Organelle interplay-peroxisome interactions in health and disease.
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Peroxisomes are multifunctional, dynamic, membrane‐bound organelles with important functions in cellular lipid metabolism, rendering them essential for human health and development. Important roles for peroxisomes in signaling and the fine‐tuning of cellular processes are emerging, which integrate them in a complex network of interacting cellular compartments. Like many other organelles, peroxisomes communicate through membrane contact sites. For example, peroxisomal growth, positioning, and lipid metabolism involves contacts with the endoplasmic reticulum (ER). Here, we discuss the most recent findings on peroxisome‐organelle interactions including peroxisome‐ER interplay at membrane contacts sites, and functional interplay with mitochondria, lysosomes, and lipid droplets in mammalian cells. We address tether proteins, metabolic cooperation, and the impact of peroxisome interactions on human health and disease.
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Fatty acid chain length is governed by a balance between elongation and degradation, a process thought to be regulated at ER-peroxisome contact sites.
“Fatty acid chain length is governed by a balance between elongation and degradation, a process thought to be regulated at ER–peroxisome contact sites (Wanders et al., 2018; Schrader et al., 2020).”
From The neurological pathology of peroxisomal ACBD5 deficiency – lessons from patients and mouse models (2025) · cites this paper as Schrader et al., 2020
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Cites
Membrane lipids: where they are and how they behave
van Meer, G., Voelker, D. R., & Feigenson, G. W. (2008) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm2330 · Cited by 7,157 · see citing works
Autophagy regulates lipid metabolism
Singh, R., Kaushik, S., Wang, Y., Xiang, Y., Novak, I., Komatsu, M., Tanaka, K., Cuervo, A. M., & Czaja, M. J. (2009) · Nature · doi:10.1038/nature07976 · Cited by 3,975 · see citing works
Dynamics and functions of lipid droplets
Olzmann, J. A., & Carvalho, P. (2019) · Nature Reviews Molecular Cell Biology · doi:10.1038/s41580-018-0085-z · Cited by 2,740 · see citing works
Decoding ALS: from genes to mechanism
Taylor, J. P., Brown, R. H., & Cleveland, D. W. (2016) · Nature · doi:10.1038/nature20413 · Cited by 2,047 · see citing works
Applying systems-level spectral imaging and analysis to reveal the organelle interactome
Valm, A. M., Cohen, S., Legant, W. R., Melunis, J., Hershberg, U., Wait, E., Cohen, A. R., Davidson, M. W., Betzig, E., & Lippincott-Schwartz, J. (2017) · Nature · doi:10.1038/nature22369 · Cited by 1,113 · see citing works
Functions of plasmalogen lipids in health and disease
Braverman, N. E., & Moser, A. B. (2012) · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · doi:10.1016/j.bbadis.2012.05.008 · Cited by 1,082 · see citing works
Peroxisomes are signaling platforms for antiviral innate immunity
Dixit, E., Boulant, S., Zhang, Y.-J., Lee, A. S., Odendall, C., Shum, B. O. V., Hacohen, N., Chen, Z.-J. J., Whelan, S. P. J., Fransen, M., et al. (2010) · Cell · doi:10.1016/j.cell.2010.04.018 · Cited by 848 · see citing works
Mesmin, B., Bigay, J., von Filseck, J. M., Lacas‐Gervais, S., Drin, G., & Antonny, B. (2013) · Cell · doi:10.1016/j.cell.2013.09.056 · Cited by 798 · see citing works
A Lethal Defect of Mitochondrial and Peroxisomal Fission
Waterham, H. R., Koster, J., van Roermund, C. W. T., Mooyer, P. A. W., Wanders, R. J. A., & Leonard, J. V. (2007) · New England Journal of Medicine · doi:10.1056/nejmoa064436 · Cited by 749 · see citing works
Zinser, E., Sperka-Gottlieb, C. D. M., Fasch, E.-V., Kohlwein, S. D., Paltauf, F., & Daum, G. (1991) · Journal of Bacteriology · doi:10.1128/jb.173.6.2026-2034.1991 · Cited by 705 · see citing works
Here, there, and everywhere: The importance of ER membrane contact sites
Wu, H., Carvalho, P., & Voeltz, G. K. (2018) · Science · doi:10.1126/science.aan5835 · Cited by 688 · see citing works
Stoica, R., Vos, K. J. D., Paillusson, S., Mueller, S., Sancho, R. M., Lau, K., Vizcay‐Barrena, G., Lin, W.-L., Xu, Y.-F., Lewis, J. M., et al. (2014) · Nature Communications · doi:10.1038/ncomms4996 · Cited by 623 · see citing works
A conserved ER targeting motif in three families of lipid binding proteins and in Opi1p binds VAP
Loewen, C. J. R., Roy, A., & Levine, T. P. (2003) · The EMBO Journal · doi:10.1093/emboj/cdg201 · Cited by 607 · see citing works
Fis1 and Bap31 bridge the mitochondria–ER interface to establish a platform for apoptosis induction
Iwasawa, R., Mahul‐Mellier, A., Datler, C., Pazarentzos, E., & Grimm, S. (2011) · The EMBO Journal · doi:10.1038/emboj.2010.346 · Cited by 520 · see citing works
Reevaluation of the pathways for the biosynthesis of polyunsaturated fatty acids.
Sprecher, H. W., Luthria, D. L., Mohammed, B. S., & Baykousheva, S. P. (1995) · Journal of Lipid Research · doi:10.1016/s0022-2275(20)41084-3 · Cited by 515 · see citing works
PIKE, L. J., Han, X., Chung, K.-N., & Gross, R. W. (2002) · Biochemistry · doi:10.1021/bi0156557 · Cited by 512 · see citing works
Very long-chain fatty acids: elongation, physiology and related disorders
Kihara, A. (2012) · The Journal of Biochemistry · doi:10.1093/jb/mvs105 · Cited by 441 · see citing works
Intracellular cholesterol transport
Liscum, L., & Munn, N. J. (1999) · Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids · doi:10.1016/s1388-1981(99)00043-8 · Cited by 419 · see citing works
Bridging the gap: Membrane contact sites in signaling, metabolism, and organelle dynamics
Prinz, W. A. (2014) · The Journal of Cell Biology · doi:10.1083/jcb.201401126 · Cited by 391 · see citing works
Newly born peroxisomes are a hybrid of mitochondrial and ER-derived pre-peroxisomes
Sugiura, A., Mattie, S., Prudent, J., & McBride, H. M. (2017) · Nature · doi:10.1038/nature21375 · Cited by 386 · see citing works
Phosphatidylethanolamine is a key regulator of membrane fluidity in eukaryotic cells
Dawaliby, R., Trubbia, C., Delporte, C., Noyon, C., Ruysschaert, J.-M., Van Antwerpen, P., & Govaerts, C. (2016) · Journal of Biological Chemistry · doi:10.1074/jbc.m115.706523 · Cited by 385 · see citing works
Cholesterol transport through lysosome-peroxisome membrane contacts.
Chu, B.-B., Liao, Y.-C., Qi, W., Xie, C., Du, X., Wang, J., Yang, H., Miao, H.-H., Li, B.-L., & Song, B.-L. (2015) · Cell · doi:10.1016/j.cell.2015.02.019 · Cited by 377 · see citing works
Dynamin-like protein 1 is involved in peroxisomal fission
Koch, A., Thiemann, M., Grabenbauer, M., Yoon, Y., McNiven, M. A., & Schrader, M. (2003) · Journal of Biological Chemistry · doi:10.1074/jbc.m211761200 · Cited by 374 · see citing works
Self-citationMarsh, D. (2007) · Biophysical Journal · doi:10.1529/biophysj.107.107938 · Cited by 369 · see citing works
Human disorders of peroxisome metabolism and biogenesis
Waterham, H. R., Ferdinandusse, S., & Wanders, R. J. A. (2015) · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research · doi:10.1016/j.bbamcr.2015.11.015 · Cited by 368 · see citing works
An intimate collaboration between peroxisomes and lipid bodies
Binns, D. D., Januszewski, T., Chen, Y., Hill, J., Markin, V. S., Zhao, Y., Gilpin, C. J., Chapman, K. D., Anderson, R. G. W., & Goodman, J. M. (2006) · The Journal of Cell Biology · doi:10.1083/jcb.200511125 · Cited by 367 · see citing works
Wanders, R. J. A., Waterham, H. R., & Ferdinandusse, S. (2016) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2015.00083 · Cited by 366 · see citing works
A Tether Is a Tether Is a Tether: Tethering at Membrane Contact Sites
Eisenberg‐Bord, M., Shai, N., Schuldiner, M., & Bohnert, M. (2016) · Developmental Cell · doi:10.1016/j.devcel.2016.10.022 · Cited by 364 · see citing works
The Peroxisome-Mitochondria Connection: How and Why?
