. E. I., & Zhao, F. (2022) · Gut · doi:10.1136/gutjnl-2022-328035 · Cited by 83 · see citing works

Molecular mechanisms of semaglutide and liraglutide as a therapeutic option for obesity

Tamayo‐Trujillo, R., Ruiz‐Pozo, V. A., Cadena-Ullauri, S., Guevara‐Ramírez, P., Paz‐Cruz, E., Zambrano-Villacres, R., Simancas‐Racines, D., & Zambrano, A. K. (2024) · Frontiers in Nutrition · doi:10.3389/fnut.2024.1398059 · Cited by 89 · see citing works

Novel Insights into the Roles and Mechanisms of GLP-1 Receptor Agonists against Aging-Related Diseases

Peng, W., Zhou, R., Sun, Z., Long, J.-W., & Gong, Y.-Q. (2022) · Aging and Disease · doi:10.14336/ad.2021.0928 · Cited by 73 · see citing works

Autophagy-nutrient sensing pathways in diabetic complications

Parmar, U. M., Jalgaonkar, M. P., Kulkarni, Y. A., & Oza, M. J. (2022) · Pharmacological Research · doi:10.1016/j.phrs.2022.106408 · Cited by 67 · see citing works

Enteroendocrine Hormone Secretion and Metabolic Control: Importance of the Region of the Gut Stimulation

Xie, C., Jones, K. L., Rayner, C. K., & Wu, T. (2020) · Pharmaceutics · doi:10.3390/pharmaceutics12090790 · Cited by 62 · see citing works

Glucagon-Like Peptide-1 Receptor Agonists (GLP-1RAs) in the Brain–Adipocyte Axis

Geloneze, B., Júnior, J. C. D. L., & Velloso, L. A. (2017) · Drugs · doi:10.1007/s40265-017-0706-4 · Cited by 61 · see citing works

Obesity as a Multifactorial Chronic Disease: Molecular Mechanisms, Systemic Impact, and Emerging Digital Interventions

Młynarska, E., Bojdo, K., Bulicz, A., Frankenstein, H., Gąsior, M., Kustosik, N., Rysz, J., & Franczyk, B. (2025) · Current Issues in Molecular Biology · doi:10.3390/cimb47100787 · Cited by 80 · see citing works

Depot-specific UCP1 expression in human white adipose tissue and its association with obesity-related markers

Lim, J., Park, H. S., Kim, J., Jang, Y. J., Kim, J.-H., Lee, Y., & Heo, Y. (2020) · International Journal of Obesity · doi:10.1038/s41366-020-0528-4 · Cited by 56 · see citing works

Twelve weeks of exenatide treatment increases [18F] fluorodeoxyglucose uptake by brown adipose tissue without affecting oxidative resting energy expenditure in nondiabetic males

Janssen, L. G. M., Nahon, K. J., Bracké, K. F. M., van den Broek, D., Smit, R., Sardjoe Mishre, A. S. D., Koorneef, L. L., Martinez-Tellez, B., Burakiewicz, J., Kan, H. E., et al. (2020) · Metabolism · doi:10.1016/j.metabol.2020.154167 · Cited by 54 · see citing works

Browning Epicardial Adipose Tissue: Friend or Foe?

Doukbi, E., Soghomonian, A., Sengenès, C., Ahmed, S., Ancel, P., Dutour, A., & Gaborit, B. (2022) · Cells · doi:10.3390/cells11060991 · Cited by 56 · see citing works

Role of adipose tissue GLP-1R expression in metabolic improvement after bariatric surgery in patients with type 2 diabetes

Ejarque, M., Guerrero-Pérez, F., de la Morena, N., Casajoana, A., Virgili, N., López-Urdiales, R., Maymó-Masip, E., Pujol Gebelli, J., Garcia Ruiz de Gordejuela, A., Perez-Maraver, M., et al. (2019) · Scientific Reports · doi:10.1038/s41598-019-42770-1 · Cited by 53 · see citing works

Reducing Smad3/ATF4 was essential for Sirt1 inhibiting ER stress-induced apoptosis in mice brown adipose tissue

