The efficacy of probiotic supplementation in rheumatoid arthritis: a meta-analysis of randomized, controlled trials
Abstract
Probiotics are considered as -immunomodulatory agents; their efficacy as an adjunct therapy option for rheumatoid arthritis (RA), however, remains controversial. The main aim of the present meta-analysis, therefore, was to compare available data from the published randomized, controlled trials (RCTs) recruiting adults with RA which compared probiotics with placebo. The English literature search was performed using Ovid version of Medline, EmBase, Web of Science, and the Central Cochrane library through October 2016 and supplemented by hand searching reference lists. Among 240 citations identified, 4 RCTs (153 participants; 89% female) were included. All data were pooled using a standardized mean difference (SMD) with a 95% CI. Compared to the placebo, probiotics did not change the inflammatory parameters (erythrocyte sedimentation rate, tumor necrosis factor [TNF]-α, interleukin [IL]-1β, IL-6, IL-10, and IL-12) and oxidative stress indices (total antioxidant capacity and malondialdehyde) significantly. The borderline significant reduction as a result of probiotic administration was only determined in C-reactive protein [SDM - 0.32 (95% CI - 0.65 to 0.00)]. Among disease activity indices (disease activity score [DAS], tender joint count, and swollen joint count), DAS showed a significant improvement following probiotic treatment with a SMD (95% CI) of - 0.58 (- 0.97 to - 0.19). The number of trials was too small to determine if a strain-, dose-, or duration-response effect was present. Probiotics seem to be less effective in RA; however, to reach a firm conclusion, we need further evidence.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
A recent meta-analysis of four probiotic trials in RA identified some improvement, but due to scarcity in data, further definitive research is needed.
“A recent meta-analysis of four probiotic trials in RA identified some improvement, however, due to a scarcity in data, further definitive research is needed (Aqaeinezhad Rudbane et al., 2018).”
From Viral Infections, the Microbiome, and Probiotics (2021) · cites this paper as Aqaeinezhad Rudbane et al., 2018
Cites
Probiotics: effects on immunity
Isolauri, E., Sütas, Y., Kankaanpää, P., Arvilommi, H. S., & Salminen, S. (2001) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/73.2.444s · Cited by 1,021 · see citing works
Beneficial Effects of a Probiotic VSL#3 on Parameters of Liver Dysfunction in Chronic Liver Diseases
Loguercio, C., Federico, A., Tuccillo, C., Terracciano, F., D’Auria, M. V., Simone, C. D., & Blanco, C. D. V. (2005) · Journal of Clinical Gastroenterology · doi:10.1097/01.mcg.0000165671.25272.0f · Cited by 448 · see citing works
Ejtahed, H., Mohtadinia, J., Rad, A. H., Niafar, M., Jafarabadi, M. A., Mofid, V., & Akbarian-Moghari, A. (2011) · Journal of Dairy Science · doi:10.3168/jds.2010-4128 · Cited by 416 · see citing works
Mandel, D. R., Eichas, K., & Holmes, J. (2010) · BMC Complementary and Alternative Medicine · doi:10.1186/1472-6882-10-1 · Cited by 408 · see citing works
Immunomodulatory Effects of Probiotics in the Intestinal Tract
Delcenserie, V., Martel, D., Lamoureux, M., Amiot, J., Boutin, Y., & Roy, D. (2008) · Current Issues in Molecular Biology · doi:10.21775/cimb.010.037 · Cited by 404 · see citing works
