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Behavioral Interventions Targeting Alcohol Use Among People Living with HIV/AIDS: A Systematic Review and Meta-Analysis
Open accessAbstract
Alcohol use is often reported among people living with HIV/AIDS (PLWHA) and is associated with increased sexual risk and poor medication adherence. This meta-analysis evaluated the efficacy of behavioral interventions addressing alcohol use among PLWHA. Twenty-one studies (N = 8461 PLWHA) that evaluated an individual-level intervention addressing alcohol use alone or as part of a more comprehensive alcohol/HIV intervention, included a control condition, and were available through December 2016 were included. Independent raters coded study, sample, and intervention content. Weighted mean effect sizes, using random-effects models, were calculated. Results indicate that interventions reduced alcohol consumption, increased condom use, and improved medication adherence relative to controls (d +s = 0.10-0.24). Plasma viral load was also reduced in intervention versus control participants (d + = 0.14, 95% CI = 0.02, 0.26; k = 7). These findings show that behavioral interventions addressing alcohol use can successfully reduce alcohol consumption and also improve HIV-related outcomes among PLWHA.
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“Randomized clinical trials (RCTs) of alcohol interventions for PWH have had mixed success.”
From A Randomized Feasibility/Acceptability Trial of Acceptance and Commitment Therapy for People with HIV Who Drink at Unhealthy Levels. (2026) · cites this paper as [12]
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An Intervention for Adolescents whose Parents are Living with AIDS
Rotheram‐Borus, M. J., Murphy, D. A., Miller, S., & Draimin, B. (1997) · Clinical Child Psychology and Psychiatry · doi:10.1177/1359104597022003 · Cited by 42
Transtheoretical model and condom use in HIV-positive youths.
Naar-King, S., Wright, K., Parsons, J. T., Frey, M., Templin, T., & Ondersma, S. (2006) · Health Psychology · doi:10.1037/0278-6133.25.5.648 · Cited by 42
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Johnson, B. T., Michie, S., & Snyder, L. B. (2014) · JAIDS Journal of Acquired Immune Deficiency Syndromes · doi:10.1097/qai.0000000000000235 · Cited by 40 · cited 1×
“Although somewhat counter-intuitive, this finding is consistent with the broader literature showing that brief interventions can be more effective than interventions of longer durations in some contexts [61].”
ResultSelf-citationInterventions for families affected by HIV
Rotheram‐Borus, M. J., Swendeman, D. T., Lee, S., Li, L., Amani, B., & Nartey, M. (2011) · Translational Behavioral Medicine · doi:10.1007/s13142-011-0043-1 · Cited by 40
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Motivational Interviewing Targeting Risk Behaviors for Youth Living with HIV in Thailand
Rongkavilit, C., Naar‐King, S., Wang, B., Panthong, A., Bunupuradah, T., Parsons, J. T., Phonphithak, S., Koken, J. A., Saengcharnchai, P., & Phanuphak, P. (2013) · AIDS and Behavior · doi:10.1007/s10461-013-0407-2 · Cited by 36 · cited 1×
“05) a Two outliers were detected for the quantity of alcohol consumed [44, 46] and a single outlier was detected for self-reports of medication adherence [44].”
BackgroundMotivational Interviewing Targeting Risky Sex in HIV-Positive Young Thai Men Who Have Sex with Men
Rongkavilit, C., Wang, B., Naar‐King, S., Bunupuradah, T., Parsons, J. T., Panthong, A., Koken, J. A., Saengcharnchai, P., & Phanuphak, P. (2014) · Archives of Sexual Behavior · doi:10.1007/s10508-014-0274-6 · Cited by 36
Kidder, D. P., Bachanas, P. J., Medley, A. M., Pals, S. L., Nuwagaba‐Biribonwoha, H., Ackers, M., Howard, A. A., DeLuca, N., Mbatia, R., Sheriff, M., et al. (2013) · PLoS ONE · doi:10.1371/journal.pone.0057215 · Cited by 36
Interventions targeting HIV-infected risky drinkers: drops in the bottle.
Samet, J. H., & Walley, A. Y. (2010) · Europe PMC (PubMed Central) · Cited by 35
Transtheoretical Model and substance use in HIV-positive youth
Naar‐King, S., Wright, K., Parsons, J. T., Frey, M., Templin, T., & Ondersma, S. J. (2006) · AIDS Care · doi:10.1080/09540120500467075 · Cited by 35
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Senyonyi, R. M., Underwood, L. A., Suárez, E. C., Musisi, S., & Grande, T. L. (2012) · Health · doi:10.4236/health.2012.412195 · Cited by 31
The NIMH Healthy Living Project Team, Carrico, A. W., Chesney, M. A., Johnson, M. O., Morin, S. F., Neilands, T. B., Remien, R. H., Rotheram‐Borus, M. J., & Wong, F. L. (2008) · AIDS and Behavior · doi:10.1007/s10461-008-9429-6 · Cited by 30
Self-citationIntervention Outcomes Among HIV-Affected Families Over 18 Months
Rotheram‐Borus, M. J., Rice, E. R. W., Comulada, W. S., Best, K. M., Elia, C., Peters, K. W., Li, L., Green, S. K. S., & Valladares, E. S. (2011) · AIDS and Behavior · doi:10.1007/s10461-011-0075-z · Cited by 30
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Meta-Analysis of Research in Social and Personality Psychology
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“, t tests) were used when means and standard deviations were not provided [27, 28].”
