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Skin Barrier Defects in Atopic Dermatitis
Open accessAbstract
Atopic dermatitis (AD) is a chronic inflammatory skin condition with complex etiology that is dependent upon interactions between the host and the environment. Acute skin lesions exhibit the features of a Th2-driven inflammatory disorder, and many patients are highly atopic. The skin barrier plays key roles in immune surveillance and homeostasis, and in preventing penetration of microbial products and allergens. Defects that compromise the structural integrity or else the immune function of the skin barrier play a pivotal role in the pathogenesis of AD. This article provides an overview of the array of molecular building blocks that are essential to maintaining healthy skin. The basis for structural defects in the skin is discussed in relation to AD, with an emphasis on filaggrin and its genetic underpinnings. Aspects of innate immunity, including the role of antimicrobial peptides and proteases, are also discussed.
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“One of the main genetic factors associated with AD is the mutation in the FLG gene, which produces function impairment leading to a compromised skin barrier.”
From Update on the pathogenesis of atopic dermatitis. (2024) · cites this paper as [49]
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Cites
Palmer, C. N. A., Irvine, A. D., Terron-Kwiatkowski, A., Zhao, Y., Liao, H., Lee, S. P., Goudie, D. R., Sandilands, A., Campbell, L. E., Smith, F. J. D., et al. (2006) · Nature Genetics · doi:10.1038/ng1767 · Cited by 2,978
Human epithelial cells trigger dendritic cell–mediated allergic inflammation by producing TSLP
Soumelis, V., Reche, P. A., Kanzler, H., Yuan, W., Edward, G., Homey, B., Gilliet, M. F., Ho, S., Antonenko, S. V., Lauerma, A., et al. (2002) · Nature Immunology · doi:10.1038/ni805 · Cited by 2,221
Endogenous Antimicrobial Peptides and Skin Infections in Atopic Dermatitis
Ong, P. Y., Ohtake, T., Brandt, C., Strickland, I., Boguniewicz, M., Ganz, T., Gallo, R. L., & Leung, D. Y. M. (2002) · New England Journal of Medicine · doi:10.1056/nejmoa021481 · Cited by 1,960
Filaggrin Mutations Associated with Skin and Allergic Diseases
Irvine, A. D., McLean, W. H. I., & Leung, D. Y. M. (2011) · New England Journal of Medicine · doi:10.1056/nejmra1011040 · Cited by 1,217
Cytokine modulation of atopic dermatitis filaggrin skin expression
Howell, M. D., Kim, B. E., Gao, P., Grant, A. V., Boguniewicz, M., DeBenedetto, A., Schneider, L., Beck, L. A., Barnes, K. C., & Leung, D. Y. M. (2007) · Journal of Allergy and Clinical Immunology · doi:10.1016/j.jaci.2007.04.031 · Cited by 1,084
Imokawa, G., Abe, A., Jin, K., Higaki, Y., Kawashima, M., & Hidano, A. (1991) · Journal of Investigative Dermatology · doi:10.1111/1523-1747.ep12470233 · Cited by 1,040
Loss-of-function mutations in the gene encoding filaggrin cause ichthyosis vulgaris
Smith, F. J. D., Irvine, A. D., Terron-Kwiatkowski, A., Sandilands, A., Campbell, L., Zhao, Y., Liao, H., Evans, A. T., Goudie, D. R., Lewis‐Jones, S., et al. (2006) · Nature Genetics · doi:10.1038/ng1743 · Cited by 1,026
Mutations in SPINK5, encoding a serine protease inhibitor, cause Netherton syndrome
Chavanas, S., Bodemer, C., Rochat, A., Hamel‐Teillac, D., Ali, M., Irvine, A. D., Bonafé, J., WILKINSON, J. D., Taı̈eb, A., Barrandon, Y., et al. (2000) · Nature Genetics · doi:10.1038/75977 · Cited by 851
γ-Secretase-mediated proteolysis in cell-surface-receptor signalling
Fortini, M. (2002) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm910 · Cited by 827
Der p 1 facilitates transepithelial allergen delivery by disruption of tight junctions
Wan, H., Winton, H. L., Soeller, C., Tovey, E. R., Gruenert, D. C., Thompson, P. J., Stewart, G. A., Taylor, G. W., Garrod, D. R., Cannell, M. B., et al. (1999) · Journal of Clinical Investigation · doi:10.1172/jci5844 · Cited by 775
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Franco, J., Rajwa, B. P., Ferreira, C. R., Sundberg, J. P., & HogenEsch, H. (2020) · Metabolites · doi:10.3390/metabo10070299 · Cited by 12
Is miRNA Regulation the Key to Controlling Non-Melanoma Skin Cancer Evolution?
