Cited by 112Adipokines, Inflammation, and Metabolic DiseasesExercise and Physiological ResponsesAdipose Tissue and Metabolism

The DOI matches its Crossref record; 49 of the 50 references it cites were found in a registry or an index.

Effects of exercise on adipokines and the metabolic syndrome

You, Tongjian, Nicklas, Barbara J.·2008·Current Diabetes Reports

DOI 10.1007/s11892-008-0003-4

Open this paper in CoChat — free account

Abstract

Adipokines, or adipose tissue-derived cytokines/proteins, may be important factors linking excess adipose tissue to individual metabolic risk factors, and the overall metabolic syndrome. Current evidence supports that aerobic exercise, alone or combined with hypocaloric diet, improves symptoms of the metabolic syndrome, possibly by altering systemic levels of inflammatory adipokines. A number of studies show that increased physical activity leads to lower circulating levels of proinflammatory cytokines and higher levels of adiponectin. However, limited data show that exercise training does not influence adipose tissue adipokine expression or release. Conversely, exercise training may influence cytokine production by circulating mononuclear cells, another important source of elevated inflammation. Future studies are needed to investigate the cellular mechanisms by which exercise training affects inflammation and whether alterations in inflammation are one mechanism by which exercise improves components of the metabolic syndrome in at-risk individuals.

Integrity signals

Registry

Crossref · 10.1007/s11892-008-0003-4

Cites

49 of 49 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

This paper’s full text isn’t openly available, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Summary of the second report of the National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel II)
Grundy, S. M., Bilheimer, D. W., Chait, A., Clark, L. T., Denke, M. A., Havel, R. J., Hazzard, W. R., Hulley, S. B., Hunninghake, D. B., Kreisberg, R. A., et al. (1993) · JAMA · doi:10.1001/jama.269.23.3015 · Cited by 27,944
Executive Summary of the Third Report of the National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III)
Expert Panel on Detection, E. (2001) · JAMA: The Journal of the American Medical Association · doi:10.1001/jama.285.19.2486 · Cited by 26,011
Obesity is associated with macrophage accumulation in adipose tissue
Weisberg, S. P., McCann, D., Desai, M., Rosenbaum, M., Leibel, R. L., & Ferrante, A. W. (2003) · Journal of Clinical Investigation · doi:10.1172/jci200319246 · Cited by 10,041
Acute-Phase Proteins and Other Systemic Responses to Inflammation
Gabay, C., & Kushner, I. (1999) · New England Journal of Medicine · doi:10.1056/nejm199902113400607 · Cited by 6,734
Adipose Tissue as an Endocrine Organ
Kershaw, E. E., & Flier, J. S. (2004) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2004-0395 · Cited by 5,522
Increased adipose tissue expression of tumor necrosis factor-alpha in human obesity and insulin resistance.
Hotamisligil, G. S., Arner, P., Caro, J. F., Atkinson, R. L., & Spiegelman, B. M. (1995) · Journal of Clinical Investigation · doi:10.1172/jci117936 · Cited by 3,543
The anti-inflammatory effect of exercise
Petersen, A. M. W., & Pedersen, B. K. (2005) · Journal of Applied Physiology · doi:10.1152/japplphysiol.00164.2004 · Cited by 3,100 · cited 1×
“The mechanism through which exercise modifies mononuclear cell production of adipokines is unknown, but could be that acute exercise results in release of “myokines” (muscle-derived cytokines; eg, IL-6) [ 47 ], and when performed regularly, adaptations in the immune system cause lower cytokine release from mononuclear…”
Background
C-Reactive Protein, the Metabolic Syndrome, and Risk of Incident Cardiovascular Events: An 8-Year Follow-Up of 14 719 Initially Healthy American Women
Ridker, P. M., Buring, J. E., Cook, N. R., & Rifai, N. (2003) · Circulation · doi:10.1161/01.cir.0000055014.62083.05 · Cited by 2,292
The Metabolic Syndrome: Prevalence and Associated Risk Factor Findings in the US Population From the Third National Health and Nutrition Examination Survey, 1988-1994
Park, Y.-W., Zhu, S., Palaniappan, L., Heshka, S., Carnethon, M. R., & Heymsfield, S. B. (2003) · Archives of Internal Medicine · doi:10.1001/archinte.163.4.427 · Cited by 2,074
Effect of Weight Loss and Lifestyle Changes on Vascular Inflammatory Markers in Obese Women: A Randomized Trial
Esposito, K., Pontillo, A., Di Palo, C., Giugliano, G., Masella, M., Marfella, R., & Giugliano, D. (2003) · JAMA · doi:10.1001/jama.289.14.1799 · Cited by 1,511