Liu, Z., Gu, H., Gan, L., Xu, Y., Feng, F., Saeed, M., & Sun, C. (2016) · Oncotarget · doi:10.18632/oncotarget.14035 · Cited by 53 · see citing works

Opposite Regulation of Ghrelin and Glucagon-like Peptide-1 by Metabolite G-Protein-Coupled Receptors

Engelstoft, M. S., & Schwartz, T. W. (2016) · Trends in Endocrinology and Metabolism · doi:10.1016/j.tem.2016.07.001 · Cited by 52 · see citing works

Mechanistic View on the Effects of SGLT2 Inhibitors on Lipid Metabolism in Diabetic Milieu

Yaribeygi, H., Maleki, M., Reiner, Ž., Jamialahmadi, T., & Sahebkar, A. (2022) · Journal of Clinical Medicine · doi:10.3390/jcm11216544 · Cited by 51 · see citing works

A compendium of G-protein–coupled receptors and cyclic nucleotide regulation of adipose tissue metabolism and energy expenditure

Ceddia, R. P., & Collins, S. (2020) · Clinical Science · doi:10.1042/cs20190579 · Cited by 51 · see citing works

Red ginseng extracts ameliorate high-fat diet-induced obesity and insulin resistance by activating the intestinal TGR5-mediated bile acids signaling pathway

Li, W., Zhuang, T., Wang, Z., Wang, X., Liu, L., Luo, Y., Wang, R., Li, L., Huang, W., Wang, Z., et al. (2023) · Phytomedicine · doi:10.1016/j.phymed.2023.154982 · Cited by 49 · see citing works

GLP-1RAs and cardiovascular disease: is the endothelium a relevant platform?

Menghini, R., Casagrande, V., Rizza, S., & Federici, M. (2023) · Acta Diabetologica · doi:10.1007/s00592-023-02124-w · Cited by 47 · see citing works

Liraglutide improves vascular dysfunction by regulating a cAMP-independent PKA-AMPK pathway in perivascular adipose tissue in obese mice

Han, F., Hou, N., Liu, Y., Huang, N., Pan, R., Zhang, X., Mao, E.-W., & Sun, X. (2019) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2019.109537 · Cited by 47 · see citing works

Ipragliflozin, an SGLT2 Inhibitor, Ameliorates High-Fat Diet-Induced Metabolic Changes by Upregulating Energy Expenditure through Activation of the AMPK/ SIRT1 Pathway

Lee, J.-Y., Lee, M., Lee, J. Y., Bae, J., Shin, E., Lee, Y., Lee, B., Kang, E. S., & Soo, B. (2021) · Diabetes & Metabolism Journal · doi:10.4093/dmj.2020.0187 · Cited by 46 · see citing works

The osteogenic effect of liraglutide involves enhanced mitochondrial biogenesis in osteoblasts

Pal, S., Maurya, S. K., Chattopadhyay, S., China, S. P., Porwal, K., Kulkarni, C., Sanyal, S., Sinha, R. A., & Chattopadhyay, N. (2019) · Biochemical Pharmacology · doi:10.1016/j.bcp.2019.03.024 · Cited by 46 · see citing works

A comprehensive insight into the effect of glutamine supplementation on metabolic variables in diabetes mellitus: a systematic review

Vayghan, H. J., Varshosaz, P., Hajizadeh‐Sharafabad, F., Razmi, H., Amirpour, M., Tavakoli‐Rouzbehani, O. M., Alizadeh, M., & Maleki, V. (2020) · Nutrition & Metabolism · doi:10.1186/s12986-020-00503-6 · Cited by 43 · see citing works

Glucagon-like peptide-1 receptor agonists decrease hyperinsulinemia and hyperandrogenemia in dehydroepiandrosterone-induced polycystic ovary syndrome mice and are associated with mitigating inflammation and inducing browning of white adipose tissue

Zhang, Y., Lin, Y., Li, G., Yuan, Y., Wang, X., Li, N., Xiong, C., Yang, Y., Ma, Y., Zhang, Z., et al. (2023) · Biology of Reproduction · doi:10.1093/biolre/ioad032 · Cited by 42 · see citing works

