miR-155 in cancer drug resistance and as target for miRNA-based therapeutics

MicroRNAs: Target Recognition and Regulatory Functions

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A microRNA expression signature of human solid tumors defines cancer gene targets

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Regulation of microRNA biogenesis

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PD-1 and Its Ligands in Tolerance and Immunity

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Predictive correlates of response to the anti-PD-L1 antibody MPDL3280A in cancer patients

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Frequent deletions and down-regulation of micro- RNA genes miR15 and miR16 at 13q14 in chronic lymphocytic leukemia

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NF-κB-dependent induction of microRNA miR-146, an inhibitor targeted to signaling proteins of innate immune responses

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Identification of tissue-specific microRNAs from mouse

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Unique microRNA molecular profiles in lung cancer diagnosis and prognosis

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MPDL3280A (anti-PD-L1) treatment leads to clinical activity in metastatic bladder cancer

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International Journal of Oncology

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MicroRNA-155 is induced during the macrophage inflammatory response

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Identification of hundreds of conserved and nonconserved human microRNAs

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Requirement of bic/microRNA-155 for Normal Immune Function

Rodriguez, A., Vigorito, E., Clare, S., Warren, M. V., Couttet, P., Soond, D. R., van Dongen, S., Grocock, R. J., Das, P. P., Miska, E. A., et al. (2007) · Science · doi:10.1126/science.1139253 · Cited by 1,833

Accumulation of miR-155 and BIC RNA in human B cell lymphomas

Eis, P. S., Tam, W., Sun, L., Chadburn, A., Li, Z., Gomez, M. F., Lund, E., & Dahlberg, J. E. (2005) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0500613102 · Cited by 1,322

Pre-B cell proliferation and lymphoblastic leukemia/high-grade lymphoma in Eμ-miR155 transgenic mice

Costinean, S., Zanesi, N. A. O., Pekarsky, Y., Tili, E., Volinia, S., Heerema, N. A., & Croce, C. M. (2006) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0602266103 · Cited by 952

Inositol phosphatase SHIP1 is a primary target of miR-155

O'Connell, R. M., Chaudhuri, A. A., Rao, D. S., & Baltimore, D. (2009) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0902636106 · Cited by 826

miR-155 gene: A typical multifunctional microRNA

Faraoni, I., Antonetti, F. R., Cardone, J., & Bonmassar, E. (2009) · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · doi:10.1016/j.bbadis.2009.02.013 · Cited by 815

Foxp3-Dependent MicroRNA155 Confers Competitive Fitness to Regulatory T Cells by Targeting SOCS1 Protein

Lu, L., Thai, T., Calado, D. P., Chaudhry, A., Kubo, M., Tanaka, K., Loeb, G. B., Lee, H., Yoshimura, A., Rajewsky, K., et al. (2009) · Immunity · doi:10.1016/j.immuni.2008.11.010 · Cited by 797

microRNA-155 Regulates the Generation of Immunoglobulin Class-Switched Plasma Cells

Vigorito, E., Perks, K. L., Abreu‐Goodger, C., Bunting, S., Xiang, Z., Kohlhaas, S. L., Das, P. P., Miska, E. A., Rodriguez, A., Bradley, A., et al. (2007) · Immunity · doi:10.1016/j.immuni.2007.10.009 · Cited by 763

MicroRNA-155 Functions as an OncomiR in Breast Cancer by Targeting the Suppressor of Cytokine Signaling 1 Gene

Jiang, S., Zhang, H.-W., Lu, M.-H., He, X.-H., Li, Y., Gu, H., Liu, M.-F., & Wang, E.-D. (2010) · Cancer Research · doi:10.1158/0008-5472.can-09-4250 · Cited by 679

BIC and miR‐155 are highly expressed in Hodgkin, primary mediastinal and diffuse large B cell lymphomas

Kluiver, J. L., Poppema, S., de Jong, D., Blokzijl, T., Harms, G., Jacobs, S. C., Kroesen, B., & van den Berg, A. (2005) · The Journal of Pathology · doi:10.1002/path.1825 · Cited by 675

MicroRNA-155 as a proinflammatory regulator in clinical and experimental arthritis

Kurowska‐Stolarska, M., Alivernini, S., Ballantine, L. E., Asquith, D. L., Millar, N. L., Gilchrist, D. S., Reilly, J. H., Ierna, M. X., Fraser, A. R., Stolarski, B., et al. (2011) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1019536108 · Cited by 639