Fransen, M., Lismont, C., & Walton, P. (2017) · International Journal of Molecular Sciences · doi:10.3390/ijms18061126 · Cited by 351 · see citing works
Biochemistry and genetics of inherited disorders of peroxisomal fatty acid metabolism
Veldhoven, P. P. V. (2010) · Journal of Lipid Research · doi:10.1194/jlr.r005959 · Cited by 328 · see citing works
Cohen, S., Valm, A. M., & Lippincott‐Schwartz, J. (2018) · Current Opinion in Cell Biology · doi:10.1016/j.ceb.2018.06.003 · Cited by 324 · see citing works
Shai, N., Yifrach, E., van Roermund, C. W. T., Cohen, N., Bibi, C., IJlst, L., Cavellini, L., Meurisse, J., Schuster, R., Zada, L., et al. (2018) · Nature Communications · doi:10.1038/s41467-018-03957-8 · Cited by 320 · see citing works
Docosahexaenoic acid (DHA): An essential nutrient and a nutraceutical for brain health and diseases
Sun, G. Y., Simonyi, Á., Fritsche, K. L., Chuang, D. Y., Hannink, M., Gu, Z., Greenlief, C. M., Yao, J. K., Lee, J. C., & Beversdorf, D. Q. (2017) · Prostaglandins Leukotrienes and Essential Fatty Acids · doi:10.1016/j.plefa.2017.03.006 · Cited by 311 · see citing works
A role for Fis1 in both mitochondrial and peroxisomal fission in mammalian cells
Koch, A., Yoon, Y., Bonekamp, N. A., McNiven, M. A., & Schrader, M. (2005) · Molecular Biology of the Cell · doi:10.1091/mbc.e05-02-0159 · Cited by 308 · see citing works
Self-citationEndoplasmic Reticulum–Plasma Membrane Contact Sites
Saheki, Y., & Camilli, P. V. D. (2017) · Annual Review of Biochemistry · doi:10.1146/annurev-biochem-061516-044932 · Cited by 298 · see citing works
The peroxisome: an update on mysteries 2.0
Islinger, M., Völkl, A., Fahimi, H. D., & Schrader, M. (2018) · Histochemistry and Cell Biology · doi:10.1007/s00418-018-1722-5 · Cited by 287 · see citing works
Self-citationPeroxisomal disorders: The single peroxisomal enzyme deficiencies
Wanders, R. J. A., & Waterham, H. R. (2006) · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research · doi:10.1016/j.bbamcr.2006.08.010 · Cited by 279 · see citing works
The peroxisome: an update on mysteries
Islinger, M., Grille, S., Fahimi, H. D., & Schrader, M. (2012) · Histochemistry and Cell Biology · doi:10.1007/s00418-012-0941-4 · Cited by 279 · see citing works
Self-citationVAPs and ACBD5 tether peroxisomes to the ER for peroxisome maintenance and lipid homeostasis.
Hua, R., Cheng, D., Coyaud, É., Freeman, S., Di Pietro, E., Wang, Y., Vissa, A., Yip, C. M., Fairn, G. D., Braverman, N., et al. (2017) · Journal of Cell Biology · doi:10.1083/jcb.201608128 · Cited by 279 · see citing works
Abu-Safieh, L., Alrashed, M., Anazi, S., Alkuraya, H., Khan, A. O., Al-Owain, M., Al-Zahrani, J., Al-Abdi, L., Hashem, M., Al-Tarimi, S., et al. (2013) · Genome Research · doi:10.1101/gr.144105.112 · Cited by 276 · see citing works
Bishop, W. R., & Bell, R. M. (1988) · Annual Review of Cell Biology · doi:10.1146/annurev.cb.04.110188.003051 · Cited by 270 · see citing works
Expression of PEX11β Mediates Peroxisome Proliferation in the Absence of Extracellular Stimuli
Schrader, M., Reuber, B. E., Morrell, J. C., Jimenez-Sanchez, G., Obie, C., Stroh, T. A., Valle, D., Schroer, T. A., & Gould, S. J. (1998) · Journal of Biological Chemistry · doi:10.1074/jbc.273.45.29607 · Cited by 266 · see citing works
Self-citationACBD5 and VAPB mediate membrane associations between peroxisomes and the ER
Costello, J. L., Castro, I. G., Hacker, C., Schrader, T. A., Metz, J., Zeuschner, D., Azadi, A. S., Godinho, L. F., Costina, V., Findeisen, P., et al. (2017) · The Journal of Cell Biology · doi:10.1083/jcb.201607055 · Cited by 251 · see citing works
Self-citationYeast peroxisomes multiply by growth and division
Motley, A. M., & Hettema, E. H. (2007) · The Journal of Cell Biology · doi:10.1083/jcb.200702167 · Cited by 247 · see citing works
The VAP protein family: from cellular functions to motor neuron disease
Lev, S., Benhalevy, D., Peretti, D., & Dahan, N. (2008) · Trends in Cell Biology · doi:10.1016/j.tcb.2008.03.006 · Cited by 233 · see citing works
Wiese, S., Gronemeyer, T., Ofman, R., Kunze, M., Grou, C. P., Almeida, J. A., Eisenacher, M., Stephan, C., Hayen, H., Schollenberger, L., et al. (2007) · Molecular & Cellular Proteomics · doi:10.1074/mcp.m700169-mcp200 · Cited by 231 · see citing works
The lipid droplet—a well-connected organelle
Gao, Q., & Goodman, J. M. (2015) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2015.00049 · Cited by 231 · see citing works
The ether lipid-deficient mouse: Tracking down plasmalogen functions
Gorgas, K., Teigler, A., Komljenovic, D., & Just, W. W. (2006) · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research · doi:10.1016/j.bbamcr.2006.08.038 · Cited by 231 · see citing works
Peroxisome‐mitochondria interplay and disease
Schrader, M., Costello, J. L., Godinho, L. F., & Islinger, M. (2015) · Journal of Inherited Metabolic Disease · doi:10.1007/s10545-015-9819-7 · Cited by 217 · see citing works
Self-citationRedox interplay between mitochondria and peroxisomes
Lismont, C., Nordgren, M., Van Veldhoven, P. P., & Fransen, M. (2015) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2015.00035 · Cited by 214 · see citing works
Kohlwein, S. D., Marten Veenhuis, A., & van der Klei, I. J. (2012) · Genetics · doi:10.1534/genetics.112.143362 · Cited by 213 · see citing works
Ferdinandusse, S., Denis, S. W., Mooijer, P. A. W., Zhang, Z., Reddy, J. K., Spector, A. A., & Wanders, R. J. A. (2001) · Journal of Lipid Research · doi:10.1016/s0022-2275(20)31527-3 · Cited by 210 · see citing works
Paltauf, F. (1994) · Chemistry and Physics of Lipids · doi:10.1016/0009-3084(94)90054-x · Cited by 208 · see citing works
Spastin tethers lipid droplets to peroxisomes and directs fatty acid trafficking through ESCRT-III
Chang, C.-L., Weigel, A. V., Ioannou, M. S., Pasolli, H. A., Xu, C. S., Peale, D. R., Shtengel, G., Freeman, M., Hess, H. F., Blackstone, C., et al. (2019) · Journal of Cell Biology · doi:10.1083/jcb.201902061 · Cited by 206 · see citing works
Lipid droplet and peroxisome biogenesis occur at the same ER subdomains
Joshi, A., Nebenfuehr, B., Choudhary, V., Satpute‐Krishnan, P., Levine, T. P., Golden, A., & Prinz, W. A. (2018) · Nature Communications · doi:10.1038/s41467-018-05277-3 · Cited by 204 · see citing works
Mitochondria-associated membranes as hubs for neurodegeneration
Krols, M., Isterdael, G. V., Asselbergh, B., Kremer, A., Lippens, S., Timmerman, V., & Janssens, S. (2016) · Acta Neuropathologica · doi:10.1007/s00401-015-1528-7 · Cited by 200 · see citing works
A different kind of love – lipid droplet contact sites
Schuldiner, M., & Bohnert, M. (2017) · Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids · doi:10.1016/j.bbalip.2017.06.005 · Cited by 198 · see citing works
The different facets of organelle interplay—an overview of organelle interactions
Schrader, M., Godinho, L. F., Costello, J. L., & Islinger, M. (2015) · Front. Cell Dev. Biol. · doi:10.3389/fcell.2015.00056 · Cited by 190 · see citing works
Self-citationFission and proliferation of peroxisomes
Schrader, M., Bonekamp, N. A., & Islinger, M. (2012) · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · doi:10.1016/j.bbadis.2011.12.014 · Cited by 189 · see citing works
Self-citationX-Linked Adrenoleukodystrophy: Pathogenesis and Treatment