Probiotic supplementation improves inflammatory status in patients with rheumatoid arthritis
Vaghef‐Mehrabany, E., Alipour, B., Rad, A. H., Sharif, S., Jafarabadi, M. A., & Zavvari, S. (2013) · Nutrition · doi:10.1016/j.nut.2013.09.007 · Cited by 312 · see citing works
Alipour, B., Rad, A. H., Vaghef‐Mehrabany, E., Sharif, S., Vaghef‐Mehrabany, L., Jafarabadi, M. A., Nakhjavani, M. R. J., & Mohtadinia, J. (2014) · International Journal of Rheumatic Diseases · doi:10.1111/1756-185x.12333 · Cited by 244 · see citing works
Hatakka, K., Martio, J., Korpela, M. M., Herranen, M., Poussa, T. A., Laasanen, T., Saxelin, M., Vapaatalo, H., Moilanen, E., & Korpela, R. (2003) · Scandinavian Journal of Rheumatology · doi:10.1080/03009740310003695 · Cited by 235 · see citing works
Zamani, B., Golkar, H. R., Farshbaf, S., Emadi‐Baygi, M., Ebrahimi, M. T., Jafari, P., Akhavan, R., Taghizadeh, M., Memarzadeh, M. R., & Asemi, Z. (2016) · International Journal of Rheumatic Diseases · doi:10.1111/1756-185x.12888 · Cited by 220 · see citing works
Lomax, A. E., & Calder, P. C. (2009) · Current Pharmaceutical Design · doi:10.2174/138161209788168155 · Cited by 203 · see citing works
So, J., Kwon, H., Lee, C., Yi, H., Park, J., Lim, S., Hwang, K., Jeon, Y. H., & Im, S. (2008) · Molecular Immunology · doi:10.1016/j.molimm.2007.12.010 · Cited by 178 · see citing works
Pineda, M. D. L. A., Thompson, S. F., Summers, K., de Leon, F., Pope, J. E., & Reid, G. (2011) · Medical Science Monitor · doi:10.12659/msm.881808 · Cited by 169 · see citing works
Amdekar, S., Singh, V. K., Singh, R., Sharma, P., Keshav, P., & Kumar, A. (2010) · Journal of Clinical Immunology · doi:10.1007/s10875-010-9457-7 · Cited by 158 · see citing works
Uncooked, lactobacilli-rich, vegan food and rheumatoid arthritis
Nenonen, M., Helve, T., Rauma, A.-L., & Hänninen, O. (1998) · Lara D. Veeken · doi:10.1093/rheumatology/37.3.274 · Cited by 137 · see citing works
Influence of Dietary Components on Regulatory T Cells
Issazadeh‐Navikas, S., Teimer, R., & Bockermann, R. (2011) · Molecular Medicine · doi:10.2119/molmed.2011.00311 · Cited by 95 · see citing works
Vaghef-Mehrabany, E., Homayouni-Rad, A., Alipour, B., Sharif, S.-K., Vaghef-Mehrabany, L., & Alipour-Ajiry, S. (2016) · Journal of the American College of Nutrition · doi:10.1080/07315724.2014.959208 · Cited by 88 · see citing works
Amdekar, S., Singh, V. K., Kumar, A., Sharma, P., & Singh, R. (2012) · Journal of Interferon & Cytokine Research · doi:10.1089/jir.2012.0034 · Cited by 87 · see citing works
Malin, M., VERRONEN, P., Korhonen, H. J. T., Syväoja, E., Salminen, S., Mykkänen, H. M., Arvilommi, H. S., Eerola, E., & Isolauri, E. (1997) · Inflammopharmacology · doi:10.1007/s10787-997-0001-1 · Cited by 76 · see citing works
From reactive arthritis to rheumatoid arthritis
Toivanen, P. (2001) · Journal of Autoimmunity · doi:10.1006/jaut.2000.0496 · Cited by 42 · see citing works
Probiotic bacteria: a viable adjuvant therapy for relieving symptoms of rheumatoid arthritis
Wang, P., Tao, J., & Pan, H. (2016) · Inflammopharmacology · doi:10.1007/s10787-016-0277-0 · Cited by 39 · see citing works
Lee, H. J., WALLER, R. D., Stebbings, S. M., Highton, J., Orlovich, D. A., Schmierer, D. M., & Fawcett, J. P. (2009) · International Journal of Rheumatic Diseases · doi:10.1111/j.1756-185x.2009.01449.x · Cited by 34 · see citing works
[THE USE OF PROBIOTICS IN PATIENTS WITH RHEUMATOID ARTHRITIS].