Tamaș, T., Băciuț, M. F., Nutu, A. M., Bran, S., Armencea, G., Stoia, S., Manea, A., Crişan, L., Opriș, H., Onisor, F. G., et al. (2021) · Genes · doi:10.3390/genes12121929 · Cited by 12
Park, S. H., Jang, S., & Kim, H. K. (2021) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2021.112344 · Cited by 11
Wang, L., Wang, B., Kou, E., Du, L., & Zhu, Y. (2023) · Frontiers in Immunology · doi:10.3389/fimmu.2023.1259515 · Cited by 11
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Lee, M. F. J., Hammouda, M. B., Miao, W., Okafor, A. E., Jin, Y. J., Sun, H., Jain, V., Markovtsov, V. V., Diao, Y., Gregory, S. G., et al. (2024) · Journal of Investigative Dermatology · doi:10.1016/j.jid.2024.04.017 · Cited by 11
Ribet, V., Gurdak, M., Ferret, P., Brinio, E., Giordano‐Labadie, F., & Rossi, A. B. (2019) · Journal of the European Academy of Dermatology and Venereology · doi:10.1111/jdv.15785 · Cited by 19
Lander, J. M., Supp, D. M., He, H., Martin, L. J., Chen, X., Weirauch, M. T., Boyce, S. T., & Kopan, R. (2017) · PLoS ONE · doi:10.1371/journal.pone.0184500 · Cited by 11
Campbell, A.-C., Baik, J. E., Sarker, A., Brown, S., Park, H. J., Kuonqui, K. G., Shin, J., Pollack, B. L., Roberts, A., Ashokan, G., et al. (2024) · Journal of Investigative Dermatology · doi:10.1016/j.jid.2024.05.017 · Cited by 12
The frequency of polymorphic variants of filaggrin gene and clinical atopic dermatitis
Filipowska-Grońska, A., Weryńska-Kalemba, M., Bożek, A., Filipowska, B., Żebracka‐Gala, J., Rusinek, D., Kula, D., & Jarząb, J. (2016) · Advances in Dermatology and Allergology · doi:10.5114/pdia.2015.48036 · Cited by 10
LILRA6 copy number variation correlates with susceptibility to atopic dermatitis
López-Álvarez, M. R., Jiang, W., Jones, D. C., Jayaraman, J., Johnson, C., Cookson, W., Moffatt, M. F., Trowsdale, J., & Traherne, J. A. (2016) · Immunogenetics · doi:10.1007/s00251-016-0924-z · Cited by 10
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Hon, K. E., Loo, S. K. F., Leung, A. K. C., Li, J. T. S., & Lee, V. W. Y. (2020) · Expert Opinion on Drug Discovery · doi:10.1080/17460441.2020.1722639 · Cited by 9
Lisante, T. A., Kizoulis, M. G., Nuñez, C., & Hartman, C. L. (2023) · Journal of Dermatological Treatment · doi:10.1080/09546634.2023.2241587 · Cited by 10
Yoo, S., Kim, J., Jeong, E. T., Hwang, S. J., Kang, N., & Lee, J. (2024) · Skin Research and Technology · doi:10.1111/srt.13655 · Cited by 9
Experimental Drugs with the Potential to Treat Atopic Eczema
Hon, K. E., Chan, V. P. Y., & Leung, A. K. C. (2021) · Journal of Experimental Pharmacology · doi:10.2147/jep.s259299 · Cited by 10
Neil, J. E., Lenn, J. D., Brown, M. B., & Williams, A. C. (2022) · International Journal of Pharmaceutics · doi:10.1016/j.ijpharm.2022.121610 · Cited by 9
Kim, T., Park, N.-J., Jo, B.-G., Paik, J., Choi, S., Kim, S., & Yang, M. H. (2022) · Antioxidants · doi:10.3390/antiox11071344 · Cited by 9
Hwang, Y., Song, H., Lee, A., Ha, H., & Kim, T. S. (2020) · Nutrients · doi:10.3390/nu12113238 · Cited by 9
