Neurologic features in severe SARS-CoV-2 infection
Open accessAbstract
Neurologic Features in SARS-CoV-2 Infection In a consecutive series of 64 patients with Covid-19 and ARDS, 58 of whom underwent neurologic examination, severe agitation and corticospinal signs were...
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
Existing studies identifying patients with neurological complications across centres have largely been limited to two or three hospitals and restricted by geography and specialty, so they did not assess complications across the clinical spectrum.
“However, these studies have largely been limited to two or three hospitals and are restricted by both geography and specialty, therefore not assessing the neurological and neuropsychiatric complications of COVID-19 across the clinical spectrum of neurology, stroke or acute medicine, psychiatry, and intensive care.”
From Neurological and neuropsychiatric complications of COVID-19 in 153 patients: a UK-wide surveillance study (2020) · cites this paper as [11]
People in nursing homes or other institutional settings face higher risk of COVID-19 infection, abandonment, and mental health problems.
“institutionalized patients, such as those in a nursing care facility are at higher risk of acquiring COVID-19 infection, increased feelings of abandonment, as well as mental health problems [20,21].”
In COVID-19, a dysexecutive syndrome was described in one third of survivors.
“In COVID-19, a dysexecutive syndrome in a third of survivors was described (Helms et al., 2020)”
From Persistent psychopathology and neurocognitive impairment in COVID-19 survivors: effect of inflammatory biomarkers at three-month follow-up (2021) · cites this paper as Helms et al., 2020
COVID-19 may affect other major body organs, including renal, cardiovascular, and central nervous systems.
“subsequent reports showed that COVID-19 may also affect other major body organs, including renal, cardiovascular, and central nervous systems (CNS) [16, 125, 128].”
From Cognitive decline following acute viral infections: literature review and projections for post-COVID-19 (2022) · cites this paper as [128]
Most cases of COVID-associated neurological symptoms are CSF-RT-PCR-negative, including encephalopathic patients.
“SARS-CoV-2 RNA, however, is rarely identified in CSF samples of COVID-19 patients [158], and most cases of COVID-associated neurological symptoms are CSF-RT-PCR-negative, including encephalopathic patients [128, 137, 159].”
From Cognitive decline following acute viral infections: literature review and projections for post-COVID-19 (2022) · cites this paper as [128]
Human CSF samples have failed thus far to reveal CoV-2 RNA.
“In addition, human CSF samples have failed thus far to reveal CoV-2 RNA (73, 77), and autopsies from human patients have found that the brain contains the lowest levels of CoV-2 across organs sampled (78).”
From Non-neuronal expression of SARS-CoV-2 entry genes in the olfactory system suggests mechanisms underlying COVID-19-associated anosmia (2020) · cites this paper as [73]
Many neurological symptoms associated with CoV-2 infection, such as stroke or altered consciousness, are consistent with underlying vasculopathy.
“Multiple immunostaining studies reveal that ACE2 protein in the human brain is predominantly or exclusively expressed in vasculature (and specifically expressed within pericytes) (52, 53, 70), and many neurological symptoms associated with CoV-2 infection like stroke or altered consciousness are consistent with an underlying vasculopathy (71-76).”
