miR-155 in cancer drug resistance and as target for miRNA-based therapeutics

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The Interaction Between Two Worlds: MicroRNAs and Toll-Like Receptors

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FTO Inhibition Enhances the Antitumor Effect of Temozolomide by Targeting MYC-miR-155/23a Cluster-MXI1 Feedback Circuit in Glioma

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MicroRNA and ROS Crosstalk in Cardiac and Pulmonary Diseases

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Targeted delivery of anti-miR-155 by functionalized mesoporous silica nanoparticles for colorectal cancer therapy

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Paclitaxel‑resistant gastric cancer MGC‑803 cells promote epithelial‑to‑mesenchymal transition and chemoresistance in paclitaxel‑sensitive cells via exosomal delivery of miR‑155‑5p

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Role of Exosomal miRNAs and the Tumor Microenvironment in Drug Resistance

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The Impact of Adipose Tissue–Derived miRNAs in Metabolic Syndrome, Obesity, and Cancer

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Targeting miRNAs and Other Non-Coding RNAs as a Therapeutic Approach: An Update

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Dual Suppressive Effect of miR-34a on the FOXM1/eEF2-Kinase Axis Regulates Triple-Negative Breast Cancer Growth and Invasion

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The Role of Exosomal microRNA in Cancer Drug Resistance

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Antisense oligonucleotides for Alzheimer's disease therapy: from the mRNA to miRNA paradigm

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Mechanisms and Strategies to Overcome PD-1/PD-L1 Blockade Resistance in Triple-Negative Breast Cancer

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Drug resistance‐related microRNAs in osteosarcoma: Translating basic evidence into therapeutic strategies

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Tumor-Associated Macrophages in Hepatocellular Carcinoma: Friend or Foe?

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Hepatocellular Carcinoma Cell-Derived Exosomal miR-21-5p Induces Macrophage M2 Polarization by Targeting RhoB

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The Role of miR-155 in Antitumor Immunity

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Decoding the Promise and Challenges of miRNA-Based Cancer Therapies: An Essential Update on miR-21, miR-34, and miR-155

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Non-Coding RNAs as Novel Regulators of Neuroinflammation in Alzheimer’s Disease

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Epigenetic frontiers: miRNAs, long non-coding RNAs and nanomaterials are pioneering to cancer therapy

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Role of Exosomal miRNA in Bladder Cancer: A Promising Liquid Biopsy Biomarker

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Therapeutic Targeting of MicroRNAs in the Tumor Microenvironment

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Enhancer Control of MicroRNA miR-155 Expression in Epstein-Barr Virus-Infected B Cells

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Luteolin inhibits respiratory syncytial virus replication by regulating the MiR-155/SOCS1/STAT1 signaling pathway

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Exosomal microRNA-588 from M2 polarized macrophages contributes to cisplatin resistance of gastric cancer cells

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Advances and challenges in thyroid cancer: The interplay of genetic modulators, targeted therapies, and AI-driven approaches

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Role of miRNA in Melanoma Development and Progression

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Circular RNA Complement Factor H (CFH) Promotes Glioma Progression by Sponging miR-149 and Regulating AKT1

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MiR-155 and other microRNAs downregulate drug metabolizing cytochromes P450 in inflammation

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MicroRNA-155-5p promotes tumor progression and contributes to paclitaxel resistance via TP53INP1 in human breast cancer

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Phytochemicals mediated modulation of microRNAs and long non‐coding RNAs in cancer prevention and therapy

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Nucleolin-Targeting AS1411 Aptamer-Modified Micelle for the Co-Delivery of Doxorubicin and miR-519c to Improve the Therapeutic Efficacy in Hepatocellular Carcinoma Treatment

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Recent advances in the development and clinical application of miRNAs in infectious diseases

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Long noncoding RNA MIR155HG facilitates pancreatic cancer progression through negative regulation of miR‐802

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MicroRNAs in Cancer and Cardiovascular Disease

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Dual miRNA-Triggered DNA Walker Assisted by APE1 for Specific Recognition of Tumor Cells

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miR‐155expression in antitumor immunity: The higher the better?