Eom, J.-E., Shin, D., Kim, G.-D., Yoon, J., Shin, H. S., & Lee, S. Y. (2024) · Food & Function · doi:10.1039/d4fo00933a · Cited by 8
Subclinical inflammation precedes atopic dermatitis relapses
Al, B., Holzscheck, N., Traidl, S., Freimooser, S., Roesner, L. M., Mießner, H., Dittrich‐Breiholz, O., Reuter, H., Werfel, T., & Seidel, J. A. (2025) · Journal of Allergy and Clinical Immunology · doi:10.1016/j.jaci.2025.03.033 · Cited by 9
Effect of scratching and friction on human skin in vivo
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Huang, Y., Zhou, W., Liu, S., Zeng, D., & Zhou, W. (2024) · Gene · doi:10.1016/j.gene.2024.148397 · Cited by 8
Chen, G. F., Hwang, E., Leonard, C. E., & Cohen, J. M. (2024) · PLoS ONE · doi:10.1371/journal.pone.0310498 · Cited by 8
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Eberting, C. L. D. (2014) · Journal of Allergy & Therapy · doi:10.4172/2155-6121.1000187 · Cited by 8
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Li, Y., Zheng, H., Yin, L., Li, W., Guo, X., & Lv, Z. (2020) · Medicine · doi:10.1097/md.0000000000020329 · Cited by 6
Lin, L.-W., Denison, M. S., & Rice, R. H. (2021) · Toxicological Sciences · doi:10.1093/toxsci/kfab071 · Cited by 6
Wu, Q., Jia, T., Gu, H., Guo, R., Kaku, K., & Wu, W. (2019) · Annals of Dermatology · doi:10.5021/ad.2019.31.6.611 · Cited by 5
Kucharska, M., Kwiliński, K., Wawrzyńska, B., Cąkała, M., Kruszewski, A., Paduszyńska, N., Dąbrowska, A., Przybysz, P., & Szyszka, M. (2024) · Quality in Sport · doi:10.12775/qs.2024.19.54073 · Cited by 4
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Calama, E., Blanco, A. I., Trincado, J. L., Nueda, A., Gil, F., Aniorte, G., Godessart, N., & Gavaldà, A. (2024) · Experimental Dermatology · doi:10.1111/exd.70024 · Cited by 4
Dębińska, A., Danielewicz, H., Boznański, A., Matusiak, Ł., & Szepietowski, J. C. (2022) · Advances in Dermatology and Allergology · doi:10.5114/ada.2022.113145 · Cited by 4
Rezaei, A., Ganashalingam, Y., Schindler, S., Spengler, B., Keck, C. M., & Schulz, S. (2024) · Rapid Communications in Mass Spectrometry · doi:10.1002/rcm.9891 · Cited by 4
Lee, J. O., Jang, Y., Park, A. Y., Lee, J. M., Jeong, K., Jeon, S.-H., Jin, H. Z., Im, M., Kim, J.-W., & Kim, B. J. (2024) · Journal of Microbiology and Biotechnology · doi:10.4014/jmb.2406.06045 · Cited by 5
Nakanishi, S., Hasegawa, T., Maeno, K., Motoyama, A., & Denda, M. (2024) · iScience · doi:10.1016/j.isci.2024.111093 · Cited by 4
Liu, X., Hage, T., Chen, L.-C., Wang, E. H. C., Liao, I., Goldberg, J., Gosto, S., Cziryak, P., Senna, M. M., Chen, Y., et al. (2024) · Journal of Cosmetic Dermatology · doi:10.1111/jocd.16662 · Cited by 5
Sun, Y., Li, X., Deng, N.-N., Zhao, T., Lv, J., & Chu, J. (2025) · Archives of Dermatological Research · doi:10.1007/s00403-025-04168-0 · Cited by 4
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Kim, J., Hong, J.-E., Woo, S.-H., Rhee, K., Kim, Y. S., & Lee, Y. (2024) · Applied Sciences · doi:10.3390/app14146346 · Cited by 3
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Fornal, R., Książkiewicz, A., Fornal, A., & Zarzycka, D. (2022) · Postępy Higieny i Medycyny Doświadczalnej · doi:10.2478/ahem-2022-0033 · Cited by 3