From Non-neuronal expression of SARS-CoV-2 entry genes in the olfactory system suggests mechanisms underlying COVID-19-associated anosmia (2020) · cites this paper as [73]
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Cited by
Sorted by citations
Wiersinga, W. J., Rhodes, A., Cheng, A. C., Peacock, S. J., & Prescott, H. C. (2020) · JAMA · doi:10.1001/jama.2020.12839 · Cited by 4,609 · see citing works
Rogers, J. P., Chesney, E., Oliver, D., Pollak, T. A., McGuire, P., Fusar-Poli, P., Zandi, M. S., Lewis, G., & David, A. S. (2020) · The Lancet Psychiatry · doi:10.1016/s2215-0366(20)30203-0 · Cited by 2,407 · see citing works
Neurological associations of COVID-19
Ellul, M. A., Benjamin, L., Singh, B., Lant, S., Michael, B. D., Easton, A., Kneen, R., Defres, S., Sejvar, J., & Solomon, T. (2020) · The Lancet Neurology · doi:10.1016/s1474-4422(20)30221-0 · Cited by 2,156 · see citing works
How mental health care should change as a consequence of the COVID-19 pandemic
Moreno, C., Wykes, T., Galderisi, S., Nordentoft, M., Crossley, N., Jones, N., Cannon, M., Correll, C. U., Byrne, L., Carr, S., et al. (2020) · The Lancet Psychiatry · doi:10.1016/s2215-0366(20)30307-2 · Cited by 1,840 · see citing works
SARS-CoV-2 is associated with changes in brain structure in UK Biobank
Douaud, G., Lee, S., Alfaro-Almagro, F., Arthofer, C., Wang, C., McCarthy, P., Lange, F., Andersson, J. L. R., Griffanti, L., Duff, E., et al. (2022) · Nature · doi:10.1038/s41586-022-04569-5 · Cited by 1,646 · see citing works
Varatharaj, A., Thomas, N., Ellul, M. A., Davies, N. W. S., Pollak, T. A., Tenorio, E. L., Sultan, M., Easton, A., Breen, G., Zandi, M., et al. (2020) · The Lancet Psychiatry · doi:10.1016/s2215-0366(20)30287-x · Cited by 1,246 · see citing works
Neuropathology of patients with COVID-19 in Germany: a post-mortem case series
Matschke, J., Lütgehetmann, M., Hagel, C., Sperhake, J. P., Schröder, A. S., Edler, C., Mushumba, H., Fitzek, A., Allweiss, L., Dandri, M., et al. (2020) · The Lancet Neurology · doi:10.1016/s1474-4422(20)30308-2 · Cited by 1,300 · see citing works
Brann, D. H., Tsukahara, T., Weinreb, C., Lipovsek, M., Van den Berge, K., Gong, B., Chance, R., Macaulay, I. C., Chou, H.-J., Fletcher, R. B., et al. (2020) · Science Advances · doi:10.1126/sciadv.abc5801 · Cited by 1,198 · see citing works
Central nervous system involvement by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2)
Paniz‐Mondolfi, A., Bryce, C., Grimes, Z., Gordon, R. E., Reidy, J., Lednicky, J., Sordillo, E. M., & Fowkes, M. (2020) · Journal of Medical Virology · doi:10.1002/jmv.25915 · Cited by 975 · see citing works
Merkler, A. E., Parikh, N. S., Mir, S., Gupta, A., Kamel, H., Lin, E., Lantos, J., Schenck, E. J., Goyal, P., Bruce, S. S., et al. (2020) · JAMA Neurology · doi:10.1001/jamaneurol.2020.2730 · Cited by 940 · see citing works
Zubair, A. S., McAlpine, L. S., Gardin, T., Farhadian, S., Kuruvilla, D. E., & Spudich, S. (2020) · JAMA Neurology · doi:10.1001/jamaneurol.2020.2065 · Cited by 923 · see citing works
Dysregulation of brain and choroid plexus cell types in severe COVID-19
Yang, A. C., Kern, F., Losada, P. M., Agam, M. R., Maat, C. A., Schmartz, G. P., Fehlmann, T., Stein, J. A., Schaum, N., Lee, D. P., et al. (2021) · Nature · doi:10.1038/s41586-021-03710-0 · Cited by 620 · see citing works
Heneka, M. T., Golenbock, D., Latz, E., Morgan, D., & Brown, R. (2020) · Alzheimer's Research & Therapy · doi:10.1186/s13195-020-00640-3 · Cited by 555 · see citing works
Mazza, M. G., Palladini, M., De Lorenzo, R., Magnaghi, C., Poletti, S., Furlan, R., Ciceri, F., Rovere-Querini, P., & Benedetti, F. (2021) · Brain, Behavior, and Immunity · doi:10.1016/j.bbi.2021.02.021 · Cited by 513 · see citing works
“In COVID-19, a dysexecutive syndrome in a third of survivors was described (Helms et al., 2020), as well as cognitive dysfunction in sustained attention domain possibly linked to the underlying inflammatory processes measured with CRP (Zhou et al.”
