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Optimization of Pulsed Electric Fields-Assisted Extraction of Polyphenols from Potato Peels Using Response Surface Methodology
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“[63] indicated that the PEF pretreatment of potato peel tissues greatly enhanced the extraction of phenolics.”
BackgroundInfluentialBhatia, L., Jha, H., Sarkar, T., & Sarangi, P. K. (2023) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph20032318 · Cited by 271
“About 399 mg GAE/g equivalent of polyphenols was effectively extracted using this technique [23].”
BackgroundMethodThe application of PEF technology in food processing and human nutrition
Nowosad, K., Sujka, M., Pankiewicz, U., & Kowalski, R. (2020) · Journal of food science and technology · doi:10.1007/s13197-020-04512-4 · Cited by 173
Pulsed electric field (PEF): Avant-garde extraction escalation technology in food industry
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Food Waste Biorefinery: Pathway towards Circular Bioeconomy
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Carpentieri, S., Soltanipour, F., Ferrari, G., Pataro, G., & Donsì, F. (2021) · Antioxidants · doi:10.3390/antiox10091417 · Cited by 226
“Potato peels Phenolic compounds PEF Pre-treatment: E = 1 kV/cm, W = 5 kJ/kg, treatment time = 6 ms, L/S = 1 mL water/g S/L extraction: Ethanol = 52%, time = 230 min, T = 50 ◦C PEF reduced time, temperature, and solvent, improved the extraction yield (10%) and antioxidant activity (9%) than the untreated sample [34]”
BackgroundPulsed electric field as a promising technology for solid foods processing: A review
Zhang, C., Lyu, X., Arshad, R. N., Aadil, R. M., Tong, Y., Zhao, W., & Yang, R. (2022) · Food Chemistry · doi:10.1016/j.foodchem.2022.134367 · Cited by 179
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“The results of this study support the use of oil-in-water microemulsions for the extraction of β -carotene.”
Arshad, R. N., Abdul‐Malek, Z., Roobab, U., Qureshi, M. I., Khan, N., Ahmad, M. H., Liu, Z., & Aadil, R. M. (2020) · Journal of Food Process Engineering · doi:10.1111/jfpe.13629 · Cited by 95
Carpentieri, S., Jambrak, A. ., Ferrari, G., & Pataro, G. (2022) · Frontiers in Nutrition · doi:10.3389/fnut.2021.792203 · Cited by 84
“This agrees with the observations reported by other authors (13, 26, 30), who stated that PEF did not significantly alter the HPLC-PDA chromatogram profiles of different plant extracts, due to the relatively mild intensity of the applied treatment.”
BackgroundResultPhytochemicals Derived from Agricultural Residues and Their Valuable Properties and Applications
Oleszek, M., Kowalska, I., Bertuzzi, T., & Oleszek, W. A. (2023) · Molecules · doi:10.3390/molecules28010342 · Cited by 81
Current Challenges in the Sustainable Valorisation of Agri-Food Wastes: A Review
Berenguer, C. V., Andrade, C. F. P., Pereira, J. A. M., Perestrelo, R., & Câmara, J. S. (2022) · Processes · doi:10.3390/pr11010020 · Cited by 84
Emerging Processing Technologies for the Recovery of Valuable Bioactive Compounds from Potato Peels
Gaudino, E. C., Colletti, A., Grillo, G., Tabasso, S., & Cravotto, G. (2020) · Foods · doi:10.3390/foods9111598 · Cited by 84
“As highlighted in the study, no significant degradation of polyphenols after PEF (such as chlorogenic, syringic, protocatechuic, caffeic, and p-coumaric acids) was revealed by the HPLC–DAD analyses [54].”