Transcription factors in myeloid development: balancing differentiation with transformation

Rosenbauer, F., & Tenen, D. G. (2007) · Nature Reviews Immunology · doi:10.1038/nri2024 · Cited by 606 · cited 1×

Tumor protein 53-induced nuclear protein 1 expression is repressed by miR-155, and its restoration inhibits pancreatic tumor development

Gironella, M., Seux, M., Xie, M.-J., Cano, C. E., Tomasini, R., Gommeaux, J., Garcia, S., Nowak, J., Yeung, M. L., Jeang, K., et al. (2007) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0703942104 · Cited by 548

Distinctive microRNA signature of acute myeloid leukemia bearing cytoplasmic mutated nucleophosmin

Garzon, R., Garofalo, M., Martelli, M. P., Briesewitz, R., Wang, L., Fernandez-Cymering, C., Volinia, S., Liu, C., Schnittger, S., Haferlach, T., et al. (2008) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0800135105 · Cited by 507

Quantitative technologies establish a novel microRNA profile of chronic lymphocytic leukemia

Fulci, V., Chiaretti, S., Goldoni, M., Azzalin, G., Carucci, N., Tavolaro, S., Castellano, L., Magrelli, A., Citarella, F., Messina, M., et al. (2007) · Blood · doi:10.1182/blood-2006-12-062398 · Cited by 506

Nanoparticle-based therapy in an in vivo microRNA-155 (miR-155)-dependent mouse model of lymphoma

Babar, I., Cheng, C. J., Booth, C. J., Liang, X., Weidhaas, J. B., Saltzman, W. M., & Slack, F. J. (2012) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1201516109 · Cited by 506

CD34+ hematopoietic stem-progenitor cell microRNA expression and function: A circuit diagram of differentiation control

Georgantas, R. W., Hildreth, R. L., Morisot, S., Alder, J. K., Liu, C., Heimfeld, S., Calin, G. A., Croce, C. M., & Civin, C. I. (2007) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0610983104 · Cited by 501

Upregulation of miRNA-155 promotes tumour angiogenesis by targeting VHL and is associated with poor prognosis and triple-negative breast cancer

Kong, W. W., He, L., Richards, E. J., Challa, S., Cx, X., Permuth‐Wey, J., Lancaster, J., Coppola, D., Sellers, T. A., Djeu, J. Y., et al. (2013) · Oncogene · doi:10.1038/onc.2012.636 · Cited by 428

Microrna expression distinguishes between germinal center B cell‐like and activated B cell‐like subtypes of diffuse large B cell lymphoma

Lawrie, C. H., Soneji, S., Marafioti, T., Cooper, C. D. O., Palazzo, S., Paterson, J. C., Cattan, H., Enver, T., Mager, R., Boultwood, J., et al. (2007) · International Journal of Cancer · doi:10.1002/ijc.22800 · Cited by 415

Cell-to-cell communication: microRNAs as hormones.

Bayraktar, R., Van Roosbroeck, K., & Calin, G. A. (2017) · Molecular Oncology · doi:10.1002/1878-0261.12144 · Cited by 361

miR-155 : On the Crosstalk Between Inflammation and Cancer

Tili, E., Croce, C. M., & Michaille, J. (2009) · International Reviews of Immunology · doi:10.1080/08830180903093796 · Cited by 346

Src homology 2 domain–containing inositol-5-phosphatase and CCAAT enhancer-binding protein β are targeted by miR-155 in B cells of Eμ-MiR-155 transgenic mice

Costinean, S., Sandhu, S. K., Pedersen, I. M., Tili, E., Trotta, R., Perrotti, D., Ciarlariello, D., Neviani, P., Harb, J. G., Kauffman, L. R., et al. (2009) · Blood · doi:10.1182/blood-2009-05-220814 · Cited by 292

MicroRNA-155 Controls Exosome Synthesis and Promotes Gemcitabine Resistance in Pancreatic Ductal Adenocarcinoma

Mikamori, M., Yamada, D., Eguchi, H., Hasegawa, S., Kishimoto, T., Tomimaru, Y., Asaoka, T., Noda, T., Wada, H., Kawamoto, K., et al. (2017) · Scientific Reports · doi:10.1038/srep42339 · Cited by 272

Identification and characterization of human BIC, a gene on chromosome 21 that encodes a noncoding RNA