SARS‐CoV‐2 targets neurons of 3D human brain organoids
Ramani, A., Müller, L., Ostermann, P. N., Gabriel, E., Abida‐Islam, P., Müller‐Schiffmann, A., Mariappan, A., Goureau, O., Gruell, H., Walker, A., et al. (2020) · The EMBO Journal · doi:10.15252/embj.2020106230 · Cited by 518 · see citing works
Brain MRI Findings in Severe COVID-19: A Retrospective Observational Study
Kremer, S., Lersy, F., de Sèze, J., Ferré, J.-C., Maamar, A., Carsin-Nicol, B., Collange, O., Bonneville, F., Adam, G., Martin-Blondel, G., et al. (2020) · Radiology · doi:10.1148/radiol.2020202222 · Cited by 460 · see citing works
Self-citationLifting the mask on neurological manifestations of COVID-19
Pezzini, A., & Padovani, A. (2020) · Nature Reviews Neurology · doi:10.1038/s41582-020-0398-3 · Cited by 447 · see citing works
Greene, C., Connolly, R., Brennan, D., Laffan, A., O’Keeffe, E., Zaporojan, L., O’Callaghan, J., Thomson, B., Connolly, E., Argue, R., et al. (2024) · Nature Neuroscience · doi:10.1038/s41593-024-01576-9 · Cited by 429 · see citing works
The neurobiology of long COVID
Monje, M., & Iwasaki, A. (2022) · Neuron · doi:10.1016/j.neuron.2022.10.006 · Cited by 415 · see citing works
Assessment of cognitive function in patients after COVID-19 infection
Becker, J. H., Lin, J. J., Doernberg, M., Stone, K., Navis, A., Festa, J. R., & Wisnivesky, J. P. (2021) · JAMA Network Open · doi:10.1001/jamanetworkopen.2021.30645 · Cited by 367 · see citing works
Miskowiak, K., Johnsen, S., Sattler, S., Nielsen, S., Kunalan, K., Rungby, J., Lapperre, T., & Porsberg, C. (2021) · European Neuropsychopharmacology · doi:10.1016/j.euroneuro.2021.03.019 · Cited by 365 · see citing works
Neurological Involvement in COVID-19 and Potential Mechanisms: A Review
Aghagoli, G., Gallo Marin, B., Katchur, N. J., Chaves-Sell, F., Asaad, W. F., & Murphy, S. A. (2021) · Neurocritical Care · doi:10.1007/s12028-020-01049-4 · Cited by 357 · see citing works
Kreye, J., Reincke, S. M., Kornau, H.-C., Sánchez-Sendin, E., Corman, V. M., Liu, H., Yuan, M., Wu, N. C., Zhu, X., Lee, C.-C. D., et al. (2020) · Cell · doi:10.1016/j.cell.2020.09.049 · Cited by 347 · see citing works
Brain MRI Findings in Patients in the Intensive Care Unit with COVID-19 Infection
Kandemirli, S. G., Dogan, L., Sarikaya, Z. T., Kara, S., Akinci, C., Kaya, D., Kaya, Y., Yildirim, D., Tuzuner, F., Yildirim, M. S., et al. (2020) · Radiology · doi:10.1148/radiol.2020201697 · Cited by 298 · see citing works
Hernández-Fernández, F., Sandoval Valencia, H., Barbella-Aponte, R. A., Collado-Jiménez, R., Ayo-Martín, Ó., Barrena, C., Molina-Nuevo, J. D., García-García, J., Lozano-Setién, E., Alcahut-Rodriguez, C., et al. (2020) · Brain · doi:10.1093/brain/awaa239 · Cited by 280 · see citing works
Spectrum of neuropsychiatric manifestations in COVID-19.