Kuchmak, O. B., Klymnyuk, S. I., Romanyuk, L. B., & Pokryshko, O. (2014) · PubMed · Cited by 2 · see citing works
Пробіотикотерапія хворих на ревматоїдний артрит
Kuchmak, O. B., Klymnyuk, S. I., Romanyuk, L. B., & Pokryshko, O. (2014) · Likarska sprava · doi:10.31640/ls-2014-12-09 · Cited by 2 · see citing works
Flagged first, then by citations
Cited by
Sorted by citations
The gut–joint axis in rheumatoid arthritis
Zaiss, M. M., Wu, H.-J. J., Mauro, D., Schett, G. A., & Ciccia, F. (2021) · Nature Reviews Rheumatology · doi:10.1038/s41584-021-00585-3 · Cited by 394 · see citing works
Viral Infections, the Microbiome, and Probiotics
Harper, A., Vijayakumar, V., Ouwehand, A. C., ter Haar, J., Obis, D., Espadaler, J., Binda, S., Desiraju, S., & Day, R. (2021) · Frontiers in Cellular and Infection Microbiology · doi:10.3389/fcimb.2020.596166 · Cited by 177 · see citing works
Wadell, A. T., Bärebring, L., Hulander, E., Gjertsson, I., Lindqvist, H. M., & Winkvist, A. (2020) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/nqaa019 · Cited by 154 · see citing works
Diet, Microbiota, and Gut Permeability—The Unknown Triad in Rheumatoid Arthritis
Guerreiro, C. S., Calado, Â., Sousa, J., & Fonseca, J. E. (2018) · Frontiers in Medicine · doi:10.3389/fmed.2018.00349 · Cited by 133 · see citing works
Kazemi, A., Soltani, S., Ghorabi, S., Keshtkar, A., Daneshzad, E., Nasri, F., & Mazloomi, S. M. (2020) · Clinical Nutrition · doi:10.1016/j.clnu.2019.04.004 · Cited by 131 · see citing works
The effect of probiotics on inflammatory biomarkers: A meta-analysis of randomized clinical trials
Milajerdi, A., Mousavi, S. M., Sadeghi, A., Salari-Moghaddam, A., Parohan, M., Larijani, B., & Esmaillzadeh, A. (2020) · European Journal of Nutrition · doi:10.1007/s00394-019-01931-8 · Cited by 123 · see citing works
Probiotics: If It Does Not Help It Does Not Do Any Harm. Really?
Lerner, A., Shoenfeld, Y., & Matthias, T. (2019) · Microorganisms · doi:10.3390/microorganisms7040104 · Cited by 117 · see citing works
Amirani, E., Milajerdi, A., Mirzaei, H., Jamilian, H., Mansournia, M. A., Hallajzadeh, J., & Ghaderi, A. (2020) · Complementary Therapies in Medicine · doi:10.1016/j.ctim.2020.102361 · Cited by 118 · see citing works
Can Gut Microbiota Affect Dry Eye Syndrome?
Moon, J., Yoon, C. H., Choi, S. H., & Kim, M. K. (2020) · International Journal of Molecular Sciences · doi:10.3390/ijms21228443 · Cited by 98 · see citing works
Diet as a Modulator of Intestinal Microbiota in Rheumatoid Arthritis
Dourado, E., Ferro, M., Guerreiro, C. S., & Fonseca, J. E. (2020) · Nutrients · doi:10.3390/nu12113504 · Cited by 94 · see citing works
Babadi, M., Khorshidi, A., Aghadavod, E., Samimi, M., Kavossian, E., Bahmani, F., Mafi, A., Shafabakhsh, R., Sattari, M., & Asemi, Z. (2018) · Probiotics and Antimicrobial Proteins · doi:10.1007/s12602-018-9490-z · Cited by 80 · see citing works
Gwinnutt, J. M., Wieczorek, M., Rodríguez‐Carrio, J., Balanescu, A. R., Bischoff-Ferrari, H. A., Boonen, A. E. R. C. H., Cavalli, G., de Souza, S., de Thurah, A. L., Dorner, T. E., et al. (2022) · RMD Open · doi:10.1136/rmdopen-2021-002167 · Cited by 77 · see citing works