Tam, W. (2001) · Gene · doi:10.1016/s0378-1119(01)00612-6 · Cited by 268

Exosomes confer chemoresistance to pancreatic cancer cells by promoting ROS detoxification and miR-155-mediated suppression of key gemcitabine-metabolising enzyme, DCK

Patel, G. K., Khan, M. A., Bhardwaj, A., Srivastava, S. K., Zubair, H., Patton, M. C., Singh, S., Khushman, M. M., & Singh, A. P. (2017) · British Journal of Cancer · doi:10.1038/bjc.2017.18 · Cited by 268

MicroRNAs and chromosomal abnormalities in cancer cells

Calin, G. A., & Croce, C. M. (2006) · Oncogene · doi:10.1038/sj.onc.1209910 · Cited by 262

Epstein–Barr virus latent membrane protein 1 trans-activates miR-155 transcription through the NF-κB pathway

Gatto, G., Rossi, A., Rossi, D. P., Kroening, S., Bonatti, S., & Mallardo, M. (2008) · Nucleic Acids Research · doi:10.1093/nar/gkn666 · Cited by 254

Mutator activity induced by microRNA-155 ( miR-155 ) links inflammation and cancer

Tili, E., Michaille, J., Wernicke, D., Alder, H., Costinean, S., Volinia, S., & Croce, C. M. (2011) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1101795108 · Cited by 233

Tumor suppressor BRCA1 epigenetically controls oncogenic microRNA-155

Chang, S., Wang, R., Akagi, K., Kim, K.-A., Martin, B. K., Cavallone, L., Haines, D. C., Basik, M., Mai, P., Poggi, E. A., et al. (2011) · Nature Medicine · doi:10.1038/nm.2459 · Cited by 232

Prognostic value of miR-155 in individuals with monoclonal B-cell lymphocytosis and patients with B chronic lymphocytic leukemia

Ferrajoli, A., Shanafelt, T. D., Ivan, C., Shimizu, M., Rabe, K. G., Nouraee, N., Ikuo, M., Ghosh, A. K., Lerner, S. A., Rassenti, L. Z., et al. (2013) · Blood · doi:10.1182/blood-2013-01-478222 · Cited by 218

Protective role of miR-155 in breast cancer through RAD51 targeting impairs homologous recombination after irradiation

Gasparini, P., Lovat, F., Fassan, M., Casadei, L., Cascione, L., Jacob, N. K., Carasi, S., Palmieri, D., Costinean, S., Shapiro, C. L., et al. (2014) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1402604111 · Cited by 216

Onco‐miR‐155 targets SHIP1 to promote TNFα‐dependent growth of B cell lymphomas

Pedersen, I. M., Otero, D. C., Kao, E., Miletic, A. V., Hother, C., Ralfkiaer, E. M., Rickert, R. C., Grønbæk, K., & David, M. (2009) · EMBO Molecular Medicine · doi:10.1002/emmm.200900028 · Cited by 209

MicroRNA-155 influences B-cell receptor signaling and associates with aggressive disease in chronic lymphocytic leukemia

Cui, B., Chen, L., Zhang, S., Mráz, M., Fecteau, J.-F., Yu, J., Ghia, E. M., Zhang, L., Bao, L., Rassenti, L. Z., et al. (2014) · Blood · doi:10.1182/blood-2014-03-559690 · Cited by 208

Epstein-Barr Virus-Induced miR-155 Attenuates NF-κB Signaling and Stabilizes Latent Virus Persistence

Lu, F., Weidmer, A., Liu, C.-G., Volinia, S., Croce, C. M., & Lieberman, P. M. (2008) · Journal of Virology · doi:10.1128/jvi.00752-08 · Cited by 190

T cell activation induces a noncoding RNA transcript sensitive to inhibition by immunosuppressant drugs and encoded by the proto-oncogene, BIC

Haasch, D. L., Chen, Y., Reilly, R. M., Chiou, X. G., Koterski, S., Smith, M. L., Kroeger, P., McWeeny, K., Halbert, D. N., Mollison, K. W., et al. (2002) · Cellular Immunology · doi:10.1016/s0008-8749(02)00506-3 · Cited by 189

MiR-21 and MiR-155 promote non-small cell lung cancer progression by downregulating SOCS1, SOCS6, and PTEN