Nalleballe, K., Reddy Onteddu, S., Sharma, R., Dandu, V., Brown, A., Jasti, M., Yadala, S., Veerapaneni, K., Siddamreddy, S., Avula, A., et al. (2020) · Brain, Behavior, and Immunity · doi:10.1016/j.bbi.2020.06.020 · Cited by 235 · see citing works
Encephalopathy in patients with COVID‐19: A review
Garg, R. K., Paliwal, V. K., & Gupta, A. (2021) · Journal of Medical Virology · doi:10.1002/jmv.26207 · Cited by 224 · see citing works
Beach, S. R., Praschan, N. C., Hogan, C., Dotson, S., Merideth, F., Kontos, N., Fricchione, G. L., & Smith, F. A. (2020) · General Hospital Psychiatry · doi:10.1016/j.genhosppsych.2020.05.008 · Cited by 199 · see citing works
“thermore, while a test for detecting virus in the CSF has been described in other countries [2,7], such a test is not yet available in the United States.”
InfluentialCOVID-19 vasculitis and novel vasculitis mimics
McGonagle, D., Bridgewood, C., Ramanan, A. V., Meaney, J. F. M., & Watad, A. (2021) · The Lancet Rheumatology · doi:10.1016/s2665-9913(20)30420-3 · Cited by 192 · see citing works
The Effect of the COVID-19 Pandemic on People with Parkinson’s Disease
Brown, E. G., Chahine, L. M., Goldman, S. M., Korell, M., Mann, E., Kinel, D. R., Arnedo, V., Marek, K. L., & Tanner, C. M. (2020) · Journal of Parkinson's Disease · doi:10.3233/jpd-202249 · Cited by 177 · see citing works
Delorme, C., Paccoud, O., Kas, A., Hesters, A., Bombois, S., Shambrook, P., Boullet, A., Doukhi, D., Le Guennec, L., Godefroy, N., et al. (2020) · European Journal of Neurology · doi:10.1111/ene.14478 · Cited by 173 · see citing works
Neurological manifestations and COVID-19: Experiences from a tertiary care center at the Frontline
Pinna, P., Grewal, P., Hall, J. P., Tavarez, T., Dafer, R. M., Garg, R., Osteraas, N. D., Pellack, D. R., Asthana, A., Fegan, K., et al. (2020) · Journal of the Neurological Sciences · doi:10.1016/j.jns.2020.116969 · Cited by 169 · see citing works
Neurological and cognitive sequelae of COVID-19: a four month follow-up.
