Long-term predictors of anxiety and depression in adult patients with asthma
Abstract
Background It is well established that anxiety and depression are associated with asthma, but there is limited evidence about the persistence of anxiety/depression in asthma. The aim of our study was to assess the long-term predictors of anxiety and depression in adult asthmatic patients.Methods A total of 90 adult asthma patients (63 women, age 18-50 years) with different levels of disease control (28 uncontrolled and 34 partially controlled) were assessed at baseline and at follow-up after 7 years for anxiety, depression and asthma control. The same work-up on both occasions included: demographics, living conditions, medical history (e.g. comorbidities, adherence and exacerbations), Hospital Anxiety and Depression Scale (HADS), Asthma Quality of Life Questionnaire (AQLQ), disease control and lung function. Persistence was defined as the HADS scores for anxiety and depression present at baseline and follow-up.Results The HADS results at follow-up visit showed 36 (40%) asthma patients with anxiety and 13 (14%) with depression, with the persistence of anxiety in 17 (19%) and of depression in 7 (8%) patients. Significant predictors of anxiety at follow-up were HADS and AQLQ results at baseline and several parameters of asthma control at follow-up (area under the curve AUC 0.917, 95% confidence interval CI 0.829-0.969, p < 0.001) and for depression AQLQ mood disorder domain, asthma control and lung function (AUC 0.947, 95% CI 0.870-0.986, p < 0.001).Conclusion Anxiety and depression persist over years in some patients with asthma. The association between mood disorders and asthma suggests potential mutual treatability.
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Mood disorders, depression, and anxiety cause deterioration of asthma symptoms, functional limitations, and more referrals to health care centers.
“mood disorders, depression, and anxiety cause deterioration of symptoms, functional limitations, and more referrals to health care centers (7).”
From The Effect of Group Acceptance and Commitment Therapy on the Management of Asthma: A Randomized Clinical Trial (2022) · cites this paper as [7]
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- Authors
- Labor, M., Labor, S., Jurić, I., Fijačko, V., Popović Grle, S., & Plavec, D.
- Affiliations
- Klinički bolnički centar Osijek (HR)
- Children's Hospital Srebrnjak (HR)
- Corresponding author
- Plavec, Davor
- Venue
- Wiener klinische Wochenschrift
- Published
- 2017-04-18
- Volume
- 129
- Issue
- 19-20
- Pages
- 665-673
- ISSN
- 0043-5325 (ISSN-L)
- 1613-7671
- OpenAlex
- W2606307546
- Cited by
- 11
- References
- 35
- Citations by year
- 2025: 1 · 2023: 3 · 2022: 1 · 2021: 1 · 2020: 1 · 2019: 2 · 2017: 2
- FWCI
- 1.02
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Wiener klinische Wochenschrift (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Physiology › Asthma and respiratory diseases
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Chronic Obstructive Pulmonary Disease (COPD) Research
- Keywords
- asthma, anxiety, depression, mood disorders, asthma control, asthma quality of life, lung function, disease control, long-term predictors, comorbidities
- MeSH terms
- Adolescent, Adult, Anxiety Disorders, Asthma, Depressive Disorder, Female, Follow-Up Studies, Forecasting, Humans, Longitudinal Studies, Male, Middle Aged, Quality of Life, Surveys and Questionnaires, Young Adult
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