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GelMA combined with sustained release of HUVECs derived exosomes for promoting cutaneous wound healing and facilitating skin regeneration
Abstract
It remains a clinical challenge for cutaneous wound healing and skin regeneration. Endothelial cells participate in the formation of blood vessels and play an important role in the whole process of wound healing. Recent studies suggested that exosomes contribute to the intercellular communication through paracrine pathways, and sustained release of exosomes from hydrogel-based materials provide a promising strategy for curing wound defects. In this study, we isolated exosomes derived from human umbilical vein endothelial cells (HUVECs) and found that HUVECs derived exosomes (HUVECs-Exos) could promote the proliferation and migration activities of keratinocytes and fibroblasts, which are two important effector cells for skin regeneration. Then we developed gelatin methacryloyl (GelMA) hydrogel as the wound dressing to incorporate HUVECs-Exos and applied it to the full-thickness cutaneous wounds. It demonstrated that GelMA scaffold could not only repair the wound defect, but also achieve sustained release of exosomes. The in vivo results showed accelerated re-epithelialization, promotion of collagen maturity and improvement of angiogenesis. Collectively, our findings suggested that HUVECs-Exos could accelerate wound healing and GelMA mediated controlled release of HUVECs-Exos might offer a new method for repairing cutaneous wound defects.
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“For example, exosomes derived from human umbilical vein endothelial cells (HUVECs) can promote collagen maturation and angiogenesis and regulate the keratinocytes and fibroblast growth, thereby accelerating skin wound healing [102].”
From The Therapeutic Potential and Clinical Significance of Exosomes as Carriers of Drug Delivery System (2022) · cites this paper as [102]
Citations
Cites
2 retracted
Jianing, D., Wang, X., Chen, B., Zhang, J., & Xu, J. (2019) · BioMed Research International · doi:10.1155/2019/9742765 · Cited by 184
RetractedBarati, D., Shariati, S. R. P., Moeinzadeh, S., Melero‐Martin, J. M., Khademhosseini, A., & Jabbari, E. (2015) · Journal of Controlled Release · doi:10.1016/j.jconrel.2015.12.031 · Cited by 159
RetractedSinger, A. J., & Clark, R. A. F. (1999) · New England Journal of Medicine · doi:10.1056/nejm199909023411006 · Cited by 6,106
Communication by Extracellular Vesicles: Where We Are and Where We Need to Go
Tkach, M., & Théry, C. (2016) · Cell · doi:10.1016/j.cell.2016.01.043 · Cited by 3,444
Synthesis, properties, and biomedical applications of gelatin methacryloyl (GelMA) hydrogels
Yue, K., Trujillo-de Santiago, G., Alvarez, M. M., Tamayol, A., Annabi, N., & Khademhosseini, A. (2015) · Biomaterials · doi:10.1016/j.biomaterials.2015.08.045 · Cited by 3,146 · cited 4×
“…sequences of arginine-glycine-aspartic acid (RGD), which is favorable for cells attachment and proliferation on scaffold (Liu and Chan-Park 2010; Hadjizadeh and Doillon 2010), it also contains matrix metalloproteinase (MMP) sequences that help cells migration and remodeling (Yue 2015; Steen 2002).”
BackgroundMethodInfluentialJohnstone, R. M., Adam, M., Hammond, J. R., Orr, L., & Turbide, C. (1987) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)48095-7 · Cited by 2,931
The Wound Healing Process: An Overview of the Cellular and Molecular Mechanisms
Velnar, T., Bailey, T. A., & Smrkolj, V. (2009) · Journal of International Medical Research · doi:10.1177/147323000903700531 · Cited by 2,446
Transition from inflammation to proliferation: a critical step during wound healing
Landén, N. X., Li, D., & Ståhle, M. (2016) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-016-2268-0 · Cited by 1,980
Biomaterials based on chitin and chitosan in wound dressing applications
Jayakumar, R., Prabaharan, M., Kumar, P. T. S., Nair, S. V., & Tamura, H. (2011) · Biotechnology Advances · doi:10.1016/j.biotechadv.2011.01.005 · Cited by 1,927
Epithelialization in Wound Healing: A Comprehensive Review
Pastar, I., Stojadinović, O., Yin, N. C., Ramirez, H. A., Nusbaum, A. G., Sawaya, A. P., Patel, S. B., Khalid, L., Isseroff, R. R., & Tomic‐Canic, M. (2014) · Advances in Wound Care · doi:10.1089/wound.2013.0473 · Cited by 1,604