Mattioli, F., Stampatori, C., Righetti, F., Sala, E., Tomasi, C., & De Palma, G. (2021) · Journal of Neurology · doi:10.1007/s00415-021-10579-6 · Cited by 160 · see citing works
Tropism of SARS-CoV-2 for human cortical astrocytes
Andrews, M. G., Mukhtar, T., Eze, U. C., Simoneau, C. R., Ross, J., Parikshak, N., Wang, S., Zhou, L., Koontz, M., Velmeshev, D., et al. (2022) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2122236119 · Cited by 159 · see citing works
Cerebrospinal fluid findings in COVID-19 patients with neurological symptoms
Neumann, B., Schmidbauer, M. L., Dimitriadis, K., Otto, S., Knier, B., Niesen, W.-D., Hosp, J. A., Günther, A., Lindemann, S., Nagy, G., et al. (2020) · Journal of the Neurological Sciences · doi:10.1016/j.jns.2020.117090 · Cited by 155 · see citing works
Delirium: a missing piece in the COVID-19 pandemic puzzle
O’Hanlon, S., & Inouye, S. K. (2020) · Age and Ageing · doi:10.1093/ageing/afaa094 · Cited by 146 · see citing works
Negrini, F., Ferrario, I., Mazziotti, D., Berchicci, M., Bonazzi, M., de Sire, A., Negrini, S., & Zapparoli, L. (2021) · Archives of Physical Medicine and Rehabilitation · doi:10.1016/j.apmr.2020.09.376 · Cited by 121 · see citing works
Vieira, A. G. D. S., Pinto, A. C. P. N., Garcia, B. M. S. P., Eid, R. A. C., Mól, C. G., & Nawa, R. K. (2022) · Journal of Physiotherapy · doi:10.1016/j.jphys.2022.03.011 · Cited by 119 · see citing works
The looming storm: Blood and cytokines in COVID-19
Kaur, S., Bansal, R., Kollimuttathuillam, S., Gowda, A. M., Singh, B., Mehta, D., & Maroules, M. (2021) · Blood Reviews · doi:10.1016/j.blre.2020.100743 · Cited by 113 · see citing works
Speth, M. M., Singer‐Cornelius, T., Oberle, M., Gengler, I., Brockmeier, S. J., & Sedaghat, A. R. (2020) · The Laryngoscope · doi:10.1002/lary.28964 · Cited by 106 · see citing works
COVID-19: Review of a 21st Century Pandemic from Etiology to Neuro-psychiatric Implications
Yamamoto, V., Bolanos, J. F., Fiallos, J., Strand, S. E., Morris, K., Shahrokhinia, S., Cushing, T. R., Hopp, L., Tiwari, A., Hariri, R., et al. (2020) · Journal of Alzheimer's Disease · doi:10.3233/jad-200831 · Cited by 100 · see citing works
Damiano, R. F., Guedes, B. F., de Rocca, C. C., de Pádua Serafim, A., Castro, L. H. M., Munhoz, C. D., Nitrini, R., Filho, G. B., Miguel, E. C., Lucchetti, G., et al. (2022) · European Archives of Psychiatry and Clinical Neuroscience · doi:10.1007/s00406-021-01286-4 · Cited by 98 · see citing works
Systematic SARS-CoV-2 screening in cerebrospinal fluid during the COVID-19 pandemic
Destras, G., Bal, A., Escuret, V., Morfin, F., Lina, B., & Josset, L. (2020) · The Lancet Microbe · doi:10.1016/s2666-5247(20)30066-5 · Cited by 88 · see citing works
Prudencio, M., Erben, Y., Marquez, C. P., Jansen-West, K. R., Franco-Mesa, C., Heckman, M. G., White, L. J., Dunmore, J. A., Cook, C. N., Lilley, M. T., et al. (2021) · Science Translational Medicine · doi:10.1126/scitranslmed.abi7643 · Cited by 78 · see citing works
Greve, H. J., Dunbar, A. L., Lombo, C. G., Ahmed, C., Thang, M., Messenger, E. J., Mumaw, C. L., Johnson, J. A., Kodavanti, U. P., Oblak, A. L., et al. (2023) · Brain · doi:10.1093/brain/awac113 · Cited by 82 · see citing works