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Tumor-derived exosomal non-coding RNAs as diagnostic biomarkers in cancer

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Epigenetic regulation by quercetin: a comprehensive review focused on its biological mechanisms

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Myocardial hypertrophy is improved with berberine treatment via long non-coding RNA MIAT-mediated autophagy

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miR-34a Regulates Multidrug Resistance via Positively Modulating OAZ2 Signaling in Colon Cancer Cells

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The role of miR-155-5p in inflammation and mechanical loading during intervertebral disc degeneration

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Identification of RCC Subtype-Specific microRNAs–Meta-Analysis of High-Throughput RCC Tumor microRNA Expression Data

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MicroRNAs in gray and white matter multiple sclerosis lesions: impact on pathophysiology

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miR-142: A Master Regulator in Hematological Malignancies and Therapeutic Opportunities

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Functional Nucleic‐Acid‐Decorated Spherical Nanoparticles: Preparation Strategies and Current Applications in Cancer Therapy

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Mechanism of exosomal miR-155 derived from bone marrow mesenchymal stem cells on stemness maintenance and drug resistance in myeloma cells

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miRNAs in Drug Response Variability: Potential Utility as Biomarkers for Personalized Medicine

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miRNAs and lncRNAs as Predictive Biomarkers of Response to FOLFOX Therapy in Colorectal Cancer

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The Interplay between MicroRNAs and the Components of the Tumor Microenvironment in B-Cell Malignancies

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Inflammation and Inflammasomes: Pros and Cons in Tumorigenesis

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MiR-526b-3p Attenuates Breast Cancer Stem Cell Properties and Chemoresistance by Targeting HIF-2α/Notch Signaling

Liu, J., Li, W., Yang, Y., Qi, Y.-B., Cheng, Y. S., & Wu, J. (2021) · Frontiers in Oncology · doi:10.3389/fonc.2021.696269 · Cited by 29

AntimiR-155 Cyclic Peptide–PNA Conjugate: Synthesis, Cellular Uptake, and Biological Activity

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Circ_0003998 enhances doxorubicin resistance in hepatocellular carcinoma by regulating miR-218-5p/EIF5A2 pathway

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MicroRNAs in extracellular vesicles: A potential role in cancer progression

Parashar, D., Mukherjee, T., Gupta, S. K., Kumar, U., & Das, K. (2024) · Cellular Signalling · doi:10.1016/j.cellsig.2024.111263 · Cited by 27

Extracellular Vesicles Loaded miRNAs as Potential Modulators Shared Between Glioblastoma, and Parkinson’s and Alzheimer’s Diseases

Thomas, L., Florio, T., & Perez-Castro, C. (2020) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2020.590034 · Cited by 28

Triclosan induced zebrafish immunotoxicity by targeting miR-19a and its gene socs3b to activate IL-6/STAT3 signaling pathway

Zhao, C., Xie, R., Qian, Q., Yan, J., Wang, H., & Wang, X. (2022) · The Science of The Total Environment · doi:10.1016/j.scitotenv.2022.152916 · Cited by 27

Radiation therapy for triple-negative breast cancer: emerging role of microRNAs as biomarkers and radiosensitivity modifiers. A systematic review

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Drug Resistance: The Role of Exosomal miRNA in the Microenvironment of Hematopoietic Tumors

Cariello, M., Squilla, A., Piacente, M., Venutolo, G., & Fasano, A. (2022) · Molecules · doi:10.3390/molecules28010116 · Cited by 28

Translational modeling-based evidence for enhanced efficacy of standard-of-care drugs in combination with anti-microRNA-155 in non-small-cell lung cancer

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Circulatory miRNA-155, miRNA-21 target PTEN expression and activity as a factor in breast cancer development

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Pathogenesis of miR-155 on nonmodifiable and modifiable risk factors in Alzheimer’s disease

Liu, J.-J., Long, Y.-F., Xu, P., Guo, H.-D., & Cui, G.-H. (2023) · Alzheimer s Research & Therapy · doi:10.1186/s13195-023-01264-z · Cited by 26

LncRNA-miRNA interaction is involved in colorectal cancer pathogenesis by modulating diverse signaling pathways

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miR-543 regulates the epigenetic landscape of myelofibrosis by targeting TET1 and TET2