Show all 50 references

Sorted by citations

Understanding the somatic consequences of depression: biological mechanisms and the role of depression symptom profile
Penninx, B. W., Milaneschi, Y., Lamers, F., & Vogelzangs, N. (2013) · BMC Medicine · doi:10.1186/1741-7015-11-129 · Cited by 839
Physical Activity and Survival After Prostate Cancer Diagnosis in the Health Professionals Follow-Up Study
Kenfield, S. A., Stampfer, M. J., Giovannucci, E., & Chan, J. M. (2011) · Journal of Clinical Oncology · doi:10.1200/jco.2010.31.5226 · Cited by 601
Muscle as a secretory organ
Pedersen, B. K. (2013) · Comprehensive physiology · doi:10.1002/cphy.c120033 · Cited by 516
Understanding the Cellular and Molecular Mechanisms of Physical Activity-Induced Health Benefits
Neufer, P. D., Bamman, M. M., Muoio, D. M., Bouchard, C., Cooper, D. M., Goodpaster, B. H., Booth, F. W., Kohrt, W. M., Gerszten, R. E., Mattson, M. P., et al. (2015) · Cell Metabolism · doi:10.1016/j.cmet.2015.05.011 · Cited by 485
Anxiety disorders and inflammation in a large adult cohort
Vogelzangs, N., Beekman, A. T. F., de Jonge, P., & Penninx, B. W. J. H. (2013) · Translational Psychiatry · doi:10.1038/tp.2013.27 · Cited by 458
The Effect of Exercise on Visceral Adipose Tissue in Overweight Adults: A Systematic Review and Meta-Analysis
Vissers, D., Hens, W., Taeymans, J., Baeyens, J.-P., Poortmans, J., & Van Gaal, L. (2013) · PLoS ONE · doi:10.1371/journal.pone.0056415 · Cited by 331
Association of depressive disorders, depression characteristics and antidepressant medication with inflammation
Vogelzangs, N., Duivis, H. E., Beekman, A. T. F., Kluft, C., Neuteboom, J., Hoogendijk, W., Smit, J. H., de Jonge, P., & Penninx, B. W. J. H. (2012) · Translational Psychiatry · doi:10.1038/tp.2012.8 · Cited by 323
“Furthermore, behavioral interventions, such as exercise, have been shown to normalize immune and metabolic dysregulation, 53 as well as to improve depressive symptoms to some degree, 54 and might therefore be an indicated treatment for a immune/metabolic depression subgroup.”
Background
Effects of Exercise Training on Chronic Inflammation in Obesity
You, T., Arsenis, N. C., DiSanzo, B., & LaMonte, M. J. (2013) · Sports Medicine · doi:10.1007/s40279-013-0023-3 · Cited by 303
Self-citation
Induction of osteoarthritis and metabolic inflammation by a very high‐fat diet in mice: Effects of short‐term exercise
Griffin, T. M., Huebner, J. L., Kraus, V. B., Yan, Z., & Guilak, F. (2011) · Arthritis & Rheumatism · doi:10.1002/art.33332 · Cited by 243
Oxidative Stress as Pathogenesis of Cardiovascular Risk Associated with Metabolic Syndrome
Otani, H. (2010) · Antioxidants and Redox Signaling · doi:10.1089/ars.2010.3739 · Cited by 185
Fitness Versus Fatness: Moving Beyond Weight Loss in Nonalcoholic Fatty Liver Disease
Johnson, N. A., & George, J. (2010) · Hepatology · doi:10.1002/hep.23711 · Cited by 146
Inflammatory and Metabolic Dysregulation and the 2-Year Course of Depressive Disorders in Antidepressant Users
Vogelzangs, N., Beekman, A. T., van Reedt Dortland, A. K., Schoevers, R. A., Giltay, E. J., de Jonge, P., & Penninx, B. W. (2014) · Neuropsychopharmacology · doi:10.1038/npp.2014.9 · Cited by 133
Plasma adipokine and inflammatory marker concentrations are altered in obese, as opposed to non-obese, type 2 diabetes patients
Hansen, D., Dendale, P., Beelen, M., Jonkers, R. A. M., Mullens, A., Corluy, L., MEEUSEN, R. R., & van Loon, L. J. C. (2010) · European Journal of Applied Physiology · doi:10.1007/s00421-010-1362-5 · Cited by 138
Antidepressants or running therapy: comparing effects on mental and physical health in patients with depression and anxiety disorders
Verhoeven, J. E., Han, L. K. M., Lever-van Milligen, B. A., Hu, M. X., Révész, D., Hoogendoorn, A. W., Batelaan, N. M., van Schaik, D. J. F., van Balkom, A. J. L. M., van Oppen, P., et al. (2023) · Journal of Affective Disorders · doi:10.1016/j.jad.2023.02.064 · Cited by 112
Effects of aerobic training on serum omentin-1 and cardiometabolic risk factors in overweight and obese men
Saremi, A., Asghari, M., & Ghorbani, A. (2010) · Journal of Sports Sciences · doi:10.1080/02640414.2010.484070 · Cited by 103
Children With Metabolically Healthy Obesity: A Review
Vuković, R., Santos, T. J. D., Ybarra, M., & Atar, M. (2019) · Frontiers in Endocrinology · doi:10.3389/fendo.2019.00865 · Cited by 102
Subcutaneous Rather than Visceral Adipose Tissue Is Associated with Adiponectin Levels and Insulin Resistance in Young Men
