Pre-excitatory pause in frontal eye field responses
Abstract
We report a new characteristic of the presaccadic activity of the neurons in the frontal eye field of macaque monkeys. A fraction of neurons exhibited a significant pause in discharge rate preceding the excitatory visual or movement-related response. This pre-excitatory pause, which has been observed in striate and extrastriate visual areas, may represent a resetting of neural activation for detailed visual processing or saccade preparation.
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Emergence of synchronous modulation, dimensionality collapse, and strong suppression locked to sensory stimulation are known neural correlates of top-down regulated attention and decision-making processes.
“Emergence of synchronous modulation (33, 34), dimensionality collapse (46), and strong suppression locked to sensory stimulation (47, 48) are known neural correlates of top–down regulated attention (35) and decision-making processes (3–5).”
From Neural correlates of perceptual decision-making in the primary somatosensory cortex (2026) · cites this paper as [47]
The dip in firing rate seems to mark the beginning of evidence accumulation.
“The dip, observed in other studies 2,12–14, seems to mark the beginning of evidence accumulation.”
From Decision-making with multiple alternatives (2008) · cites this paper as [13]
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“Emergence of synchronous modulation (33, 34), dimensionality collapse (46), and strong suppression locked to sensory stimulation (47, 48) are known neural correlates of top–down regulated attention (35) and decision-making processes (3–5).”
- Authors
- Sato, T., & Schall, J.
- Affiliations
- Vanderbilt University (US)
- Corresponding author
- Schall, Jeffrey
- Venue
- Experimental Brain Research
- Published
- 2001-07-01
- Volume
- 139
- Issue
- 1
- Pages
- 53-58
- ISSN
- 0014-4819 (ISSN-L)
- OpenAlex
- W2151621545
- Cited by
- 35
- References
- 45
- Citations by year
- 2026: 2 · 2024: 1 · 2022: 3 · 2018: 1 · 2015: 2 · 2013: 1 · 2012: 1
- FWCI
- 0.87
- Type
- journal article
- Language
- en
- Open access
- closed
- Licence
- www.springer.com/tdm (tdm)
- Locations
- Experimental Brain Research (publishedVersion)
- PubMed (publishedVersion)
- Funders
- National Eye Institute (R01 EY08890, P30-EY08126, R01EY008890, P30EY008126)
- Topics
- Life Sciences › Neuroscience › Cognitive Neuroscience › Visual perception and processing mechanisms
- Life Sciences › Neuroscience › Cognitive Neuroscience › Neural and Behavioral Psychology Studies
- Life Sciences › Neuroscience › Cognitive Neuroscience › Motor Control and Adaptation
- Keywords
- frontal eye field, saccade preparation, neuronal discharge rate, visual responses, macaque
- MeSH terms
- Action Potentials, Animals, Conditioning, Operant, Frontal Lobe, Macaca mulatta, Macaca radiata, Neural Inhibition, Neurons, Orientation, Photic Stimulation, Psychomotor Performance, Reaction Time, Saccades
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