Xue, X., Liu, Y., Wang, Y., Meng, M., Wang, K., Zang, X., Zhao, S., Sun, X., Cui, L., Pan, L., et al. (2016) · Oncotarget · doi:10.18632/oncotarget.13022 · Cited by 187

Combining Anti-Mir-155 with Chemotherapy for the Treatment of Lung Cancers

Roosbroeck, K. V., Fanini, F., Setoyama, T., Ivan, C., Rodriguez‐Aguayo, C., Fuentes‐Mattei, E., Xiao, L., Vannini, I., Redis, R. S., D’Abundo, L., et al. (2016) · Clinical Cancer Research · doi:10.1158/1078-0432.ccr-16-1025 · Cited by 180

Expression patterns of microRNAs 155 and 451 during normal human erythropoiesis.

Masaki, S., Ohtsuka, R., Abe, Y., Muta, K., & Umemura, T. (2007) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2007.10.077 · Cited by 178

Mutant p53 drives invasion in breast tumors through up-regulation of miR-155

Neilsen, P. M., Noll, J. E., Mattiske, S., Bracken, C. P., Gregory, P. A., Schulz, R. B., Lim, S. P., Kumar, R., Suetani, R. J., Goodall, G. J., et al. (2012) · Oncogene · doi:10.1038/onc.2012.305 · Cited by 171

Micro RNA ‐155‐5p promotes hepatocellular carcinoma progression by suppressing PTEN through the PI 3K/Akt pathway

Fu, X., Wen, H., Li, J., Yang, Y., Wang, W., Liang, X., Nan, K., Yao, Y., & Tian, T. (2017) · Cancer Science · doi:10.1111/cas.13177 · Cited by 164

MiR-155-mediated loss of C/EBPβ shifts the TGF-β response from growth inhibition to epithelial-mesenchymal transition, invasion and metastasis in breast cancer

Johansson, J., Berg, T., Kurzejamska, E., Pang, M.-F., Tabor, V., Jansson, M., Roswall, P., Pietras, K., Sund, M., Religa, P., et al. (2013) · Oncogene · doi:10.1038/onc.2013.322 · Cited by 154

MYB transcriptionally regulates the miR-155 host gene in chronic lymphocytic leukemia

Vargová, K., Čuřík, N., Burda, P., Bašová, P., Kulvait, V., Pospíšil, V., Savvulidi, F. G., Kokavec, J., Nečas, E., Berková, A., et al. (2011) · Blood · doi:10.1182/blood-2010-05-285064 · Cited by 144

Regulation of pri-microRNA BIC transcription and processing in Burkitt lymphoma

Kluiver, J. L., van den Berg, A., de Jong, D., Blokzijl, T., Harms, G., Bouwman, E., Jacobs, S. C., Poppema, S., & Kroesen, B. J. (2006) · Oncogene · doi:10.1038/sj.onc.1210147 · Cited by 139

MicroRNA 603 acts as a tumor suppressor and inhibits triple-negative breast cancer tumorigenesis by targeting elongation factor 2 kinase

Bayraktar, R., Pichler, M., Kanlikilicer, P., Ivan, C., Bayraktar, E., Kahraman, N., Aslan, B., Oğuztüzün, S., Ulaşlı, M., Arslan, A., et al. (2016) · Oncotarget · doi:10.18632/oncotarget.14264 · Cited by 138

MicroRNA-155 induction via TNF-α and IFN-γ suppresses expression of programmed death ligand-1 (PD-L1) in human primary cells

Yee, D., Shah, K., Coles, M. C., Sharp, T. V., & Lagos, D. (2017) · Journal of Biological Chemistry · doi:10.1074/jbc.m117.809053 · Cited by 137

miRNAs and long noncoding RNAs as biomarkers in human diseases

Roosbroeck, K. V., Pollet, J. B. K., & Călin, G. A. (2013) · Expert Review of Molecular Diagnostics · doi:10.1586/erm.12.134 · Cited by 136

Ubiquitous Release of Exosomal Tumor Suppressor miR-6126 from Ovarian Cancer Cells

Kanlikilicer, P., Rashed, M. H., Bayraktar, R., Mitra, R., Ivan, C., Aslan, B., Zhang, X., Filant, J., da Silva, A. M., Rodriguez‐Aguayo, C., et al. (2016) · Cancer Research · doi:10.1158/0008-5472.can-16-0714 · Cited by 136

