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Challenges and Opportunities in Global Mental Health: a Research-to-Practice Perspective
Open accessAbstract
Purpose of review Globally, the majority of those who need mental health care worldwide lack access to high-quality mental health services. Stigma, human resource shortages, fragmented service delivery models, and lack of research capacity for implementation and policy change contribute to the current mental health treatment gap. In this review, we describe how health systems in low- and middle-income countries (LMICs) are addressing the mental health gap and further identify challenges and priority areas for future research.Recent findings Common mental disorders are responsible for the largest proportion of the global burden of disease; yet, there is sound evidence that these disorders, as well as severe mental disorders, can be successfully treated using evidence-based interventions delivered by trained lay health workers in low-resource community or primary care settings. Stigma is a barrier to service uptake. Prevention, though necessary to address the mental health gap, has not solidified as a research or programmatic focus. Research-to-practice implementation studies are required to inform policies and scale-up services. Four priority areas are identified for focused attention to diminish the mental health treatment gap and to improve access to high-quality mental health services globally: diminishing pervasive stigma, building mental health system treatment and research capacity, implementing prevention programs to decrease the incidence of mental disorders, and establishing sustainable scale up of public health systems to improve access to mental health treatment using evidence-based interventions.
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“it became apparent in our framework refinement process that, particularly in mental health, stigma (e.g. self-stigma, family/community stigma, provider stigma, organizational or institutional-level stigma) is a force that can exert powerful influences on perceptions of mental health issues and treatments across all social actors and processes—including those in the intervention domain [39–42].”
From Barriers and facilitators to implementation of evidence-based task-sharing mental health interventions in low- and middle-income countries: a systematic review using implementation science frameworks (2022) · cites this paper as [42]
Experimental — accuracy not yet measuredIn the citing paper
“existing models of mental health care will not adequately expand to meet the demand”
From The Opportunities and Risks of Large Language Models in Mental Health (2024) · cites this paper as [4]
In the citing paper
“Further, these studies seldom address sustainability by evaluating the mental health research-to-practice gap or leveraging human resources not dependent on research funding.4”
From Technology and implementation science to forge the future of evidence-based psychotherapies: The PRIDE scale-up study (2021) · cites this paper as [4]
In the citing paper
“This has led to a widely recognized mental health treatment gap, whereby more individuals are diagnosed with mental health problems than those who receive treatment [14, 15].”
From Explaining adults’ mental health help-seeking through the lens of the theory of planned behavior: A scoping review (2022) · cites this paper as [15]
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Therapy Bot: A Multimodal Stress/Emotion Recognition and Alleviation System
Tiwari, P., & Darji, A. D. (2021) · International Journal of Computer Applications · doi:10.5120/ijca2021921719 · Cited by 1
“Considering the recent times and conditions, face-to-face interactions are becoming more and more strenuous and the worldwide unavailability of mental health staffs [6, 33] has urged the need of creation of a therapy bot.”
The Role of Social Workers in Suicide Prevention Among Military Veterans
Levine, J., & Sher, L. (2021) · Springer eBooks · doi:10.1007/978-3-030-41319-4_77-1 · Cited by 1
Bercero, I. G. (2000) · Información Comercial Española, ICE: Revista de economía · Cited by 1
Blanchard, M. P., Pad, R. A., Groh, C. J., & Huprich, S. K. (2022) · Journal of Clinical Psychology in Medical Settings · doi:10.1007/s10880-022-09846-z · Cited by 1
“, 2007) due to various barriers to treatment such as time, cost, availability of resources (Kohn et al., 2004; Lamb et al., 2012; Wainberg et al., 2017), perceived stigma (Pingitore et al.”
BackgroundAsamoah, K. T., & Dei‐Asamoa, R. (2022) · Case Reports in Psychiatry · doi:10.1155/2022/5415196 · Cited by 1
“Capacity building, among both clinicians and researchers, is key to closing the treatment gap and improving overall care and should not be restricted to psychiatrists and psychologists [7] to prevent recurrence of cases like these.”
