Cited by 104Neurotransmitter Receptor Influence on BehaviorRegulation of Appetite and ObesityNeuroendocrine regulation and behavior

Effects of isolation-rearing on voluntary consumption of ethanol, sucrose and saccharin solutions in Fawn Hooded and Wistar rats

Hall, F. S., Huang, S., Pert, A., Linnoila, M., Fong, G. W.·1998·Psychopharmacology

Abstract

These experiments examined the hypothesis that isolation-rearing and strain influence hedonic mechanisms. In experiment 1, voluntary consumption of ethanol and water was monitored in the home cage of Fawn Hooded (FH) and Wistar rats. FH rats were found to consume more ethanol at low concentrations than Wistar rats, independent of rearing condition, and isolation-reared rats were found to consume more of high ethanol concentrations, independent of strain. In experiment 2, isolation-reared rats were found to consume more sucrose, independent of concentration, than socially reared rats. In experiment 3, Fawn Hooded rats were found to be more sensitive to low concentration solutions of saccharin, and to consume less of the high concentration solutions, while isolation-rearing was found to enhance consumption of high concentrations. Thus, hedonic processes are independently modulated by strain and rearing conditions, although the effects of isolation-rearing appear to be exacerbated in Fawn Hooded rats.

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Crossref · 10.1007/s002130050706

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  • Adolescent but not adult social isolation increases alcohol consumption in mice.

    “In regard to alcohol use, adolescent but not adult, social isolation has been shown to increase alcohol consumption in mice (Lopez et al. 2011), and rats are well documented to increase their alcohol consumption after adolescent social isolation (Schenk et al. 1990; Hall et al. 1998; Chappell et al. 2013; reviewed further in Butler et al. 2016).”

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Authors
Hall, F. S., Huang, S., Pert, A., Linnoila, M., & Fong, G. W.
Affiliations
  • National Institutes of Health (US)
  • National Institute of Mental Health (US)
Venue
Psychopharmacology
Published
1998-09-09
Volume
139
Issue
3
Pages
210-216
ISSN
  • 0033-3158 (ISSN-L)
  • 1432-2072
OpenAlex
W1975207189
Cited by
104
References
0
Citations by year
2026: 3 · 2025: 4 · 2023: 2 · 2022: 3 · 2021: 2 · 2020: 4 · 2019: 3 · 2018: 4 · 2017: 5 · 2016: 9 · 2015: 5 · 2014: 8 · 2013: 6 · 2012: 2
FWCI
0.40
Type
journal article
Language
en
Open access
closed
Locations
  • Psychopharmacology (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neurotransmitter Receptor Influence on Behavior
  • Life Sciences › Neuroscience › Endocrine and Autonomic Systems › Regulation of Appetite and Obesity
  • Social Sciences › Psychology › Social Psychology › Neuroendocrine regulation and behavior
Keywords
isolation rearing, voluntary ethanol consumption, sucrose intake, saccharin consumption, Fawn-Hooded rats, Wistar rats, strain differences, social isolation, taste sensitivity
MeSH terms
Alcohol Drinking, Animals, Feeding Behavior, Male, Saccharin, Social Isolation, Sucrose, Rats, Wistar, Rats

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