The stacked over-expression of FPS, CYP71AV1 and CPR genes leads to the increase of artemisinin level in Artemisia annua L.
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Co-overexpression of CYP71AV1, CPR and FPS resulted in 3.6-fold higher artemisinin in the transgenic line.
“The cooverexpression of CYP71AV1 , CPR and FPS resulted in 3.6fold higher artemisinin in the transgenic line (Chen et al. 2012).”
From Enhancing artemisinin content in and delivery from Artemisia annua: a review of alternative, classical, and transgenic approaches (2021) · cites this paper as Chen et al. 2012
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- Authors
- Chen, Y., Shen, Q., Wang, Y., Wang, T., Wu, S., Zhang, L., Lu, X., Zhang, F., Jiang, W., Qiu, B., Gao, E., Sun, X., & Tang, K.
- Affiliations
- Shanghai Jiao Tong University (CN)
- Corresponding author
- Tang, Kexuan
- ORCID
- Venue
- Plant Biotechnology Reports
- Published
- 2012-10-04
- Volume
- 7
- Issue
- 3
- Pages
- 287-295
- ISSN
- 1863-5466 (ISSN-L)
- 1863-5474
- OpenAlex
- W2077381490
- Cited by
- 38
- References
- 47
- Citations by year
- 2026: 3 · 2025: 2 · 2024: 3 · 2023: 5 · 2022: 4 · 2021: 2 · 2020: 1 · 2019: 1 · 2018: 2 · 2017: 3 · 2016: 5 · 2015: 3 · 2014: 3 · 2013: 1
- FWCI
- 0.84
- Type
- journal article
- Language
- en
- Open access
- closed
- Licence
- www.springer.com/tdm (tdm)
- Locations
- Plant Biotechnology Reports (publishedVersion)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Plant biochemistry and biosynthesis
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Plant tissue culture and regeneration
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Cancer Research › Sesquiterpenes and Asteraceae Studies
- Keywords
- artemisinin, Artemisia annua, farnesyl diphosphate synthase, CYP71AV1, NADPH-cytochrome P450 reductase, artemisinin biosynthesis, transgenic plants, Agrobacterium-mediated transformation, sesquiterpene lactones
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