Carpentieri, S., Ferrari, G., & Pataro, G. (2023) · Frontiers in Nutrition · doi:10.3389/fnut.2023.1158019 · Cited by 73
“For each treatment condition investigated, the Zp value, ranging from 0 (for intact tissue) to 1 (for fully permeabilized tissue), was calculated using Equation (1) (32):”
BackgroundMethodResultInfluentialPolyphenol Extraction from Food (by) Products by Pulsed Electric Field: A Review
Athanasiadis, V., Chatzimitakos, T. G., Κωτσού, Κ., Kalompatsios, D., Bozinou, E., & Lalas, S. I. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms242115914 · Cited by 71
“To improve the extraction of polyphenols with significant antioxidant properties from potato peels, Frontuto et al. [125] studied the optimal PEF-assisted extraction conditions.”
BackgroundSustainability challenges in the valorization of agri-food wastes and by-products
Bhat, R. (2021) · Elsevier eBooks · doi:10.1016/b978-0-12-824044-1.00022-2 · Cited by 69
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Supercritical Carbon Dioxide Extraction of Phenolic Compounds from Potato (Solanum tuberosum) Peels
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“Likewise, Frontuto et al. (2019) employed PEFAE to intensify the extractability of phenolic compounds, obtaining 1.1 mg GAE (gallic acid equivalent)/g FW PP.”
MethodInfluentialPlazzotta, S., Ibarz, R., Manzocco, L., & Martín‐Belloso, O. (2020) · Journal of Food Engineering · doi:10.1016/j.jfoodeng.2020.110196 · Cited by 48
Brahmi, F., Mateos‐Aparicio, I., García‐Alonso, A., Abaci, N., Saoudi, S., Smail-Benazzouz, L., Haddadi‐Guemghar, H., Madani, K., & Boulekbache‐Makhlouf, L. (2022) · Antioxidants · doi:10.3390/antiox11071401 · Cited by 51
Valorisation of food processing wastes using PEF and its economic advances – recent update
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“Several works have explored different waste-stream valorization using PEF such as spent brewer’s grains [37,38], citrus peels [15,39], sesame cake [40], potato peels [41], apple peels [42], and peach wastes [43].”
BackgroundSaini, R., Kaur, S., Aggarwal, P., Dhiman, A., & Suthar, P. (2023) · Food Control · doi:10.1016/j.foodcont.2023.109933 · Cited by 38
Ohmic Heating–Assisted Extraction of Natural Color Matters from Red Beetroot
Çabas, B. M., & İçıer, F. (2021) · Food and Bioprocess Technology · doi:10.1007/s11947-021-02698-9 · Cited by 37
“, 2014), potato peel (Frontuto et al., 2019), and red grape pomace (El Darra et al.”
BackgroundCarpentieri, S., Mazza, L., Nutrizio, M., Jambrak, A. ., Ferrari, G., & Pataro, G. (2021) · International Journal of Food Science & Technology · doi:10.1111/ijfs.15159 · Cited by 35
“…in comparison with pure water (Nutrizio et al., 2020b,c), along with the capability of ethanol to affect barrier properties of the cell membrane (Frontuto et al., 2019), which likely favoured extraction by enhancing solubility of polyphenols with a broad spectrum of polarity and the capacity…”
BackgroundMethodEstablishment of a Sonotrode Ultrasound-Assisted Extraction of Phenolic Compounds from Apple Pomace
Razola‐Díaz, M. D. C., Aznar‐Ramos, M. J., Guerra-Hernández, E. J., García‐Villanova, B., Gómez‐Caravaca, A. M., & Verardo, V. (2022) · Foods · doi:10.3390/foods11233809 · Cited by 33
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“Up to date, PEF there are multiple reports regarding the use of PEF for the extraction of compounds from plant material, such as the extraction of polyphenols from olive leaves [19], tea leaves [20], citrus fruits [21], potato peels [22] and Merlot grapes [23].”