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Wang, Y., Cao, Z., Wei, Q., Ma, K., Hu, W., Huang, Q., Su, J., Li, H., Zhang, C., & Fu, X. (2022) · Acta Biomaterialia · doi:10.1016/j.actbio.2022.05.018 · Cited by 225
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Luo, L., He, Y., Jin, L., Zhang, Y., Guastaldi, F. P. S., Albashari, A. A., Hu, F., Wang, X., Wang, L., Xiao, J., et al. (2020) · Bioactive Materials · doi:10.1016/j.bioactmat.2020.08.028 · Cited by 128
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Li, S., Sun, J., Yang, J., Yang, Y., Ding, H., Yu, B., Ma, K., & Chen, M. (2023) · Biomaterials Research · doi:10.1186/s40824-023-00352-3 · Cited by 108
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Zheng, Y., Pan, C., Xu, P., & Liu, K. (2024) · Journal of Nanobiotechnology · doi:10.1186/s12951-024-02315-9 · Cited by 96
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Jing, Y., Ruan, L., Jiang, G., Nie, L., Shavandi, A., Sun, Y., Xu, J., Shao, X., & Zhu, J. (2023) · Biomaterials Advances · doi:10.1016/j.bioadv.2023.213405 · Cited by 49
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Yan, Z., Zhang, T., Wang, Y., Xiao, S., & Gao, J. (2023) · Materials Today Bio · doi:10.1016/j.mtbio.2023.100810 · Cited by 48
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Kong, X., Zhu, D., Hu, Y., Liu, C., Zhang, Y., Yu, W., Tan, J., Luo, Y., Chen, J., Xu, T., et al. (2024) · Materials & Design · doi:10.1016/j.matdes.2024.112717 · Cited by 39
Ellistasari, E. Y., Kariosentono, H., Purwanto, B., Wasita, B., Riswiyant, R. C. A., Pamungkasari, E. P., & Soetrisno, S. (2022) · Clinical Cosmetic and Investigational Dermatology · doi:10.2147/ccid.s371330 · Cited by 40
Zhu, J., Liu, Z., Wang, L., Jin, Q., Zhao, Y., Du, A., Ding, N., Wang, Y., Jiang, H., & Zhu, L. (2022) · Frontiers in Bioengineering and Biotechnology · doi:10.3389/fbioe.2022.866505 · Cited by 33
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Li, M., Yu, H., Ke, Q., Zhang, C., Gao, Y., & Guo, Y. (2021) · Journal of Materials Chemistry B · doi:10.1039/d1tb00449b · Cited by 30
Li, P., Zhang, M., Chen, Z., Tian, B., & Kang, X. (2023) · ACS Omega · doi:10.1021/acsomega.3c00211 · Cited by 31
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Yang, J., Zhang, X., Wang, G., Ma, S., Yu, Y., Liao, C., Wang, Z., Cheng, L., Li, M., Tian, W., et al. (2023) · International Journal of Nanomedicine · doi:10.2147/ijn.s436350 · Cited by 22
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Zhang, L., Shi, C., Lan, Y., Zhang, X., Ji, X., Li, L., He, X., Tan, Y., Zhao, N., & Lu, C. C. (2025) · International Journal of Nanomedicine · doi:10.2147/ijn.s542641 · Cited by 28
Deng, T., Zhang, Y., Yao, Y., Ye, P., Zhang, D., Cheng, F., Wu, J., Cheng, H., & Lu, J. G. (2025) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2025.118830 · Cited by 23
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Chen, A., Tian, H., Yang, N., Zhang, Z., Yang, G., Cui, W., & Tang, Y. (2022) · Extracellular Vesicles and Circulating Nucleic Acids · doi:10.20517/evcna.2022.37 · Cited by 22
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Huang, L., Shi, Y., Li, M., Wang, T., & Zhao, L. (2021) · Journal of Biomedical Nanotechnology · doi:10.1166/jbn.2021.3165 · Cited by 21
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Rezaei, S., Nilforoushzadeh, M. A., Amirkhani, M. A., Moghadasali, R., Taghiabadi, E., & Nasrabadi, D. (2024) · Molecular Pharmaceutics · doi:10.1021/acs.molpharmaceut.3c01121 · Cited by 22
Dou, Y., Hong, Z., Li, H., Xing, H., Zhu, C., & Xuan, Z. (2024) · Journal of Nanobiotechnology · doi:10.1186/s12951-024-02607-0 · Cited by 19
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Zhai, M., Tan, H., Xu, A., Wu, B., Xie, F., Lu, Y., & Zheng, Y. (2025) · Biomaterials Advances · doi:10.1016/j.bioadv.2025.214362 · Cited by 17
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Ash, M. E., Zibitt, M., Shauly, O., Menon, A., Losken, A., & Gould, D. J. (2024) · Aesthetic Surgery Journal Open Forum · doi:10.1093/asjof/ojae017 · Cited by 18
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Li, J., Tan, J., Song, Q., Yang, X., Zhang, X., Qin, H., Huang, G., Su, X., & Li, J. (2022) · Journal of Molecular Histology · doi:10.1007/s10735-022-10107-4 · Cited by 16