Engelen, M., Kemp, S., & Poll-The, B.-T. (2014) · Current Neurology and Neuroscience Reports · doi:10.1007/s11910-014-0486-0 · Cited by 187 · see citing works
Shamseldin, H. E., Alshammari, M., Al-Sheddi, T., Salih, M. A., Alkhalidi, H., Kentab, A., Repetto, G. M., Hashem, M., & Alkuraya, F. S. (2012) · Journal of Medical Genetics · doi:10.1136/jmedgenet-2012-100836 · Cited by 182 · see citing works
Long-chain acyl-CoA esters in metabolism and signaling: Role of acyl-CoA binding proteins
Neess, D., Bek, S., Engelsby, H., Gallego, S. F., & Færgeman, N. J. (2015) · Progress in Lipid Research · doi:10.1016/j.plipres.2015.04.001 · Cited by 181 · see citing works
The protective role of plasmalogens in iron-induced lipid peroxidation
Sindelar, P. J., Guan, Z.-Z., Dallner, G., & Ernster, L. (1999) · Free Radical Biology and Medicine · doi:10.1016/s0891-5849(98)00221-4 · Cited by 181 · see citing works
Absence of peroxisomes in mouse hepatocytes causes mitochondrial and ER abnormalities†
Dirkx, R., Vanhorebeek, I., Martens, K., Schad, A., Grabenbauer, M., Fahimi, D., Declercq, P., Van Veldhoven, P. P., & Baes, M. (2005) · Hepatology · doi:10.1002/hep.20628 · Cited by 174 · see citing works
Lipid droplet–organelle interactions: emerging roles in lipid metabolism
Barbosa, A. D., Savage, D. B., & Siniossoglou, S. (2015) · Current Opinion in Cell Biology · doi:10.1016/j.ceb.2015.04.017 · Cited by 171 · see citing works
Mullineaux, P. M., Exposito-Rodriguez, M., Laissue, P. P., & Smirnoff, N. (2018) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2018.01.033 · Cited by 170 · see citing works
Interactomic study on interaction between lipid droplets and mitochondria
Pu, J., Ha, C. W., Zhang, S., Jung, J. P., Huh, W., & Liu, P. (2011) · Protein & Cell · doi:10.1007/s13238-011-1061-y · Cited by 160 · see citing works
Proliferation and fission of peroxisomes — An update
Schrader, M., Costello, J. L., Godinho, L. F., Azadi, A. S., & Islinger, M. (2015) · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research · doi:10.1016/j.bbamcr.2015.09.024 · Cited by 157 · see citing works
Self-citationClinical, biochemical, and mutational spectrum of peroxisomal acyl-coenzyme A oxidase deficiency
Ferdinandusse, S., Denis, S., Hogenhout, E. M., Koster, J., van Roermund, C. W. T., IJlst, L., Moser, A. B., Wanders, R. J. A., & Waterham, H. R. (2007) · Human Mutation · doi:10.1002/humu.20535 · Cited by 156 · see citing works
No peroxisome is an island — Peroxisome contact sites
Shai, N., Schuldiner, M., & Zalckvar, E. (2015) · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research · doi:10.1016/j.bbamcr.2015.09.016 · Cited by 155 · see citing works
Peroxisome-mediated metabolism is required for immune response to microbial infection
Di Cara, F., Sheshachalam, A., Braverman, N. E., Rachubinski, R. A., & Simmonds, A. J. (2017) · Immunity · doi:10.1016/j.immuni.2017.06.016 · Cited by 155 · see citing works
Peroxisomal acyl-CoA synthetases
Watkins, P. A., & Ellis, J. M. (2012) · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · doi:10.1016/j.bbadis.2012.02.010 · Cited by 144 · see citing works
Phytanic acid metabolism in health and disease
Wanders, R. J. A., Komen, J. C., & Ferdinandusse, S. (2011) · Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids · doi:10.1016/j.bbalip.2011.06.006 · Cited by 143 · see citing works
Identification of MOSPD2, a novel scaffold for endoplasmic reticulum membrane contact sites
Mattia, T. D., Wilhelm, L. P., Ikhlef, S., Wendling, C., Spehner, D., Nominé, Y., Giordano, F., Mathelin, C., Drin, G., Tomasetto, C., et al. (2018) · EMBO Reports · doi:10.15252/embr.201745453 · Cited by 138 · see citing works
Membrane curvature during peroxisome fission requires Pex11
Opaliński, Ł., Kiel, J. A. K. W., Williams, C., Marten Veenhuis, A., & van der Klei, I. J. (2010) · The EMBO Journal · doi:10.1038/emboj.2010.299 · Cited by 132 · see citing works
Buchert, R., Tawamie, H., Smith, C., Uebe, S., Innes, A. M., Al Hallak, B., Ekici, A. B., Sticht, H., Schwarze, B., Lamont, R. E., et al. (2014) · The American Journal of Human Genetics · doi:10.1016/j.ajhg.2014.10.003 · Cited by 132 · see citing works
Human dihydroxyacetonephosphate acyltransferase deficiency: A new peroxisomal disorder
Wanders, R. J. A., Schumacher, H., Heikoop, J. C., Schutgens, R. B. H., & Tager, J. M. (1992) · Journal of Inherited Metabolic Disease · doi:10.1007/bf02435984 · Cited by 131 · see citing works
Differential substrate specificities of human ABCD1 and ABCD2 in peroxisomal fatty acid β-oxidation
van Roermund, C. W. T., Visser, W. F., IJlst, L., Waterham, H. R., & Wanders, R. J. A. (2011) · Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids · doi:10.1016/j.bbalip.2010.11.010 · Cited by 128 · see citing works
Impaired membrane traffic in defective ether lipid biosynthesis
Thai, T.-P. (2001) · Human Molecular Genetics · doi:10.1093/hmg/10.2.127 · Cited by 127 · see citing works
Koch, J., Feichtinger, R. G., Freisinger, P., Pies, M., Schrödl, F., Iuso, A., Sperl, W., Mayr, J. A., Prokisch, H., & Haack, T. B. (2016) · Journal of Medical Genetics · doi:10.1136/jmedgenet-2015-103500 · Cited by 127 · see citing works
Park, H. G., Park, W. J., Kothapalli, K. S. D., & Brenna, J. T. (2015) · The FASEB Journal · doi:10.1096/fj.15-271783 · Cited by 124 · see citing works
Rat Liver Peroxisomes after Fibrate Treatment
Islinger, M., Luöers, G. H., Li, K. W., Loos, M., & Völkl, A. (2007) · Journal of Biological Chemistry · doi:10.1074/jbc.m610910200 · Cited by 121 · see citing works
Self-citationACBD5 deficiency causes a defect in peroxisomal very long-chain fatty acid metabolism
Ferdinandusse, S., Falkenberg, K. D., Koster, J., Mooyer, P. A., Jones, R., van Roermund, C. W. T., Pizzino, A., Schrader, M., Wanders, R. J. A., Vanderver, A., et al. (2017) · Journal of Medical Genetics · doi:10.1136/jmedgenet-2016-104132 · Cited by 120 · see citing works
Self-citationThe orchestra of lipid-transfer proteins at the crossroads between metabolism and signaling
Chiapparino, A., Maeda, K., Türei, D., Sáez-Rodríguez, J., & Gavin, A. (2015) · Progress in Lipid Research · doi:10.1016/j.plipres.2015.10.004 · Cited by 118 · see citing works
Peroxisomes are juxtaposed to strategic sites on mitochondria
Cohen, Y., Klug, Y. A., Dimitrov, L., Erez, Z., Chuartzman, S. G., Elinger, D., Yofe, I., Soliman, K., Gärtner, J., Thoms, S., et al. (2014) · Molecular BioSystems · doi:10.1039/c4mb00001c · Cited by 117 · see citing works
Signaling Organelles of the Innate Immune System
Kagan, J. C. (2012) · Cell · doi:10.1016/j.cell.2012.11.011 · Cited by 116 · see citing works
An ER‐peroxisome tether exerts peroxisome population control in yeast
Knoblach, B., Sun, X., Coquelle, N., Fagarasanu, A. D., Poirier, R. L., & Rachubinski, R. A. (2013) · The EMBO Journal · doi:10.1038/emboj.2013.170 · Cited by 116 · see citing works
Young, P. A., Senkal, C. E., Suchanek, A. L., Grevengoed, T. J., Lin, D. D., Zhao, L., Crunk, A. E., Klett, E. L., Füllekrug, J., Obeid, L. M., et al. (2018) · Journal of Biological Chemistry · doi:10.1074/jbc.ra118.004049 · Cited by 110 · see citing works
Lipid droplets as ubiquitous fat storage organelles in C. elegans
Zhang, S. O., Trimble, R., Guo, F., & Mak, H. Y. (2010) · BMC Cell Biology · doi:10.1186/1471-2121-11-96 · Cited by 109 · see citing works