BackgroundLeyva‐Jiménez, F. J., Fernández‐Ochoa, Á., Cádiz‐Gurrea, M. D. L. L., Lozano‐Sánchez, J., Oliver‐Simancas, R., Alañón, M. E., Castangia, I., Segura‐Carretero, A., & Arraéz-Román, D. (2022) · Antioxidants · doi:10.3390/antiox11081552 · Cited by 31
“PEF Ethanol concentration (%) Extraction time (min) Temperature (◦C) 0–100% 30–240 min 20–50◦C 15 TPC DPPH Model adequacy Lack-of-fit R2 Potato peel [43]”
BackgroundMakrygiannis, I., Athanasiadis, V., Bozinou, E., Chatzimitakos, T. G., Makris, D. P., & Lalas, S. I. (2023) · Biomass · doi:10.3390/biomass3010005 · Cited by 24
“These percentages are relatively higher compared to other studies [39,40].”
BackgroundResultAdvances in pulsed electric stimuli as a physical method for treating liquid foods
Zare, F., Ghasemi, N., Bansal, N., & Hosano, H. (2023) · Physics of Life Reviews · doi:10.1016/j.plrev.2023.01.007 · Cited by 25
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“For this reason, numerous efforts are still being made to improve extraction protocols and technology-aided approaches for the recovery of valuable compounds from potato by-products, in more sustainable, energy-efficient, and cost-effective ways [4,5].”
BackgroundJara-Quijada, E., Pérez‐Won, M., Tabilo‐Munizaga, G., González-Cavieres, L., Palma-Acevedo, A., Herrera‐Lavados, C., & Lemus-Mondaca, R. A. (2023) · Food and Bioprocess Technology · doi:10.1007/s11947-023-03286-9 · Cited by 21
“This design has been used for PEF-assisted extraction of polyphenols in matrices such as blackcurrant (Gagneten et al., 2019), potato peel (Frontuto et al., 2019), cocoa bean shell, and coffee silver skin (Barbosa-Pereira et al., 2018), among others.”
Lakka, A., Lalas, S. I., & Makris, D. P. (2020) · Applied Sciences · doi:10.3390/app10103611 · Cited by 20
“However, intermediate levels of 50 ◦C have also been suggested [37].”
BackgroundGrillo, G., Tabasso, S., Capaldi, G., Radošević, K., Redovniković, I. R., Gunjević, V., Gaudino, E. C., & Cravotto, G. (2023) · Foods · doi:10.3390/foods12112214 · Cited by 21
“The most promising innovative extraction techniques documented in the literature include Microwave-Assisted Extraction (MAE) [27,28], Ultrasound-Assisted Extraction (UAE) [29,30], Supercritical Fluid Extraction (SFE) [31], Pulsed Electric Fields (PEF) [32,33], Pressurised-Liquid Extraction (PLE), and Subcritical Water…”
BackgroundSustainable Extraction Technology of Fruit and Vegetable Residues as Novel Food Ingredients
Zheng, S., Huang, Z., Dong, L., Li, D., Hu, X., Chen, F., & Ma, C. (2025) · Foods · doi:10.3390/foods14020331 · Cited by 19
“Frontuto et al. [117] reported that pretreatment with the PEF at 1 kV/cm and 5 kJ/kg was sufficient to achieve a high level of potato pericarp tissue permeability, which resulted in the improved recovery of phenolic compounds during conventional extraction, with a total phenol content of 1180 mg…”
Younis, M., Ahmed, I. A. M., Ahmed, K. A., Yehia, H. M., Abdelkarim, D. O., Fickak, A. A., El-Abedein, A. I. Z., Alhamdan, A. M. A., & Elfeky, A. M. (2023) · Horticulturae · doi:10.3390/horticulturae9020155 · Cited by 19
Review of Developments in Bioelectrics as an Application of Pulsed Power Technology
Joshi, R. P., Garner, A. L., & Sundararajan, R. (2023) · IEEE Transactions on Plasma Science · doi:10.1109/tps.2023.3281339 · Cited by 19
“PEFs have also been successfully applied to extract polyphenols from olive leaves with various green solvents [208], [209], grape stems [210], white grape pomace [211], potato peels [212], and other plants [213].”
