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Ursodeoxycholic Acid in the Prevention of Gallstone Formation After Bariatric Surgery: an Updated Systematic Review and Meta-analysis
Abstract
We aim to review the available literature on obese patients treated with ursodeoxycholic acid (UDCA) in order to prevent gallstone formation after bariatric surgery. A systematic literature search was performed in PubMed, Cochrane library, and Scopus databases, in accordance with the PRISMA guidelines. Eight studies met the inclusion criteria incorporating 1355 patients. Random-effects meta-analysis showed a lower incidence of gallstone formation in patients taking UDCA. Subgroup analysis reported fewer cases of gallstone disease in the UDCA group in relation to different bariatric procedures, doses of administered UDCA, and time from bariatric surgery. Adverse events were similar in both groups. Fewer patients required cholecystectomy in UDCA group. No deaths were reported. The administration of UDCA after bariatric surgery seems to prevent gallstone formation.
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“Consequently, similar incidences of symptomatic gallstone disease, 40 and a similar effect of ursodeoxycholic acid on gallstone formation are reported.7,23,24,26”
In the citing paper
“A meta-analysis of 6 RCTs and two observational studies found that ursodeoxycholic acid treatment versus no treatment was associated with lower odds of gallstone formation (OR 0.20, 95% CI 0.13 to 0.33) [129].”
From Clinical practice guidelines of the European Association for Endoscopic Surgery (EAES) on bariatric surgery: update 2020 endorsed by IFSO-EC, EASO and ESPCOP (2020) · cites this paper as [129]
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Cites
Bias in meta-analysis detected by a simple, graphical test
Egger, M., Smith, G. D., Schneider, M., & Minder, C. (1997) · BMJ · doi:10.1136/bmj.315.7109.629 · Cited by 56,722
Liberati, A., Altman, D. G., Tetzlaff, J., Mulrow, C., Gøtzsche, P. C., Ioannidis, J. P. A., Clarke, M., Devereaux, P. J., Kleijnen, J., & Moher, D. (2009) · PLoS Medicine · doi:10.1371/journal.pmed.1000100 · Cited by 28,164
Stang, A. (2010) · European Journal of Epidemiology · doi:10.1007/s10654-010-9491-z · Cited by 17,396
Borenstein, M., Hedges, L. V., Higgins, J. P. T., & Rothstein, H. R. (2009) · doi:10.1002/9780470743386 · Cited by 14,225
Borenstein, M., Hedges, L. V., Higgins, J. P. T., & Rothstein, H. R. (2021) · doi:10.1002/9781119558378 · Cited by 9,799
Cochrane Handbook for Systematic Reviews of Interventions Version 5.0.1. The Cochrane Collaboration
Higgins, J., Green, S. R., & Higgins, J. (2008) · Cited by 5,544
Heart Disease and Stroke Statistics—2013 Update: A Report From the American Heart Association
Go, A. S., Mozaffarian, D., Roger, V. L., Benjamin, E. J., Berry, J. D., Borden, W. B., Bravata, D. M., Dai, S., Ford, E. S., Fox, C. S., et al. (2013) · Circulation · doi:10.1161/cir.0b013e31828124ad · Cited by 5,292
Go, A. S., Mozaffarian, D., Roger, V. L., Benjamin, E. J., Berry, J. D., Borden, W. B., Bravata, D. M., Dai, S., Ford, E. S., Fox, C. S., et al. (2013) · Circulation · doi:10.1161/cir.0b013e318282ab8f · Cited by 1,294
Burden of Digestive Diseases in the United States Part III: Liver, Biliary Tract, and Pancreas
Everhart, J. E., & Ruhl, C. E. (2009) · Gastroenterology · doi:10.1053/j.gastro.2009.02.038 · Cited by 710
Colquitt, J. L., Picot, J., Loveman, E., & Clegg, A. J. (2009) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd003641.pub3 · Cited by 650
