Mindfulness-based cognitive therapy for perinatal women with depression or bipolar spectrum disorder
Open accessAbstract
The perinatal period is a high-risk time for mood deterioration among women vulnerable to depression. This study examined feasibility, acceptability, and improvement associated with mindfulness-based cognitive therapy (MBCT) in perinatal women with major depressive disorder (MDD) or bipolar spectrum disorder (BSD). Following a diagnostic evaluation, 39 perinatal women with a lifetime history of MDD (n = 27) or BSD (n = 12) enrolled in an 8-week program of MBCT classes (2 h each) that incorporated meditation, yoga, and mood regulation strategies. Participants were pregnant (n = 12), planning pregnancy (n = 11), or up to 1-year postpartum (n = 16). Participants were self-referred and most had subthreshold mood symptoms. Assessments of depression, (hypo)mania, and anxiety were obtained by interview and self-report at baseline, post-treatment and at 1- and 6-month post-treatment. Women with a history of MDD were more likely to complete the classes than women with BSD. Of 32 women who completed the classes, 7 (21.9 %) had a major depressive episode during the 6-month post-treatment follow-up. On average, participants with MDD reported improvements in depression from pre- to post-treatment. Mood improvement was not observed in the BSD group. In the full sample, improvements in depression symptoms across time points were associated with increasing mindful tendency scores. This study was limited by its uncontrolled design, heterogeneous sample, and questionnaire-based assessment of mindfulness skills. MBCT may be an important component of care for perinatal women with histories of major depression. Its applicability to perinatal women with BSD is unclear.
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Mindfulness-based interventions are effective treatments for reducing symptoms of depression, anxiety, and stress in pregnant women.
“Mindfulness-based interventions (MBIs) have recently come into focus as effective treatments for reducing symptoms of depression, anxiety, and stress in the general population (41, 42) and in pregnant women (43–47), combining elements of CBT and psychoeducational content.”
From Acceptance, experiences, and needs of hospitalized pregnant women toward an electronic mindfulness-based intervention: A pilot mixed-methods study (2022) · cites this paper as [47]
The Discussion reports reduced self-rated depression symptoms in perinatal women with a history of major depression and calls MBCT a promising treatment. The Results report no change in anxiety scores; stress reduction was not assessed. The uncontrolled study included women planning pregnancy and postpartum as well as pregnant women, so it does not establish effectiveness for all pregnant women. (LLM, conf=0.90)
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- Authors
- Miklowitz, D. J., Semple, R. J., Hauser, M., Elkun, D., Weintraub, M. J., & Dimidjian, S.
- Affiliations
- University of California, Los Angeles (US)
- University of Colorado Boulder (US)
- Corresponding author
- Miklowitz, David J.
- Venue
- Cognitive Therapy and Research
- Published
- 2015-04-21
- Volume
- 39
- Issue
- 5
- Pages
- 590-600
- ISSN
- 0147-5916 (ISSN-L)
- 1573-2819
- PMC
- PMC7021274
- OpenAlex
- W2036962171
- Cited by
- 43
- References
- 42
- Citations by year
- 2026: 4 · 2024: 8 · 2023: 4 · 2022: 9 · 2021: 3 · 2020: 2 · 2018: 4 · 2017: 6 · 2016: 2 · 2015: 1
- FWCI
- 4.65
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Licence
- www.springer.com/tdm (tdm)
- Locations
- Cognitive Therapy and Research (publishedVersion)
- PubMed (publishedVersion)
- PubMed Central (acceptedVersion)
- eScholarship (California Digital Library) (submittedVersion)
- Funders
- National Institute of Mental Health (R01MH093676)
- Topics
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Maternal Mental Health During Pregnancy and Postpartum
- Social Sciences › Psychology › Clinical Psychology › Mindfulness and Compassion Interventions
- Social Sciences › Psychology › Clinical Psychology › Personality Disorders and Psychopathology
- Keywords
- mindfulness-based cognitive therapy, perinatal depression, bipolar spectrum disorders, major depressive disorder, perinatal mood disorders, postpartum depression, pregnancy, feasibility and acceptability, meditation, yoga, mood regulation
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