MethodElsayed, N., Hammad, K. S. M., & El-Salam, E. A. E.-S. A. (2020) · Journal of Food Processing and Preservation · doi:10.1111/jfpp.14813 · Cited by 18
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“Additionally, Frontuto et al. (2019) observed that PEF pre-treatment at 1 kV/cm and at 5 kJ/kg is sufficient to achieve high level of potato peel tissue permeabilization, thus inten-sifying the recovery yield of phenolic compounds during the conventional extraction process.”
Xu, L., Zhu, S., Wan, W., Yu, M. Y., Zeng, X., & Deng, Z. (2024) · Journal of the Science of Food and Agriculture · doi:10.1002/jsfa.13494 · Cited by 17
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“Frontuto et al. 69 have also recorded disruption and deconstruction of PPW after using pulse electric field assisted extraction techniques.”
MethodNabiyevа, Z. S., Kulaipbekova, A., Carpentieri, S., Pronina, Y., Samadun, A. I., Assembayeva, E., & Ferrari, G. (2025) · Antioxidants · doi:10.3390/antiox14081003 · Cited by 16
“This type of ethanol-dependent behavior is well-documented in studies investigating the extractability of phenolic compounds from plant-based biomasses, where a mixed-polarity solvent maximized extraction yield [15,25].”
Pappas, V. M., Palaiogiannis, D., Athanasiadis, V., Chatzimitakos, T. G., Bozinou, E., Makris, D. P., & Lalas, S. I. (2022) · Oxygen · doi:10.3390/oxygen2040035 · Cited by 16
Palaiogiannis, D., Athanasiadis, V., Bozinou, E., Chatzimitakos, T. G., Makris, D. P., & Lalas, S. I. (2022) · Compounds · doi:10.3390/compounds2040026 · Cited by 19
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Evaluation of the Effect of Pulsed Electric Field on Coffee Arabica Beans
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Boateng, I. D. (2023) · Journal of Food and Drug Analysis · doi:10.38212/2224-6614.3479 · Cited by 17
“Comparable fi ndings have been reported on PEF extraction of lemon peel ' s polyphenols [161], tepals of Crocus sativus [168], olive pomace [163], Sideritis raiseri [169], apple pomace [170], banana peels [171] and potato peels [162].”
BackgroundMethodCarullo, D., Carpentieri, S., Ferrari, G., & Pataro, G. (2024) · Journal of Food Engineering · doi:10.1016/j.jfoodeng.2024.111939 · Cited by 15
Recent Advances in the Extraction of Phenolic Compounds from Food Wastes by Emerging Technologies
Okur, P. S., & Okur, İ. (2024) · Food and Bioprocess Technology · doi:10.1007/s11947-024-03365-5 · Cited by 15
“Peiró et al. (2019) showed that total phenolic content (TPC) , Frontuto et al. (2019) showed that PEFAE increased protocatechuic, chlorogenic, caffeic, syringic, and p -cou- maric acids content compared to conventional techniques.”
Addressing the opportunities of non-thermal food processing technologies in the ASEAN region context
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Encapsulación de extractos antioxidantes desde sub-productos agroindustriales: una revisión
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“[31] Papa Snacks, congelados Piel Ácidos fenólicos (ácido clorogénico y ácido cafeico),”
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“The PEF treatment applied to potato peels led to an increase in the rate of extraction of phenolic compounds due to the damage caused to the structure of the cell (Frontuto et al. 2019).”