Yuindartanto, A., Sawitri, S., Astindari, Prakoeswa, C. R. S., Damayanti, D., Anggraen, S., Umborowati, M. A., Zulkarnain, I., Listiawan, M. Y., & Hidayati, A. N. (2023) · Berkala Ilmu Kesehatan Kulit dan Kelamin · doi:10.20473/bikk.v35.1.2023.27-39 · Cited by 3
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Kim, J., Lee, J. M., Park, S. J., Nam, Y. R., Choi, S. W., Nam, J., Kim, H. J., & Kim, W. K. (2024) · International Journal of Molecular Sciences · doi:10.3390/ijms25168894 · Cited by 2
Shook, M., Lu, X., Chen, X., Edsall, L., Granitto, M., Virolainen, S. J., Forney, C. R., Donmez, O. A., Parameswaran, S., Fadden, C., et al. (2025) · Journal of Allergy and Clinical Immunology · doi:10.1016/j.jaci.2025.07.032 · Cited by 2
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Wölbing, F., Köberle, M., Volz, T., & Biedermann, T. (2018) · Springer eBooks · doi:10.1007/978-3-319-90545-7_12 · Cited by 2
Wu, H., & Sivamani, R. K. (2022) · Elsevier eBooks · doi:10.1016/b978-0-323-84744-5.00005-x · Cited by 2
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Kalyuzhin, O. V. (2017) · Russian Journal of Allergy · doi:10.36691/rja302 · Cited by 2
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Smith, P., Koval, M. H., & Levy, J. M. (2020) · Current Otorhinolaryngology Reports · doi:10.1007/s40136-020-00267-w · Cited by 2
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Yu, T., & Yuan, Y. (2024) · Preprints.org · doi:10.20944/preprints202408.0989.v1 · Cited by 2
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fm, M., & alajmi, F. (2018) · International Journal of Advanced Research · doi:10.21474/ijar01/6786 · Cited by 1
Huang, F., Zhu, X., & Liang, X. (2025) · Frontiers in Medicine · doi:10.3389/fmed.2025.1539386 · Cited by 1
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Truchuelo, M. T., Reyes, E., Jaén, P., Delgado, A., & Vitale, M. (2015) · Piel · doi:10.1016/j.piel.2015.04.011 · Cited by 1
Atopic dermatitis and filaggrin: restoring barriers to control the disease
Cardili, R. N., Melo, J. M. L., Roselino, A. M. F., Moreno, A. S., Castro, A. P. M., & Arruda, L. K. (2013) · Brazilian Journal of Allergy and Immunology (BJAI) · doi:10.5935/2318-5015.20130033 · Cited by 1
Crespo, C. (2017) · Pharmacy & Pharmacology International Journal · doi:10.15406/ppij.2017.05.00143 · Cited by 1
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Zhang, R., Bi, R., Rajarahm, P., Dinish, U. S., & Olivo, M. (2022) · doi:10.1117/12.2607863 · Cited by 1
Mäenpää, K., Ilves, M., Zhao, L., Alenius, H. T., Sinkko, H., & Karisola, P. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms242115629 · Cited by 1
Su, J. C., & Lowe, A. (2019) · Indian Journal of Paediatric Dermatology · doi:10.4103/ijpd.ijpd_10_19 · Cited by 1
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Niyonsaba, F., Takahashi, M., & Ikutama, R. (2020) · Juntendō Igaku/Juntendo igaku · doi:10.14789/jmj.2020.66.jmj20-r07 · Cited by 1