Geniposide Protects against Obesity‐Related Cardiac Injury through AMPKα‐ and Sirt1‐Dependent Mechanisms

Ma, Z., Kong, C., Song, P. K., Zhang, X., Yuan, Y., & Tang, Q. (2018) · Oxidative Medicine and Cellular Longevity · doi:10.1155/2018/6053727 · Cited by 42 · see citing works

Antidiabetic GLP-1 Receptor Agonists Have Neuroprotective Properties in Experimental Animal Models of Alzheimer’s Disease

Urkon, M., Ferencz, E., Szász, J. A., Szabó, M. I. M., Orbán-Kis, K., Szatmári, S., & Nagy, E. E. (2025) · Pharmaceuticals · doi:10.3390/ph18050614 · Cited by 40 · see citing works

An estrogen receptor α-derived peptide improves glucose homeostasis during obesity

Yang, W., Jiang, W., Liao, W., Yan, H., Ai, W., Pan, Q., Brashear, W. A., Xu, Y., He, L., & Guo, S. (2024) · Nature Communications · doi:10.1038/s41467-024-47687-6 · Cited by 38 · see citing works

Transcription Regulators and Hormones Involved in the Development of Brown Fat and White Fat Browning: Transcriptional and Hormonal Control of Brown/Beige Fat Development

Zhang, J., Wu, H., MA, S., Jing, F., Yu, C., Gao, L., & Zhao, J. (2018) · Physiological Research · doi:10.33549/physiolres.933650 · Cited by 38 · see citing works

Beige Adipocyte as the Flame of White Adipose Tissue: Regulation of Browning and Impact of Obesity

Altınova, A. E. (2021) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/clinem/dgab921 · Cited by 39 · see citing works

The effect of glucagon-like peptide 1 and glucagon-like peptide 1 receptor agonists on energy expenditure: A systematic review and meta-analysis

Maciel, M. G., Beserra, B. T. S., Oliveira, F. C. B., Ribeiro, C. M., Coêlho, M. S., Neves, F. D. A. R., & Amato, A. A. (2018) · Diabetes Research and Clinical Practice · doi:10.1016/j.diabres.2018.05.034 · Cited by 36 · see citing works

Proteomic analysis reveals semaglutide impacts lipogenic protein expression in epididymal adipose tissue of obese mice

Zhu, R., & Chen, S. (2023) · Frontiers in Endocrinology · doi:10.3389/fendo.2023.1095432 · Cited by 36 · see citing works

Malonylation of Acetyl-CoA carboxylase 1 promotes hepatic steatosis and is attenuated by ketogenic diet in NAFLD

Cao, H., Cai, Q., Guo, W., Su, Q., Qin, H., Wang, T., Xian, Y., Zeng, L., Cai, M., Guan, H., et al. (2023) · Cell Reports · doi:10.1016/j.celrep.2023.112319 · Cited by 35 · see citing works

Adipose Tissue in Cardiovascular Disease: From Basic Science to Clinical Translation

Polkinghorne, M., West, H. W., & Antoniades, C. A. (2023) · Annual Review of Physiology · doi:10.1146/annurev-physiol-042222-021346 · Cited by 34 · see citing works

Glucagon-Like Peptide-1 Receptor Agonist Differentially Affects Brain Activation in Response to Visual Food Cues in Lean and Obese Individuals with Type 2 Diabetes Mellitus

Bae, J. H., Choi, H. J., Cho, K. I. K., Kim, L. K., Kwon, J. S., & Cho, Y. M. (2020) · Diabetes & Metabolism Journal · doi:10.4093/dmj.2019.0018 · Cited by 33 · see citing works

Novel GLP-1 Analog Supaglutide Reduces HFD-Induced Obesity Associated with Increased Ucp-1 in White Adipose Tissue in Mice

Wan, Y., Bao, X., Huang, J., Zhang, X., Liu, W., Cui, Q., Jiang, D., Wang, Z., Liu, R., & Wang, Q. (2017) · Frontiers in Physiology · doi:10.3389/fphys.2017.00294 · Cited by 33 · see citing works