NF-κB/STAT5/miR-155 network targets PU.1 in FLT3-ITD-driven acute myeloid leukemia

Gerloff, D., Grundler, R., Wurm, A. A., Bräuer-Hartmann, D., Katzerke, C., Hartmann, J.-U., Madan, V, Müller-Tidow, C., Duyster, J., Tenen, D. G., et al. (2015) · Leukemia · doi:10.1038/leu.2014.231 · Cited by 135

microRNAs as cancer therapeutics: A step closer to clinical application

Ivković, T. C., Voss, G., Cornellà, H., & Ceder, Y. (2017) · Cancer Letters · doi:10.1016/j.canlet.2017.04.007 · Cited by 134

Quantitative Proteomics Reveals that miR-155 Regulates the PI3K-AKT Pathway in Diffuse Large B-Cell Lymphoma

Huang, X., Shen, Y., Liu, M., Bi, C., Jiang, C., Iqbal, J., McKeithan, T. W., Chan, W. C., Ding, S., & Fu, K. (2012) · American Journal Of Pathology · doi:10.1016/j.ajpath.2012.03.013 · Cited by 131

miR-155 targets histone deacetylase 4 (HDAC4) and impairs transcriptional activity of B-cell lymphoma 6 (BCL6) in the Eµ-miR-155 transgenic mouse model

Sandhu, S. K., Volinia, S., Costinean, S., Galasso, M., Neinast, R., Santhanam, R., Parthun, M. R., Perrotti, D., Marcucci, G., Garzon, R., et al. (2012) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1213764109 · Cited by 130

miR-155 Drives Telomere Fragility in Human Breast Cancer by Targeting TRF1

Dinami, R., Ercolani, C., Petti, E., Piazza, S., Ciani, Y., Sestito, R., Sacconi, A., Biagioni, F., le Sage, C., Agami, R., et al. (2014) · Cancer Research · doi:10.1158/0008-5472.can-13-2038 · Cited by 129

Inhibition of hypoxia-induced miR-155 radiosensitizes hypoxic lung cancer cells

Babar, I., Czochor, J. R., Steinmetz, A., Weidhaas, J. B., Glazer, P. M., & Slack, F. J. (2011) · Cancer Biology & Therapy · doi:10.4161/cbt.12.10.17681 · Cited by 128

Aberrant expression of microRNA 155 may accelerate cell proliferation by targeting sex‐determining region Y box 6 in hepatocellular carcinoma

Xie, Q., Chen, X., Lu, F., Zhang, T., Hao, M., Wang, Y., Zhao, J., McCrae, M. A., & Zhuang, H. (2011) · Cancer · doi:10.1002/cncr.26566 · Cited by 118

Oncogenic MicroRNA-155 Down-regulates Tumor Suppressor CDC73 and Promotes Oral Squamous Cell Carcinoma Cell Proliferation

Rather, M. I., Nagashri, M. N., Swamy, S. S., Gopinath, K. S., & Kumar, A. (2012) · Journal of Biological Chemistry · doi:10.1074/jbc.m112.425736 · Cited by 118

MiR-155 inhibits the sensitivity of lung cancer cells to cisplatin via negative regulation of Apaf-1 expression

Zang, Y.-S., Zhong, Y.-F., Fang, Z., Li, B., & An, J. (2012) · Cancer Gene Therapy · doi:10.1038/cgt.2012.60 · Cited by 107

MicroRNA-155 as an inducer of apoptosis and cell differentiation in Acute Myeloid Leukaemia

Palma, C. A., Sheikha, D. A., Lim, T. K., Bryant, A. J., Vu, T. T., Jayaswal, V., & Ma, D. D. F. (2014) · Molecular Cancer · doi:10.1186/1476-4598-13-79 · Cited by 107

Cisplatin Sensitivity Mediated by WEE1 and CHK1 Is Mediated by miR-155 and the miR-15 Family

Pouliot, L. M., Chen, Y., Bai, J., Guha, R., Martin, S. E., Gottesman, M. M., & Hall, M. D. (2012) · Cancer Research · doi:10.1158/0008-5472.can-12-1400 · Cited by 101

miR-155 is up-regulated in primary and secondary glioblastoma and promotes tumour growth by inhibiting GABA receptors

Marsigliante, S. (2012) · International Journal of Oncology · doi:10.3892/ijo.2012.1420 · Cited by 100

Host miR155 Promotes Tumor Growth through a Myeloid-Derived Suppressor Cell–Dependent Mechanism

Chen, S., Wang, L., Fan, J., Ye, C., Dominguez, D., Zhang, Y., Curiel, T. J., Fang, D., Kuzel, T. M., & Zhang, B. (2014) · Cancer Research · doi:10.1158/0008-5472.can-14-2331 · Cited by 100

MiRNA-155 mediates TAM resistance by modulating SOCS6-STAT3 signalling pathway in breast cancer.

