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Candidate rejuvenating factor GDF11 and tissue fibrosis: friend or foe?
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“the cytokine GDF11 rejuvenates some tissues, such as muscle, brain and endocrine pancreas, although it impairs the function and repair of other tissues due to its pro-fibrotic side effects 241 ;”
From Hallmarks of aging: An expanding universe (2023) · cites this paper as [241]
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“| Altered intercellular communication | Mouse | GDF11 i.v. administration | Rejuvenation of brain, muscle and pancreas, but profibrotic effects | 241”
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Hallmarks of aging: An expanding universe
López-Otín, C., Blasco, M. A., Partridge, L., Serrano, M., & Kroemer, G. (2023) · Cell · doi:10.1016/j.cell.2022.11.001 · Cited by 6,549
Metadata
- Authors
- Frohlich, J., & Vinciguerra, M.
- ORCID
- Vinciguerra, Manlio
- Venue
- GeroScience
- Published
- 2020-10-06
- Volume
- 42
- Issue
- 6
- Pages
- 1475-1498
- ISSN
- 2509-2715
- 2509-2723
- Cited by
- 28
- References
- 19
- Language
- en
- Funders
- European Social Fund and European Regional Development Fund (CZ.02.1.01/0.0/0.0/15_003/0000492)
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