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Cited by 128Heavy Metal Exposure and ToxicityEnvironmental Toxicology and EcotoxicologyTrace Elements in Health

The DOI matches its Crossref record; 73 of the 73 references it cites were found in a registry or an index.

Blood, Urine, and Sweat (BUS) Study: Monitoring and Elimination of Bioaccumulated Toxic Elements

Genuis, Stephen J., Birkholz, Detlef, Rodushkin, Ilia, Beesoon, Sanjay·2011·Archives of Environmental Contamination and Toxicology
DOI 10.1007/s00244-010-9611-5
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Abstract

There is limited understanding of the toxicokinetics of bioaccumulated toxic elements and their methods of excretion from the human body. This study was designed to assess the concentration of various toxic elements in three body fluids: blood, urine and sweat. Blood, urine, and sweat were collected from 20 individuals (10 healthy participants and 10 participants with various health problems) and analyzed for approximately 120 various compounds, including toxic elements. Toxic elements were found to differing degrees in each of blood, urine, and sweat. Serum levels for most metals and metalloids were comparable with those found in other studies in the scientific literature. Many toxic elements appeared to be preferentially excreted through sweat. Presumably stored in tissues, some toxic elements readily identified in the perspiration of some participants were not found in their serum. Induced sweating appears to be a potential method for elimination of many toxic elements from the human body. Biomonitoring for toxic elements through blood and/or urine testing may underestimate the total body burden of such toxicants. Sweat analysis should be considered as an additional method for monitoring bioaccumulation of toxic elements in humans.

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Crossref · 10.1007/s00244-010-9611-5

Cites

73 of 73 references verified0 citation errors · 0 not checkable

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Citations

Cites

Research works printed but not linked: 5

  1. Augsten K, Stein G (1988) Scanning electron-microscopy and x-ray-microanalysis investigation of aluminum deposition in samples from hemodialyzed patients. Trace Elements Med 5(2):55–59
  2. Buechner P, Neufeld S, Mausberg B (2004) Metallic lunch: an analysis of heavy metals in the Canadian diet. Environ Def Can, Toronto
  3. Emsley J (2001) Nature’s building block: an A-Z guide to the elements. Oxford University Press, New York
  4. Rodushkin I, Odman F (2001) Analysis of biological samples by double focusing ICP-MS. Transworld research network. Recent Dev Pure Appl Anal Chem 5:51–66
  5. Sears M, Bray R (2008) Toxic metals in Canadians and their environments: Exposures, health effects, and physician and public health management strategies. A scoping review. Clinical Research Grants Awarded in 2008 by the Canadian Institute for Health Research

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Metadata

Authors
Genuis, S. J., Birkholz, D., Rodushkin, I., & Beesoon, S.
Affiliations
  • University of Alberta (CA)
  • Luleå University of Technology (SE)
Corresponding author
Genuis, Stephen J.
ORCID
Venue
Archives of Environmental Contamination and Toxicology
Publisher
Springer Science and Business Media LLC
Published
2010-11-06
Volume
61
Issue
2
Pages
344-357
ISSN
  • 0090-4341 (ISSN-L)
  • 1432-0703
DOI
10.1007/s00244-010-9611-5
OpenAlex
W2144786108
Cited by
128
References
73
Citations by year
2026: 2 · 2025: 13 · 2024: 9 · 2023: 5 · 2022: 12 · 2021: 15 · 2020: 10 · 2019: 8 · 2018: 4 · 2017: 7 · 2016: 6 · 2015: 7 · 2014: 7 · 2013: 11 · 2012: 10
FWCI
5.62
Type
journal article
Language
en
Open access
closed
Licence
www.springer.com/tdm (tdm)
Locations
  • Archives of Environmental Contamination and Toxicology (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Physical Sciences › Environmental Science › Health, Toxicology and Mutagenesis › Heavy Metal Exposure and Toxicity
  • Physical Sciences › Environmental Science › Health, Toxicology and Mutagenesis › Environmental Toxicology and Ecotoxicology
  • Health Sciences › Nursing › Nutrition and Dietetics › Trace Elements in Health
Keywords
toxic elements, bioaccumulation, toxicokinetics, sweat analysis, urine, blood, biomonitoring, metalloids, excretion pathways, body burden, heavy metals
MeSH terms
Adult, Aged, Blood Chemical Analysis, Body Fluids, Cross-Sectional Studies, Environmental Exposure, Environmental Monitoring, Female, Humans, Male, Metals, Middle Aged, Sweat, Young Adult

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