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Cited by 348Psychotherapy Techniques and ApplicationsAnxiety, Depression, Psychometrics, Treatment, Cognitive ProcessesTreatment of Major Depression

The DOI matches its Crossref record; 50 of the 50 references it cites were found in a registry or an index.

A systematic review of research findings on the efficacy of interpersonal therapy for depressive disorders

de Mello, M. Feijo, de Jesus Mari, J., Bacaltchuk, J., Verdeli, H., Neugebauer, R.·2005·European Archives of Psychiatry and Clinical Neuroscience
DOI 10.1007/s00406-004-0542-x
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Abstract

Objective Interpersonal psychotherapy (IPT) is a time-limited psychotherapy for major depression. The aim of this study is to summarize findings from controlled trials of the efficacy of IPT in the treatment of depressive spectrum disorders (DSD) using a meta-analytic approach.Methods Studies of randomized clinical trials of IPT efficacy were located by searching all available data bases from 1974 to 2002. The searches employed the following MeSH categories: Depression/ Depressive Disorder; Interpersonal therapy; Outcome/Adverse Effects/Efficacy; in the identified studies. The efficacy outcomes were: remission; clinical improvement; the difference in depressive symptoms between the two arms of the trial at endpoint, and no recurrence. Drop out rates were used as an index of treatment acceptability.Results Thirteen studies fulfilled inclusion criteria and four meta-analyses were performed. IPT was superior in efficacy to placebo in nine studies (Weight Mean Difference (WMD) - 3.57 [-5.9, -1.16]). The combination of IPT and medication did not show an adjunctive effect compared to medication alone for acute treatment (RR 0.78 [0.30, 2.04]), for maintenance treatment (RR 1.01 [0.81, 1.25]), or for prophylactic treatment (RR 0.70 [0.30, 1.65]). IPT was significantly better than CBT (WMD -2.16 [-4.16,-0.15]).Conclusion The efficacy of IPT proved to be superior to placebo, similar to medication and did not increase when combined with medication. Overall, IPT was more efficacious than CBT. Current evidence indicates that IPT is an efficacious psychotherapy for DSD and may be superior to some other manualized psychotherapies.

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Crossref · 10.1007/s00406-004-0542-x

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Research works printed but not linked: 2

  1. Mufson L,Moreau D,Weissman MM, Klerman GL (1993) Interpersonal therapy for depressed adolescents. New York, Guilford Press
  2. Weissman MM, Markowitz JC (1998) An Overview of Interpersonal Psychotherapy. Washington, D.C., American Psychiatric Press, pp 1?33

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Metadata

Authors
de Mello, M. F., de Jesus Mari, J., Bacaltchuk, J., Verdeli, H., & Neugebauer, R.
Affiliations
  • Universidade Federal de São Paulo (BR)
  • Columbia University (US)
  • New York State Psychiatric Institute (US)
ORCID
Verdeli, H.
Venue
European Archives of Psychiatry and Clinical Neuroscience
Publisher
Springer Science and Business Media LLC
Published
2004-11-12
Volume
255
Issue
2
Pages
75-82
ISSN
  • 0003-9373 (ISSN-L)
  • 0940-1334
  • 1433-8491
DOI
10.1007/s00406-004-0542-x
OpenAlex
W2038051420
Cited by
346
References
49
Citations by year
2026: 3 · 2025: 5 · 2024: 5 · 2023: 12 · 2022: 8 · 2021: 18 · 2020: 19 · 2019: 15 · 2018: 12 · 2017: 15 · 2016: 11 · 2015: 16 · 2014: 16 · 2013: 36 · 2012: 17
FWCI
2.15
Type
journal article
Language
en
Open access
closed
Licence
www.springer.com/tdm (tdm)
Locations
  • European Archives of Psychiatry and Clinical Neuroscience (publishedVersion)
  • PubMed (publishedVersion)
  • UNIFESP Institutional Repository (Universidade Federal de São Paulo) (submittedVersion)
Funders
Medical Center, University of Pittsburgh
Topics
  • Social Sciences › Psychology › Clinical Psychology › Psychotherapy Techniques and Applications
  • Social Sciences › Psychology › Experimental and Cognitive Psychology › Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
  • Health Sciences › Medicine › Pharmacology (medical) › Treatment of Major Depression
Keywords
interpersonal psychotherapy, depressive disorders, major depressive disorder, psychotherapy efficacy, placebo comparison, cognitive behavioral therapy, antidepressant combination therapy, maintenance therapy, prophylaxis, remission, treatment discontinuation, treatment acceptability
MeSH terms
Antidepressive Agents, Combined Modality Therapy, Depressive Disorder, Humans, Interpersonal Relations, Patient Acceptance of Health Care, Psychiatric Status Rating Scales, Psychotherapy

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