BackgroundOver-the-Counter Medications and Their Misuse
Weier, M., Weier, N., & O’Mara, B. (2022) · Springer eBooks · doi:10.1007/978-3-030-67928-6_97-1 · Cited by 1
Innovations in Continuity of Care Among Homeless Persons with Severe Mental Illnesses
Vallath, S., & Padmakar, A. (2021) · Springer eBooks · doi:10.1007/978-3-030-57296-9_149 · Cited by 1
Barbosa, C. G. R., Crisp, A. H., de Oliveira, J. J., Ribeiro, A. G. S. V., Oliveira, M. V. A., & Verlengia, R. (2022) · Revista Brasileira de Atividade Física & Saúde · doi:10.12820/rbafs.27e0257 · Cited by 1
Boherom, A. M. A., & Caelian, M. V. (2022) · Philippine Social Science Journal · doi:10.52006/main.v5i2.501 · Cited by 1
El-said, S. G., Megahed, M. M., & Hamza, H. (2022) · International Egyptian Journal of Nursing Sciences and Research · doi:10.21608/ejnsr.2022.247077 · Cited by 1
“Psychiatric illness is increasing and becoming a major public health problem (Wainberg et al., 2017).”
Backgroundda Silva, V. C., Coêlho, A. A., de Queiroz, A. A. R., Costa, G. M. C., Alchieri, J. C., Arcêncio, R. A., & Uchôa, S. A. D. C. (2022) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph192215148 · Cited by 2
Mental Health and Well-Being Products/Apps and Their Challenges
Sooradas, S., Vatsa, A., Negi, A., Singh, H., Mantri, A., Khedkar, S., & Varshney, R. (2023) · Advances in psychology, mental health, and behavioral studies (APMHBS) book series · doi:10.4018/978-1-6684-7221-7.ch009 · Cited by 1
Zadey, S. (2023) · PLOS Global Public Health · doi:10.1371/journal.pgph.0002017 · Cited by 1
Making the Case for Evidence-Based Leadership and Innovation
Melnyk, B. M., & Raderstorf, T. (2024) · Springer Publishing Company eBooks · doi:10.1891/9780826160720.0001 · Cited by 1
Development and Current Status of ICD-11 Mental, Behavioral, or Neurodevelopmental Disorders
Gäebel, W., Salveridou‐Hof, E., Kresse, A., Kadakia, R. F., & Reed, G. M. (2024) · Cambridge University Press eBooks · doi:10.1017/9781009067287.018 · Cited by 1
Roy, R. N., Kumar, P., Singh, V. K., & Singh, D. N. (2023) · The International Tinnitus Journal · doi:10.5935/0946-5448.20230034 · Cited by 1
“Detained individuals frequently endure an elevated incidence of mental health ailments in contrast to the general populace, thereby fostering an intricate interweaving of mental well-being, the criminal justice apparatus, and the expansive medico-legal terrain 1 .”
BackgroundMachado, F. V., Rech, C. M., Pinto, R. S., Romão, W. D. M., Matias, M. M. M., de Freitas, G. C., & Kujawa, H. A. (2023) · Gerencia y Políticas de Salud · doi:10.11144/javeriana.rgps22.mttc · Cited by 1
Husić, I., & Dautbegović, A. (2024) · Obrazovanje odraslih/Adult Education · doi:10.53617/issn2744-2047.2023.23.1.81 · Cited by 1
Hein, A., Gronauer, S., & Diepold, K. J. (2024) · IEEE International Conference on Acoustics, Speech, and Signal Processing Workshops (ICASSPW) · doi:10.1109/icasspw62465.2024.10627246 · Cited by 1
“Millions of individuals worldwide struggle with psychotic disorders, which significantly impact their quality of life and pose substantial challenges to strained healthcare systems [1].”
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Louis, Y. E., Betson, B., & Auguste, S. (2025) · Cambridge Prisms Global Mental Health · doi:10.1017/gmh.2025.7 · Cited by 1
Johnson, L. N., Anderson, S. R., & Wagner, K. N. (2025) · European Journal of Mental Health · doi:10.5708/ejmh.20.2025.0036 · Cited by 1
“…Interview Survey deemed non-affordability as the biggest predictor of inac-cessibility (Coombs et al., 2021) and another global study found that stigma, policy, lack of human resources, and poor distribution of services decrease the availability of mental health services (Wainberg et al., 2017).”