Frederiksen, L., Nielsen, T. L., Wraae, K., Hagen, C., Frystyk, J., Flyvbjerg, A., Brixen, K., & Andersen, M. (2009) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2009-0980 · Cited by 96
The Intensive Diet and Exercise for Arthritis (IDEA) trial: design and rationale
Messier, S. P., Legault, C., Mihalko, S. L., Miller, G. D., Loeser, R. F., DeVita, P., Lyles, M. F., Eckstein, F., Hunter, D. J., Williamson, J. D., et al. (2009) · BMC Musculoskeletal Disorders · doi:10.1186/1471-2474-10-93 · Cited by 96
Self-citation
A new perspective of the hippocampus in the origin of exercise–brain interactions
Rendeiro, C., & Rhodes, J. S. (2018) · Brain Structure and Function · doi:10.1007/s00429-018-1665-6 · Cited by 78
Very low-calorie ketogenic diet (VLCKD) in patients with psoriasis and obesity: an update for dermatologists and nutritionists
Barrea, L., Megna, M., Cacciapuoti, S., Frías-Toral, E., Fabbrocini, G., Savastano, S., Colao, A., & Muscogiuri, G. (2020) · Critical Reviews in Food Science and Nutrition · doi:10.1080/10408398.2020.1818053 · Cited by 75
The Association Between Physical Activity and the Risk of Incident Psoriasis
Tsibris, H. C., Han, J., Li, T., & Qureshi, A. A. (2012) · Archives of Dermatology · doi:10.1001/archdermatol.2012.943 · Cited by 77
Evidence of the influence of physical activity on the metabolic syndrome and/or on insulin resistance in pediatric populations: a systematic review
Guinhouya, B. C., Samouda, H., Zitouni, D., Vilhelm, C., & Hubert, H. (2011) · International Journal of Pediatric Obesity · doi:10.3109/17477166.2011.605896 · Cited by 78
Vitamin D increases PPARγ expression and promotes beneficial effects of physical activity in metabolic syndrome
Hoseini, R., Damirchi, A., & Babaei, P. (2016) · Nutrition · doi:10.1016/j.nut.2016.06.010 · Cited by 72
Adiponectin and Smoking Status: A Systematic Review
Kotani, K., Hazama, A., Hagimoto, A., Saika, K., Shigeta, M., Katanoda, K., & Nakamura, M. (2012) · Journal of Atherosclerosis and Thrombosis · doi:10.5551/jat.11833 · Cited by 66
Development and Application of a Lifestyle Score for Prevention of Lethal Prostate Cancer
Kenfield, S. A., Batista, J. L., Jahn, J. L., Downer, M. K., Blarigan, E. L. V., Sesso, H. D., Giovannucci, E. L., Stampfer, M. J., & Chan, J. M. (2015) · JNCI Journal of the National Cancer Institute · doi:10.1093/jnci/djv329 · Cited by 66
Metabolic dysregulation and late-life depression: a prospective study
Marijnissen, R. M., Vogelzangs, N., Mulder, M., van den Brink, R. H. S., Comijs, H. C., & Voshaar, R. C. O. (2016) · Psychological Medicine · doi:10.1017/s0033291716003196 · Cited by 64
Adipocytokines and the metabolic syndrome among older persons with and without obesity: the InCHIANTI study
Stenholm, S., Koster, A., Alley, D. E., Visser, M., Maggio, M. G., Harris, T. B., Egan, J. M., Bandinelli, S., Guralnik, J. M., & Ferrucci, L. (2009) · Clinical Endocrinology · doi:10.1111/j.1365-2265.2009.03742.x · Cited by 65
The Effect of Exercise on Obesity, Body Fat Distribution and Risk for Type 2 Diabetes
Goedecke, J. H., & Micklesfield, L. K. (2014) · Medicine and sport science/Medicine and sport · doi:10.1159/000357338 · Cited by 63
The effect of a 12 week walking intervention on markers of insulin resistance and systemic inflammation
Gray, S. R., Baker, G., Wright, A., Fitzsimons, C. F., Mutrie, N., & Nimmo, M. A. (2008) · Preventive Medicine · doi:10.1016/j.ypmed.2008.10.013 · Cited by 58
Epicardial fat gene expression after aerobic exercise training in pigs with coronary atherosclerosis: relationship to visceral and subcutaneous fat
Booth, F. W., Laughlin, M. H., Arce‐Esquivel, A. A., Sacks, H. S., Bahouth, S. W., & Fain, J. N. (2010) · Journal of Applied Physiology · doi:10.1152/japplphysiol.00621.2010 · Cited by 57
Calorie restriction and endurance exercise share potent anti-inflammatory function in adipose tissues in ameliorating diet-induced obesity and insulin resistance in mice
Huang, P., Li, S., Shao, M., Qi, Q., Zhao, F., You, J., Mao, T., Li, W., Yan, Z., & Liu, Y. (2010) · Nutrition & Metabolism · doi:10.1186/1743-7075-7-59 · Cited by 56
Exercise improves adiposopathy, insulin sensitivity and metabolic syndrome severity independent of intensity
Heiston, E. M., Eichner, N. Z. M., Gilbertson, N. M., & Malin, S. K. (2020) · Experimental Physiology · doi:10.1113/ep088158 · Cited by 58
Twelve-Week Aerobic Training Decreases Chemerin Level and Improves Cardiometabolic Risk Factors in Overweight and Obese Men