Longo, U. G., Lalli, A., Bandini, B., de Sire, R., Angeletti, S., Lustıg, S., Ammendolia, A., Budhiparama, N. C., & Alessandro de, S. I. R. E. (2024) · International Journal of Molecular Sciences · doi:10.3390/ijms25063242 · Cited by 83 · see citing works
Crossing the barriers: Revisiting the gut feeling in rheumatoid arthritis
Brandl, C., Bucci, L., Schett, G. A., & Zaiss, M. M. (2021) · European Journal of Immunology · doi:10.1002/eji.202048876 · Cited by 75 · see citing works
Ferro, M., Charneca, S., Dourado, E., Guerreiro, C. S., & Fonseca, J. E. (2021) · Frontiers in Pharmacology · doi:10.3389/fphar.2021.711788 · Cited by 75 · see citing works
Langan, D., Perkins, D. J., Vogel, S. N., & Moudgil, K. D. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22042017 · Cited by 70 · see citing works
Choi, S. H., Oh, J., Ryu, J. S., Kim, H. M., Im, S., Kim, K. P., & Kim, M. K. (2020) · Investigative Ophthalmology & Visual Science · doi:10.1167/iovs.61.3.42 · Cited by 68 · see citing works
Role of natural products in alleviation of rheumatoid arthritis—A review
Sharma, D., Chaubey, P., & Suvarna, V. (2021) · Journal of Food Biochemistry · doi:10.1111/jfbc.13673 · Cited by 64 · see citing works
Sanchez, P., Letarouilly, J.-G., Nguyen, Y., Sigaux, J., Barnetche, T., Czernichow, S., Flipo, R.-M., Sellam, J., & Daïen, C. (2022) · Nutrients · doi:10.3390/nu14020354 · Cited by 59 · see citing works
Postbiotic-Enabled Targeting of the Host-Microbiota-Pathogen Interface: Hints of Antibiotic Decline?
Puccetti, M., Xiroudaki, S., Ricci, M., & Giovagnoli, S. (2020) · Pharmaceutics · doi:10.3390/pharmaceutics12070624 · Cited by 70 · see citing works
Lifestyle Factors and Their Influence on Rheumatoid Arthritis: A Narrative Review
Schäfer, C., & Keyßer, G. (2022) · Journal of Clinical Medicine · doi:10.3390/jcm11237179 · Cited by 52 · see citing works
Zamani, B., Sheikhi, A., Namazi, N., Larijani, B. A., & Azadbakht, L. (2019) · Probiotics and Antimicrobial Proteins · doi:10.1007/s12602-018-9500-1 · Cited by 42 · see citing works
Faghfouri, A. H., Afrakoti, L. G. M. P., Kavyani, Z., Nogourani, Z. S., Musazadeh, V., Jafarlou, M., & Dehghan, P. (2023) · Inflammopharmacology · doi:10.1007/s10787-023-01332-8 · Cited by 41 · see citing works
Gut Microbiota Modulation: A Novel Strategy for Rheumatoid Arthritis Therapy
Chasov, V. V., Gilyazova, E., Ganeeva, I., Zmievskaya, E., Davletshin, D., Valiullina, A., & Bulatov, E. (2024) · Biomolecules · doi:10.3390/biom14121653 · Cited by 39 · see citing works
Musazadeh, V., Faghfouri, A. H., Zarezadeh, M., Pakmehr, A., Moghaddam, P. T., Hamedi, F., Jahandideh, A., & Ghoreishi, Z. (2023) · Frontiers in Nutrition · doi:10.3389/fnut.2023.1117387 · Cited by 38 · see citing works
Askari, G., Ghavami, A., Shahdadian, F., & Moravejolahkami, A. R. (2021) · Clinical Nutrition · doi:10.1016/j.clnu.2021.02.015 · Cited by 36 · see citing works
Gut-Microbiota Modulation: The Impact of theGut-Microbiotaon Osteoarthritis.