Volumetric Shrinkage and Poisson ‘s Ratio of Carrot Treated by Pulse Electric Fields
Blahovec, J., Kouřím, P., & Lebovka, N. (2021) · Food and Bioprocess Technology · doi:10.1007/s11947-021-02711-1 · Cited by 8
Rrucaj, E., Carpentieri, S., Siano, F., Ferrari, G., & Pataro, G. (2023) · Frontiers in Food Science and Technology · doi:10.3389/frfst.2023.1273243 · Cited by 7
Advancements in food waste valorization through ultrasound-assisted extraction: A review
Melikoğlu, M. (2026) · Cleaner Waste Systems · doi:10.1016/j.clwas.2026.100487 · Cited by 7
Carullo, D., Bosi, M., Dermiki, M., Bassani, A., Jauregi, P., & Spigno, G. (2021) · Food and Bioproducts Processing · doi:10.1016/j.fbp.2021.11.007 · Cited by 7
UV-Assisted Autolysis for Nutrient Bioconversion of Sea Cucumber (Stichopus horrens) Body Wall
Umam, N. I., Sulaiman, A., Wong, Y. F., Jaya-Ram, A., Woo, S. P., & Zulkurnain, M. (2023) · Food and Bioprocess Technology · doi:10.1007/s11947-023-03227-6 · Cited by 7
“Response surface methodol - ogy (RSM) utilizes a second-order polynomial equation in multiple regression to effectively captures and analyze inter - action effects among parameters studied (Frontuto et al., 2019 ).”
Sinthusamran, S., Chotphruethipong, L., Benjakul, S., Hutamekalin, P., Champoochana, N., Senphan, T., & Nalinanon, S. (2024) · Applied Food Research · doi:10.1016/j.afres.2024.100428 · Cited by 7
Hu, Y., Qian, W.-Z., Fan, S., Yang, Y., Liao, H., Zhuang, G., & Gao, S. (2024) · Molecules · doi:10.3390/molecules29143280 · Cited by 7
“Moreover, the solid surface of dried extracts from LSF at PGS I seems to have less protrusions and roughness, and the shape is more irregular than that at PGS II and PGSIII. carotenoids, 2+ complexed, findings, it stage may be of harvest relatively variability of bioactive components in LSF.”
BackgroundPotato peels as feedstock for laccase-catalysed synthesis of phellinsin A
Nemadziva, B., Ngubane, S., Ruzengwe, F. M., Kasumbwe, K., & Kudanga, T. (2022) · Biomass Conversion and Biorefinery · doi:10.1007/s13399-021-02251-w · Cited by 6
“Extraction of CLA from potato peels is affected by process parameters such as solvent type and concentration, solvent to material ratio, ultrasonication power and the extraction time [17–20].”
Baiano, A., Pilli, T. D., & Fiore, A. G. (2024) · Journal of Food Process Engineering · doi:10.1111/jfpe.14617 · Cited by 6
Potato Processing Waste as a Reservoir of Bioactive Hydroxycinnamates: A Critical Review
Makris, D. P. (2024) · Biomass · doi:10.3390/biomass5010002 · Cited by 5
“This was also the case for the application of subcritical water [64], pulsed electric field pretreatment [66], and infrared-assisted extraction [48].”
Shaheen, S., Grigorakis, S., Halahlah, A., Loupassaki, S., & Makris, D. P. (2020) · Chemical Engineering Communications · doi:10.1080/00986445.2020.1805438 · Cited by 5
“Levels of CEtOH of 54% were also reported for pulsed-electric field pretreated samples, extracted at 50 C (Frontuto et al. 2019).”