Natural history of asymptomatic and symptomatic gallstones
FRIEDMAN, G. D. (1993) · The American Journal of Surgery · doi:10.1016/s0002-9610(05)80930-4 · Cited by 453
Risk of symptomatic gallstones in women with severe obesity
Stampfer, M. J., Maclure, K., Colditz, G. A., Manson, J., & Willett, W. C. (1992) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/55.3.652 · Cited by 357
Sugerman, H. J., Brewer, W. H., Shiffman, M. L., Brolin, R. E., Fobi, M. A. L., Linner, J. H., MacDonald, K. G., MacGregor, A. M., Martin, L. F., Oram-Smith, J. C., et al. (1995) · The American Journal of Surgery · doi:10.1016/s0002-9610(99)80115-9 · Cited by 336
Broomfield, P. H., Chopra, R., Sheinbaum, R. C., Bonorris, G. G., Silverman, A., Schoenfield, L. J., & Marks, J. W. (1988) · New England Journal of Medicine · doi:10.1056/nejm198812153192403 · Cited by 222
Miller, K., Hell, E., Lang, B., & Lengauer, E. (2003) · Annals of Surgery · doi:10.1097/01.sla.0000094305.77843.cf · Cited by 200
Magouliotis, D. E., Tasiopoulou, V. S., Sioka, E., Chatedaki, C., & Zacharoulis, D. (2017) · Obesity Surgery · doi:10.1007/s11695-017-2595-8 · Cited by 157
Self-citationWudel, L. J., Wright, J. K., Debelak, J. P., Allos, T. M., Shyr, Y., & Chapman, W. C. (2002) · Journal of Surgical Research · doi:10.1006/jsre.2001.6322 · Cited by 154
Uy, M. C., Talingdan-Te, M. C., Espinosa, W. Z., Daez, M. L. O., & Ong, J. P. (2008) · Obesity Surgery · doi:10.1007/s11695-008-9587-7 · Cited by 133
Tucker, O., Fajnwaks, P., Szomstein, S., & Rosenthal, R. J. (2008) · Surgical Endoscopy · doi:10.1007/s00464-008-9769-3 · Cited by 113
Salvioli, G., Igimi, H., & Carey, M. C. (1983) · Journal of Lipid Research · doi:10.1016/s0022-2275(20)37948-7 · Cited by 110
Moon, R. C., Teixeira, A. F., DuCoin, C. G., Varnadore, S., & Jawad, M. A. (2013) · Surgery for Obesity and Related Diseases · doi:10.1016/j.soard.2013.04.019 · Cited by 92
Worobetz, L., Inglis, F. G., & Shaffer, E. A. (1993) · PubMed · Cited by 85
Swartz, D. E., & Felix, E. L. (2005) · Surgery for Obesity and Related Diseases · doi:10.1016/j.soard.2005.08.002 · Cited by 75
Magouliotis, D. E., Tasiopoulou, V. S., Sioka, E., & Zacharoulis, D. (2016) · Obesity Surgery · doi:10.1007/s11695-016-2444-1 · Cited by 75
Self-citationAdams, L. B., Chang, C., Pope, J., Kim, Y., Liu, P., & Yates, A. (2016) · Obesity Surgery · doi:10.1007/s11695-015-1858-5 · Cited by 71
Magouliotis, D. E., Tasiopoulou, V. S., Svokos, A. A., Svokos, K. A., Sioka, E., & Zacharoulis, D. (2017) · Obesity Surgery · doi:10.1007/s11695-017-2807-2 · Cited by 65
Self-citationCaruana, J. A., McCabe, M. N., Smith, A. D., Camara, D. S., Mercer, M. A., & Gillespie, J. A. (2005) · Surgery for Obesity and Related Diseases · doi:10.1016/j.soard.2005.08.004 · Cited by 64
Papasavas, P. K., Gagné, D. J., Ceppa, F. A., & Caushaj, P. F. (2006) · Surgery for Obesity and Related Diseases · doi:10.1016/j.soard.2005.10.006 · Cited by 58
Coupaye, M., Calabrese, D., Sami, O., Msika, S., & Ledoux, S. (2017) · Surgery for Obesity and Related Diseases · doi:10.1016/j.soard.2016.11.022 · Cited by 58
Cholecystectomy after gastric bypass—incidence and complications
Wanjura, V., Sandblom, G., Österberg, J., Enochsson, L., Ottosson, J., & Szabó, É. (2016) · Surgery for Obesity and Related Diseases · doi:10.1016/j.soard.2016.12.004 · Cited by 56
Safety and efficacy of simultaneous cholecystectomy at Roux-en-Y gastric bypass
Kim, J.-J., & Schirmer, B. (2009) · Surgery for Obesity and Related Diseases · doi:10.1016/j.soard.2008.06.001 · Cited by 45
