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Cited by 377

The DOI matches its Crossref record; 89 of the 89 references it cites were found in a registry or an index.

3D Printing of Calcium Phosphate Ceramics for Bone Tissue Engineering and Drug Delivery

Open access
Trombetta, Ryan, Inzana, Jason A., Schwarz, Edward M., Kates, Stephen L., Awad, Hani A.·2017·Annals of Biomedical Engineering

Abstract

Additive manufacturing, also known as 3D printing, has emerged over the past 3 decades as a disruptive technology for rapid prototyping and manufacturing. Vat polymerization, powder bed fusion, material extrusion, and binder jetting are distinct technologies of additive manufacturing, which have been used in a wide variety of fields, including biomedical research and tissue engineering. The ability to print biocompatible, patient-specific geometries with controlled macro- and micro-pores, and to incorporate cells, drugs and proteins has made 3D-printing ideal for orthopaedic applications, such as bone grafting. Herein, we performed a systematic review examining the fabrication of calcium phosphate (CaP) ceramics by 3D printing, their biocompatibility in vitro, and their bone regenerative potential in vivo, as well as their use in localized delivery of bioactive molecules or cells. Understanding the advantages and limitations of the different 3D printing approaches, CaP materials, and bioactive additives through critical evaluation of in vitro and in vivo evidence of efficacy is essential for developing new classes of bone graft substitutes that can perform as well as autografts and allografts or even surpass the performance of these clinical standards.

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Crossref · 10.1007/s10439-016-1678-3

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Metadata

Authors
Trombetta, R., Inzana, J. A., Schwarz, E. M., Kates, S. L., & Awad, H. A.
Venue
Annals of Biomedical Engineering
Published
2016-06-20
Volume
45
Issue
1
Pages
23-44
ISSN
  • 0090-6964 (ISSN-L)
  • 1573-9686
OpenAlex
W2467652405
Cited by
377
References
89
FWCI
15.81
Type
journal article
Language
en
Open access
green

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CoChat. (2026). Citation check: 3D Printing of Calcium Phosphate Ceramics for Bone Tissue Engineering and Drug Delivery. https://app.cochat.ai/papers/10.1007/s10439-016-1678-3
The paper
Trombetta, R., Inzana, J. A., Schwarz, E. M., Kates, S. L., & Awad, H. A. (2017). 3D Printing of Calcium Phosphate Ceramics for Bone Tissue Engineering and Drug Delivery. Annals of Biomedical Engineering. https://doi.org/10.1007/s10439-016-1678-3

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.