Saremi, A., Shavandi, N., Parastesh, M., & Daneshmand, H. (2010) · Asian Journal of Sports Medicine · doi:10.5812/asjsm.34860 · Cited by 54
Advantages of exercise in rehabilitation, treatment and prevention of altered morphological features in knee osteoarthritis. A narrative review.
Musumeci, G., Loreto, C., Imbesi, R., Trovato, F. M., Giunta, A. D., Lombardo, C., Castorina, S., & Castrogiovanni, P. (2014) · PubMed · doi:10.14670/hh-29.707 · Cited by 53
The impact of depression and anxiety treatment on biological aging and metabolic stress: study protocol of the Mood treatment with antidepressants or running (MOTAR) study
Milligen, B. A. L.-V., Verhoeven, J. E., Schmaal, L., van Velzen, L. S., Révész, D., Black, C. N., Han, L. K. M., Horsfall, M., Batelaan, N. M., van Balkom, A. J. L. M., et al. (2019) · BMC Psychiatry · doi:10.1186/s12888-019-2404-0 · Cited by 52
Psoriasis and sport: a new ally?
Balato, N., Megna, M., Palmisano, F., Patruno, C., Napolitano, M., Scalvenzi, M., & Ayala, F. (2015) · Journal of the European Academy of Dermatology and Venereology · doi:10.1111/jdv.12607 · Cited by 48
Cellular aging in depression: Permanent imprint or reversible process?
Verhoeven, J. E., Révész, D., Wolkowitz, O. M., & Penninx, B. W. J. H. (2014) · BioEssays · doi:10.1002/bies.201400068 · Cited by 45
The Effect of Exercise on Serum Levels of Interleukin-18 and Components of the Metabolic Syndrome
Trøseid, M., Lappegård, K. T., Mollnes, T. E., Arnesen, H., & Seljeflot, I. (2009) · Metabolic Syndrome and Related Disorders · doi:10.1089/met.2009.0003 · Cited by 41
Exposure to perfluoroalkylated substances (PFAS) in relation to fitness, physical activity, and adipokine levels in childhood: The european youth heart study
Domazet, S. L., Jensen, T. K., Wedderkopp, N., Nielsen, F., Andersen, L. B., & Grøntved, A. (2020) · Environmental Research · doi:10.1016/j.envres.2020.110110 · Cited by 40
Supplementation with Spinach-Derived Thylakoid Augments the Benefits of High Intensity Training on Adipokines, Insulin Resistance and Lipid Profiles in Males with Obesity
Saeidi, A., Saei, M. A., Mohammadi, B., Zarei, H. R. A., Vafaei, M., Mohammadi, A. S., Barati, M., Montazer, M., Razi, O., Kiyumi, M. H. A., et al. (2023) · Frontiers in Endocrinology · doi:10.3389/fendo.2023.1141796 · Cited by 33
Independent and Combined Effects of Antioxidant Supplementation and Circuit Resistance Training on Selected Adipokines in Postmenopausal Women
Saeidi, A., Jabbour, G., Ahmadian, M., Daloii, A. A., Malekian, F., Hackney, A. C., Saedmocheshi, S., Basati, G., Abderrahman, A. B., & Zouhal, H. (2019) · Frontiers in Physiology · doi:10.3389/fphys.2019.00484 · Cited by 33
Update on therapeutic strategies to increase adiponectin function and secretion in metabolic syndrome
Montecucco, F., & Mach, F. (2009) · Diabetes Obesity and Metabolism · doi:10.1111/j.1463-1326.2008.00986.x · Cited by 29
The effect of increased ambulatory activity on markers of chronic low‐grade inflammation: evidence from the PREPARE programme randomized controlled trial
Yates, T. E., Davies, M. J., Gorely, T., Talbot, D. C. S., Bull, F., Sattar, N. A., & Khunti, K. K. (2010) · Diabetic Medicine · doi:10.1111/j.1464-5491.2010.03091.x · Cited by 27
The Influence of Cardiac Rehabilitation on Inflammation and Metabolic Syndrome in Women With Coronary Heart Disease
Beckie, T. M., Beckstead, J. W., & Groer, M. E. (2010) · The Journal of Cardiovascular Nursing · doi:10.1097/jcn.0b013e3181b7e500 · Cited by 27
Exercise-induced lowering of chemerin is associated with reduced cardiometabolic risk and glucose-stimulated insulin secretion in older adults
Malin, S. K., Navaneethan, S. D., Mulya, A., Huang, H., & Kirwan, J. P. (2014) · The journal of nutrition health & aging · doi:10.1007/s12603-014-0459-7 · Cited by 26
Efeitos de curto prazo de um programa de atividade física moderada em pacientes com síndrome metabólica
Colombo, C., de Macedo, R. M., Fernandes-Silva, M. M., Caporal, A. M., Stinghen, A. E. M., Costantini, C., Baena, C. P., Guarita-Souza, L. C., & Faria‐Neto, J. R. (2013) · Einstein (São Paulo) · doi:10.1590/s1679-45082013000300011 · Cited by 26
Muscle as an Endocrine Organ
Legaard, G. E., & Pedersen, B. K. (2018) · Elsevier eBooks · doi:10.1016/b978-0-12-814593-7.00013-x · Cited by 24
The potential impact of biochemical mediators on telomere attrition in major depressive disorder and implications for future study designs: A narrative review