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Raychaudhuri, S., & Prinz, W. A. (2008) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0808321105 · Cited by 108 · see citing works
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Costello, J. L., Castro, I. G., Camões, F., Schrader, T. A., McNeall, D., Yang, J., Giannopoulou, E., Gomes, S. R. A. M., Pogenberg, V., Bonekamp, N. A., et al. (2017) · Journal of Cell Science · doi:10.1242/jcs.200204 · Cited by 107 · see citing works
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Nazarko, T. Y., Ozeki, K., Till, A., Ramakrishnan, G., Lotfi, P., Yan, M., & Subramani, S. (2014) · Journal of Cell Biology · doi:10.1083/jcb.201307050 · Cited by 99 · see citing works
ACBD2/ECI2-Mediated Peroxisome-Mitochondria Interactions in Leydig Cell Steroid Biosynthesis
Fan, J., Li, X., Issop, L., Culty, M., & Papadopoulos, V. (2016) · Molecular Endocrinology · doi:10.1210/me.2016-1008 · Cited by 99 · see citing works
Coupling organelle inheritance with mitosis to balance growth and differentiation
Asare, A., Levorse, J. M., & Fuchs, E. V. (2017) · Science · doi:10.1126/science.aah4701 · Cited by 94 · see citing works
Organelle dynamics and dysfunction: A closer link between peroxisomes and mitochondria
Camões, F., Bonekamp, N. A., Delille, H. K., & Schrader, M. (2008) · Journal of Inherited Metabolic Disease · doi:10.1007/s10545-008-1018-3 · Cited by 91 · see citing works
Self-citationLin, C., Schuster, M., Guimarães, S., Ashwin, P., Schrader, M., Metz, J., Hacker, C., Gurr, S. J., & Steinberg, G. (2016) · Nature Communications · doi:10.1038/ncomms11814 · Cited by 90 · see citing works
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Delille, H. K., Agricola, B., Guimarães, S., Borta, H., Lüers, G. H., Fransen, M., & Schrader, M. (2010) · Journal of Cell Science · doi:10.1242/jcs.062109 · Cited by 89 · see citing works
Self-citationMembrane dynamics and organelle biogenesis—lipid pipelines and vesicular carriers
Stefan, C. J., Trimble, W. S., Grinstein, S., Drin, G., Reinisch, K. M., Camilli, P. V. D., Cohen, S., Valm, A. M., Lippincott‐Schwartz, J., Levine, T. P., et al. (2017) · BMC Biology · doi:10.1186/s12915-017-0432-0 · Cited by 89 · see citing works
Yagita, Y., Shinohara, K., Abe, Y., Nakagawa, K., Al-Owain, M., Alkuraya, F. S., & Fujiki, Y. (2017) · Journal of Biological Chemistry · doi:10.1074/jbc.m116.760090 · Cited by 85 · cited 4× · see citing works
“Further characterization of those and another patient revealed a peroxisome-based disorder with progressive leukodystrophy, ataxia, progressive microcephaly with facial dysmorphisms, in addition to retinal dystrophy.(14,87) In all cases, ACBD5 protein was absent due to a homozygous splice site mutation(86) or a delete…”
BackgroundInfluentialWalton, P. A., Brees, C., Lismont, C., Apanasets, O., & Fransen, M. (2017) · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research · doi:10.1016/j.bbamcr.2017.07.013 · Cited by 85 · see citing works
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Castro, I. G., Richards, D. M., Metz, J., Costello, J. L., Passmore, J. B., Schrader, T. A., Gouveia, A., Ribeiro, D., & Schrader, M. (2018) · Traffic · doi:10.1111/tra.12549 · Cited by 84 · see citing works
Self-citationExpanding the phenotypes of the Pro56SerVAPBmutation: Proximal SMA with dysautonomia
Marques, V. D., Barreira, A. A., Davis, M. B., Abou‐Sleiman, P. M., Silva, W. A., Zago, M. A., Sobreira, C., Fazan, V. P. S., & Marques, W. (2006) · Muscle & Nerve · doi:10.1002/mus.20657 · Cited by 84 · see citing works
Pascual‐Ahuir, A., Manzanares‐Estreder, S., & Proft, M. (2017) · Oxidative Medicine and Cellular Longevity · doi:10.1155/2017/9860841 · Cited by 83 · see citing works
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Williams, C., Opaliński, Ł., Landgraf, C., Costello, J. L., Schrader, M., Krikken, A. M., Knoops, K., Kram, A. M., Volkmer, R., & van der Klei, I. J. (2015) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1418736112 · Cited by 81 · see citing works
Self-citationHanada, K. (2018) · Journal of Lipid Research · doi:10.1194/jlr.r085324 · Cited by 81 · see citing works
Peeters, A., Shinde, A. B., Dirkx, R., Smet, J., Bock, K. D., Espeel, M., Vanhorebeek, I., Vanlander, A. V., Coster, R. V., Carmeliet, P., et al. (2014) · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research · doi:10.1016/j.bbamcr.2014.11.017 · Cited by 80 · see citing works
Peroxisomal ACBD4 interacts with VAPB and promotes ER-peroxisome associations
Costello, J. L., Castro, I. G., Schrader, T. A., Islinger, M., & Schrader, M. (2017) · Cell Cycle · doi:10.1080/15384101.2017.1314422 · Cited by 79 · see citing works
Self-citationPeroxisome Interactions and Cross-Talk with Other Subcellular Compartments in Animal Cells
Schrader, M., Grille, S., Fahimi, H. D., & Islinger, M. (2013) · Sub-cellular biochemistry/Subcellular biochemistry · doi:10.1007/978-94-007-6889-5_1 · Cited by 79 · see citing works
Self-citationTargeting of hFis1 to Peroxisomes Is Mediated by Pex19p
Delille, H. K., & Schrader, M. (2008) · Journal of Biological Chemistry · doi:10.1074/jbc.m803332200 · Cited by 72 · see citing works
Self-citationPIP4K2A regulates intracellular cholesterol transport through modulating PI(4,5)P2 homeostasis
Hu, A., Zhao, X., Tu, H., Xiao, T., Fu, T., Wang, Y., Liu, Y., Shi, X., Luo, J., & Song, B. (2018) · Journal of Lipid Research · doi:10.1194/jlr.m082149 · Cited by 72 · see citing works
Biogenesis of peroxisomes and mitochondria: linked by division
Delille, H. K., Alves, R. M. P., & Schrader, M. (2009) · Histochemistry and Cell Biology · doi:10.1007/s00418-009-0561-9 · Cited by 70 · see citing works
Self-citationPhospholipid transport protein function at organelle contact sites
Cockcroft, S., & Raghu, P. (2018) · Current Opinion in Cell Biology · doi:10.1016/j.ceb.2018.04.011 · Cited by 69 · see citing works
The VDAC2–BAK axis regulates peroxisomal membrane permeability
Hosoi, K.-I., Miyata, N., Mukai, S., Furuki, S., Okumoto, K., Cheng, E. H. Y., & Fujiki, Y. (2017) · The Journal of Cell Biology · doi:10.1083/jcb.201605002 · Cited by 67 · see citing works
Polyunsaturated fatty acid biosynthesis: a microsomal-peroxisomal process
Sprecher, H. W., & Chen, Q. (1999) · Prostaglandins Leukotrienes and Essential Fatty Acids · doi:10.1016/s0952-3278(99)80006-4 · Cited by 65 · see citing works
Thai, T.-P., Heid, H., Rackwitz, H., Hunziker, A., Gorgas, K., & Just, W. W. (1997) · FEBS Letters · doi:10.1016/s0014-5793(97)01495-6 · Cited by 63 · see citing works
Docosahexaenoic acid mediates peroxisomal elongation, a prerequisite for peroxisome division
Itoyama, A., Honsho, M., Abe, Y., Moser, A. B., Yoshida, Y., & Fujiki, Y. (2012) · Journal of Cell Science · doi:10.1242/jcs.087452 · Cited by 60 · see citing works
Phytanic acid activation in rat liver peroxisomes is catalyzed by long-chain acyl-CoA synthetase
Watkins, P. A., Howard, A. E., Gould, S. J., Avigan, J., & Mihalik, S. J. (1996) · Journal of Lipid Research · doi:10.1016/s0022-2275(20)37477-0 · Cited by 60 · see citing works
Wanders, R. J. A. (2013) · Sub-cellular biochemistry/Subcellular biochemistry · doi:10.1007/978-94-007-6889-5_2 · Cited by 58 · see citing works
Tower, R. J., Fagarasanu, A. D., Aitchison, J. D., & Rachubinski, R. A. (2011) · Molecular Biology of the Cell · doi:10.1091/mbc.e11-01-0084 · Cited by 57 · see citing works