Fuentes‐Mattei, E., Bayraktar, R., Manshouri, T., Silva, A. M., Ivan, C., Gulei, D., Fabris, L., do Amaral, N. S., Mur, P., Perez, C., et al. (2020) · JCI Insight · doi:10.1172/jci.insight.121781 · Cited by 25

Shikonin Causes an Apoptotic Effect on Human Kidney Cancer Cells through Ras/MAPK and PI3K/AKT Pathways

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Dapagliflozin prevents kidney podocytes pyroptosis via miR-155-5p/HO-1/NLRP3 axis modulation

Zhang, Z.-W., Ming-qiu, T., Liu, W., Song, Y., Gao, M.-J., Ni, P., Zhang, D., Mo, Q., & Zhao, B. (2024) · International Immunopharmacology · doi:10.1016/j.intimp.2024.111785 · Cited by 28

Chicken gga-miR-1306-5p targets Tollip and plays an important role in host response against Salmonella enteritidis infection

Sun, W., Liu, R., Li, P., Li, Q., Cui, H., Zheng, M., Wen, J., & Zhao, G. (2019) · Journal of Animal Science and Biotechnology/Journal of animal science and biotechnology · doi:10.1186/s40104-019-0365-2 · Cited by 24

MiR ‐155 regulates M2 polarization of hepatitis B virus‐infected tumour‐associated macrophages which in turn regulates the malignant progression of hepatocellular carcinoma

Fei, Y., Wang, Z., Huang, M., Wu, X., Hu, F., Zhu, J., Yu, Y., Shen, H., Wu, Y., Xie, G.-L., et al. (2023) · Journal of Viral Hepatitis · doi:10.1111/jvh.13809 · Cited by 25

Aptamer‐RIBOTAC Strategy Enabling Tumor‐Specific Targeted Degradation of MicroRNA for Precise Cancer Therapy

Fang, Y., Wu, Q., Wang, F., Liu, Y., Zhang, H., Yang, C. J., & Zhu, Z. (2024) · Small Methods · doi:10.1002/smtd.202400349 · Cited by 24

Understanding the role of miRNAs in cervical cancer pathogenesis and therapeutic responses

Chauhan, P. K., Pramodh, S., Hussain, A., Elsori, D. H., Lakhanpal, S., Kumar, R., Alsaweed, M., Iqbal, D., Pandey, P., Othaim, A. A., et al. (2024) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2024.1397945 · Cited by 24

MiRNA-155: A double-edged sword in colorectal cancer progression and drug resistance mechanisms

Hussen, B. M., Sulaiman, S. H. A., Abdullah, S. R., Hidayat, H. J., Khudhur, Z. O., Eslami, S., Samsami, M., & Taheri, M. N. (2025) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2025.140134 · Cited by 23

Engineered Biosensors for Diagnosing Multidrug Resistance in Microbial and Malignant Cells

Jha, N. G., Dkhar, D. S., Singh, S. K., Malode, S. J., Shetti, N. P., & Chandra, P. (2023) · Biosensors · doi:10.3390/bios13020235 · Cited by 24

Functional role of miR‑155 in physiological and pathological processes of liver injury (Review)

Feng, X., Bao, J., Song, C., Xie, L., Tan, X., Li, J., Jia, H., Tian, M., Qi, J., Qin, C., et al. (2021) · Molecular Medicine Reports · doi:10.3892/mmr.2021.12353 · Cited by 22

Tumor-Targeted miRNA Nanomedicine for Overcoming Challenges in Immunity and Therapeutic Resistance

Parayath, N. N., Gandham, S. K., & Amiji, M. M. (2022) · Nanomedicine · doi:10.2217/nnm-2022-0130 · Cited by 23

Single Shot vs. Cocktail: A Comparison of Mono- and Combinative Application of miRNA-Targeted Mesyl Oligonucleotides for Efficient Antitumor Therapy

Gaponova, S., Patutina, O., Васильевна, С. А., Burakova, E. A., Savin, I. A., Markov, A. V., Shmendel, E. V., Maslov, M. A., Stetsenko, D. A., Vlassov, V. V., et al. (2022) · Cancers · doi:10.3390/cancers14184396 · Cited by 21

miR‑155 inhibition represents a potential valuable regulator in mitigating myocardial hypoxia/reoxygenation injury through targeting BAG5 and MAPK/JNK signaling