Manoliu, A., Bosch, O. G., Brakowski, J., Brühl, A. B., & Seifritz, E. (2017) · Journal of Affective Disorders · doi:10.1016/j.jad.2017.08.022 · Cited by 25
Walking and inflammatory markers in individuals screened for type 2 diabetes
Yates, T. E., Davies, M. J., Brady, E. M., Webb, D. R., Gorely, T., Bull, F., Talbot, D. C. S., Sattar, N. A., & Khunti, K. K. (2008) · Preventive Medicine · doi:10.1016/j.ypmed.2008.06.015 · Cited by 22
The Associations between Mental Well-Being and Adherence to Physical Activity Guidelines in Patients with Cardiovascular Disease: Results from the Scottish Health Survey
Salman, A., Sellami, M., Al-Mohannadi, A. S., & Chun, S. (2019) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph16193596 · Cited by 19
Association of leisure physical activity and sleep with cardiovascular risk factors in postmenopausal women
Casas, R. S., Gabriel, K. P., Kriska, A. M., Kuller, L. H., & Conroy, M. B. (2011) · Menopause The Journal of The North American Menopause Society · doi:10.1097/gme.0b013e318230f531 · Cited by 19
Exercise plus caloric restriction lowers soluble RAGE in adults with chronic kidney disease
Malin, S. K., Navaneethan, S. D., Fealy, C. E., Scelsi, A. R., Huang, H., Rocco, M. B., & Kirwan, J. P. (2020) · Obesity Science & Practice · doi:10.1002/osp4.408 · Cited by 18
Muscle atrophy in cancer: a role for nutrition and exercise
Mourtzakis, M., & Bedbrook, M. (2009) · Applied Physiology, Nutrition, and Metabolism · doi:10.1139/h09-075 · Cited by 17
High-Intensity Interval Training Does Not Change Vaspin and Omentin and Does Not Reduce Visceral Adipose Tissue in Obese Rats
Costa, L. R., de Castro, C. A., Marine, D. A., Fabrizzi, F., Furino, V. D. O., Malavazi, I., Aníbal, F. D. F., & Duarte, A. C. G. D. O. (2021) · Frontiers in Physiology · doi:10.3389/fphys.2021.564862 · Cited by 17
Exercise reduced the formation of new adipocytes in the adipose tissue of mice in vivo
Allerton, T. D., Savoie, J. J., Fitch, M. D., Hellerstein, M. K., Stephens, J. M., & White, U. A. (2021) · PLoS ONE · doi:10.1371/journal.pone.0244804 · Cited by 16
The impact of high intensity interval training on serum chemerin, tumor necrosis factor-alpha and insulin resistance in overweight women
TaheriChadorneshin, H., Cheragh-Birjandi, S., Goodarzy, S., & Ahmadabadi, F. (2019) · Obesity Medicine · doi:10.1016/j.obmed.2019.100101 · Cited by 15
Type 2 diabetes mellitus risk and exercise: is resistin involved?
Cobbold, C. (2019) · The Journal of Sports Medicine and Physical Fitness · doi:10.23736/s0022-4707.18.08258-0 · Cited by 22
The effects of two different exercise programmes on adipose tissue hormones in sedentary middle-aged women
Özcan, O., Bostanci, M. Ö., Çiçek, G., & Yamaner, F. (2015) · Archives of Physiology and Biochemistry · doi:10.3109/13813455.2014.1003567 · Cited by 14
Aerobic Exercise Training Attenuates Obesity-Related Hypogonadism in Male Rats
You, T., DiSanzo, B., & Arsenis, N. C. (2013) · Medicine & Science in Sports & Exercise · doi:10.1249/mss.0b013e318285816c · Cited by 13
Self-citation
Highlighting the idea of exerkines in the management of cancer patients with cachexia: novel insights and a critical review
Hekmatikar, A. H. A., Nelson, A. R., & Petersen, A. C. (2023) · BMC Cancer · doi:10.1186/s12885-023-11391-3 · Cited by 13
Toll-like receptor signaling and serum levels of interferon β and lipopolysaccharide binding protein are related to abdominal obesity: a case-control study between metabolically healthy and metabolically unhealthy obese individuals
Naghizadeh, M., Baradaran, B., Saghafi‐Asl, M., Amiri, P., Shanehbandi, D., Karamzad, N., & Khosroshahi, L. M. (2018) · Nutrition Research · doi:10.1016/j.nutres.2018.03.014 · Cited by 12
Exercise Training-Enhanced Lipolytic Potency to Catecholamine Depends on the Time of the Day
Kato, H., Ogasawara, J., Takakura, H., Shirato, K., Sakurai, T., Kizaki, T., & Izawa, T. (2020) · International Journal of Molecular Sciences · doi:10.3390/ijms21186920 · Cited by 11
Association of endotoxaemia with serum free fatty acids in metabolically healthy and unhealthy abdominally obese individuals: a case–control study in northwest of Iran
Saghafi‐Asl, M., Amiri, P., Naghizadeh, M., Ghavami, S. M., & Karamzad, N. (2017) · BMJ Open · doi:10.1136/bmjopen-2017-015910 · Cited by 10
Rôle de l’activité physique dans la lutte contre le syndrome métabolique infantile