Shen, R., Wang, Y., Wang, C., Yin, M., Liu, H., Chen, J., Han, J., & Wang, W.-B. (2015) · Europe PMC (PubMed Central) · Cited by 97

miR-155 promotes macroscopic tumor formation yet inhibits tumor dissemination from mammary fat pads to the lung by preventing EMT

Xiang, X., Zhuang, X., Ju, S., Zhang, S., Jiang, H., Mu, J., Zhang, L., Miller, D. M., Grizzle, W. E., & Zhang, H. (2011) · Oncogene · doi:10.1038/onc.2011.54 · Cited by 95

MicroRNA-155 as a proinflammatory regulator via SHIP-1 down-regulation in acute gouty arthritis

Jin, H. M., Kim, T., Choi, J., Kim, M., Cho, Y., Nam, K. I., Kee, S., Moon, J. B., Choi, S., Park, D.-J., et al. (2014) · Arthritis Research & Therapy · doi:10.1186/ar4531 · Cited by 90

Lactosylated gramicidin-based lipid nanoparticles (Lac-GLN) for targeted delivery of anti-miR-155 to hepatocellular carcinoma

Zhang, M., Zhou, X., Wang, B., Yung, B. C., Lee, L. J., Ghoshal, K., & Lee, R. J. (2013) · Journal of Controlled Release · doi:10.1016/j.jconrel.2013.03.020 · Cited by 87

Pharmacological targeting of miR-155 via the NEDD8-activating enzyme inhibitor MLN4924 (Pevonedistat) in FLT3-ITD acute myeloid leukemia

Khalife, J., Radomska, H. S., Santhanam, R., Huang, X., Neviani, P., Saultz, J. N., Wang, H., Wu, Y.-Z., Alachkar, H., Anghelina, M. I., et al. (2015) · Leukemia · doi:10.1038/leu.2015.106 · Cited by 83

NF-κB–driven suppression of FOXO3a contributes to EGFR mutation-independent gefitinib resistance

Chiu, C., Chang, Y.-W., Kuo, K.-T., Shen, Y.-S., Liu, C., Yu, Y., Cheng, C.-C., Lee, K., Chen, F., Hsu, M.-K., et al. (2016) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1522612113 · Cited by 82

Integrated miRNA and mRNA expression profiling of mouse mammary tumor models identifies miRNA signatures associated with mammary tumor lineage

Zhu, M., Yi, M., Kim, C. H., Deng, C., Li, Y., Medina, D., Stephens, R. M., & Green, J. E. (2011) · Genome biology · doi:10.1186/gb-2011-12-8-r77 · Cited by 75

miR-155 regulates HGAL expression and increases lymphoma cell motility

Dagan, L. N., Jiang, X., Bhatt, S., Cubedo, E., Rajewsky, K., & Lossos, I. S. (2011) · Blood · doi:10.1182/blood-2011-08-370536 · Cited by 72

Increased miR-155-5p and reduced miR-148a-3p contribute to the suppression of osteosarcoma cell death

Bhattacharya, S., Chalk, A. M., Ng, A. J. M., Martin, T. J., Zannettino, A. C. W., Purton, L. E., Lü, J., Baker, E. K., & Walkley, C. R. (2016) · Oncogene · doi:10.1038/onc.2016.68 · Cited by 72

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miR‐155 Regulates Glioma Cells Invasion and Chemosensitivity by p38 Isforms In Vitro

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Involvement of miR-155/FOXO3a and miR-222/PTEN in acquired radioresistance of colorectal cancer cell line

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miR-155 promotes FLT3-ITD–induced myeloproliferative disease through inhibition of the interferon response

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Morin promotes prostate cancer cells chemosensitivity to paclitaxel through miR-155/GATA3 axis

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Functionally distinct roles for different miR-155 expression levels through contrasting effects on gene expression, in acute myeloid leukaemia

