The DOI matches its Crossref record; 47 of the 47 references it cites were found in a registry or an index.
Effects of caffeine on performance and mood depend on the level of caffeine abstinence
Open accessAbstract
Rationale Most studies of the effects of caffeine on performance have used regular caffeine consumers who are deprived at test. Thus the reported effects of caffeine could be explained through reversal of caffeine withdrawal.Objectives To test how preloading deprived caffeine consumers with 0, 1 or 2 mg/kg caffeine altered the subsequent ability of caffeine to modify mood and performance.Methods Thirty moderate caffeine consumers were given a drink containing 0, 1 or 2 mg/kg caffeine at breakfast followed 60 min later by a second drink containing either 0 or 1 mg/kg caffeine. Performance on a measure of sustained attention and mood were measured before and after each drink.Results Administration of both 1 and 2 mg/kg caffeine at breakfast decreased reaction time and 1 mg/kg caffeine also increased performance accuracy on the sustained attention (RVIP) task relative to placebo. Both breakfast doses of caffeine also improved rated mental alertness. Similarly, 1 mg/kg caffeine administered 60 min after breakfast decreased reaction time and increased rated mental alertness in the group who had not been given caffeine at breakfast. However, this second dose of caffeine had no effect on subsequent performance or mood in the two groups who had received caffeine at breakfast.Conclusions Caffeine reliably improved performance on a sustained attention task, and increased rated mental alertness, in moderate caffeine consumers who were tested when caffeine-deprived. However, caffeine had no such effects when consumers were no longer caffeine deprived. These data are consistent with the view that reversal of caffeine withdrawal is a major component of the effects of caffeine on mood and performance.
Overview
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“The impact of caffeine appears to be greater under conditions that would negatively impact performance, such as acute caffeine withdrawal (74–76) or sleep deprivation (71, 77).”
From The Safety of Ingested Caffeine: A Comprehensive Review (2017) · cites this paper as [75]
Citations
Cites
The use of analogue scales in rating subjective feelings
BOND, A., & LADER, M. (1974) · British Journal of Medical Psychology · doi:10.1111/j.2044-8341.1974.tb02285.x · Cited by 1,972
The effects of low doses of caffeine on human performance and mood
Lieberman, H. R., Wurtman, R. J., Emde, G. G., Roberts, C., & Coviella, I. L. G. (1987) · Psychopharmacology · doi:10.1007/bf00210835 · Cited by 413
Withdrawal Syndrome after the Double-Blind Cessation of Caffeine Consumption
Silverman, K., Evans, S. M., Strain, E. C., & Griffiths, R. R. (1992) · New England Journal of Medicine · doi:10.1056/nejm199210153271601 · Cited by 380
Smit, H. J., & Rogers, P. J. (2000) · Psychopharmacology · doi:10.1007/s002130000506 · Cited by 339
Self-citationBreakfast, blood glucose, and cognition
Benton, D., & Parker, P. (1998) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/67.4.772s · Cited by 270
James, J. E. (1991) · Academic Press eBooks · Cited by 184
Effects of Breakfast and Caffeine on Cognitive Performance, Mood and Cardiovascular Functioning
Smith, A. P., Kendrick, A., Maben, A., & Salmon, J. (1994) · Appetite · doi:10.1006/appe.1994.1004 · Cited by 179
Acute and chronic effects of caffeine on performance, mood, headache, and sleep
James, J. E. (1998) · Neuropsychobiology · doi:10.1159/000026514 · Cited by 157
Rogers, P. J., & Dernoncourt, C. (1998) · Pharmacology Biochemistry and Behavior · doi:10.1016/s0091-3057(97)00515-7 · Cited by 157
Self-citationEffects of caffeine on cognition and mood without caffeine abstinence
Warburton, D. M. (1995) · Psychopharmacology · doi:10.1007/bf02246055 · Cited by 149
Mood and performance effects of caffeine in relation to acute and chronic caffeine deprivation
Richardson, N. J., Rogers, P. J., Elliman, N. A., & O'Dell, R. (1995) · Pharmacology Biochemistry and Behavior · doi:10.1016/0091-3057(95)00029-v · Cited by 137
Self-citationInfluence of caffeine on information processing stages in well rested and fatigued subjects
Lorist, M. M., Snel, J., & Kok, A. (1994) · Psychopharmacology · doi:10.1007/bf02245217 · Cited by 133
Caffeine and diazepam: Separate and combined effects on mood, memory, and psychomotor performance
Loke, W. H., Hinrichs, J. V., & Ghoneim, M. M. (1985) · Psychopharmacology · doi:10.1007/bf00432719 · Cited by 125
Interactions of diazepam and caffeine: Behavioral and subjective dose effects in humans
Roache, J. D. (1987) · Pharmacology Biochemistry and Behavior · doi:10.1016/0091-3057(87)90614-9 · Cited by 118
Rogers, P. J., Richardson, N., & Elliman, N. A. (1995) · Psychopharmacology · doi:10.1007/bf02245818 · Cited by 116
Self-citationThe Effects of Caffeine and Aspirin on Mood and Performance
Lieberman, H. R., Wurtman, R. J., Emde, G. G., & López-Coviella, I. (1987) · Journal of Clinical Psychopharmacology · doi:10.1097/00004714-198710000-00004 · Cited by 114
Does Caffeine Enhance or Merely Restore Degraded Psychomotor Performance?