Guinhouya, B. C. (2009) · médecine/sciences · doi:10.1051/medsci/20092510827 · Cited by 11
Leptin mediate central obesity on the severity of cardiovascular autonomic neuropathy in well-controlled type 2 diabetes and prediabetes
Lai, Y., Chen, M. H., Lin, W., Chiu, W.-C., Cheng, B., Chen, J., Tsai, N., Huang, C., & Lu, C. (2020) · Journal of Translational Medicine · doi:10.1186/s12967-020-02559-7 · Cited by 10
Etude du syndrome métabolique et l'activité physique chez une population de la ville de Marrakech, au Maroc
Hannoun, Z., Harraqui, K., Ali, R. A. B., Tahiri, K., Smail, O. B., Arabi, F. E., & Bour, A. (2021) · Pan African Medical Journal · doi:10.11604/pamj.2021.38.21.20219 · Cited by 12
Depression Subtypes and Inflammation: Atypical Rather Than Melancholic Depression Is Linked With Immunometabolic Dysregulations
Lamers, F., Milaneschi, Y., & Penninx, B. W. J. H. (2018) · Elsevier eBooks · doi:10.1016/b978-0-12-811073-7.00026-x · Cited by 12
Indicators of response to exercise training: a systematic review and meta-analysis
Ardavani, A., Aziz, H., Phillips, B. E., Doleman, B., Ramzan, I., Mozaffar, B., Atherton, P. J., & IDRIS, I. R. (2021) · BMJ Open · doi:10.1136/bmjopen-2020-044676 · Cited by 9
Exercise training lowers serum chemerin concentration in obese children
Zehsaz, F., Farhangi, N., & Ghahramani, M. (2016) · Science & Sports · doi:10.1016/j.scispo.2016.07.007 · Cited by 9
COMPARISON OF AEROBIC, RESISTANCE AND CONCURRENT EXERCISE ON LIPID PROFILES AND ADIPONECTIN IN SEDENTARY MEN
Ali, A. M., & Abedi, B. (2012) · doi:10.22100/jkh.v7i1.116 · Cited by 9
The Potential of Exerkines in Women’s COVID-19: A New Idea for a Better and More Accurate Understanding of the Mechanisms behind Physical Exercise
Suzuki, K., Hekmatikar, A. H. A., Jalalian, S., Abbasi, S., Ahmadi, E., Kazemi, A., Ruhee, R. T., & Khoramipour, K. (2022) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph192315645 · Cited by 8
Aerobic steps as measured by pedometry and their relation to central obesity.
Duchečková, P., & Forejt, M. (2014) · Europe PMC (PubMed Central) · Cited by 7
THE EFFECT OF ACUTE EXERCISE ON SERUM VASPIN LEVEL AND ITS RELATION TO INSULIN SENSITIVITY IN OVERWEIGHT ELDERLY MEN
Bashiri, J., Adel, R., Farhad, G., Ahmadizad, S., Nikookheslat, S. D., & Moradi, A. (2014) · DOAJ (DOAJ: Directory of Open Access Journals) · Cited by 6
Association of Cardiopulmonary Exercise Capacity and Adipokines in the General Population
Lendeckel, F., Zylla, S., Markus, M. R. P., Ewert, R., Gläser, S., Völzke, H., Albrecht, D., Friedrich, N., Nauck, M. A., Felix, S. B., et al. (2022) · International Journal of Sports Medicine · doi:10.1055/a-1699-2380 · Cited by 6
Effect of Aquatic Extract of Ferulago angulata Boiss With Aerobic Exercises on Serum Levels of Interleukin-10 and C-Reactive Protein of Obese Males
Zakavi, I., Karimyan, A., Isazadeh, R., Bahadoram, M., Sough, A. J., & Valipour, A. A. (2018) · Cited by 5
Effects of combination training on insulin resistance index and some inflammatory markers in inactive men
Noushabadi, M. A., & Abedi, B. (2012) · Cited by 4
The Effect of a Ten-Week Aerobic Training on Atherogenic Indices, Lipid Profile, and Body Composition in Postmenopausal Women with Type II Diabetes
Ghorbanian, B., & Saberi, Y. (2017) · Journal of Obstetrics Gynecology and Cancer Research · doi:10.5812/jogcr.11958 · Cited by 4
Efecto potencial del ejercicio físico y del consumo de micronutrientes durante la gestación en factores maternos y placentarios asociados con enfermedades crónicas no transmisibles (ECNT) del adulto
Echeverri, I., Ramírez‐Vélez, R., Ortega, J. G., Mosquera, M., Mateus, J. C., & de Plata, A. C. A. (2009) · Colombia medica · doi:10.25100/cm.v40i4.677 · Cited by 6
The combined effects of Tabata training and cinnamon supplementation on metabolic changes and body composition in soldiers with overweight or obesity
Rad, R. S., Omidi, H., & Alipour, M. (2025) · Journal of the International Society of Sports Nutrition · doi:10.1080/15502783.2025.2564237 · Cited by 4
EFECTO DEL EJERCICIO FÍSICO AERÓBICO SOBRE LOS NIVELES SÉRICOS DE ADIPONECTINA Y LEPTINA EN MUJERES POSMENOPÁUSICAS
Aranzález, L. H., Mockus, I., de Peña, D. R., Mancera-Soto, É. M., & García, Ó. (2011) · Revista de la Facultad de Medicina · Cited by 3
Systematic review and meta‐analysis of randomised, controlled trials on the effects of garlic supplementation on serum adiponectin and leptin levels