Functional characterisation of peroxisomal β‐oxidation disorders in fibroblasts using lipidomics
Herzog, K., Pras‐Raves, M. L., Ferdinandusse, S., Vervaart, M. A. T., Luyf, A. C. M., van Kampen, A. H. C., Wanders, R. J. A., Waterham, H. R., & Vaz, F. M. (2018) · Journal of Inherited Metabolic Disease · doi:10.1007/s10545-017-0076-9 · Cited by 57 · see citing works
Association of isolated bovine kidney cortex peroxisomes with endoplasmic reticulum
Zaar, K., Völkl, A., & Fahimi, H. D. (1987) · Biochimica et Biophysica Acta (BBA) - Biomembranes · doi:10.1016/0005-2736(87)90321-x · Cited by 56 · see citing works
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Okumoto, K., Ono, T., Toyama, R., Shimomura, A., Nagata, A., & Fujiki, Y. (2017) · The Journal of Cell Biology · doi:10.1083/jcb.201708122 · Cited by 54 · see citing works
Peroxisomal motility and interaction with microtubules
Schrader, M., Thiemann, M., & Fahimi, H. D. (2003) · Microscopy Research and Technique · doi:10.1002/jemt.10326 · Cited by 52 · see citing works
Self-citationPex11mediates peroxisomal proliferation by promoting deformation of the lipid membrane
Yoshida, Y., Niwa, H., Honsho, M., Itoyama, A., & Fujiki, Y. (2015) · Biology Open · doi:10.1242/bio.201410801 · Cited by 49 · see citing works
Sharing the cell's bounty – organelle inheritance in yeast
Knoblach, B., & Rachubinski, R. A. (2015) · Journal of Cell Science · doi:10.1242/jcs.151423 · Cited by 47 · see citing works
Kleinecke, S., Richert, S., de Hoz, L., Brügger, B., Kungl, T., Asadollahi, E., Quintes, S., Blanz, J., McGonigal, R., Naseri, K., et al. (2017) · eLife · doi:10.7554/elife.23332 · Cited by 46 · see citing works
Cockcroft, S., & Garner, K. (2011) · Critical Reviews in Biochemistry and Molecular Biology · doi:10.3109/10409238.2010.538664 · Cited by 44 · see citing works
Simmen, T., & Tagaya, M. (2017) · Advances in experimental medicine and biology · doi:10.1007/978-981-10-4567-7_1 · Cited by 43 · see citing works
Bonekamp, N. A., Sampaio, P., de Abreu, F. V., Lüers, G. H., & Schrader, M. (2012) · Traffic · doi:10.1111/j.1600-0854.2012.01356.x · Cited by 38 · see citing works
Self-citationMulti-localized Proteins: The Peroxisome-Mitochondria Connection
Costello, J. L., Passmore, J. B., Islinger, M., & Schrader, M. (2018) · Sub-cellular biochemistry/Subcellular biochemistry · doi:10.1007/978-981-13-2233-4_17 · Cited by 38 · see citing works
Self-citationFis1 depletion in osteoarthritis impairs chondrocyte survival and peroxisomal and lysosomal function
Kim, D., Song, J., Kang, Y.-H., Park, S., Kim, Y.-I., Kwak, S., Lim, D., Park, R., Chun, C. H., Choe, S., et al. (2016) · Journal of Molecular Medicine · doi:10.1007/s00109-016-1445-9 · Cited by 37 · see citing works
Studies on the metabolic fate of n-3 polyunsaturated fatty acids
Ferdinandusse, S., Denis, S. W., Dacremont, G., & Wanders, R. J. A. (2003) · Journal of Lipid Research · doi:10.1194/jlr.m300223-jlr200 · Cited by 36 · see citing works
Mind the Organelle Gap – Peroxisome Contact Sites in Disease
Castro, I. G., Schuldiner, M., & Zalckvar, E. (2018) · Trends in Biochemical Sciences · doi:10.1016/j.tibs.2018.01.001 · Cited by 36 · see citing works
Su, J., Thomas, A. S., Grabietz, T., Landgraf, C., Volkmer, R., Marrink, . J., Williams, C., & Melo, M. N. (2018) · Biochimica et Biophysica Acta (BBA) - Biomembranes · doi:10.1016/j.bbamem.2018.02.029 · Cited by 32 · see citing works
Onsite GTP fuelling via DYNAMO1 drives division of mitochondria and peroxisomes
Imoto, Y., Abe, Y., Honsho, M., Okumoto, K., Ohnuma, M., Kuroiwa, H., Kuroiwa, T., & Fujiki, Y. (2018) · Nature Communications · doi:10.1038/s41467-018-07009-z · Cited by 32 · see citing works
Peroxisomes and their central role in metabolic interaction networks in humans.
Wanders, R. J. A., Waterham, H. R., & Ferdinandusse, S. (2018) · Subcellular Biochemistry · doi:10.1007/978-981-13-2233-4_15 · Cited by 31 · see citing works
Fransen, M., & Lismont, C. (2018) · Sub-cellular biochemistry/Subcellular biochemistry · doi:10.1007/978-981-13-2233-4_19 · Cited by 25 · see citing works
Phosphoinositide synthesis and degradation in isolated rat liver peroxisomes
Jeynov, B., Lay, D., Schmidt, F., Tahirović, S., & Just, W. W. (2006) · FEBS Letters · doi:10.1016/j.febslet.2006.09.058 · Cited by 24 · see citing works
Shinde, A. B., Baboota, R. K., Denis, S. W., Loizides‐Mangold, U., Peeters, A., Espeel, M., Malheiro, A. R., Riezman, H., Vinckier, S., Vaz, F. M., et al. (2017) · Mitochondrion · doi:10.1016/j.mito.2017.08.013 · Cited by 23 · see citing works
Mospd1, a new player in mesenchymal versus epidermal cell differentiation
Thaler, R., Rumpler, M., Spitzer, S. G., Klaushofer, K., & Varga, F. (2010) · Journal of Cellular Physiology · doi:10.1002/jcp.22595 · Cited by 22 · see citing works
Kanzawa, N., Shimozawa, N., Wanders, R. J. A., Ikeda, K., Murakami, Y., Waterham, H. R., Mukai, S., Fujita, M., Maeda, Y., Taguchi, R., et al. (2012) · Journal of Lipid Research · doi:10.1194/jlr.m021204 · Cited by 21 · see citing works
Effect of peroxisome proliferation on ether phospholipid biosynthesizing enzymes in rat liver
Hardeman, D., Zomer, H. W. M., Schutgens, R. B. H., Tager, J. M., & van den BOSCH, H. (1990) · International Journal of Biochemistry · doi:10.1016/0020-711x(90)90231-q · Cited by 21 · see citing works
Mitochondria–organelle contact sites: the plot thickens
Elbaz‐Alon, Y. (2017) · Biochemical Society Transactions · doi:10.1042/bst20160130 · Cited by 20 · see citing works
Unloosing the Gordian knot of peroxisome formation
Costello, J. L., & Schrader, M. (2018) · Current Opinion in Cell Biology · doi:10.1016/j.ceb.2018.02.002 · Cited by 19 · see citing works
Self-citationAssessing Heterogeneity of Peroxisomes: Isolation of Two Subpopulations from Rat Liver
Islinger, M., Abdolzade‐Bavil, A., Liebler, S. S., Weber, G., & Völkl, A. (2012) · Methods in molecular biology · doi:10.1007/978-1-61779-959-4_6 · Cited by 15 · see citing works
Self-citationDissecting Peroxisome-Mediated Signaling Pathways: A New and Exciting Research Field
Wang, B., Apanasets, O., Nordgren, M., & Fransen, M. (2014) · Springer eBooks · doi:10.1007/978-3-7091-1788-0_11 · Cited by 11 · see citing works
Clinical and biochemical characteristics of peroxisomal disorders: an update
Wanders, R. J. A., Barth, P. G., Schutgens, R. B. H., & Tager, J. M. (1994) · European Journal of Pediatrics · doi:10.1007/bf02138777 · Cited by 11 · see citing works
Sharing with your children: Mechanisms of peroxisome inheritance
Knoblach, B., & Rachubinski, R. A. (2015) · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research · doi:10.1016/j.bbamcr.2015.11.023 · Cited by 8 · see citing works
Peroxisome Motility Measurement and Quantification Assay
Metz, J., Castro, I. G., & Schrader, M. (2017) · BIO-PROTOCOL · doi:10.21769/bioprotoc.2536 · Cited by 8 · see citing works
Self-citationLuo, J., Liao, Y.-C., Xiao, J., & Song, B. (2017) · Methods in molecular biology · doi:10.1007/978-1-4939-6875-6_11 · Cited by 4 · see citing works
Spastin tethers lipid droplets to peroxisomes and directs fatty acid trafficking through ESCRT-III
Ranea‐Robles, P. (2019) · doi:10.1242/prelights.10288 · Cited by 3 · see citing works
Flagged first, then by citations
1 of the 152 references couldn’t be matched to a known paper.