Short-term GLP-1 receptor agonist exenatide ameliorates intramyocellular lipid deposition without weight loss in ob/ob mice

Xu, F., Cao, H., Chen, Z., Gu, H., Guo, W., Lin, B., & Weng, J. (2020) · International Journal of Obesity · doi:10.1038/s41366-019-0513-y · Cited by 31 · see citing works

Ecklonia Cava Extract Attenuates Endothelial Cell Dysfunction by Modulation of Inflammation and Brown Adipocyte Function in Perivascular Fat Tissue

Son, M., Oh, S., Lee, H. S., Chung, D.-M., Jang, J. T., Jeon, Y., Choi, C. H., Park, K. Y., Son, K. H., & Byun, K. (2019) · Nutrients · doi:10.3390/nu11112795 · Cited by 31 · see citing works

Liraglutide Activates Type 2 Deiodinase and Enhances β3-Adrenergic-Induced Thermogenesis in Mouse Adipose Tissue

Oliveira, F. C. B., Bauer, E. J., Ribeiro, C. M., Pereira, S. A., Beserra, B. T. S., Wajner, S. M., Maia, A. L., Neves, F. A. R., Coelho, M. S., & Amato, A. A. (2022) · Frontiers in Endocrinology · doi:10.3389/fendo.2021.803363 · Cited by 30 · see citing works

Exenatide attenuates obesity-induced mitochondrial dysfunction by activating SIRT1 in renal tubular cells

Wang, Y., He, W., Wei, W., Mei, X., Yang, M., & Wang, Y. (2021) · Frontiers in Endocrinology · doi:10.3389/fendo.2021.622737 · Cited by 30 · see citing works

Unlocking the multifaceted roles of GLP-1: Physiological functions and therapeutic potential

AL-Noshokaty, T. M., Abdelhamid, R., Abdelmaksoud, N. M., Khaled, A., Hossam, M., Ahmed, R., Saber, T., Khaled, S., Elshaer, S. S., & Abulsoud, A. I. (2025) · Toxicology Reports · doi:10.1016/j.toxrep.2025.101895 · Cited by 30 · see citing works

Glucagon-like peptide-1 receptor agonist stimulates mitochondrial bioenergetics in human adipocytes

Góralska, J., Śliwa, A., Gruca, A., Raźny, U., Chojnacka, M., Polus, A., Solnica, B., & Malczewska-Malec, M. (2017) · Acta Biochimica Polonica · doi:10.18388/abp.2017_1634 · Cited by 30 · see citing works

Brown and beige adipose tissue: New therapeutic targets for metabolic disorders

Magro, B. S., & Dias, D. P. M. (2024) · Health Sciences Review · doi:10.1016/j.hsr.2024.100148 · Cited by 32 · see citing works

GLP-1RA promotes brown adipogenesis of C3H10T1/2 mesenchymal stem cells via the PI3K-AKT-mTOR signaling pathway

Wang, X., Chen, J., Rong, C., Pan, F., Zhao, X., & Hu, Y. (2018) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2018.10.197 · Cited by 29 · see citing works

Laminarin counteracts diet-induced obesity associated with glucagon-like peptide-1 secretion

Yang, L., Wang, L., Zhu, C., Wu, J., Yuan, Y., Yu, L., Xu, Y., Xu, J., Wang, T., Liao, Z., et al. (2017) · Oncotarget · doi:10.18632/oncotarget.19957 · Cited by 27 · see citing works

Caveolin-1 deficiency protects pancreatic β cells against palmitate-induced dysfunction and apoptosis

Zeng, W., Tang, J., Li, H., Xu, H., Lu, H., Peng, H., Lin, C., Gao, R., Lin, S., Lin, K., et al. (2018) · Cellular Signalling · doi:10.1016/j.cellsig.2018.03.013 · Cited by 27 · see citing works

The Impact of Incretin-Based Medications on Lipid Metabolism

Yaribeygi, H., Maleki, M., Butler, A. E., Jamialahmadi, T., & Sahebkar, A. (2021) · Journal of Diabetes Research · doi:10.1155/2021/1815178 · Cited by 27 · see citing works