Shekarchizadeh, P., Hassani, B., Roshanravan, N., & Sorraya, N. (2021) · International Journal of Clinical Practice · doi:10.1111/ijcp.14200 · Cited by 3
DNA, Nuclear Cell Signaling and Neurodegeneration
Adams, J. D., Jr. (2011) · Royal Society of Chemistry eBooks · doi:10.1039/bk9781849733434-00175 · Cited by 3
Effect of Resistance Training on Body Composition, Bone Mineral Density and Adipocytokine in Obese Perimenopausal Women
Suk, M., shinyuna, 임강일, & Jung, D. (2009) · Korean Journal of Sport Science · doi:10.24985/kjss.2009.20.4.693 · Cited by 3
Potential effect of physical exercise and consumption of micronutrients during pregnancy on the placental and maternal factors associated with chronic non-communicable diseases in adult
Echeverri, I., Ramírez‐Vélez, R., Ortega, J. G., Mosquera, M., Mateus, J. C., & de Plata, A. C. A. (2012) · Univalle Digital Repository (University of Valle) · Cited by 3
Cardiorespiratory Fitness and the Metabolic Syndrome
McAuley, P. A., & Blair, S. N. (2011) · Wiley eBooks · doi:10.1002/9781444347319.ch10 · Cited by 3
The Effect of High-Intensity Interval Training on the Adiponectin and TNF-α Levels of Serum and Adipose Tissues in Rats Fed with a High-Fat Diet Plus Sucrose Solution
Delpisheh, A., & Safarzade, A. (2022) · Shiraz E-Medical Journal · doi:10.5812/semj-119373 · Cited by 2
Short-term effects of moderate intensity physical activity in patients with metabolic syndrome Efeitos de curto prazo de um programa de atividade física moderada em pacientes com síndrome metabólica
Colombo, C., de Macedo, R. M., Fernandes-Silva, M. M., Caporal, A. M., Stinghen, A. E. M., Costantini, C., Baena, C. P., Guarita-Souza, L. C., & Faria‐Neto, J. R. (2013) · Cited by 2
Influence of 9-Weeks Aerobic Exercise and Multivitamin Supplement on Inflammation Biomarkers as Cardiovascular Risk Factor in Non-athletic Obese Women
Tartibian, B., Zahra, G. G., Gaeini, A. A., & ‌Azar, J. T. (2013) · DOAJ (DOAJ: Directory of Open Access Journals) · Cited by 2
Recent advances in the adaptations of adipose tissue to physical activity: Morphology and adipose tissue cellularity
Izawa, T., Ogasawara, J., Sakurai, T., Nomura, S., Kizaki, T., & Ohno, H. (2012) · The Journal of Physical Fitness and Sports Medicine · doi:10.7600/jpfsm.1.381 · Cited by 2
Multimodal treatment of skin during hormonal changes
Dennison, T. (2025) · Journal of Aesthetic Nursing · doi:10.12968/joan.2024.0025 · Cited by 1
THE EFFECTS OF THE TYPE OF EXERCISE ON LIPID PROFILES AND ADIPONECTIN LEVEL IN SEDENTARY MEN
Azarbayjani, M. A., Abedi, B., Peeri, M., Rasaee, M. J., & Ostojić, S. M. (2012) · University of Zagreb University Computing Centre (SRCE) · Cited by 1
The Effect of Aerobic Training with Milk Consumption on Chemerin Resistin and CRP Levels in Prepubertal Children
Farzanegi, P., Esmaeili, B., & Barari, A. (2016) · journal of ilam university of medical sciences · doi:10.18869/acadpub.sjimu.24.2.27 · Cited by 1
Effect of High-Intensity Interval Training on Leptin, Adiponectin, and Leptin/Adiponectin Ratio in Overweight Adolescent Boys
Khanevari, T., Rohani, H., Vakili, J., & Sarraf, V. S. (2021) · یافته · doi:10.32592/yafteh.2021.23.3.5 · Cited by 1
Effects of Stepper Exercise on Physical Fitness and Blood Lipids in Pre-and Post-Menopausal Obese Women
Kang, W.-G. (2018) · 한국체육학회지 · doi:10.23949/kjpe.2018.11.57.6.20 · Cited by 1
Prevalência da síndrome metabólica e fatores associados na transição e após a menopausa
Schmitt, A. C. B. (2009) · doi:10.11606/t.6.2009.tde-13042009-141352 · Cited by 1
Associations between adipocytokines and severity of cardiovascular autonomic neuropathy in well-controlled type 2 diabetes and prediabetesPreprint
Lai, Y., Chiu, W.-C., Cheng, B., Chen, J., Tsai, N., Huang, C., & Lu, C. (2020) · doi:10.21203/rs.3.rs-27650/v1 · Cited by 1
Bone markers and cytokines in response to low-impact, high-intensity exercise
Mezil, Y. (2014) · Brock University Digital Repository (Brock University)
Helping Elders Living with Pain (HELP)
Leveille, S. G., & You, T. (2015)
Self-citation
Efeitos do treinamento de força e da suplementação de tributirina sobre os parâmetros da caquexia em ratos inoculados com tumor de Walker 256.
Donatto, F. F. (2014) · doi:10.11606/t.42.2014.tde-26062014-200642
CHANGES OF PLASMA VISFATIN AND INSULIN RESISTANCE IN OVERWEIGHT AND OBESE NON-ATHLETE ADOLESCENTS FOLLOWING AN EIGHT-WEEK-ENDURANCE ROPE TRAINING
Ghasemnian, A., Kordi, M. R., Ghaeini, A., Ghorbanian, B., & Hedayati, M. (2014) · Journal of Advances in Medical and Biomedical Research

