Cited by 284Gambling Behavior and TreatmentsSubstance Abuse Treatment and OutcomesNeural and Behavioral Psychology Studies

A Systematic Meta-Review of Impulsivity and Compulsivity in Addictive Behaviors

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Lee, Rico S. C., Hoppenbrouwers, Sylco, Franken, Ingmar·2019·Neuropsychology Review

Abstract

It is well established that poor inhibitory control confers both a vulnerability to, and maintenance of, addictive behaviors across the substance and behavioral spectrums. By comparison, the role of compulsivity in addictive behaviors has received less research focus. The neurocognitive literature to date is vast, and it is unclear whether there are any convincing lines of systematic evidence delineating whether and how aspects of impulsivity and compulsivity are shared and unique across different substance and behavioral addictive disorders. Such information has significant implications for our understanding of underlying mechanisms and clinical implications for assessing and treating neurocognitive deficits across addictions. Here, we conducted a systematic meta-review of the quantitative meta-analyses to date, specifically examining the neurocognitive functions central to impulsive-compulsive behaviors transdiagnostically across addictive behaviors. Out of 1186 empirical studies initially identified, six meta-analyses met inclusion criteria examining alcohol, cannabis, cocaine, MDMA, methamphetamine, opioid and tobacco use, as well as gambling and internet addiction. The pooled findings across the systematic meta-analyses suggest that impulsivity is a core process underpinning both substance and behavioral addictive disorders, although it is not equally implicated across all substances. Compulsivity-related neurocognition, by comparison, is important across alcohol and gambling disorders, but has yet to be examined systematically. The gestalt of findings to date suggests that both impulsivity and compulsivity are core constructs linked to addictive behaviors and may not be solely the secondary sequelae associated with the effects of prolonged substance exposure.

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  1. Cuthbert, B. N. (2014). The RDoC framework: Facilitating transition from ICD/DSM to dimensional approaches that integrate neurosci- ence and psychopathology. World Psychiatry, 13(1), 28-35.

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Authors
Lee, R. S. C., Hoppenbrouwers, S., & Franken, I.
Affiliations
  • Monash University (AU)
  • Erasmus University Rotterdam (NL)
Corresponding author
Lee, Rico S. C.
Venue
Neuropsychology Review
Published
2019-03
Volume
29
Issue
1
Pages
14-26
ISSN
  • 1040-7308 (ISSN-L)
  • 1573-6660
OpenAlex
W2934941373
Cited by
284
References
60
Citations by year
2026: 39 · 2025: 44 · 2024: 48 · 2023: 40 · 2022: 34 · 2021: 47 · 2020: 24 · 2019: 7 · 2012: 1
FWCI
4.43
Type
journal article
Language
en
Open access
Locations
  • Neuropsychology Review (publishedVersion)
  • PubMed (publishedVersion)
  • EUR Research Repository (Erasmus University Rotterdam) (publishedVersion, other-oa)
  • EUR Research Repository (Erasmus University Rotterdam) (submittedVersion, other-oa)
Topics
  • Social Sciences › Psychology › Clinical Psychology › Gambling Behavior and Treatments
  • Health Sciences › Medicine › Epidemiology › Substance Abuse Treatment and Outcomes
  • Life Sciences › Neuroscience › Cognitive Neuroscience › Neural and Behavioral Psychology Studies
Keywords
impulsivity, compulsivity, addictive behavior, substance use disorders, behavioral addiction, neurocognitive impairment, inhibitory control, alcoholism, gambling addiction, internet addiction, transdiagnostic mechanisms
MeSH terms
Compulsive Behavior, Humans, Impulsive Behavior, Inhibition, Psychological, Neuropsychological Tests, Behavior, Addictive, Executive Function

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