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Cited by 380

The DOI matches its Crossref record; 21 of the 21 references it cites were found in a registry or an index.

SARS-CoV-2 can induce brain and spine demyelinating lesions

Open access
Zanin, Luca, Saraceno, Giorgio, Panciani, Pier Paolo, Renisi, Giulia, Signorini, Liana, Migliorati, Karol, Fontanella, Marco Maria·2020·Acta Neurochirurgica

Abstract

SARS-CoV-2 can attack the central nervous system in the early stages of infection. Headache, anosmia, and dysgeusia are common symptoms. Disturbance of consciousness and seizures can occur as complications in case of severe COVID-19. We described the case of a COVID-19 patient admitted for interstitial pneumonia and seizures. MRI showed newly diagnosed demyelinating lesions. High-dose steroid treatment allowed neurological and respiratory recovery. We speculated a delayed immune response induced by SARS-CoV-2. The virus may lead to a SIRS-like immune disorder or play a role of infective trigger. Prompt invasive treatment should be adopted to avoid hypoxic neurotoxicity and prevent CNS injuries.

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Metadata

Authors
Zanin, L., Saraceno, G., Panciani, P. P., Renisi, G., Signorini, L., Migliorati, K., & Fontanella, M. M.
Venue
Acta Neurochirurgica
Published
2020-05-04
Volume
162
Issue
7
Pages
1491-1494
ISSN
  • 0001-6268 (ISSN-L)
  • 0942-0940
OpenAlex
W3022814386
Cited by
380
References
21
FWCI
32.37
Type
journal article
Language
en
Open access
bronze

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CoChat. (2026). Citation check: SARS-CoV-2 can induce brain and spine demyelinating lesions. https://app.cochat.ai/papers/10.1007/s00701-020-04374-x
The paper
Zanin, L., Saraceno, G., Panciani, P. P., Renisi, G., Signorini, L., Migliorati, K., & Fontanella, M. M. (2020). SARS-CoV-2 can induce brain and spine demyelinating lesions. Acta Neurochirurgica. https://doi.org/10.1007/s00701-020-04374-x

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