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Non-occlusive mesenteric ischemia: etiology, diagnosis, and interventional therapy
Abstract
Non-occlusive mesenteric ischemia (NOMI) compromises all forms of mesenteric ischemia with patent mesenteric arteries. It generally affects patients over 50 years of age suffering from myocardial infarction, congestive heart failure, aortic insufficiency, renal or hepatic disease and patients following cardiac surgery. Non-occlusive disease accounts for 20-30% of all cases of acute mesenteric ischemia with a mortality rate of the order of 50%. Acute abdominal pain may be the only early presenting symptom of mesenteric ischemia. Non-invasive imaging modalities, such as CT, MRI, and ultrasound, are able to evaluate the aorta and the origins of splanchnic arteries. Despite the technical evolution of those methods, selective angiography of mesenteric arteries is still the gold standard in diagnosing peripheral splanchnic vessel disease. In early non-occlusive mesenteric ischemia, as opposed to occlusive disease, there is no surgical therapy. It is known that mesenteric vasospasm persists even after correction of the precipitating event. Vasospasm frequently responds to direct intra-arterial vasodilator therapy, which is the only treatment that has been shown to be effective.
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“Frequently arterial vasospasm responds to this direct vasodilator treatment and occasionally within minutes[102].”
From Ischemic bowel disease in 2021. (2021) · cites this paper as [102]
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Metadata
- Authors
- Trompeter, M., Brazda, T., Remy, C. T., Vestring, T., & Reimer, P.
- Affiliations
- University of Freiburg (DE)
- Universitätsmedizin Göttingen (DE)
- ORCID
- Reimer, Peter
- Venue
- European Radiology
- Published
- 2001-12-21
- Volume
- 12
- Issue
- 5
- Pages
- 1179-1187
- ISSN
- 0938-7994 (ISSN-L)
- 1432-1084
- OpenAlex
- W2020547252
- Cited by
- 378
- References
- 27
- Citations by year
- 2026: 14 · 2025: 17 · 2024: 17 · 2023: 18 · 2022: 26 · 2021: 21 · 2020: 28 · 2019: 21 · 2018: 19 · 2017: 23 · 2016: 19 · 2015: 21 · 2014: 20 · 2013: 16 · 2012: 11
- FWCI
- 4.29
- Type
- journal article
- Language
- en
- Open access
- closed
- Licence
- www.springer.com/tdm (tdm)
- Locations
- European Radiology (publishedVersion)
- PubMed (publishedVersion)
- GRO (submittedVersion)
- Topics
- Health Sciences › Medicine › Surgery › Abdominal vascular conditions and treatments
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Aortic Thrombus and Embolism
- Health Sciences › Medicine › Surgery › Omental and Epiploic Conditions
- Keywords
- nonocclusive mesenteric ischemia, acute mesenteric ischemia, non-invasive imaging, CT angiography, magnetic resonance imaging, ultrasound, angiography, acute abdominal pain, myocardial infarction, cardiac surgery complications, mortality
- MeSH terms
- Angiography, Diagnosis, Differential, Humans, Ischemia, Magnetic Resonance Imaging, Mesenteric Arteries, Tomography, X-Ray Computed, Ultrasonography, Vasodilator Agents, Laser-Doppler Flowmetry
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