Research works printed but not linked: 1
- [27]Novikoff AB, Shin W. The endoplasmic reticulum in the Golgi zone and its relations to microbodies, Golgi apparatus and autophagic vacuoles in rat liver cell. J Microscopie. 1964; 3: 187‐ 206.
Cited by
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Sies, H., Belousov, V. V., Chandel, N. S., Davies, M. J., Jones, D. P., Mann, G. E., Murphy, M. P., Yamamoto, M., & Winterbourn, C. (2022) · Nature Reviews Molecular Cell Biology · doi:10.1038/s41580-022-00456-z · Cited by 1,735 · see citing works
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Lismont, C., Revenco, I., & Fransen, M. (2019) · International Journal of Molecular Sciences · doi:10.3390/ijms20153673 · Cited by 206 · see citing works
Goshisht, M. K., Tripathi, N., Patra, G. K., & Chaskar, M. G. (2023) · Chemical Science · doi:10.1039/d3sc01036h · Cited by 145 · see citing works
Dorninger, F., Forss‐Petter, S., Wimmer, I., & Berger, J. (2020) · Neurobiology of Disease · doi:10.1016/j.nbd.2020.105061 · Cited by 139 · see citing works
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Glorieux, C., & Calderón, P. B. (2024) · Redox Biology · doi:10.1016/j.redox.2024.103404 · Cited by 87 · see citing works
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Silva, B. S. C., DiGiovanni, L. F., Kumar, R., Carmichael, R. E., Kim, P. K., & Schrader, M. (2020) · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research · doi:10.1016/j.bbamcr.2020.118800 · Cited by 81 · see citing works
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Chen, C., Li, J., Qin, X., & Wang, W. (2020) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2020.00512 · Cited by 37 · see citing works
Xie, J., Liu, M., Liu, H., Jin, Z., Guan, F., Ge, S., Yan, J., Zheng, M., Cai, D., & Liu, J. (2021) · Food & Function · doi:10.1039/d1fo02863d · Cited by 34 · see citing works
Systematic multi‐level analysis of an organelle proteome reveals new peroxisomal functions
Yifrach, E., Holbrook‐Smith, D., Bürgi, J., Othman, A., Eisenstein, M., van Roermund, C. W. T., Visser, W. F., Tirosh, A., Rudowitz, M., Bibi, C., et al. (2022) · Molecular Systems Biology · doi:10.15252/msb.202211186 · Cited by 33 · see citing works
Darwisch, W., von Spangenberg, M., Lehmann, J., Singin, Ö., Deubert, G., Kühl, S., Roos, J., Horstmann, H., Körber, C., Hoppe, S., et al. (2020) · Communications Biology · doi:10.1038/s42003-020-01442-x · Cited by 32 · see citing works
Self-citationResolving monocytes generated through TRAM deletion attenuate atherosclerosis
Geng, S., Zhang, Y., Yi, Z., Lu, R., & Li, L. (2021) · JCI Insight · doi:10.1172/jci.insight.149651 · Cited by 32 · see citing works
Regulation of lysosomes in skeletal muscle during exercise, disuse and aging
Moradi, N., Sanfrancesco, V. C., Champsi, S., & Hood, D. A. (2024) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2024.09.028 · Cited by 32 · see citing works
Kim, E. H., Jeon, S., Park, J. O., Ryu, J. H., Mobasheri, A., Matta, C., & Jin, E. (2025) · Experimental & Molecular Medicine · doi:10.1038/s12276-025-01481-6 · Cited by 31 · see citing works
The Role of Oxidative Stress in Periodontitis
Bullón, P., Giampieri, F., Bullón, B., & Battino, M. A. (2025) · Journal of Periodontal Research · doi:10.1111/jre.70016 · Cited by 32 · see citing works
Inherited disorders of complex lipid metabolism: A clinical review
Xiao, C., Rossignol, F., Vaz, F. M., & Ferreira, C. R. (2021) · Journal of Inherited Metabolic Disease · doi:10.1002/jimd.12369 · Cited by 31 · see citing works
Wang, M., Ding, Y.-Q., Hu, Y., Li, Z., Luo, W., Liu, P., & Li, Z. (2023) · Redox Biology · doi:10.1016/j.redox.2023.102652 · Cited by 31 · see citing works
Mah, C. Y., Nguyen, A. D. T., Niijima, T., Helm, M., Dehairs, J., Ryan, F. J., Ryan, N. K., Quek, L., Hoy, A. J., Don, A. S., et al. (2024) · British Journal of Cancer · doi:10.1038/s41416-023-02557-8 · Cited by 28 · see citing works
Colasuonno, F., Niceforo, A., Marioli, C., Fracassi, A., Stregapede, F., Massey, K., Tartaglia, M., Bertini, E., Compagnucci, C., & Moreno, S. (2020) · Oxidative Medicine and Cellular Longevity · doi:10.1155/2020/6821247 · Cited by 26 · see citing works
Rosy Beginnings: Studying Peroxisomes in Drosophila
Pridie, C., Ueda, K., & Simmonds, A. (2020) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2020.00835 · Cited by 21 · see citing works
Vascular Metabolism as Driver of Atherosclerosis: Linking Endothelial Metabolism to Inflammation
Dzobo, K. E., Hanford, K., & Kroon, J. (2021) · Immunometabolism · doi:10.20900/immunometab20210020 · Cited by 26 · see citing works
Lipid Droplets as Regulators of Metabolism and Immunity
Boucher, D. M., Vijithakumar, V., & Ouimet, M. I. (2021) · Immunometabolism · doi:10.20900/immunometab20210021 · Cited by 25 · see citing works
Controlling contacts—Molecular mechanisms to regulate organelle membrane tethering
Kors, S., Kurian, S. M., Costello, J. L., & Schrader, M. (2022) · BioEssays · doi:10.1002/bies.202200151 · Cited by 25 · see citing works
Self-citationDai, J., Li, Y., Kametani, F., Cui, X., Igarashi, Y., Huo, J., Miyahara, H., Mori, M., & Higuchi, K. (2021) · eLife · doi:10.7554/elife.63538 · Cited by 24 · see citing works
Calcium/calmodulin-dependent protein kinase kinase 2 regulates hepatic fuel metabolism
Stork, B. A., Dean, A. M., Ortiz, A. R., Saha, P., Putluri, N., Planas-Silva, M. D., Mahmud, I., Rajapakshe, K., Coarfa, C., Knapp, S., et al. (2022) · Molecular Metabolism · doi:10.1016/j.molmet.2022.101513 · Cited by 23 · see citing works
Peroxisomes contribute to intracellular calcium dynamics in cardiomyocytes and non-excitable cells
Sargsyan, Y., Bickmeyer, U., Gibhardt, C. S., Streckfuß‐Bömeke, K., Bogeski, I., & Thoms, S. (2021) · Life Science Alliance · doi:10.26508/lsa.202000987 · Cited by 22 · see citing works
Mammalian pexophagy at a glance
Bajdzienko, J., & Bremm, A. (2024) · Journal of Cell Science · doi:10.1242/jcs.259775 · Cited by 22 · see citing works
Microbiota mitochondria disorders as hubs for early age-related macular degeneration
Fehér, J., Élő, Á., István, L., Nagy, Z. Z., Radak, Z. O., Scuderi, G., Artico, M., & Kovács, I. (2022) · GeroScience · doi:10.1007/s11357-022-00620-5 · Cited by 19 · see citing works
Human Cytomegalovirus vMIA Inhibits MAVS Oligomerization at Peroxisomes in an MFF-Dependent Manner
Ferreira, A., Gouveia, A., Magalhães, A. C., Valença, I., Marques, M., Kagan, J. C., & Ribeiro, D. (2022) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2022.871977 · Cited by 19 · see citing works
Fission Impossible (?)—New Insights into Disorders of Peroxisome Dynamics
Carmichael, R. E., Islinger, M., & Schrader, M. (2022) · Cells · doi:10.3390/cells11121922 · Cited by 19 · see citing works
Self-citationDifferential roles for ACBD4 and ACBD5 in peroxisome-ER interactions and lipid metabolism.