Hwang, S. (2021) · Clinical Dermatology Open Access Journal · doi:10.23880/cdoaj-16000236 · Cited by 1
Love, P. B. (2017) · Springer eBooks · doi:10.1007/978-3-319-53961-4_10 · Cited by 1
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Garg, N., Dhankhar, S., Chauhan, S., & Beniwal, S. (2025) · Wiley eBooks · doi:10.1002/9781394287345.ch4 · Cited by 1
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Crizón-Díaz, D. P., & Correa, V. E. F. (2018) · Piel · doi:10.1016/j.piel.2018.03.004
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Prigent, Y., & Kote, F. V. (1969) · OSTI OAI (U.S. Department of Energy Office of Scientific and Technical Information)
Michelle, V. Y., Ornelas, J. N., & Awasthi, S. (2022) · Elsevier eBooks · doi:10.1016/b978-0-323-84744-5.00022-x
Hamzawi, N. K. A. (2017) · International Journal of Advanced Research · doi:10.21474/ijar01/5939
de Barros, A. B. (2022) · Digital Library of Theses and Dissertations (Universidade de São Paulo) · doi:10.11606/d.9.2022.tde-27102022-170305 · Cited by 1
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Шабалов, А. М., Иванова, Н. А., Ilicheva, A. V., Kuzmina, G. A., & Валерьевна, Д. В. (2024) · Russian Journal of Clinical Dermatology and Venereology · doi:10.17116/klinderma202423041429
Khamidova, F. M., Нарзикулов, Р., & Толипов, М. (2025) · Международный журнал научной педиатрии · doi:10.56121/2181-2926-2025-4-2-921-927
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Metadata
- Authors
- Agrawal, R., & Woodfolk, J. A.
- Affiliations
- University of Virginia Health System (US)
- Corresponding author
- Woodfolk, Judith A.
- ORCID
- Woodfolk, Judith A.
- Venue
- Current Allergy and Asthma Reports
- Published
- 2014-03-16
- Volume
- 14
- Issue
- 5
- Pages
- 433-433
- ISSN
- 1529-7322 (ISSN-L)
- 1534-6315
- PMC
- PMC4034059
- OpenAlex
- W2070316318
- Cited by
- 201
- References
- 119
- Citations by year
- 2026: 7 · 2025: 17 · 2024: 29 · 2023: 13 · 2022: 18 · 2021: 31 · 2020: 22 · 2019: 14 · 2018: 15 · 2017: 16 · 2016: 6 · 2015: 8 · 2014: 3
- FWCI
- 12.06
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Licence
- Locations
- Current Allergy and Asthma Reports (publishedVersion)
- PubMed (publishedVersion)
- PubMed Central (acceptedVersion)
- Funders
- National Institute of Allergy and Infectious Diseases (R01AI052196)
- National Institute of Arthritis and Musculoskeletal and Skin Diseases (R01AR059058)
- Topics
- Health Sciences › Medicine › Dermatology › Dermatology and Skin Diseases
- Health Sciences › Medicine › Dermatology › Contact Dermatitis and Allergies
- Life Sciences › Pharmacology, Toxicology and Pharmaceutics › Pharmaceutical Science › Advancements in Transdermal Drug Delivery
- Keywords
- atopic dermatitis, skin barrier, filaggrin, type 2 inflammation, innate immunity, antimicrobial peptides, proteolytic enzymes, skin barrier dysfunction, atopy, host-environment interactions
- MeSH terms
- Filaggrin Proteins, Animals, Dermatitis, Atopic, Humans, Lipid Bilayers, Peptide Hydrolases, Protease Inhibitors, Skin, Tight Junctions
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