Authors: You, T., & Nicklas, B. J.
Affiliations: University at Buffalo, State University of New York (US)
Corresponding author: You, Tongjian
ORCID: You, Tongjian
Nicklas, Barbara J.
Venue: Current Diabetes Reports
Publisher: Springer Science and Business Media LLC
Published: 2008-02
Volume: 8
Issue: 1
Pages: 7-11
ISSN: 1534-4827 (ISSN-L)
1539-0829
DOI: 10.1007/s11892-008-0003-4
OpenAlex: W2158995409
Cited by: 112
References: 50
Citations by year: 2026: 1 · 2025: 2 · 2023: 3 · 2022: 3 · 2021: 8 · 2020: 7 · 2019: 6 · 2018: 6 · 2017: 4 · 2016: 4 · 2015: 5 · 2014: 12 · 2013: 11 · 2012: 8
FWCI: 1.14
Type: journal article
Language: en
Open access: closed
Licence: www.springer.com/tdm (tdm)
Locations: Current Diabetes Reports (publishedVersion)
PubMed (publishedVersion)
Funders: National Institute on Aging (R01-AG/DK20583, P30AG-21332, P30AG021332)
Topics: Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Adipokines, Inflammation, and Metabolic Diseases
Health Sciences › Medicine › Physiology (medical) › Exercise and Physiological Responses
Health Sciences › Medicine › Physiology (medical) › Adipose Tissue and Metabolism
Keywords: adipokines, metabolic syndrome, aerobic exercise, hypocaloric diet, adiponectin, inflammatory cytokines, adipose tissue inflammation, exercise training, mononuclear cells, obesity
MeSH terms: Diet, Humans, Exercise, Metabolic Syndrome, Caloric Restriction, Adipokines

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Effects of exercise on adipokines and the metabolic syndrome

Abstract

Overview

Integrity signals

Verification

Claims the paper makes

Claims other papers make about this one

Citations

Cites

Cited by

Related

Metadata

Record

About these checks