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Predictors of Condom Use in a Multisite Study of High-Risk Youth Living with HIV
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Nondisclosure of HIV Infection to Sex Partners and Alcohol’s Role: A Russian Experience
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Association of Violence Victimization with Inconsistent Condom Use in HIV-Infected Persons
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Preventing AIDS: Community-Science Collaborations
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Drinking Motives Among HIV Primary Care Patients
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Depressive Symptoms and Antiretroviral Therapy (ART) Initiation Among HIV-Infected Russian Drinkers
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The influence of depressive symptoms on alcohol use among HIV-infected Russian drinkers
Palfai, T. P., Cheng, D. M., Coleman, S. M., Bridden, C. L., Krupitsky, E. M., & Samet, J. H. (2013) · Drug and Alcohol Dependence · doi:10.1016/j.drugalcdep.2013.09.014 · Cited by 15
Risk factors for recent nonfatal overdose among HIV-infected Russians who inject drugs
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Sexually transmitted infections among HIV-infected heavy drinkers in St Petersburg, Russia
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Savage, C. L., & Sanchez, M. A. (2016) · Journal of Addictions Nursing · doi:10.1097/jan.0000000000000137 · Cited by 12 · cited 1×
“screening and brief interventions among clinic patients can reduce alcohol consumption and avert adverse health consequences associated with alcohol use among PLWHA as well as the broader population in primary care [59, 60]; and (b) Interventions delivered over longer durations were less effective in increasing condom…”
BackgroundComparisons of HIV-affected and non-HIV-affected families over time
Rotheram‐Borus, M. J., Rice, E. R. W., Comulada, W. S., Best, K. M., & Li, L. (2012) · Vulnerable Children and Youth Studies · doi:10.1080/17450128.2012.713532 · Cited by 11
Reasons for Limiting Drinking in an HIV Primary Care Sample
Elliott, J. C., Aharonovich, E., & Hasin, D. S. (2014) · Alcoholism Clinical and Experimental Research · doi:10.1111/acer.12401 · Cited by 11
Longmire-Avital, B., Golub, S. A., & Parsons, J. T. (2010) · Annals of Behavioral Medicine · doi:10.1007/s12160-010-9194-4 · Cited by 11
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Longmire-Avital, B., Holder, C. A., Golub, S. A., & Parsons, J. T. (2012) · The American Journal of Drug and Alcohol Abuse · doi:10.3109/00952990.2011.653425 · Cited by 10
Case management of substance abusers with HIV disease.
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Heroin Use and HIV Disease Progression: Results from a Pilot Study of a Russian Cohort
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A Health Promotion Intervention for Prison Inmates with HIV
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Cited by
Sorted by citations
Velloza, J., Kemp, C. G., Aunon, F. M., Ramaiya, M., Creegan, E., & Simoni, J. M. (2019) · AIDS and Behavior · doi:10.1007/s10461-019-02716-0 · Cited by 147
A Review of Chronic Comorbidities in Adults Living With HIV: State of the Science
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“The effectiveness of abstinence can be enhanced with behavioral interventions that can be delivered by nurses, social workers, and other members of theHIV care team (Addolorato et al., 2016; Scott-Sheldon et al., 2017; Singal et al., 2018).”
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Alcohol Use and the Risk of Communicable Diseases
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“HIV preventionand treatment-related outcomes can be improved by addressing alcohol use through behavioral [90], pharmacological [91], and policy/structural-level interventions [92,93].”
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Metadata
- Authors
- The MASH Research Team, Scott-Sheldon, L. A. J., Carey, K. B., Johnson, B. T., & Carey, M. P.
- Affiliations
- Brown University (US)
- University of Connecticut (US)
- Venue
- AIDS and Behavior
- Published
- 2017-08-22
- Volume
- 21
- Issue
- S2
- Pages
- 126-143
- ISSN
- 1090-7165 (ISSN-L)
- 1573-3254
- PMC
- PMC5660648
- OpenAlex
- W2748537629
- Cited by
- 133
- References
- 174
- Citations by year
- 2026: 5 · 2025: 19 · 2024: 15 · 2023: 22 · 2022: 14 · 2021: 16 · 2020: 20 · 2019: 16 · 2018: 5 · 2017: 1
- FWCI
- 1.52
- Type
- journal article
- Language
- en
- Open access
- green
- europepmc.org
- Locations
- AIDS and Behavior (publishedVersion)
- PubMed (publishedVersion)
- Europe PMC (PubMed Central) (acceptedVersion)
- PubMed Central (acceptedVersion)
- Funders
- National Institute on Alcohol Abuse and Alcoholism
- Topics
- Health Sciences › Medicine › Epidemiology › HIV, Drug Use, Sexual Risk
- Health Sciences › Medicine › Epidemiology › Substance Abuse Treatment and Outcomes
- Health Sciences › Medicine › Infectious Diseases › HIV/AIDS Research and Interventions
- Keywords
- alcohol consumption, people living with HIV, behavioral interventions, alcohol consumption reduction, condom use, medication adherence, viral load, HIV prevention, sexual risk behavior
- MeSH terms
- Acquired Immunodeficiency Syndrome, Alcohol Drinking, Behavior Therapy, Female, Humans, Male, Sexual Behavior, HIV Infections, Treatment Outcome, Viral Load, Alcohol-Related Disorders, Safe Sex, Medication Adherence
About these checks
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