The DOI matches its Crossref record; 76 of the 76 references it cites were found in a registry or an index.
The role of methionine on metabolism, oxidative stress, and diseases
Abstract
Methionine is an aliphatic, sulfur-containing, essential amino acid, and a precursor of succinyl-CoA, homocysteine, cysteine, creatine, and carnitine. Recent research has demonstrated that methionine can regulate metabolic processes, the innate immune system, and digestive functioning in mammals. It also intervenes in lipid metabolism, activation of endogenous antioxidant enzymes such as methionine sulfoxide reductase A, and the biosynthesis of glutathione to counteract oxidative stress. In addition, methionine restriction prevents altered methionine/transmethylation metabolism, thereby decreasing DNA damage and carcinogenic processes and possibly preventing arterial, neuropsychiatric, and neurodegenerative diseases. This review focuses on the role of methionine in metabolism, oxidative stress, and related diseases.
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“Banana peel has high carbon content and can be used as an absorbent to remove various pollutants from savage water [24, 25].”
From Functional, nutritional and medicinal potential of banana peel (2023) · cites this paper as [24]
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Zhang, Y., Roh, Y. J., Han, S.-J., Park, I., Lee, H. M., Ok, Y. S., Lee, B. C., & Lee, S.-R. (2020) · Antioxidants · doi:10.3390/antiox9050383 · Cited by 267
Metadata
- Authors
- Martínez, Y., Li, X., Liu, G., Bin, P., Yan, W., Más, D., Valdivié, M., Hu, C.-A. A., Ren, W., & Yin, Y.
- Affiliations
- Chinese Academy of Sciences (CN)
- University of New Mexico (US)
- Hunan Normal University (CN)
- Corresponding author
- Liu, Gang
- Venue
- Amino Acids
- Published
- 2017-09-19
- Volume
- 49
- Issue
- 12
- Pages
- 2091-2098
- ISSN
- 0939-4451 (ISSN-L)
- 1438-2199
- OpenAlex
- W2754863196
- Cited by
- 583
- References
- 76
- Citations by year
- 2026: 66 · 2025: 93 · 2024: 89 · 2023: 92 · 2022: 80 · 2021: 56 · 2020: 56 · 2019: 32 · 2018: 15 · 2017: 2
- FWCI
- 4.63
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Amino Acids (publishedVersion)
- PubMed (publishedVersion)
- Funders
- International Partnership Program of Chinese Academy of Sciences (161343KYSB20160008)
- National Key Research and Development Program of China (2016YFD0500504)
- National Natural Science Foundation of China (31570114, 31330075, 31110103909)
- Chinese Academy of Sciences visiting professorship for senior international scientists (2016VBB007)
- Topics
- Health Sciences › Nursing › Nutrition and Dietetics › Folate and B Vitamins Research
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Biochemistry › Sulfur Compounds in Biology
- Health Sciences › Medicine › Physiology (medical) › Biochemical effects in animals
- Keywords
- methionine, methionine metabolism, oxidative stress, methionine restriction, transmethylation, homocysteine, MsrA, glutathione synthesis, antioxidant enzymes, lipid metabolism, innate immunity, DNA damage, carcinogenesis, neurodegenerative diseases, cardiovascular disease, neuropsychiatric disorders
- MeSH terms
- Animals, Cardiovascular Diseases, Humans, Immunity, Innate, Kidney Diseases, Liver Diseases, Methionine, Neoplasms, Nervous System Diseases, Oxidative Stress, Lipid Metabolism
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