Battisti, N. M. L., Mislang, A. R., Cooper, L., O'Donovan, A., Audisio, R. A., Cheung, K.-L., Sarrió, R. G., Stauder, R., Soto-Perez-de-Celis, E., Jaklitsch, M., et al. (2020) · Journal of Geriatric Oncology · doi:10.1016/j.jgo.2020.07.008 · Cited by 79 · see citing works
Inflammatory leptomeningeal cytokines mediate COVID-19 neurologic symptoms in cancer patients
Remsik, J., Wilcox, J. A., Babady, N. E., McMillen, T. A., Vachha, B. A., Halpern, N. A., Dhawan, V., Rosenblum, M., Iacobuzio-Donahue, C. A., Avila, E. K., et al. (2021) · Cancer Cell · doi:10.1016/j.ccell.2021.01.007 · Cited by 77 · see citing works
Investigating Ketone Bodies as Immunometabolic Countermeasures against Respiratory Viral Infections
Stubbs, B. J., Koutnik, A. P., Goldberg, E. L., Upadhyay, V., Turnbaugh, P. J., Verdin, E., & Newman, J. C. (2020) · Med · doi:10.1016/j.medj.2020.06.008 · Cited by 71 · see citing works
Potential mechanisms of hemorrhagic stroke in elderly COVID-19 patients
Wang, H., Tang, X., Fan, H., Luo, Y., Song, Y., Xu, Y., & Chen, Y. (2020) · Aging · doi:10.18632/aging.103335 · Cited by 69 · see citing works
ICU Survivorship—The Relationship of Delirium, Sedation, Dementia, and Acquired Weakness
Mart, M. F., Pun, B. T., Pandharipande, P., Jackson, J. C., & Ely, E. W. (2021) · Critical Care Medicine · doi:10.1097/ccm.0000000000005125 · Cited by 67 · see citing works
Wood, G. K., Sargent, B. F., Ahmad, Z.-U.-A., Tharmaratnam, K., Dunai, C., Egbe, F. N., Martin, N. H., Facer, B., Pendered, S. L., Rogers, H. C., et al. (2025) · Nature Medicine · doi:10.1038/s41591-024-03309-8 · Cited by 67 · see citing works
Immunological defense of CNS barriers against infections
Ampie, L., & McGavern, D. B. (2022) · Immunity · doi:10.1016/j.immuni.2022.04.012 · Cited by 63 · see citing works
Amyloid processing in <scp>COVID</scp>‐19‐associated neurological syndromes
Ziff, O. J., Ashton, N. J., Mehta, P. R., Brown, R., Athauda, D., Heaney, J., Heslegrave, A. J., Benedet, A. L., Blennow, K., Checkley, A. M., et al. (2022) · Journal of Neurochemistry · doi:10.1111/jnc.15585 · Cited by 54 · see citing works
COVID-19 encephalopathy: detection of antibodies against SARS-CoV-2 in CSF
Andriuta, D., Roger, P.-A., Thibault, W., Toublanc, B., Sauzay, C., Castelain, S., Godefroy, O., & Brochot, E. (2020) · Journal of Neurology · doi:10.1007/s00415-020-09975-1 · Cited by 59 · see citing works
Iqbal, Y., Al Abdulla, M. A., Albrahim, S., Latoo, J., Kumar, R., & Haddad, P. M. (2020) · BJPsych Open · doi:10.1192/bjo.2020.85 · Cited by 53 · see citing works
Gomes, I. C., Karmirian, K., Oliveira, J., Pedrosa, C., Rosman, F. C., Chimelli, L., & Rehen, S. (2020) · doi:10.20944/preprints202009.0297.v1 · Cited by 51 · see citing works
Rabinovitz, B., Jaywant, A., & Fridman, C. B. (2020) · The Clinical Neuropsychologist · doi:10.1080/13854046.2020.1803408 · Cited by 46 · see citing works
COVID-19 as a Risk Factor for Alzheimer’s Disease
Golzari-Sorkheh, M., Weaver, D. F., & Reed, M. A. (2023) · Journal of Alzheimer's Disease · doi:10.3233/jad-220800 · Cited by 39 · see citing works
Imaging Features of Acute Encephalopathy in Patients with COVID-19: A Case Series
Kihira, S., Delman, B. N., Belani, P., Stein, L., Aggarwal, A., Rigney, B., Schefflein, J., Doshi, A. H., & Pawha, P. S. (2020) · American Journal of Neuroradiology · doi:10.3174/ajnr.a6715 · Cited by 38 · see citing works