Adipose Tissue Composition in Obesity and After Bariatric Surgery

Adami, G. F., Carbone, F., Montecucco, F., Camerini, G. B., & Cordera, R. (2019) · Obesity Surgery · doi:10.1007/s11695-019-04030-z · Cited by 26 · see citing works

Gene expression modulation of lipid and central energetic metabolism related genes by high-fat diet intake in the main homeostatic tissues

Reynés, B., Palou, M., & Palou, A. (2016) · Food & Function · doi:10.1039/c6fo01473a · Cited by 26 · see citing works

Brown and Beige Adipose Tissue: One or Different Targets for Treatment of Obesity and Obesity-Related Metabolic Disorders?

Kononova, Y. A., Тучина, Т. П., & Babenko, A. Y. (2024) · International Journal of Molecular Sciences · doi:10.3390/ijms252413295 · Cited by 28 · see citing works

Activation of Brown Adipose Tissue and Promotion of White Adipose Tissue Browning by Plant-based Dietary Components in Rodents: A Systematic Review

Osuna‐Prieto, F. J., Martínez‐Téllez, B., Segura‐Carretero, A., & Ruiz, J. R. (2021) · Advances in Nutrition · doi:10.1093/advances/nmab084 · Cited by 25 · see citing works

Liraglutide improves lipid and carbohydrate metabolism of ovariectomized rats

Model, J. F. A., Lima, M. V., Ohlweiler, R., Vogt, É. L., Rocha, D. S., de Souza, S. K., Türck, P., Araújo, A. S. D. R., & Vinagre, A. S. (2021) · Molecular and Cellular Endocrinology · doi:10.1016/j.mce.2021.111158 · Cited by 23 · see citing works

Effects of rikkunshito on renal fibrosis and inflammation in angiotensin II-infused mice

Azushima, K., Uneda, K., Wakui, H., Ohki, K., Haruhara, K., Kobayashi, R., Haku, S., Kinguchi, S., Yamaji, T., Minegishi, S., et al. (2019) · Scientific Reports · doi:10.1038/s41598-019-42657-1 · Cited by 22 · see citing works

DPP-IV as a potential candidate in anti-obesity and obesity-related diseases treatment

Guo, X., Feng, H., Cai, L., Zheng, J., & Li, Y. (2024) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2024.117464 · Cited by 21 · see citing works

The effects of glucagon-like peptide-1 receptor agonists on glycemic control and anthropometric profiles among diabetic patients with non-alcoholic fatty liver disease: A systematic review and meta-analysis of randomized controlled trials

Nowrouzi‐Sohrabi, P., Rezaei, S., Jalali, M., Ashourpour, M., Ahmadipour, A., Keshavarz, P., & Akbari, H. (2020) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2020.173823 · Cited by 21 · see citing works

Metformin Alleviates Steatohepatitis in Diet-Induced Obese Mice in a SIRT1-Dependent Way

Guo, W., Liu, J., Cheng, L., Liu, Z., Zheng, X., Liang, H., & Xu, F. L. (2021) · Frontiers in Pharmacology · doi:10.3389/fphar.2021.704112 · Cited by 21 · see citing works

Free fatty acid receptors in the endocrine regulation of glucose metabolism: Insight from gastrointestinal-pancreatic-adipose interactions

Zhao, Y.-F. (2022) · Frontiers in Endocrinology · doi:10.3389/fendo.2022.956277 · Cited by 21 · see citing works

Balancing Act: Exploring the Gut Microbiota-Brown Adipose Tissue Axis in PCOS Pathogenesis and Therapeutic Frontiers

Li, Y., Fang, Y., Wang, H., & Zhang, H. (2024) · Frontiers in Bioscience-Landmark · doi:10.31083/j.fbl2906208 · Cited by 21 · see citing works

Effects of antidiabetic drugs on epicardial fat

Xourgia, E., Papazafiropoulou, A. K., & Melidonis, A. J. (2018) · World Journal of Diabetes · doi:10.4239/wjd.v9.i9.141 · Cited by 21 · see citing works

