CoChat
Sign Up
Cited by 27

The DOI matches its Crossref record; 6 of the 6 references it cites were found in a registry or an index.

Fluoride-Induced Alteration in the Diversity and Composition of Bacterial Microbiota in Mice Colon

Fu, Rong, Niu, Ruiyan, Li, Rui, Yue, Baijuan, Zhang, Xuhua, Cao, Qiqi, Wang, Jundong, Sun, Zilong·2020·Biological Trace Element Research
DOI 10.1007/s12011-019-01942-w
Open this paper in CoChat — free account

Abstract

Fluoride, as an environmental toxin, causes damage to intestinal mucosa. It may promote pathogen infection by increasing the intestinal mucosa permeability. In this study, the colonic fecal samples from the control group (C group, 0 mg/L NaF for 60 days) and the fluoride group (F group, 100 mg/L NaF for 60 days) were subjected to high-throughput 16S rRNA sequencing to verify the effects of fluoride on the colonic flora of animals. Results revealed a total of 253 operative taxonomical units (OTUs) in two groups, and 22 unique OTUs occurred in the F group. Fluoride increased the microbiota diversity and species richness of the colon. Concretely, the abundance of the Tenericutes was increased at the level of the phyla in the F group. In addition, in the F group, significant differences at the genus level were observed in Faecalibaculum, Alloprevotella, [Eubacterium]_xylanophilum_group, Prevotellaceae_UCG-001, and Ruminiclostridium_9, compared to the C group. Among them, except for the reduction in Faecalibaculum, the other four bacteria were increased in the F group. In summary, the intestinal microbial composition of mice was reconstituted by the presence of fluoride, and the significantly changing bacteria may partly account for the pathogenesis of fluoride-induced intestinal dysfunction.

Overview

Integrity signals

Registry

Crossref · 10.1007/s12011-019-01942-w

Cites

6 of 6 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Verification

Claims the paper makes

This paper’s full text isn’t openly available, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Citations

