LC-MS metabolomics top-down approach reveals new exposure and effect biomarkers of apple and apple-pectin intake
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In dietary intervention studies with single foods, the contrast for a good biomarker can be large, sometimes infinite, allowing robust work with small sample sets and discrimination of potential intake biomarkers from subtle changes in endogenous metabolites.
“In dietary intervention studies with single foods, the contrast observed for a good biomarker can be large, sometimes even infinite, making it possible to work robustly with small sample sets and discriminate potential intake biomarkers from more subtle changes in endogenous metabolites (126).”
From The food metabolome: a window over dietary exposure (2014) · cites this paper as [126]
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- Authors
- Kristensen, M., Engelsen, S. B., & Dragsted, L. O.
- Affiliations
- University of Copenhagen (DK)
- Corresponding author
- Kristensen, Mette
- Venue
- Metabolomics
- Published
- 2011-02-13
- Volume
- 8
- Issue
- 1
- Pages
- 64-73
- ISSN
- 1573-3882 (ISSN-L)
- 1573-3890
- OpenAlex
- W1995658976
- Cited by
- 47
- References
- 34
- Citations by year
- 2026: 1 · 2024: 1 · 2023: 3 · 2022: 1 · 2021: 2 · 2020: 4 · 2019: 3 · 2018: 4 · 2017: 2 · 2016: 5 · 2015: 3 · 2014: 8 · 2013: 9 · 2012: 1
- FWCI
- 2.33
- Type
- journal article
- Language
- en
- Open access
- closed
- Licence
- www.springer.com/tdm (tdm)
- Locations
- Metabolomics (publishedVersion)
- Research at the University of Copenhagen (University of Copenhagen) (submittedVersion)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Metabolomics and Mass Spectrometry Studies
- Health Sciences › Medicine › Biochemistry › Phytochemicals and Antioxidant Activities
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diet, Metabolism, and Disease
- Keywords
- apple pectin, dietary fiber, urinary metabolome, biomarkers of exposure, biomarkers of effect, quinic acid, m-coumaric acid, epicatechin, hippuric acid, pyrrole-2-carboxylic acid, 2-piperidinone, rats
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