Mechanisms and pharmacotherapy of cancer cachexia‐associated anorexia

Sato, R., da Fonseca, G. W. P., das Neves, W., & von Haehling, S. (2025) · Pharmacology Research & Perspectives · doi:10.1002/prp2.70031 · Cited by 21 · see citing works

Proglucagon-Derived Peptides, Glucose-Dependent Insulinotropic Polypeptide, and Dipeptidyl Peptidase-4-Mechanisms of Action in Adipose Tissue

Beaudry, J. L., & Drucker, D. J. (2019) · Endocrinology · doi:10.1210/endocr/bqz029 · Cited by 20 · see citing works

Spatiotemporal control of GLP-1 receptor activity

Manchanda, Y., Bitsi, S., Kang, Y., Jones, B. J., & Tomás, A. (2020) · Current Opinion in Endocrine and Metabolic Research · doi:10.1016/j.coemr.2020.07.003 · Cited by 20 · see citing works

Glucagon-like Peptide 1 Receptor Agonists in Cardio-Oncology: Pathophysiology of Cardiometabolic Outcomes in Cancer Patients

Quagliariello, V., Canale, M. L., Bisceglia, I., Iovine, M., Giordano, V., Giacobbe, I., Scherillo, M., Gabrielli, D., Maurea, C., Barbato, M., et al. (2024) · International Journal of Molecular Sciences · doi:10.3390/ijms252011299 · Cited by 20 · see citing works

Pharmacological modulation of adaptive thermogenesis: new clues for obesity management?

Genchi, V. A., Palma, G., Sorice, G. P., D’Oria, R., Caccioppoli, C., Marrano, N., Biondi, G., Caruso, I., Cignarelli, A., Natalicchio, A., et al. (2023) · Journal of Endocrinological Investigation · doi:10.1007/s40618-023-02125-0 · Cited by 19 · see citing works

GLP-1 Induces the Expression of FNDC5 Derivatives That Execute Lipolytic Actions

Li, H., Donelan, W., Wang, F., Zhang, P., Yang, L., Ding, Y., Tang, D., & Li, S. (2021) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2021.777026 · Cited by 18 · see citing works

Recent advances in the understanding of how neuropeptide Y andα-melanocyte stimulating hormone function in adipose physiology

Shipp, S. L., Cline, M. A., & Gilbert, E. R. (2016) · Adipocyte · doi:10.1080/21623945.2016.1208867 · Cited by 18 · see citing works

Tumor cell-adipocyte gap junctions activate lipolysis and contribute to breast tumorigenesis

Williams, J., Camarda, R., Malkov, S., Zimmerman, L. J., Manning, S., Aran, D., Beardsley, A. R., de Mark, D. V., Nakagawa, R. M., Chen, Y., et al. (2025) · Nature Communications · doi:10.1038/s41467-025-62486-3 · Cited by 17 · see citing works

Exenatide mitigates inflammation and hypoxia along with improved angiogenesis in obese fat tissue

Xian, Y., Chen, Z., Deng, H., Cai, M., Liang, H., Xu, W., Weng, J., & Xu, F. L. (2019) · Journal of Endocrinology · doi:10.1530/joe-18-0639 · Cited by 17 · see citing works

Role of endogenous glucagon‐like peptide‐1 enhanced by vildagliptin in the glycaemic and energy expenditure responses to intraduodenal fat infusion in type 2 diabetes

Xie, C., Wang, X., Jones, K. L., Horowitz, M., Sun, Z., Little, T. J., Rayner, C. K., & Wu, T. (2019) · Diabetes Obesity and Metabolism · doi:10.1111/dom.13906 · Cited by 17 · see citing works

Adipose Tissue: A Novel Target of the Incretin Axis? A Paradigm Shift in Obesity-Linked Insulin Resistance

De Fano, M., Malara, M., Vermigli, C., & Murdolo, G. (2024) · International Journal of Molecular Sciences · doi:10.3390/ijms25168650 · Cited by 17 · see citing works

The GLP-1 Receptor Agonist Dulaglutide Attenuates Hepatic Steatosis in Obesity via a Weight-Independent Mechanism