Xi, J., Li, Q., Li, B., & Li, N. (2020) · Molecular Medicine Reports · doi:10.3892/mmr.2020.10924 · Cited by 22

lncRNA CASC2 Enhances 131I Sensitivity in Papillary Thyroid Cancer by Sponging miR‐155

Tao, L., Tian, P., Yang, L., & Guo, X. (2020) · BioMed Research International · doi:10.1155/2020/7183629 · Cited by 19

MiR-195-5p inhibits proliferation and invasion of nerve cells in Hirschsprung disease by targeting GFRA4

Wang, G., Wang, H., Zhang, L., Guo, F., Wu, X., & Liu, Y. (2021) · Molecular and Cellular Biochemistry · doi:10.1007/s11010-021-04055-y · Cited by 19

PBMC gene expression profiles of female Bangladeshi adults chronically exposed to arsenic-contaminated drinking water

Chen, Q. Y., Shen, S., Sun, H. Y., Wu, F., Kluz, T., Kibriya, M. G., Chen, Y., Ahsan, H., & Costa, M. (2019) · Environmental Pollution · doi:10.1016/j.envpol.2019.113672 · Cited by 19

Upregulation of Akt/Raptor signaling is associated with rapamycin resistance of breast cancer cells

Shchegolev, Y. Y., Sorokin, D. V., Scherbakov, A. M., Shunaev, A., Andreeva, O. E., Mikhaevich, E. I., Gudkova, M. V., Bure, I. V., Berstein, L. M., Nemtsova, M. V., et al. (2020) · Chemico-Biological Interactions · doi:10.1016/j.cbi.2020.109243 · Cited by 18

A Literature Review on the Antiviral Mechanism of Luteolin

Lu, P., Zhang, T., Ren, Y., Rao, H., Lei, J., Zhao, G., Wang, M., Gong, D., & Cao, Z. (2023) · Natural Product Communications · doi:10.1177/1934578x231171521 · Cited by 19

Unraveling Therapeutic Opportunities and the Diagnostic Potential of microRNAs for Human Lung Cancer

Sweef, O., Zaabout, E., Bakheet, A., Halawa, M. R., Gad, I., Akela, M. A., Tousson, E., Abdelghany, A., & Furuta, S. (2023) · Pharmaceutics · doi:10.3390/pharmaceutics15082061 · Cited by 22

Cancer drug resistance related microRNAs: recent advances in detection methods

Hu, X., Song, Z., Yang, Z.-W., Li, J., Liu, J., & Wang, H. (2022) · The Analyst · doi:10.1039/d2an00171c · Cited by 18

Regulation of Oncogenic Targets by Tumor-Suppressive miR-150-3p in Lung Squamous Cell Carcinoma

Mizuno, K., Tanigawa, K., Misono, S., Suetsugu, T., Sanada, H., Uchida, A., Kawano, M., Machida, K., Asai, S., Moriya, S., et al. (2021) · Biomedicines · doi:10.3390/biomedicines9121883 · Cited by 16

MicroRNA-155-5p in pathogenesis of cancer

Zborovskaya, I. B., & Komelkov, A. V. (2017) · Advances in molecular oncology · doi:10.17650/2313-805x-2017-4-3-27-36 · Cited by 4

miR-155 as a novel clinical target for hematological malignancies

Witten, L., & Slack, F. J. (2019) · Carcinogenesis · doi:10.1093/carcin/bgz183 · Cited by 104

The Role of miR-155 in Antitumor Immunity

Kalkusova, K., Táborská, P., Stakheev, D., & Smrž, D. (2022) · Cancers · doi:10.3390/cancers14215414 · Cited by 76

MiR‐145 in cancer therapy resistance and sensitivity: A comprehensive review

Xu, W., Hua, Y.-T., Deng, F., Wang, D., Wu, Y. F., Zhang, W., & Tang, J. (2020) · Cancer Science · doi:10.1111/cas.14517 · Cited by 67

The multiple roles of microRNA-155 in oncogenesis

Higgs, G., & Slack, F. (2013) · Journal of Clinical Bioinformatics · doi:10.1186/2043-9113-3-17 · Cited by 137