James, J. E. (2008) · Neuropsychobiology · doi:10.1159/000119151 · Cited by 112
Absorption rate of methylxanthines following capsules, cola and chocolate
Mumford, G. K., Benowitz, N. L., Evans, S. M., Kaminski, B. J., Preston, K. L., Sannerud, C. A., Silverman, K., & Griffiths, R. R. (1996) · European Journal of Clinical Pharmacology · doi:10.1007/s002280050205 · Cited by 111
The effect of caffeine on human performance, alone and in combination with ethanol
Franks, H. M., Hagedorn, H., Hensley, V. R., Hensley, W. J., & Starmer, G. A. (1975) · Psychopharmacology · doi:10.1007/bf00429058 · Cited by 106
Investigation of the Effects of Coffee on Alertness and Performance during the Day and Night
Smith, A. P., BROCKMAN, P., Flynn, R., Maben, A., & Thomas, M. (2008) · Neuropsychobiology · doi:10.1159/000118984 · Cited by 104
Effects of Caffeine Given before and after Lunch on Sustained Attention
Smith, A. P., Rusted, J. M., Eaton-Williams, P., Savory, M., & Leathwood, P. D. (2008) · Neuropsychobiology · doi:10.1159/000119444 · Cited by 102
Self-citationThe influences of age and caffeine on psychomotor and cognitive function
Rees, K., Allen, D., & Lader, M. (1999) · Psychopharmacology · doi:10.1007/s002130051047 · Cited by 101
Effects of a low dose of caffeine given in different drinks on mood and performance
Smith, A. P., Sturgess, W., & Gallagher, J. (1999) · Human Psychopharmacology Clinical and Experimental · doi:10.1002/(sici)1099-1077(199910)14:7 · Cited by 100
Dusseldorp, M., & Katan, M. (1990) · BMJ · doi:10.1136/bmj.300.6739.1558 · Cited by 92
Effects of Evening Meals and Caffeine on Cognitive Performance, Mood and Cardiovascular Functioning
Smith, A. P., Maben, A., & BROCKMAN, P. (1994) · Appetite · doi:10.1006/appe.1994.1005 · Cited by 85
Conditioned flavour preference negatively reinforced by caffeine in human volunteers
Yeomans, M. R., Spetch, H., & Rogers, P. J. (1998) · Psychopharmacology · doi:10.1007/s002130050636 · Cited by 83
Self-citationThe effects of a low dose of caffeine on cognitive performance
Durlach, P. J. (1998) · Psychopharmacology · doi:10.1007/s002130050746 · Cited by 81
Hasenfratz, M., & Bättig, K. (1994) · Psychopharmacology · doi:10.1007/bf02244850 · Cited by 80
Alerting effects of caffeine after normal and restricted sleep.
Rosenthal, L. D., Roehrs, T., Zwyghuizen‐Doorenbos, A., Plath, D., & Roth, T. G. (1991) · PubMed · Cited by 75
Effects of caffeine use and ingestion on a protracted visual vigilance task
Loke, W. H., & Meliska, C. J. (1984) · Psychopharmacology · doi:10.1007/bf00432024 · Cited by 74
LOW‐DOSE CAFFEINE DISCRIMINATION AND SELF‐REPORTED MOOD EFFECTS IN NORMAL VOLUNTEERS
Silverman, K., & Griffiths, R. R. (1992) · Journal of the Experimental Analysis of Behavior · doi:10.1901/jeab.1992.57-91 · Cited by 74
Robelin, M., & Rogers, P. J. (1998) · Behavioural Pharmacology · doi:10.1097/00008877-199811000-00016 · Cited by 68
Self-citationHigh doses of caffeine impair performance of a numerical version of the stroop task in men
Foreman, N., Barraclough, S., Moore, C., Mehta, A., & Madon, M. (1989) · Pharmacology Biochemistry and Behavior · doi:10.1016/0091-3057(89)90169-x · Cited by 67
Caffeine effects on perceptual and motor processes
Lorist, M. M., & Snel, J. (1997) · Electroencephalography and Clinical Neurophysiology · doi:10.1016/s0921-884x(97)95729-5 · Cited by 60
Effects of caffeine on vigilance and other performance tests in normal subjects
Fagan, D., Swift, C. G., & Tiplady, B. (1988) · Journal of Psychopharmacology · doi:10.1177/026988118800200104 · Cited by 55
Expression of flavour preferences conditioned by caffeine is dependent on caffeine deprivation state
Yeomans, M. R., Jackson, A. E., Lee, M. D., Nešić, J., & Durlach, P. J. (2000) · Psychopharmacology · doi:10.1007/s002130000405 · Cited by 46
Self-citationClozapine Drug-Drug Interactions: A Review of the Literature
EDGE, S. C., Markowitz, J. S., & DeVane, C. L. (1997) · Human Psychopharmacology Clinical and Experimental · doi:10.1002/(sici)1099-1077(199701/02)12:1 · Cited by 46