Abdallah, E., Emile, S. H., Elfeki, H., Fikry, M., Abdelshafy, M., Elshobaky, A., Elgendy, H., Thabet, W., Youssef, M., Elghadban, H., et al. (2017) · Surgery Today · doi:10.1007/s00595-016-1446-x · Cited by 44
Williams, C. N., Gowan, R., & Perey, B. J. (1993) · Obesity Surgery · doi:10.1381/096089293765559278 · Cited by 41
Dorman, R. B., Zhong, W., Abraham, A. A., Ikramuddin, S., Al‐Refaie, W. B., Leslie, D. B., & Habermann, E. B. (2013) · Obesity Surgery · doi:10.1007/s11695-013-1001-4 · Cited by 32
Concomitant cholecystectomy should be routinely performed with laparoscopic Roux-en-Y gastric bypass
Weiss, A. C., Inui, T., Parina, R., Coker, A. M., Jacobsen, G. R., Horgan, S., Talamini, M. A., Chang, D. C., & Sandler, B. J. (2014) · Surgical Endoscopy · doi:10.1007/s00464-014-4033-5 · Cited by 29
Sarr, M. G. (2006) · Surgery for Obesity and Related Diseases · doi:10.1016/j.soard.2006.01.011 · Cited by 5
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Mechanick, J. I., Apovian, C., Brethauer, S., Garvey, W. T., Joffe, A. M., Kim, J., Kushner, R. F., Lindquist, R., Pessah-Pollack, R., Seger, J., et al. (2020) · Surgery for Obesity and Related Diseases · doi:10.1016/j.soard.2019.10.025 · Cited by 608
Stenberg, E., Falcão, L. F. D. R., O’Kane, M. P. M., Liem, R. S. L., Pournaras, D. J., Salminen, P. T. P., Urman, R. D., Wadhwa, A. N., Gustafsson, U. O., & Thorell, A. (2022) · World Journal of Surgery · doi:10.1007/s00268-021-06394-9 · Cited by 551
Mechanick, J. I., Apovian, C., Brethauer, S., Garvey, W. T., Joffe, A. M., Kim, J., Kushner, R. F., Lindquist, R., Pessah-Pollack, R., Seger, J., et al. (2019) · Endocrine Practice · doi:10.4158/gl-2019-0406 · Cited by 510
Di Lorenzo, N., Antoniou, S. A., Batterham, R. L., Busetto, L., Godoroja, D., Iossa, A., Carrano, F. M., Agresta, F., Alarçon, I., Azran, C., et al. (2020) · Surgical Endoscopy · doi:10.1007/s00464-020-07555-y · Cited by 465
Mechanick, J. I., Apovian, C. M., Brethauer, S. A., Garvey, W. T., Joffe, A. M., Kim, J. J., Kushner, R. F., Lindquist, R., Pessah‐Pollack, R., Seger, J., et al. (2020) · Obesity · doi:10.1002/oby.22719 · Cited by 425
Metadata
- Authors
- Magouliotis, D. E., Tasiopoulou, V. S., Svokos, A. A., Svokos, K. A., Chatedaki, C., Sioka, E., & Zacharoulis, D.
- Affiliations
- University Hospital of Larissa (GR)
- University of Thessaly (GR)
- Riverside Regional Medical Center (US)
- Brown University (US)
- Corresponding author
- Magouliotis, Dimitrios E.
- ORCID
- Venue
- Obesity Surgery
- Published
- 2017-09-09
- Volume
- 27
- Issue
- 11
- Pages
- 3021-3030
- ISSN
- 0960-8923 (ISSN-L)
- 1708-0428
- OpenAlex
- W2755711258
- Cited by
- 108
- References
- 36
- Citations by year
- 2026: 5 · 2025: 8 · 2024: 3 · 2023: 16 · 2022: 18 · 2021: 20 · 2020: 19 · 2019: 10 · 2018: 7
- FWCI
- 2.09
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Obesity Surgery (publishedVersion)
- PubMed (publishedVersion)
- University of Thessaly Institutional Repository (University of Thessaly) (submittedVersion)
- Topics
- Health Sciences › Medicine › Surgery › Bariatric Surgery and Outcomes
- Health Sciences › Medicine › Gastroenterology › Gallbladder and Bile Duct Disorders
- Health Sciences › Medicine › Gastroenterology › Biliary and Gastrointestinal Fistulas
- Keywords
- ursodeoxycholic acid, gallstone prevention
- MeSH terms
- Adult, Cholecystectomy, Humans, Obesity, Morbid, Ursodeoxycholic Acid, Chemoprevention, Gallstones, Bariatric Surgery
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