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Chen, T., Ellman, D. G., Fang, S., Bak, S. T., Nørgård, M. Ø., Svenningsen, P., & Andersen, D. C. (2024) · Theranostics · doi:10.7150/thno.91604 · Cited by 14
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Kaewsrisung, S., Sukpat, S., Isarasena, N., Patumraj, S., & Somboonwong, J. (2021) · Heliyon · doi:10.1016/j.heliyon.2021.e08533 · Cited by 13
Gao, F., Hu, Z., Xu, H., Yu, Y., Gao, S., Sun, J., He, G., & Peng, X. (2026) · Journal of Nanobiotechnology · doi:10.1186/s12951-026-04236-1 · Cited by 13
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Self-citationZhang, X., Hu, Y., Hao, D., Li, T., Jia, Y., Hu, W. P., & Xu, Z. (2022) · PubMed Central · Cited by 11
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Diverse Applications of Three-Dimensional Printing in Biomedical Engineering: A Review
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Shi, Y., Wang, R., Wang, L., Liu, Q., Han, L., Duan, X., Zhang, Y., Shen, A.-Z., Peng, D., Chen, W., et al. (2022) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2022.175477 · Cited by 9
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Sun, Z., Li, J., Wu, Z., Zhang, J., Wang, T., Zheng, Y., Xu, X., Ding, W., Qian, H., & Tan, Y. (2025) · Burns & Trauma · doi:10.1093/burnst/tkaf033 · Cited by 11
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Özhava, D., Bektas, C. K., Lee, K., Jackson, A., & Mao, Y. (2024) · Gels · doi:10.3390/gels10020097 · Cited by 9
Xiang, M., Guo, Q., Liu, Y., Zhang, G., Liao, C., Xiao, L., Xiang, M., Long, S., Long, Q., Guan, X., et al. (2025) · The FASEB Journal · doi:10.1096/fj.202402463r · Cited by 8
Ashique, S., Garg, A., Islam, A., Adhikary, K., Mantry, S., Kumar, S., Debnath, B., Yasmin, S., Mir, R. H., & Ansari, M. Y. (2025) · Tissue and Cell · doi:10.1016/j.tice.2025.103178 · Cited by 9
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Gao, Y., Li, X., Ding, Y., Wang, Y., Du, J., Chen, Y., Xu, J., & Liu, Y. F. (2025) · ACS Applied Materials & Interfaces · doi:10.1021/acsami.5c02551 · Cited by 8
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Ren, C., Chen, M., Ren, B., Zeng, Y., Tan, Q., Li, Q., Zhang, X. J., Fang, Y., Zhou, Y., Zhang, W., et al. (2024) · Neural Regeneration Research · doi:10.4103/nrr.nrr-d-23-02108 · Cited by 7
Self-citationYazicioglu, S., Arslan, T. S., Erdoğan, Y. K., Ercan, B., Arslan, Y. E., & Derkuş, B. (2026) · Macromolecular Bioscience · doi:10.1002/mabi.202500500 · Cited by 7
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Metadata
- Authors
- Zhao, D., Yu, Z., Li, Y., Wang, Y., Li, Q., & Han, D.
- Affiliations
- Shanghai Jiao Tong University (CN)
- Corresponding author
- Li, Qingfeng
- Han, Dong
- Venue
- Journal of Molecular Histology
- Published
- 2020-05-09
- Volume
- 51
- Issue
- 3
- Pages
- 251-263
- ISSN
- 1567-2379 (ISSN-L)
- 1567-2387
- OpenAlex
- W3023186039
- Cited by
- 139
- References
- 67
- Citations by year
- 2026: 15 · 2025: 21 · 2024: 27 · 2023: 27 · 2022: 31 · 2021: 16 · 2020: 2
- FWCI
- 10.53
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Journal of Molecular Histology (publishedVersion)
- PubMed (publishedVersion)
- Funders
- National Natural Science Foundation of China (81620108019, 81571944)
- Topics
- Health Sciences › Medicine › Surgery › Wound Healing and Treatments
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Extracellular vesicles in disease
- Physical Sciences › Materials Science › Biomaterials › Electrospun Nanofibers in Biomedical Applications
- Keywords
- exosomes, human umbilical vein endothelial cells, gelatin methacryloyl hydrogel, skin wound healing, skin regeneration, wound dressings, keratinocyte proliferation and migration, fibroblast proliferation and migration, re-epithelialization, collagen maturation, angiogenesis, paracrine signaling
- MeSH terms
- Animals, Cell Movement, Collagen, Fibroblasts, Humans, Male, Regeneration, Skin, Wound Healing, Keratinocytes, Rats, Sprague-Dawley, Neovascularization, Physiologic, Hydrogels, Cell Proliferation, Exosomes, Human Umbilical Vein Endothelial Cells, In Vitro Techniques
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