Shantaram, D., Rima, X. Y., Bradley, D. P., Liu, J. Z., Wright, V. P., AMARI, A., Jalilvand, A., Rottinghaus, J., Fernandes, J. M., Smith, A. J., et al. (2025) · Diabetes · doi:10.2337/db24-0861 · Cited by 16 · see citing works

Adipose tissue mitochondrial dysfunction and cardiometabolic diseases: On the search for novel molecular targets

AlZaim, I., Eid, A. H., Abd‐Elrahman, K. S., & EL‐Yazbi, A. F. (2022) · Biochemical Pharmacology · doi:10.1016/j.bcp.2022.115337 · Cited by 16 · see citing works

Oleoylethanolamide modulates glucagon-like peptide-1 receptor agonist signaling and enhances exendin-4-mediated weight loss in obese mice

Brown, J. D., McAnally, D., Ayala, J. E., Burmeister, M. A., Morfa, C. J., Smith, L. H., & Ayala, J. E. (2018) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.00459.2017 · Cited by 16 · see citing works

D-allulose ameliorates adiposity through the AMPK-SIRT1-PGC-1α pathway in HFD-induced SD rats

Lee, G., Peng, C. Y., Lee, H., Park, S., Hoang, T., Kim, J., Sa, S., Kim, G., Han, J.-S., & Chae, H. (2021) · Food & Nutrition Research · doi:10.29219/fnr.v65.7803 · Cited by 16 · see citing works

Cardiovascular disease leads to a new algorithm for diabetes treatment

Rodriguez, V., Weiss, M. C., WEINTRAUB, H. S., Goldberg, I. J., & Schwartzbard, A. Z. (2017) · Journal of clinical lipidology · doi:10.1016/j.jacl.2017.07.004 · Cited by 15 · see citing works

Depot-specific adipose tissue modulation by SGLT2 inhibitors and GLP1 agonists mediates their cardioprotective effects in metabolic disease

Bakkar, N. Z., AlZaim, I., & EL‐Yazbi, A. F. (2022) · Clinical Science · doi:10.1042/cs20220404 · Cited by 15 · see citing works

Fighting Type-2 Diabetes: Present and Future Perspectives

Yu, C., Fu, Y., Fang, Y., Zhang, N., Sun, R., Zhao, D., Feng, Y., & Zhang, B. (2017) · Current Medicinal Chemistry · doi:10.2174/0929867324666171009115356 · Cited by 15 · see citing works

Liraglutide induced browning of visceral white adipose through regulation of miRNAs in high-fat-diet-induced obese mice

Zhao, L. Q., Li, W., Zhang, P., Wang, D., Yang, L., & Yuan, G. (2024) · Endocrine · doi:10.1007/s12020-024-03734-2 · Cited by 14 · see citing works

Effects of liraglutide on intrapancreatic fat deposition in patients with type 2 diabetes

Kuriyama, T., Ishibashi, C., Kozawa, J., Baden, M. Y., Horii, T., Niki, A., Ozawa, H., Hosokawa, Y., Fujita, Y., Sadahiro, K., et al. (2023) · Clinical Nutrition ESPEN · doi:10.1016/j.clnesp.2023.12.005 · Cited by 14 · see citing works

From diabetes to diverse domains: the multifaceted roles of GLP-1 receptor agonists

Dave, B. P., Chorawala, M. R., Shah, I., Shah, N. N., Bhagat, S. U., Prajapati, B. G., & Thakkar, P. C. (2024) · Molecular Biology Reports · doi:10.1007/s11033-024-09793-y · Cited by 12 · see citing works

Beyond obesity – thermogenic adipocytes and cardiometabolic health

Aldiss, P., Dellschaft, N. S., Sacks, H. S., Budge, H., & Symonds, M. E. (2017) · Hormone Molecular Biology and Clinical Investigation · doi:10.1515/hmbci-2017-0007 · Cited by 11 · see citing works

Anti-obesogenic and hypolipidemic effects of a glucagon-like peptide-1 receptor agonist derived from the saliva of the Gila monster

Alves, P. L., Abdalla, F. M. F., Alponti, R. F., & Silveira, P. F. (2017) · Toxicon · doi:10.1016/j.toxicon.2017.06.001 · Cited by 11 · see citing works