BackgroundRecent advances in extraction, isolation, characterization, and applications of phenolic compounds
Routray, W., Jena, B. S., & Orsat, V. (2022) · Studies in natural products chemistry · doi:10.1016/b978-0-12-823944-5.00006-5 · Cited by 5
Innovative processes for the extraction of bioactive compounds from winery wastes and by-products
Pataro, G., Carullo, D., & Ferrari, G. (2022) · Elsevier eBooks · doi:10.1016/b978-0-323-85150-3.00004-9 · Cited by 5
Dhar, P., Raj, B. J. R., Dasarathy, D. A. K., Das, P., Singhe, S., Palanivelu, E., Sinha, A., Puppala, R., & Abate, L. (2025) · Engineering Reports · doi:10.1002/eng2.70539 · Cited by 4
Mahajan, A., Sharma, P., Goudar, G., Gogoi, P., & Sasikumar, R. (2026) · Critical Reviews in Food Science and Nutrition · doi:10.1080/10408398.2026.2676735 · Cited by 4
Sustainable Solutions: Navigating Agrifood Waste with Eco-smart Approaches for a Greener Environment
Singh, M. P., Kumar, P., Pal, P., Kumari, B., Prakash, O., Singh, A. K., Sarangi, P. K., Pandey, B., & Prakash, A. (2024) · Springer eBooks · doi:10.1007/978-3-031-58441-1_5 · Cited by 5
Krishnegowda, R., Sharma, M., & Ravindra, M. R. (2023) · International Journal of Dairy Technology · doi:10.1111/1471-0307.12997 · Cited by 4
Verhulst, E. P., Brunton, N. P., & Rai, D. K. (2025) · Innovative Food Science & Emerging Technologies · doi:10.1016/j.ifset.2025.104415 · Cited by 3
Hu, X., Sun, Y., Wang, H., Rahman, K. U., Chen, Y., Li, C., Chi, X., & Cui, Z. (2026) · Microchemical Journal · doi:10.1016/j.microc.2026.118602 · Cited by 3
Li, X., Han, H., Ma, Y., Wang, X., & Lü, X. (2024) · Journal of Food Science · doi:10.1111/1750-3841.17060 · Cited by 3
Recent developments in pulsed electric field processing of foods
Noore, S., Tiwari, B. K., Töpfl, S., & O’Donnell, C. P. (2024) · Elsevier eBooks · doi:10.1016/b978-0-443-22182-8.00009-7 · Cited by 2
Dramićanin, A., Horvacki, N., Gašić, U. M., & Milojković‐Opsenica, D. (2025) · Processes · doi:10.3390/pr13020396 · Cited by 2
Review on the Application of Pulsed Electric Field in Some Fruit and Vegetable Processing
Gudeta, R. L. (2023) · International Journal of Food Engineering and Technology · doi:10.11648/j.ijfet.20230702.11 · Cited by 2
Usos de los subproductos de la papa en la industria alimentaria: RSL
Inga, H. J. C., Gonzales, L. C. S., León, D. E. A., & Cerna, C. O. L. (2024) · TAYACAJA · doi:10.46908/tayacaja.v7i1.219 · Cited by 2
Engineering and Nonthermal Technologies: Process Optimization Through Kinetic Modelling
Katsaros, G. I., Andreou, V., & Giannoglou, M. (2022) · Food engineering series · doi:10.1007/978-3-030-92415-7_3 · Cited by 2
Metadata
- Authors
- Frontuto, D., Carullo, D., Harrison, S. M., Brunton, N. P., Ferrari, G., Lyng, J. G., & Pataro, G.
- Affiliations
- University College Dublin (IE)
- University of Salerno (IT)
- Corresponding author
- Pataro, G.
- Venue
- Food and Bioprocess Technology
- Published
- 2019-08-27
- Volume
- 12
- Issue
- 10
- Pages
- 1708-1720
- ISSN
- 1935-5130 (ISSN-L)
- 1935-5149
- OpenAlex
- W2970689289
- Cited by
- 129
- References
- 39
- Citations by year
- 2026: 23 · 2025: 13 · 2024: 22 · 2023: 27 · 2022: 23 · 2021: 12 · 2020: 9
- FWCI
- 6.66
- Type
- journal article
- Language
- en
- Open access
- green
- hdl.handle.net
- Licence
- Locations
- Food and Bioprocess Technology (publishedVersion)
- Archivio Istituzionale della Ricerca (Universita Degli Studi Di Milano) (submittedVersion, other-oa)
- Topics
- Health Sciences › Medicine › Biochemistry (medical) › Phytochemicals and Antioxidant Activities
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Biotechnology › Microbial Inactivation Methods
- Life Sciences › Agricultural and Biological Sciences › Food Science › Agricultural and Biological Research
- Keywords
- pulsed electric field, potato peel, polyphenol extraction, solid-liquid extraction, cell disintegration, ethanol-water solvent, extraction optimization, antioxidant activity, total phenolic content, chlorogenic acid, caffeic acid, syringic acid, protocatechuic acid, p-coumaric acid, food by-product valorization
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