Costello, J. L., Koster, J., Silva, B. S. C., Worthy, H. L., Schrader, T. A., Hacker, C., Passmore, J., Kuypers, F. A., Waterham, H. R., & Schrader, M. (2023) · Journal of Biological Chemistry · doi:10.1016/j.jbc.2023.105013 · Cited by 18 · see citing works
Self-citationFocus on Molecular Functions of Anti-Aging Deacetylase SIRT3
Nahálková, J. (2022) · Biochemistry (Moscow) · doi:10.1134/s0006297922010035 · Cited by 18 · see citing works
Meghnem, D., Leong, E. K., Pinelli, M., Marshall, J. S., & Cara, F. D. (2022) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2022.856243 · Cited by 17 · see citing works
Potential Involvement of Peroxisome in Multiple Sclerosis and Alzheimer’s Disease
Zarrouk, A., Nury, T., Hajj, H. I. E., Gondcaille, C., Andreoletti, P., Moreau, T., Cherkaoui‐Malki, M., Berger, J., Hammami, M., Lizard, G., et al. (2020) · Advances in experimental medicine and biology · doi:10.1007/978-3-030-60204-8_8 · Cited by 17 · see citing works
Peroxisomal defects in microglial cells induce a disease-associated microglial signature
Raas, Q., Tawbeh, A., Tahri-Joutey, M., Gondcaille, C., Keime, C., Kaiser, R., Trompier, D., Nasser, B., Leoni, V., Bellanger, E., et al. (2023) · Frontiers in Molecular Neuroscience · doi:10.3389/fnmol.2023.1170313 · Cited by 16 · see citing works
Control of mitochondrial dynamics and apoptotic pathways by peroxisomes
Jiang, C., & Okazaki, T. (2022) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2022.938177 · Cited by 16 · see citing works
Solymosi, K., & Schoefs, B. (2019) · Botany Letters · doi:10.1080/23818107.2019.1652851 · Cited by 16 · see citing works
Redox system and ROS-related disorders in peroxisomes
Kim, H., Hwang, J., Park, C., & Park, R. (2024) · Free Radical Research · doi:10.1080/10715762.2024.2427088 · Cited by 16 · see citing works
Biomedical Applications of Metal–Organic Frameworks at the Subcellular Level
Xue, J., Liu, J., Yong, J. M., & Liang, K. (2021) · Advanced NanoBiomed Research · doi:10.1002/anbr.202100034 · Cited by 15 · see citing works
Reglinski, K., Steinfort, L. L., Sezgin, E., Klose, C. D., Platta, H. W., Girzalsky, W., Eggeling, C., & Erdmann, R. (2020) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2020.574363 · Cited by 14 · see citing works
Peroxisomal membrane protein PMP70 confers drug resistance in colorectal cancer
Yin, J., Shao, Y., Huang, F., Hong, Y., Wei, W., Jiang, C., Zhao, Q., & Liu, L. (2025) · Cell Death and Disease · doi:10.1038/s41419-025-07572-6 · Cited by 13 · see citing works
Cheng, M., Wang, H.-H., Hua, M. D.-S., Kuo, H., Lin, Z.-J., Hsieh, C.-C., Hsu, C., Li, C., Wang, S., Chen, Y., et al. (2025) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2025.118126 · Cited by 13 · see citing works
Phillips, I. R., Veeravalli, S., Khadayate, S. P., & Shephard, E. A. (2023) · PLoS ONE · doi:10.1371/journal.pone.0286692 · Cited by 13 · see citing works
Fluorescent Tools to Analyze Peroxisome–Endoplasmic Reticulum Interactions in Mammalian Cells
Bishop, A., Kamoshita, M., Passmore, J. B., Hacker, C., Schrader, T. A., Waterham, H. R., Costello, J. L., & Schrader, M. (2019) · Contact · doi:10.1177/2515256419848641 · Cited by 13 · see citing works
Self-citationER-organelle contacts: A signaling hub for neurological diseases
Wang, Y., & Yang, J. (2024) · Pharmacological Research · doi:10.1016/j.phrs.2024.107149 · Cited by 11 · see citing works
Kors, S., Schuster, M., Maddison, D. C., Kilaru, S., Schrader, T. A., Costello, J. L., Islinger, M., Smith, G. A., & Schrader, M. (2024) · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research · doi:10.1016/j.bbamcr.2024.119843 · Cited by 12 · see citing works
Self-citationSharing the wealth: The versatility of proteins targeted to peroxisomes and other organelles
Bittner, E., Stehlik, T., & Freitag, J. (2022) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2022.934331 · Cited by 11 · see citing works
Wood, E. G., Macdougall, C. E., Blythe, H. C., Clément, M., Colas, R. A., Dalli, J., Marelli‐Berg, F. M., & Longhi, M. P. (2020) · Scientific Reports · doi:10.1038/s41598-020-77793-6 · Cited by 11 · see citing works
Li, L., Kan, W., Zhang, Y., Wang, T., Yang, F., Ji, T., Wang, G., & Du, J. (2024) · Translational Psychiatry · doi:10.1038/s41398-024-03127-z · Cited by 9 · see citing works
Peroxisomal core structures segregate diverse metabolic pathways
Bäcker, N., Ast, J., Martorana, D., Renicke, C. C., Berger, J., Mais, C.-N., Christ, M., Stehlik, T., Heimerl, T., Wernet, V., et al. (2025) · Nature Communications · doi:10.1038/s41467-025-57053-9 · Cited by 9 · see citing works
Peroxisome Dysfunction and Steatotic Liver Disease
Vinoy, N., Huang, G., Wallace, D. F., & Subramaniam, V. N. (2025) · International Journal of Molecular Sciences · doi:10.3390/ijms26178303 · Cited by 9 · see citing works
Lu, D., Wang, H., Shi, Y., Pan, T., Mei, Q., Li, B., Lee, L. P., & Xin, H. (2025) · ACS Nano · doi:10.1021/acsnano.5c13054 · Cited by 8 · see citing works
Gluing yeast peroxisomes – composition and function of membrane contact sites
Wu, F., de Boer, R., & van der Klei, I. J. (2023) · Journal of Cell Science · doi:10.1242/jcs.259440 · Cited by 8 · see citing works
Organellomics: AI-driven deep organellar phenotyping reveals novel ALS mechanisms in human neuronsPreprint
Krispin, S., van Zuiden, W., Danino, Y. M., Rudberg, N., Molitor, L., Abarbanel, B., Aviram, G., Wolf, G., Bar, C., Siani, A., et al. (2024) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2024.01.31.572110 · Cited by 8 · see citing works
The neurological pathology of peroxisomal ACBD5 deficiency – lessons from patients and mouse models
Dawes, M. L., Haberlander, J. P., Islinger, M., & Schrader, M. (2025) · Frontiers in Molecular Neuroscience · doi:10.3389/fnmol.2025.1602343 · Cited by 7 · see citing works
Self-citationLi, H., Lismont, C., Costa, C. F., Hussein, M. A. F., Baes, M. I., & Fransen, M. (2023) · Antioxidants · doi:10.3390/antiox12030613 · Cited by 7 · see citing works
Peroxisomes are underappreciated organelles hijacked by viruses
Villares, M., Espert, L., & Daussy, C. F. (2024) · Trends in Cell Biology · doi:10.1016/j.tcb.2024.11.006 · Cited by 6 · see citing works
Peroxisome dynamics and inter-organelle interactions in neuronal health and disease
Carmichael, R. E. (2025) · Frontiers in Molecular Neuroscience · doi:10.3389/fnmol.2025.1603632 · Cited by 6 · see citing works