Pastor-Cisneros, R., Denche-Zamorano, Á. M., la Osa, A. R.-D., & Pereira-Payo, D. (2025) · Psychology Health & Medicine · doi:10.1080/13548506.2025.2496999 · Cited by 1
“Mental health problems are becoming increasingly prevalent in recent years, constituting a threat to global public health (Wainberg et al., 2017).”
Jalilul, S. A. A. J. A. (2025) · SOCIAL PSYCHOLOGY AND HUMAN EXPERIENCE · doi:10.62596/azc29b94 · Cited by 4
Aban, J. L., Okesanya, O. J., & Obeagu, E. I. (2025) · Asia Pacific Journal of Public Health · doi:10.1177/10105395251360154 · Cited by 1
Đedović, J., Tomcuk, A., Miladinović, D., Vlahović, S., & Đurišić, T. (2019) · Engrami · doi:10.5937/engrami1901102q · Cited by 1
Using the quantitative EEG method in predicting the response to treatment of affective disorders
Алексеевич, Г. С., Васильева, С. Н., Simutkin, G. G., Tkacheva, G. D., Oshkina, T. A., Ivanova, S. А., & Bokhan, N. A. (2020) · V M BEKHTEREV REVIEW OF PSYCHIATRY AND MEDICAL PSYCHOLOGY · doi:10.31363/2313-7053-2020-4-26-32 · Cited by 1
La experiencia de implementación de “Cuéntame”: una intervención en salud mental
Zamora-Moncayo, E. C., Baquero, D. C., Alvarez-Frank, N. A., Hinojosa, M. S., Montenegro, E. M., Jara, C. T., & Irigoyen, G. N. (2021) · Esferas · doi:10.18272/esferas.v2i.1985 · Cited by 1
Mind Support: A Systematic Review of Online Peer Support Platforms
Stapper, N., Jimenez, G. B., Abbas, Y. B., & King, M. H. (2021) · Applied Neuroscience and Mental Health · doi:10.31739/anamh.2021.1.21 · Cited by 1
Metadata
- Authors
- Wainberg, M. L., Scorza, P., Shultz, J. M., Helpman, L., Mootz, J. J., Johnson, K. A., Neria, Y., Bradford, J.-M. E., Oquendo, M. A., & Arbuckle, M. R.
- Affiliations
- Columbia University Irving Medical Center (US)
- University of Miami (US)
- Corresponding author
- Wainberg, Milton L.
- ORCID
- Venue
- Current Psychiatry Reports
- Published
- 2017-04-19
- Volume
- 19
- Issue
- 5
- Pages
- 28-28
- ISSN
- 1523-3812 (ISSN-L)
- 1535-1645
- PMC
- PMC5553319
- OpenAlex
- W2606586703
- Cited by
- 875
- References
- 105
- Citations by year
- 2026: 117 · 2025: 179 · 2024: 148 · 2023: 138 · 2022: 111 · 2021: 71 · 2020: 73 · 2019: 24 · 2018: 11 · 2017: 1
- FWCI
- 4.69
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- Current Psychiatry Reports (publishedVersion)
- PubMed (publishedVersion)
- PubMed Central (acceptedVersion)
- Funders
- National Institute of Mental Health (T32MH096724)
- Topics
- Health Sciences › Medicine › Psychiatry and Mental health › Mental Health Treatment and Access
- Social Sciences › Psychology › Clinical Psychology › Psychiatric care and mental health services
- Health Sciences › Health Professions › General Health Professions › Health Policy Implementation Science
- Keywords
- global mental health, mental health treatment gap, access to mental health care, mental health stigma, common mental disorders, severe mental illness, lay health workers, community mental health services, primary care, mental health prevention, implementation research, research capacity building, low- and middle-income countries, mental health policy
- MeSH terms
- Mental Disorders, Health Personnel, Humans, Mental Health, Mental Health Services, Public Health, Global Health
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