Arora, V., Singh, G., O-Sullivan, I., Ma, K., Anbazhagan, A. N., Gott-Velis, G., Bruce, B., Richard, R., Wijnen, A. J., & Im, H. (2021) · Gene · doi:10.1016/j.gene.2021.145619 · Cited by 31 · see citing works
A systematic review of the effects of probiotic administration in inflammatory arthritis
Lowe, J. R., Briggs, A. M., Whittle, S., & Stephenson, M. (2020) · Complementary Therapies in Clinical Practice · doi:10.1016/j.ctcp.2020.101207 · Cited by 31 · see citing works
DMARDs–Gut Microbiota Feedback: Implications in the Response to Therapy
Zaragoza-García, Ó., Castro-Alarcón, N., Pérez-Rubio, G., & Guzmán‐Guzmán, I. P. (2020) · Biomolecules · doi:10.3390/biom10111479 · Cited by 31 · see citing works
MAIT Cells and Microbiota in Multiple Sclerosis and Other Autoimmune Diseases
Mechelli, R., Romano, S., Romano, C., Morena, E., Buscarinu, M. C., Bigi, R., Bellucci, G., Reniè, R., Pellicciari, G., Salvetti, M., et al. (2021) · Microorganisms · doi:10.3390/microorganisms9061132 · Cited by 24 · see citing works
Blenkinsopp, H. C., Seidler, K., & Barrow, M. (2023) · Journal of the American Nutrition Association · doi:10.1080/27697061.2023.2211129 · Cited by 20 · see citing works
Pružinská, K., Slovák, L., Dráfi, F., Poništ, S., Juránek, I., Chrastina, M., Švík, K., Strojný, L., Ambro, Ľ., & Bauerová, K. (2022) · Molecules · doi:10.3390/molecules28010297 · Cited by 16 · see citing works
Probiotics in Allergy and Immunological Diseases: A Comprehensive Review
Vijayan, S., Kandi, V., Palacholla, P. S., Rajendran, R., Jarugu, C., Jayashankar, C. A., Pravallika, M., Reddy, S. C., & Sucharitha, A. S. (2024) · Cureus · doi:10.7759/cureus.55817 · Cited by 13 · see citing works
Gusakov, K. I., Kalinkovich, A., Ashkenazi, S., & Livshits, G. (2024) · Nutrients · doi:10.3390/nu16152569 · Cited by 13 · see citing works
Probiotic Use and Psoriatic Arthritis Disease Activity
Grinnell, M., Ogdie, A., Wipfler, K., & Michaud, K. D. (2020) · ACR Open Rheumatology · doi:10.1002/acr2.11143 · Cited by 12 · see citing works
Eor, J. Y., Park, N., Son, Y. J., & Kim, S. H. (2021) · Food Science of Animal Resources · doi:10.5851/kosfa.2021.e13 · Cited by 11 · see citing works
Effect of Probiotic Consumption on Immune Response in Athletes: A Meta-analysis
Tavakoly, R., Hadi, A., Rafie, N., Talaei, B., Marx, W., & Arab, A. (2021) · International Journal of Sports Medicine · doi:10.1055/a-1463-3303 · Cited by 11 · see citing works
Modulation of autoimmune arthritis by environmental ‘hygiene’ and commensal microbiota
Langan, D., Kim, E. Y., & Moudgil, K. D. (2018) · Cellular Immunology · doi:10.1016/j.cellimm.2018.12.005 · Cited by 11 · see citing works
Mohammadi, F., Razmjooei, N., Mohsenpour, M. A., Nejati, M. A., Eftekhari, M. H., & Hejazi, N. (2025) · BMC Nutrition · doi:10.1186/s40795-024-00989-w · Cited by 12 · see citing works
Li, W., Zhang, Y., Guo, D., Gong, R., Yuan, J., & Yang, H. (2024) · Frontiers in Immunology · doi:10.3389/fimmu.2024.1397716 · Cited by 8 · see citing works
Chen, S., Hoàng, M. H., Hu, D., He, Q., & Gao, Y. (2026) · Annals of Medicine · doi:10.1080/07853890.2026.2613484 · Cited by 8 · see citing works
Xia, Q., Lei, Y., Wang, J., & Wang, Q. (2023) · Open Life Sciences · doi:10.1515/biol-2022-0741 · Cited by 8 · see citing works
Probiotics as Live Bio-therapeutics: Prospects and Perspectives
Kaur, J., Singh, B. P., Chaudhary, V., Elshaghabee, F. M. F., Singh, J., Singh, A., Rokana, N., & Panwar, H. (2020) · Microorganisms for sustainability · doi:10.1007/978-981-15-6795-7_5 · Cited by 8 · see citing works
Therapeutic alteration of the microbiota in rheumatic diseases: Hype or potential?