Course, C. W., Lewis, P. A., Kotecha, S. J., Cousins, M., Hart, K., Heesom, K. J., Watkins, W. J., & Kotecha, S. (2024) · Scientific Reports · doi:10.1038/s41598-024-73704-1 · Cited by 6 · see citing works
Bacterial pathogens hijack host cell peroxisomes for replication vacuole expansion and integrity
Hossain, M. J., Romanov, K. A., Jian, J., Swaby, L. C., Bandyopadhyay, S., Guan, I., Thomas, S. M., Olive, A. J., & O’Connor, T. J. (2025) · Science Advances · doi:10.1126/sciadv.adr8005 · Cited by 6 · see citing works
The p97 ATPase and its adaptor UBXD8 maintain peroxisome pools by preventing pexophagy
Montes, I. D., Amirthagunanathan, S., Ganji, R., Paulo, J. A., Ahlstedt, B. A., Nguyen, L., Joshi, A. S., & Raman, M. (2025) · The Journal of Cell Biology · doi:10.1083/jcb.202409024 · Cited by 6 · see citing works
Douglas, T. D., Newby, L. K., Eckstrand, J., Wixted, D., & Singh, R. H. (2020) · Molecular Genetics and Metabolism Reports · doi:10.1016/j.ymgmr.2020.100651 · Cited by 6 · see citing works
Quantitative analysis of peroxisome tracks using a Hidden Markov Model
Svensson, C., Reglinski, K., Schliebs, W., Erdmann, R., Eggeling, C., & Figge, M. T. (2023) · Scientific Reports · doi:10.1038/s41598-023-46812-7 · Cited by 5 · see citing works
Distinct peroxisome populations differentially respond to alcohol-associated hepatic injury
Mitra, R., Adhikari, R., Davis, S. S., McVicker, B. L., & Tuma, P. L. (2024) · Molecular Biology of the Cell · doi:10.1091/mbc.e24-06-0252 · Cited by 5 · see citing works
Erban, T., Kadlečková, D., Sopko, B., Harant, K., Talacko, P., Markovic, M., Saláková, M., Kadlikova, K., Tachezy, R., & Tachezy, J. (2024) · PROTEOMICS · doi:10.1002/pmic.202300312 · Cited by 4 · see citing works
Interorganelle phospholipid communication, a house not so divided
Lee, R. G., Rudler, D. L., Rackham, O., & Filipovska, A. (2024) · Trends in Endocrinology and Metabolism · doi:10.1016/j.tem.2024.06.008 · Cited by 4 · see citing works
Correlation of organelle interactions in the development of non-alcoholic fatty liver disease
Liao, J., Shao, M., Ze, Z., Wang, S., Lv, Y., Lu, Y., Yao, F., Li, W., & Yang, L. (2025) · Frontiers in Immunology · doi:10.3389/fimmu.2025.1567743 · Cited by 4 · see citing works
Xu, X., Zhu, W., Miao, M., Bai, M., Fan, J., Niu, Y., Li, Y., Zhang, A., Jia, Z., & Wu, M. (2024) · Chinese Journal of Natural Medicines · doi:10.1016/s1875-5364(24)60608-4 · Cited by 4 · see citing works
PEX1G843D remains functional in peroxisome biogenesis but is rapidly degraded by the proteasome
Sheedy, C. J., Chowdhury, S. P., Ali, B. A., Miyamoto, J., Pang, E. Z., Bacal, J., Tavasoli, K. U., Richardson, C. D., & Gardner, B. M. (2025) · Journal of Biological Chemistry · doi:10.1016/j.jbc.2025.108467 · Cited by 4 · see citing works
The Function of the Peroxisome
Morita, M., & Imanaka, T. (2019) · Springer eBooks · doi:10.1007/978-981-15-1169-1_4 · Cited by 4 · see citing works
Lobo‐da‐Cunha, A., Alves, Â., Oliveira, E., & Calado, G. (2022) · Journal of Marine Science and Engineering · doi:10.3390/jmse10020160 · Cited by 4 · see citing works
Hanada, K. (2019) · Traffic · doi:10.1111/tra.12716 · Cited by 4 · see citing works
Current advances in the function and biogenesis of peroxisomes and their roles in health and disease
Dahan, N., Francisco, T., Falter, C., Rodrigues, T. A., Kalel, V. C., Kunze, M., Hansen, T., Schliebs, W., & Erdmann, R. (2021) · Histochemistry and Cell Biology · doi:10.1007/s00418-021-01982-1 · Cited by 4 · see citing works
Mitochondrial and peroxisomal fission in cortical neurogenesis
Robertson, G. L., Bodnya, C., & Gama, V. (2025) · The International Journal of Biochemistry & Cell Biology · doi:10.1016/j.biocel.2025.106774 · Cited by 3 · see citing works
The BCL-2 Family Proteins: Insights Into Their Mechanism of Action and Therapeutic Potential
van Delft, M. F., & Dewson, G. (2022) · Elsevier eBooks · doi:10.1016/b978-0-12-821618-7.00141-3 · Cited by 3 · see citing works
Investigating the Role of Peroxisomes in Regulating Breast Cancer Stem Cell Mechanisms
Simsek, D., Hassan, G. S., Sotgia, F., & Lisanti, M. P. (2025) · International Journal of Molecular Sciences · doi:10.3390/ijms262311389 · Cited by 2 · see citing works
Organelle contact sites in cancer cells
Celotti, I., Scavezzon, M., Toffanin, S., Ruzza, A., Vianello, F., Zaltron, E., Bastianello, C., Rossini, M., Severin, F., & Leanza, L. (2026) · Cell Death and Disease · doi:10.1038/s41419-026-08674-5 · Cited by 2 · see citing works
Peroxisomes : novel findings and future directions
Pedrosa, A. G., Reglinski, K., Lismont, C., Kors, S., Costello, J. L., Rodrigues, T. A., Marques, M., Linka, N., Argyriou, C., Weinhofer, I., et al. (2023) · Histochemistry and Cell Biology · doi:10.1007/s00418-023-02201-9 · Cited by 2 · see citing works
- Authors
- Schrader, M., Kamoshita, M., & Islinger, M.
- Affiliations
- University of Exeter (GB)
- Heidelberg University (DE)
- Corresponding author
- Schrader, Michael
- Venue
- Journal of Inherited Metabolic Disease
- Publisher
- Wiley
- Published
- 2019-04-16
- Volume
- 43
- Issue
- 1
- Pages
- 71-89
- ISSN
- 0141-8955 (ISSN-L)
- 1573-2665
- PMC
- PMC7041636
- OpenAlex
- W2921717028
- Cited by
- 149
- References
- 152
- Citations by year
- 2026: 17 · 2025: 20 · 2024: 35 · 2023: 13 · 2022: 25 · 2021: 13 · 2020: 18 · 2019: 8
- FWCI
- 1.86
- Type
- journal article
- Language
- en
- Open access
- hybrid
- doi.org
- Licence
- Locations
- Journal of Inherited Metabolic Disease (publishedVersion, cc-by)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- Open Research Exeter (University of Exeter) (acceptedVersion, cc-by)
- Figshare (submittedVersion)
- Funders
- University of Heidelberg
- Deutsche Forschungsgemeinschaft (397476530)
- University of Exeter
- Biotechnology and Biological Sciences Research Council (BB/R016844/1, BB/N01541X/1)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Cell Biology › Cellular transport and secretion
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Clinical Biochemistry › Metabolism and Genetic Disorders
- Health Sciences › Medicine › Epidemiology › Autophagy in Disease and Therapy
- Keywords
- peroxisomes, organelle interactions, membrane contact sites, endoplasmic reticulum, lipid metabolism, peroxisome biogenesis, inborn errors of metabolism
- MeSH terms
- Animals, Disease, Endoplasmic Reticulum, Health, Humans, Lysosomes, Membrane Proteins, Mitochondria, Organelles, Signal Transduction, Peroxisomes, Lipid Metabolism, Mitochondrial Membranes, Lipid Droplets
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