Effects of glucagon-like peptide-1 receptor agonists on spermatogenesis-related gene expression in mouse testis and testis-derived cell lines

Masashi, I. I. D. A., & Asano, A. (2024) · Journal of Veterinary Medical Science · doi:10.1292/jvms.24-0042 · Cited by 11 · see citing works

RNA-Seq and WGCNA Identify Key Regulatory Modules and Genes Associated with Water-Holding Capacity and Tenderness in Sheep

Zhao, L., Li, F., Zhang, X., Tian, H., Ma, Z., Yang, X., Zhang, Q., Pu, M., Cao, P., Zhang, D., et al. (2025) · Animals · doi:10.3390/ani15111569 · Cited by 10 · see citing works

Impact of Interplay between Obese Gut Microbiota and Diet in Developing Obesity in Synthetic Community Mice

Liaqat, I., Naseem, S., Eijaz, S., Hanif, U., Rubab, S., Aftab, M. N., & Iqbal, R. (2021) · Journal of Oleo Science · doi:10.5650/jos.ess21148 · Cited by 10 · see citing works

Targeting obesity for therapeutic intervention in heart failure patients

Sato, R., & von Haehling, S. (2024) · Expert Review of Cardiovascular Therapy · doi:10.1080/14779072.2024.2363395 · Cited by 10 · see citing works

Overexpression of METTL14 mediates steatohepatitis and insulin resistance in mice

Zhou, J., Yang, M., Zhai, D.-G., Jiang, Q. L., & Zhang, Q. (2024) · Heliyon · doi:10.1016/j.heliyon.2024.e35467 · Cited by 9 · see citing works

The expanding role of semaglutide: beyond glycemic control

Zarei, M., Sabetkasaei, M., Mozafari, M., & Zaeri, S. (2025) · Journal of Diabetes & Metabolic Disorders · doi:10.1007/s40200-025-01663-z · Cited by 9 · see citing works

GLP-1 receptor agonist protects glucose-stimulated insulin secretion in pancreatic β-cells against lipotoxicity via PPARδ/UCP2 pathway

Liu, Z., Chen, Y., Su, Y., PENG, Y., Xu, F. L., Yao, B., Liang, H., Lin, B., & Xu, W. (2025) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-025-05844-0 · Cited by 9 · see citing works

Exendin-4 Upregulates Adiponectin Level in Adipocytes via Sirt1/Foxo-1 Signaling Pathway

Wang, A., Li, T., An, P., Yan, W., Zheng, H., Wang, B., & Mu, Y. (2017) · PLOS ONE · doi:10.1371/journal.pone.0169469 · Cited by 58 · see citing works

Glucagon-like peptide-1 receptor agonist stimulates mitochondrial bioenergetics in human adipocytes

Góralska, J., Śliwa, A., Gruca, A., Raźny, U., Chojnacka, M., Polus, A., Solnica, B., & Malczewska-Malec, M. (2017) · Acta Biochimica Polonica · doi:10.18388/abp.2017_1634 · Cited by 30 · see citing works

319-LB: GLP-1 Receptor Agonist Promotes Brown Remodeling in? Human Adipose-Derived Stromal Cells Isolated from Omentum through Foxc2

He, X., Liu, L., Ke, W., & Li, Y. (2019) · Diabetes · doi:10.2337/db19-319-lb

Contribution of brown adipose tissue activity to the control of energy balance by GLP-1 receptor signalling in mice

Heppner, K. M., Marks, S., Holland, J., Ottaway, N., Smiley, D., DiMarchi, R. D., & Pérez–Tilve, D. (2015) · Diabetologia · doi:10.1007/s00125-015-3651-3 · Cited by 44 · see citing works

Adiponectin/SIRT1 Axis Induces White Adipose Browning After Vertical Sleeve Gastrectomy of Obese Rats with Type 2 Diabetes

Liu, L., Zhang, T., Hu, J., Ma, R., He, B., Wang, M., & Wang, Y. (2019) · Obesity Surgery · doi:10.1007/s11695-019-04295-4 · Cited by 40 · see citing works