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Adrenaline promotes cell proliferation and increases chemoresistance in colon cancer HT29 cells through induction of miR-155

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miR-125b and miR-155 Contribute to BCL2 Repression and Proliferation in Response to CD40 Ligand (CD154) in Human Leukemic B-cells

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Exosomal miR-940 maintains SRC-mediated oncogenic activity in cancer cells: a possible role for exosomal disposal of tumor suppressor miRNAs

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Inhibition of miR-155, a therapeutic target for breast cancer, prevented in cancer stem cell formation

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MiR‐155 targets TP53INP1 to regulate liver cancer stem cell acquisition and self‐renewal

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MicroRNA-155 promotes bladder cancer growth by repressing the tumor suppressor DMTF1

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miR-155 mediates arsenic trioxide resistance by activating Nrf2 and suppressing apoptosis in lung cancer cells

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Up-regulated miR155 Reverses the Epithelial-mesenchymal Transition Induced by EGF and Increases Chemo-sensitivity to Cisplatin in Human Caski Cervical Cancer Cells

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MiR-155-5p positively regulates CCL17-induced colon cancer cell migration by targeting RhoA

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Epstein–Barr virus latent membrane protein-1 protects B-cell lymphoma from rituximab-induced apoptosis through miR-155-mediated Akt activation and up-regulation of Mcl-1

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miR-155 mediates drug resistance in osteosarcoma cells via inducing autophagy

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Oncogenic role of miR ‐155 in anaplastic large cell lymphoma lacking the t(2;5) translocation

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Effect of miR-155 knockdown on the reversal of doxorubicin resistance in human lung cancer A549/dox cells

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Preliminary Results of a Phase 1 Trial Evaluating MRG-106, a Synthetic microRNA Antagonist (LNA antimiR) of microRNA-155, in Patients with CTCL

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MiRNA-155 promotes proliferation by targeting caudal-type homeobox 1 (CDX1) in glioma cells

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MiR‐155 inhibits proliferation and invasion by directly targeting PDCD 4 in non‐small cell lung cancer

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Angiotensin II type I receptor and miR-155 in endometrial cancers: Synergistic antiproliferative effects of anti-miR-155 and losartan on endometrial cancer cells

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Transforming Growth Factor β1/Smad4 Signaling Affects Osteoclast Differentiation via Regulation of miR-155 Expression

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miR-155 regulates the proliferation and cell cycle of colorectal carcinoma cells by targeting E2F2

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HOXA9 regulates miR-155 in hematopoietic cells

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FOXO Transcription Factors Enforce Cell Cycle Checkpoints and Promote Survival of Hematopoietic Cells after DNA Damage

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Inhibition of microRNA-155 sensitizes lung cancer cells to irradiation via suppression of HK2-modulated glucose metabolism

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MicroRNAs in chronic lymphocytic leukemia: miRacle or miRage for prognosis and targeted therapies?

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Sponges against miR-19 and miR-155 reactivate the p53-Socs1 axis in hematopoietic cancers

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Epstein-Barr virus-encoded LMP1 increases miR-155 expression, which promotes radioresistance of nasopharyngeal carcinoma via suppressing UBQLN1.

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Anti‐miR‐155 oligonucleotide enhances chemosensitivity of U251 cell to taxol by inducing apoptosis

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Matrix Gla protein repression by miR‐155 promotes oncogenic signals in breast cancer MCF‐7 cells

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Chronic treatment of non-small-cell lung cancer cells with gefitinib leads to an epigenetic loss of epithelial properties associated with reductions in microRNA-155 and -200c

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miR-155 inhibitor reduces the proliferation and migration in osteosarcoma MG-63 cells

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miR-155 regulative network in FLT3 mutated acute myeloid leukemia

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Seed targeting with tiny anti-miR-155 inhibits malignant progression of multiple myeloma cells

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Improving vascular maturation using noncoding RNAs increases antitumor effect of chemotherapy

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Improving vascular maturation using noncoding RNAs increases antitumor effect of chemotherapy

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In Vitro Induction of Human Regulatory T-Cells (iTregs) Using Conditions of Low Tryptophan Plus Kynurenines

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The Potential for microRNA Therapeutics and Clinical Research

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MicroRNA: trends in clinical trials of cancer diagnosis and therapy strategies

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RNA-Based Therapeutics: From Antisense Oligonucleotides to miRNAs

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MicroRNA-155-5p in pathogenesis of cancer

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