Caffeine and visuo-spatial attention
Kenemans, J. L., & Verbaten, M. N. (1998) · Psychopharmacology · doi:10.1007/s002130050522 · Cited by 44
Caffeine Consumption and Target Scanning Performance
Childs, J. M. (1978) · Human Factors The Journal of the Human Factors and Ergonomics Society · doi:10.1177/001872087802000112 · Cited by 33
The influence of user status and anxious disposition on the hypertensive effects of caffeine
James, J. E. (1990) · International Journal of Psychophysiology · doi:10.1016/0167-8760(90)90031-8 · Cited by 32
Caffeine, Mood, and Performance
Stafford, L. D., Rusted, J. M., & Yeomans, M. R. (2006) · CRC Press eBooks · doi:10.1201/9781420006568-11 · Cited by 22
Self-citationNo evidence for latent learning of liking for flavours conditioned by caffeine
Yeomans, M. R., Ripley, T. L., Lee, M., & Durlach, P. J. (2001) · Psychopharmacology · doi:10.1007/s002130100765 · Cited by 21
Self-citationCeledón, J. M., Colombo, M., & López, I. (1983) · PubMed · Cited by 20
Caffeine and cognitive performance: effects on mood or mental processing?
Rusted, J. M. (2020) · doi:10.4324/9780429271038-13 · Cited by 17
Self-citationRogers, P. J. (2000) · Bristol Research (University of Bristol) · Cited by 8
Self-citationMeyer, F., Walther, T., & Walther, H. (1983) · Pharmacopsychiatry · doi:10.1055/s-2007-1017441 · Cited by 5
SSRIs in depression: a decade of progress
Goldstein, B. J. (1998) · Journal of Psychopharmacology · doi:10.1177/0269881198012003011 · Cited by 5
Cited by
Sorted by citations
Juliano, L. M., & Griffiths, R. R. (2004) · Psychopharmacology · doi:10.1007/s00213-004-2000-x · Cited by 613
The Safety of Ingested Caffeine: A Comprehensive Review
Temple, J. L., Bernard, C., Lipshultz, S. E., Czachor, J. D., Westphal, J. A., & Mestre, M. A. (2017) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2017.00080 · Cited by 557
Effects of caffeine on performance and mood: withdrawal reversal is the most plausible explanation
James, J. E., & Rogers, P. J. (2005) · Psychopharmacology · doi:10.1007/s00213-005-0084-6 · Cited by 231
Self-citationCaffeine, Mental Health, and Psychiatric Disorders
Lara, D. R. (2010) · Journal of Alzheimer s Disease · doi:10.3233/jad-2010-1378 · Cited by 245
Caffeine as an Attention Enhancer: Reviewing Existing Assumptions
Einöther, S. J. L., & Giesbrecht, T. (2013) · Psychopharmacology · doi:10.1007/s00213-012-2917-4 · Cited by 215
Metadata
- Authors
- Yeomans, M., Ripley, T., Davies, L., Rusted, J., & Rogers, P.
- Affiliations
- University of Sussex (GB)
- University of Bristol (GB)
- Corresponding author
- Yeomans, Martin
- Venue
- Psychopharmacology
- Published
- 2002-11-01
- Volume
- 164
- Issue
- 3
- Pages
- 241-249
- ISSN
- 0033-3158 (ISSN-L)
- 1432-2072
- OpenAlex
- W2151484680
- Cited by
- 130
- References
- 47
- Citations by year
- 2025: 3 · 2024: 4 · 2023: 1 · 2022: 4 · 2021: 1 · 2020: 3 · 2019: 4 · 2018: 6 · 2017: 3 · 2016: 6 · 2015: 3 · 2014: 7 · 2013: 6 · 2012: 11
- FWCI
- 5.04
- Type
- journal article
- Language
- en
- Open access
- green
- figshare.com
- Licence
- Locations
- Psychopharmacology (publishedVersion)
- PubMed (publishedVersion)
- Explore Bristol Research (publishedVersion)
- Figshare (submittedVersion, cc-by)
- Topics
- Health Sciences › Medicine › Pharmacology (medical) › Coffee research and impacts
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Sleep and Work-Related Fatigue
- Life Sciences › Neuroscience › Cognitive Neuroscience › Mind wandering and attention
- Keywords
- caffeine, caffeine withdrawal, caffeine abstinence, sustained attention, reaction time, mental alertness, mood
- MeSH terms
- Adult, Affect, Central Nervous System Stimulants, Attention, Caffeine, Coffee, Dose-Response Relationship, Drug, Double-Blind Method, Drug Administration Schedule, Female, Humans, Male, Placebos, Psychomotor Performance, Surveys and Questionnaires, Reaction Time, Time Factors
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review