Role of Dendritic Cells in Viral Brain Infections
Constant, O., Maarifi, G., Blanchet, F. P., Van de Perre, P., Simonin, Y., & Salinas, S. (2022) · Frontiers in Immunology · doi:10.3389/fimmu.2022.862053 · Cited by 35 · see citing works
Clinical, cerebrospinal fluid and neuroimaging findings in COVID-19 encephalopathy: a case series
Tuma, R., Guedes, B., Carra, R., Iepsen, B., Rodrigues, J., Camelo-Filho, A. E., Kubota, G., Ferrari, M., Neto, A. S., Oku, M. H. M., et al. (2020) · doi:10.1101/2020.08.28.20181883 · Cited by 26 · see citing works
Biomarkers of Neurological Damage: From Acute Stage to Post-Acute Sequelae of COVID-19
Zingaropoli, M. A., Pasculli, P., Barbato, C., Petrella, C., Fiore, M., Dominelli, F., Latronico, T., Ciccone, F., Antonacci, M., Liuzzi, G. M., et al. (2023) · Cells · doi:10.3390/cells12182270 · Cited by 16 · see citing works
Pneumatosis Intestinalis in the Setting of COVID-19: A Single Center Case Series From New York
Miyara, S. J., Becker, L. B., Guevara, S., Kirsch, C., Metz, C. N., Shoaib, M., Grodstein, E., Nair, V. V., Jandovitz, N., McCann-Molmenti, A., et al. (2021) · Frontiers in Medicine · doi:10.3389/fmed.2021.638075 · Cited by 9 · see citing works
Saxena, S., & Hashmi, A. Z. (2021) · Cleveland Clinic Journal of Medicine · doi:10.3949/ccjm.88a.ccc080 · Cited by 6 · see citing works
- Authors
- Helms, J., Kremer, S., Merdji, H., Clere-Jehl, R., Schenck, M., Kummerlen, C., Collange, O., Boulay, C., Fafi-Kremer, S., Ohana, M., Anheim, M., & Meziani, F.
- Affiliations
- Hôpitaux Universitaires de Strasbourg (FR)
- Laboratoire des Sciences de l'Ingénieur, de l'Informatique et de l'Imagerie (FR)
- Strasbourg University Hospital, Strasbourg, France
- Institut de génétique et de biologie moléculaire et cellulaire (FR)
- Regenerative NanoMedicine (FR)
- Corresponding author
- Meziani, Ferhat
- ORCID
- Venue
- New England Journal of Medicine
- Publisher
- Massachusetts Medical Society
- Published
- 2020-06-04
- Volume
- 382
- Issue
- 23
- Pages
- 2268-2270
- ISSN
- 0028-4793 (ISSN-L)
- 1533-4406
- PMC
- PMC7179967
- OpenAlex
- W3015925195
- Cited by
- 2,674
- References
- 0
- Citations by year
- 2026: 38 · 2025: 77 · 2024: 160 · 2023: 271 · 2022: 508 · 2021: 793 · 2020: 822 · 2019: 1 · 2018: 1 · 2012: 2
- FWCI
- 260.28
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- New England Journal of Medicine (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- HAL (submittedVersion)
- Topics
- Health Sciences › Medicine › Neurology › Long-Term Effects of COVID-19
- Health Sciences › Medicine › Infectious Diseases › COVID-19 Clinical Research Studies
- Health Sciences › Medicine › Infectious Diseases › Infectious Encephalopathies and Encephalitis
- Keywords
- COVID-19 pandemic, SARS-CoV-2, neurological complications, acute respiratory distress syndrome, agitation, neurological examination
- MeSH terms
- Betacoronavirus, COVID-19, SARS-CoV-2, Adult, Aged, Brain, Brain Diseases, Confusion, Humans, Magnetic Resonance Imaging, Middle Aged, Pneumonia, Viral, Respiratory Distress Syndrome, Coronavirus Infections, Reverse Transcriptase Polymerase Chain Reaction, Stroke, Pandemics
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
