The DOI matches its Crossref record; 309 of the 309 references it cites were found in a registry or an index.
The peroxisome: an update on mysteries 2.0
Open accessAbstract
Peroxisomes are key metabolic organelles, which contribute to cellular lipid metabolism, e.g. the β-oxidation of fatty acids and the synthesis of myelin sheath lipids, as well as cellular redox balance. Peroxisomal dysfunction has been linked to severe metabolic disorders in man, but peroxisomes are now also recognized as protective organelles with a wider significance in human health and potential impact on a large number of globally important human diseases such as neurodegeneration, obesity, cancer, and age-related disorders. Therefore, the interest in peroxisomes and their physiological functions has significantly increased in recent years. In this review, we intend to highlight recent discoveries, advancements and trends in peroxisome research, and present an update as well as a continuation of two former review articles addressing the unsolved mysteries of this astonishing organelle. We summarize novel findings on the biological functions of peroxisomes, their biogenesis, formation, membrane dynamics and division, as well as on peroxisome–organelle contacts and cooperation. Furthermore, novel peroxisomal proteins and machineries at the peroxisomal membrane are discussed. Finally, we address recent findings on the role of peroxisomes in the brain, in neurological disorders, and in the development of cancer.
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Cited by
Jomova, K., Alomar, S. Y., Alwasel, S. H., Nepovimova, E., Kuca, K., & Valko, M. (2024) · Archives of Toxicology · doi:10.1007/s00204-024-03696-4 · Cited by 1,445
Plasticity of ether lipids promotes ferroptosis susceptibility and evasion
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Free Radical Properties, Source and Targets, Antioxidant Consumption and Health
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Self-citation
Metadata
- Authors
- Islinger, M., Voelkl, A., Fahimi, H. D., & Schrader, M.
- Venue
- Histochemistry and Cell Biology
- Published
- 2018-09-15
- Volume
- 150
- Issue
- 5
- Pages
- 443-471
- ISSN
- 0948-6143 (ISSN-L)
- 1432-119X
- OpenAlex
- W4205992121
- Cited by
- 283
- References
- 309
- FWCI
- 18.07
- Type
- journal article
- Language
- en
- Open access
- hybrid
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