Cites

Show all 6 references

Research works printed but not linked: 28

  1. Jha SK, Mishra VK, Sharma DK, Damodaran T (2011) Fluoride in the environment and its metabolism in humans. Rev Environ Contam Toxicol 211:121–142
  2. Rashid A, Guan DX, Farooqi A, Khan S, Zahir S, Jehan S, Khattak SA, Khan MS, Khan R (2018) Fluoride prevalence in groundwater around a fluorite mining area in the flood plain of the River Swat, Pakistan. Sci Total Environ 635:203–215 · DOI
  3. Jagtap S, Yenkie MK, Labhsetwar N, Rayalu S (2012) Fluoride in drinking water and defluoridation of water. Chem Rev 112(4):2454–2466 · DOI
  4. Sharma D, Singh A, Verma K, Paliwal S, Sharma S, Dwivedi J (2017) Fluoride: A review of pre-clinical and clinical studies. Environ Toxicol Pharmacol 56:297–313 · DOI
  5. Death CE, Coulson G, Hufschmid J, Morris WK, Gould J, Stevenson M (2019) When less is more: a comparison of models to predict fluoride accumulation in free-ranging kangaroos. Sci Total Environ 660:531–540 · DOI
  6. Whitford GM (1996) The metabolism and toxicity of fluoride. Monogr Oral Sci 16 Rev 2:1–153
  7. Wang H, Liu J, Zhao W, Zhang Z, Li S, Li S, Zhu S, Zhou B (2019) Effect of fluoride on small intestine morphology and serum cytokine contents in rats. Biol Trace Elem Res 189(2):511–518 · DOI
  8. Luo Q, Cui H, Peng X, Fang J, Zuo Z, Deng J, Liu J, Deng Y (2013) Intestinal IgA+ cell numbers as well as IgA, IgG, and IgM contents correlate with mucosal humoral immunity of broilers during supplementation with high fluorine in the diets. Biol Trace Elem Res 154(1):62–72 · DOI
  9. Luo Q, Cui H, Peng X, Fang J, Zuo Z, Deng J, Liu J, Deng Y (2013) Suppressive effects of dietary high fluorine on the intestinal development in broilers. Biol Trace Elem Res 156(1-3):153–165 · DOI
  10. Kim YS, Ho SB (2010) Intestinal goblet cells and mucins in health and disease: recent insights and progress. Curr Gastroenterol Rep 12(5):319–330 · DOI
  11. Kitajima S, Morimoto M, Sagara E, Shimizu C, Ikeda Y (2001) Dextran sodium sulfate-induced colitis in germ-free IQI/Jic mice. Exp Anim 50(5):387–395 · DOI
  12. Barko PC, Mcmichael MA, Swanson KS, Williams DA (2018) The gastrointestinal microbiome: A review. J Vet Intern Med 32(1):9–25 · DOI · Paper page
  13. Tilocca B, Burbach K, Heyer CME, Hoelzle LE, Mosenthin R, Stefanski V, Camarinha-Silva A, Seifert J (2017) Dietary changes in nutritional studies shape the structural and functional composition of the pigs’ fecal microbiome-from days to weeks. Microbiome 5(1):144 · DOI
  14. Lozupone CA, Stombaugh JI, Gordon JI, Jansson JK, Knight R (2012) Diversity, stability and resilience of the human gut microbiota. Nature 489(7415):220–230 · DOI · Paper page
  15. Liu J, Wang H, Lin L, Miao C, Zhang Y, Zhou B (2019) Intestinal barrier damage involved in intestinal microflora changes in fluoride-induced mice. Chemosphere 234:409–418 · DOI · Paper page
  16. Qi Y, Sun J, Ren L, Cao X, Dong J, Tao K, Guan X, Cui Y, Su W (2019) Intestinal microbiota is altered in patients with gastric cancer from Shanxi Province, China. Dig Dis Sci 64(5):1193–1203 · DOI
  17. Follin-Arbelet B, Moum B (2016) Fluoride: a risk factor for inflammatory bowel disease? Scand J Gastroenterol 51(9):1019–1024 · DOI
  18. Lloyd-Price J, Abu-Ali G, Huttenhower C (2016) The healthy human microbiome. Genome Med 8(1):51 · DOI · Paper page
  19. Augenstein WL, Spoerke DG, Kulig KW, Hall AH, Hall PK, Riggs BS, Saadi M, El RBH (1991) Fluoride ingestion in children: a review of 87 cases. Pediatrics 88(5):907–912 · DOI
  20. Kim HB, Isaacson RE (2015) The pig gut microbial diversity: Understanding the pig gut microbial ecology through the next generation high throughput sequencing. Vet Mmicrobiol 177(3-4):242–251 · DOI
  21. Wan X, Bi J, Gao X, Tian F, Wang X, Li N, Li J (2015) Partial enteral nutrition preserves elements of gut barrier function, including innate immunity, intestinal alkaline phosphatase (IAP) level, and intestinal microbiota in mice. Nutrients 7(8):6294–6312 · DOI
  22. Ma H, Zhang B, Hu Y, Wang J, Liu J, Qin R, Lv S, Wang S (2019) Correlation analysis of intestinal redox state with the gut microbiota reveals the positive intervention of tea polyphenols on hyperlipidemia in high-fat diet fed mice. J Agric Food Chem 67(26):7325–7335 · DOI
  23. Chen W, Liu F, Ling Z, Tong X, Xiang C (2012) Human intestinal lumen and mucosa-associated microbiota in patients with colorectal cancer. PLoS One 7(6):e39743 · DOI
  24. Ke X, Walker A, Haange SB, Lagkouvardos I, Liu Y, Schmitt-Kopplin P, von Bergen M, Jehmlich N, He X, Clavel T, Cheung PCK (2019) Synbiotic-driven improvement of metabolic disturbances is associated with changes in the gut microbiome in diet-induced obese mice. Mol Metab 22:96–109 · DOI
  25. Meehan CJ, Beiko RG (2014) A phylogenomic view of ecological specialization in the Lachnospiraceae, a family of digestive tract-associated bacteria. Genome Biol Evol 6(3):703–713 · DOI
  26. Chauhan SS, Mahmood A, Ojha S (2013) Ethanol and age enhances fluoride toxicity through oxidative stress and mitochondrial dysfunctions in rat intestine. Mol Cell Biochem 384(1-2):251–262 · DOI
  27. Kang Y, Li Y, Du Y, Guo L, Chen M, Huang X, Yang F, Hong J, Kong X (2019) Konjaku flour reduces obesity in mice by modulating the composition of the gut microbiota. Int J Obes (Lond) 43(8):1631–1643 · DOI
  28. Yue S, Liu J, Wang W, Wang A, Yang X, Guan H, Wang C, Yan D (2019) Berberine treatment-emergent mild diarrhea associated with gut microbiota dysbiosis. Biomed Pharmacother 116:109002 · DOI

Cited by

Sorted by citations

Metadata

Authors
Fu, R., Niu, R., Li, R., Yue, B., Zhang, X., Cao, Q., Wang, J., & Sun, Z.
ORCID
Venue
Biological Trace Element Research
Publisher
Springer Science and Business Media LLC
Published
2019-11-18
Volume
196
Issue
2
Pages
537-544
ISSN
  • 0163-4984
  • 1559-0720
DOI
10.1007/s12011-019-01942-w
Cited by
27
References
6
Language
en
Licence
Funders
the Top Young Innovative Talents of Shanxi Agricultural University (Grant No. TYIT201408)

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review