Cited by 240Enzyme Production and CharacterizationSeaweed-derived Bioactive CompoundsPolysaccharides and Plant Cell Walls

Bioconversion of red seaweed galactans: a focus on bacterial agarases and carrageenases

Michel, Gurvan, Nyval-Collen, Pi, Barbeyron, Tristan, Czjzek, Mirjam, Helbert, William·2006·Applied Microbiology and Biotechnology

Abstract

Agars and carrageenans are 1,3-alpha-1,4-beta-galactans from the cell walls of red algae, substituted by zero (agarose), one (kappa-), two (iota-), or three (lambda-carrageenan) sulfate groups per disaccharidic monomer. Agars, kappa-, and iota-carrageenans auto-associate into crystalline fibers and are well known for their gelling properties, used in a variety of laboratory and industrial applications. These sulfated galactans constitute a crucial carbon source for a number of marine bacteria. These microorganisms secrete glycoside hydrolases specific for these polyanionic, insoluble polysaccharides, agarases and carrageenases. This article reviews the microorganisms involved in the degradation of agars and carrageenans, in their environmental and taxonomic diversity. We also present an overview on the biochemistry of the different families of galactanases. The structure-function relationships of the family GH16 beta-agarases and kappa-caraggeenases and of the family GH82 iota-carrageenases are discussed in more details. In particular, we examine how the active site topologies of these glycoside hydrolases influence their mode of action in heterogeneous phase. Finally, we discuss the next challenges in the basic and applied field of the galactans of red algae and of their related degrading microorganisms.

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Crossref · 10.1007/s00253-006-0377-7

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Authors
Michel, G., Nyval-Collen, P., Barbeyron, T., Czjzek, M., & Helbert, W.
Affiliations
Centre National de la Recherche Scientifique (FR)
Corresponding author
Helbert, William
Venue
Applied Microbiology and Biotechnology
Published
2006-06
Volume
71
Issue
1
Pages
23-33
ISSN
  • 0175-7598 (ISSN-L)
  • 1432-0614
OpenAlex
W2001030191
Cited by
240
References
110
Citations by year
2026: 8 · 2025: 4 · 2024: 10 · 2023: 13 · 2022: 12 · 2021: 10 · 2020: 12 · 2019: 10 · 2018: 16 · 2017: 18 · 2016: 11 · 2015: 12 · 2014: 14 · 2013: 21 · 2012: 15
FWCI
0.79
Type
journal article
Language
en
Open access
closed
Locations
  • Applied Microbiology and Biotechnology (publishedVersion)
  • PubMed (publishedVersion)
  • HAL (submittedVersion)
Topics
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Biotechnology › Enzyme Production and Characterization
  • Life Sciences › Agricultural and Biological Sciences › Aquatic Science › Seaweed-derived Bioactive Compounds
  • Life Sciences › Agricultural and Biological Sciences › Plant Science › Polysaccharides and Plant Cell Walls
Keywords
agarase, carrageenase, agar, carrageenan, marine bacteria, glycoside hydrolases, polysaccharide degradation, active site topology, structure-function relationship, sulfated polysaccharides, marine microbial diversity
MeSH terms
Agar, Rhodophyta, Bacteria, Bacterial Proteins, Binding Sites, Biodegradation, Environmental, Carrageenan, Galactans, Glycoside Hydrolases, Marine Biology, Models, Molecular, Seaweed, Structure-Activity Relationship, Sulfates

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