Stoll, M. L. (2022) · Best Practice & Research Clinical Rheumatology · doi:10.1016/j.berh.2022.101806 · Cited by 8 · see citing works
Palmowski, A., & Nielsen, S. M. (2019) · Inflammopharmacology · doi:10.1007/s10787-019-00606-4 · Cited by 7 · see citing works
Probiotics and prebiotics in the suppression of autoimmune diseases
Giri, P. S., Shah, F., & Dwivedi, M. (2021) · Elsevier eBooks · doi:10.1016/b978-0-12-823733-5.00019-2 · Cited by 6 · see citing works
The role of gut flora-driven Th cell responses in preclinical rheumatoid arthritis
Chen, S., Dan, L., Li, X., He, Q., Hu, D., & Gao, Y. (2025) · Journal of Autoimmunity · doi:10.1016/j.jaut.2025.103426 · Cited by 5 · see citing works
Impact of Nutritional Diet Therapy on Rheumatoid Arthritis Disease Activity
Deseatnicova, E., Covaliov, E., Deseatnicova, O., Siminiuc, R., Rezuş, E., & Groppa, L. (2026) · Nutrients · doi:10.3390/nu18030517 · Cited by 4 · see citing works
Microbiota and arthritis: cause or consequence?
Cafaro, G., Cruciani, G., Bruno, L., Pozzolo, R. D., Colangelo, A., Tromby, F., Nicchi, M., Pianese, B., Perricone, C., Gerli, R., et al. (2024) · Clinical and Experimental Rheumatology · doi:10.55563/clinexprheumatol/f6q4dc · Cited by 4 · see citing works
Mechanistic insights into gut microbiota–driven autoimmunity in rheumatoid arthritis
Li, J., Chen, X., & Xie, X. (2026) · Frontiers in Immunology · doi:10.3389/fimmu.2026.1812972 · Cited by 3 · see citing works
Kragsnæs, M. S., Gilbert, B. T. P., Sofíudóttir, B. K., Rooney, C. M., Hansen, S. M.-B., Mauro, D., Mullish, B. H., Bergot, A., Mankia, K. S., Goel, N., et al. (2025) · BMJ Open · doi:10.1136/bmjopen-2025-101593 · Cited by 3 · see citing works
Scott, I. C., Smith, T. M., Babatunde, O. O., Barker, C., Battista, S., Beesley, R., Beesley, R. P., Birkinshaw, H., Brooke, M., Chaplin, H., et al. (2026) · Rheumatology · doi:10.1093/rheumatology/keag320 · Cited by 2 · see citing works
Herbs and dietary supplements in rheumatoid arthritis: The clinical evidence
Clement, Y. N. (2022) · West Indian Journal of Immunology · doi:10.53069/wiji/0000002 · Cited by 1 · see citing works
Dietary, Herbal and Nutritional Interventions for Managing Rheumatoid Arthritis: A Review
Verma, A., Dubey, N., Agrawal, A., & Goyal, A. (2023) · Current Pharmaceutical Biotechnology · doi:10.2174/1389201024666230807155529 · Cited by 2 · see citing works
Ernährung bei rheumatischen Erkrankungen
Keyßer, G. (2018) · Arthritis und Rheuma · doi:10.1055/s-0038-1669793 · Cited by 1 · see citing works
Probiotics and autoimmunity: Current evidence
Shamriz, O. (2018) · Autoimmunity Reviews · doi:10.1016/j.autrev.2018.06.005 · Cited by 1 · see citing works
AN EVALUATION OF DIETARY APPROACHES USED IN THE CLINICAL MANAGEMENT OF RHEUMATOID ARTHRITIS
Dengizek, M. S., & Yeşilkaya, B. Y. (2023) · Kocatepe tıp dergisi. · doi:10.18229/kocatepetip.845249 · Cited by 1 · see citing works
Han, M., Zhang, N., Peng, Z., Mao, Y., Yang, Q., Chen, Y., Ren, M., & Jia, W. (2023) · Translational bioinformatics · doi:10.1007/978-981-19-8210-1_6 · Cited by 1 · see citing works
Schäfer, C., Keyßer, G., & Reuss-Borst, M. A. (2024) · Zeitschrift für Rheumatologie · doi:10.1007/s00393-024-01559-y · Cited by 1 · see citing works
Харчування як чинник ризику та втручання при ревматичних захворюваннях
Puzanovа, О. G. (2019) · PAIN JOINTS SPINE · doi:10.22141/2224-1507.9.3.2019.178640 · Cited by 1 · see citing works
Microorganisms in Pathogenesis and Management of Rheumatoid Arthritis
Balakrishnan, B., & Taneja, V. (2022) · Springer eBooks · doi:10.1007/978-981-19-1946-6_16 · Cited by 1 · see citing works
Mason, A., & Malik, M. (2020) · EMJ Rheumatology · doi:10.33590/emjrheumatol/20-00098
Probiotics for immune disease prevention and treatment
Pelúzio, M. D. C. G., Rosa, C. D. O. B., Pereira, M. D. F. A., Dias, M. D. M. E., Bernardes, A. L., Cruz, B. C. D. S., Milagro, F. I., & Bressan, J. (2022) · Elsevier eBooks · doi:10.1016/b978-0-323-89908-6.00004-2
Microbiome and Leaky Gut Syndrome as Extra-articular Factors for Rheumatoid Arthritis
Chernyavskyi, V. V., Postemska, M., & Reshotko, D. O. (2022) · Family medicine European practices · doi:10.30841/2786-720x.4.2022.274650
Ernährung bei Rheumatoider Arthritis: Ihr Einfluss auf Erkrankungsrisiko und Krankheitsverlauf
Keyßer, G., & Reuss-Borst, M. A. (2023) · Aktuelle Rheumatologie · doi:10.1055/a-2113-5751
Kebede, B., & Tilahun, A. (2024) · American Journal of Bioscience and Bioengineering · doi:10.11648/j.bio.20241206.12
Iqbal, G., Nazar, T., Aziz, B., Fatima, T., Imran, Y., & Islam, A. (2024) · Pakistan Journal of Health Sciences · doi:10.54393/pjhs.v5i12.2241
Schäfer, C., Keyßer, G., & Reuss-Borst, M. A. (2025) · Rheuma Plus / Schweiz · doi:10.1007/s44332-025-00051-2
Chiou, Y., Chiu, T.-Y., & Chen, M.-J. (2026) · Nutrients · doi:10.3390/nu18071107
- Authors
- Aqaeinezhad Rudbane, S. M., Rahmdel, S., Abdollahzadeh, S. M., Zare, M., Bazrafshan, A., & Mazloomi, S. M.
- Affiliations
- Shiraz University (IR)
- Shiraz University of Medical Sciences (IR)
- Kerman University of Medical Sciences (IR)
- Corresponding author
- Abdollahzadeh, Seyedeh Maryam
- ORCID
- Venue
- Inflammopharmacology
- Published
- 2018-01-04
- Volume
- 26
- Issue
- 1
- Pages
- 67-76
- ISSN
- 0925-4692 (ISSN-L)
- 1568-5608
- OpenAlex
- W2781848730
- Cited by
- 69
- References
- 23
- Citations by year
- 2026: 5 · 2025: 4 · 2024: 9 · 2023: 8 · 2022: 9 · 2021: 12 · 2020: 11 · 2019: 6 · 2018: 5
- FWCI
- 0.86
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Inflammopharmacology (publishedVersion)
- PubMed (publishedVersion)
- Research Information System of Ardabil University of Medical Sciences (Ardabil University of Medical Sciences) (submittedVersion)
- Funders
- Shiraz University of Medical Sciences (95-01-106-12747)
- Topics
- Life Sciences › Agricultural and Biological Sciences › Food Science › Probiotics and Fermented Foods
- Health Sciences › Medicine › Rheumatology › Rheumatoid Arthritis Research and Therapies
- Health Sciences › Medicine › Complementary and alternative medicine › Natural Compounds in Disease Treatment
- Keywords
- probiotics, rheumatoid arthritis, adjunctive therapy, disease activity, C-reactive protein, inflammatory cytokines, oxidative stress, immunomodulation, placebo comparison
- MeSH terms
- Adult, Aged, Aged, 80 and over, Arthritis, Rheumatoid, C-Reactive Protein, Erythrocytes, Female, Humans, Immunologic Factors, Inflammation, Interleukins, Male, Malondialdehyde, Middle Aged, Tumor Necrosis Factor-alpha, Randomized Controlled Trials as Topic, Antirheumatic Agents, Dietary Supplements, Probiotics, Young Adult
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
