Patients with lactose intolerance absorb liquid levothyroxine better than tablet levothyroxine

Autoimmune thyroid disorders

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Thyroxine in Goiter, <i>Helicobacter pylori</i> Infection, and Chronic Gastritis

Centanni, M., Gargano, L., Canettieri, G., Viceconti, N., Franchi, A., Fave, G. D., & Annibale, B. (2006) · New England Journal of Medicine · doi:10.1056/nejmoa043903 · Cited by 329 · see citing works

Altered intestinal absorption of L-thyroxine caused by coffee

Benvenga, S., Bartolone, L., Pappalardo, M. A., Russo, A., Lapa, D., Giorgianni, G., Saraceno, G., & Trimarchi, F. (2008) · Thyroid · doi:10.1089/thy.2007.0222 · Cited by 191 · see citing works

A review of the pharmacokinetics of levothyroxine for the treatment of hypothyroidism

Colucci, P., Yue, C. S., Ducharme, M., Benvenga, S., Principal Scientist, L. A. C. I., Principal Scientist, L. A. C. I. A. P. C., President and CEO, L. A. C. I., & Professor of Medicine, D. (2010) · European Endocrinology · doi:10.17925/ee.2013.09.01.40 · Cited by 167 · see citing works

Switching levothyroxine from the tablet to the oral solution formulation corrects the impaired absorption of levothyroxine induced by proton-pump inhibitors

Vita, R., Saraceno, G., Trimarchi, F., & Benvenga, S. (2014) · The Journal of Clinical Endocrinology &amp; Metabolism · doi:10.1210/jc.2014-2684 · Cited by 99 · see citing works

Clinical and subclinical autoimmune thyroid disorders in systemic sclerosis

Antonelli, A., Ferri, C., Fallahi, P., Cazzato, M., Ferrari, S. M., Sebastiani, M., & Ferrannini, E. (2007) · European Journal of Endocrinology · doi:10.1530/eje-06-0591 · Cited by 95 · see citing works

The administration of l -thyroxine as soft gel capsule or liquid solution

Vita, R., Fallahi, P., Antonelli, A., & Benvenga, S. (2014) · Expert Opinion on Drug Delivery · doi:10.1517/17425247.2014.918101 · Cited by 93 · see citing works

TSH normalization in bariatric surgery patients after the switch from L-Thyroxine in tablet to an oral liquid formulation

Fallahi, P., Ferrari, S. M., Camastra, S., Politti, U., Ruffilli, I., Vita, R., Navarra, G., Benvenga, S., & Antonelli, A. (2017) · Obesity Surgery · doi:10.1007/s11695-016-2247-4 · Cited by 81 · see citing works

A double-blind placebo-controlled trial of liquid thyroxine ingested at breakfast: results of the TICO study

Cappelli, C., Pirola, I., Daffini, L., Formenti, A., Iacobello, C., Cristiano, A., Gandossi, E., Agabiti Rosei, E., & Castellano, M. (2016) · Thyroid · doi:10.1089/thy.2015.0422 · Cited by 80 · see citing works

When thyroid hormone replacement is ineffective?

Benvenga, S. (2013) · Current Opinion in Endocrinology, Diabetes &amp; Obesity · doi:10.1097/med.0000000000000003 · Cited by 74 · see citing works

Systematic appraisal of lactose intolerance as cause of increased need for oral thyroxine

Cellini, M., Santaguida, M. G., Gatto, I., Virili, C., Del Duca, S. C., Brusca, N., Capriello, S., Gargano, L., & Centanni, M. (2014) · The Journal of Clinical Endocrinology &amp; Metabolism · doi:10.1210/jc.2014-1217 · Cited by 72 · see citing works

Decrease in TSH levels after lactose restriction in Hashimoto's thyroiditis patients with lactose intolerance

Asik, M., Gunes, F., Binnetoglu, E., Eroglu, M., Bozkurt, N., Sen, H., Akbal, E., Bakar, C., Beyazit, Y., & Ukinc, K. (2014) · Endocrine · doi:10.1007/s12020-013-0065-1 · Cited by 58 · see citing works

Lactose intolerance revealed by severe resistance to treatment with levothyroxine

Muñoz-Torres, M., Varsavsky, M., & Alonso, G. (2006) · Thyroid · doi:10.1089/thy.2006.16.1171 · Cited by 54 · see citing works

Oral L-thyroxine liquid versus tablet in patients with hypothyroidism without malabsorption: a prospective study

Fallahi, P., Ferrari, S. M., & Antonelli, A. (2016) · Endocrine · doi:10.1007/s12020-015-0836-y · Cited by 53 · see citing works

Celiac Disease Presenting as Resistant Hypothyroidism

McDermott, J. H., Coss, A., & Walsh, C. H. (2005) · Thyroid · doi:10.1089/thy.2005.15.386 · Cited by 48 · see citing works

Reversible normalisation of serum TSH levels in patients with autoimmune atrophic gastritis who received L-T4 in tablet form after switching to an oral liquid formulation: a case series

Fallahi, P., Ferrari, S. M., Ruffilli, I., & Antonelli, A. (2016) · BMC Gastroenterology · doi:10.1186/s12876-016-0439-y · Cited by 46 · see citing works

Comparison of TSH Levels with Liquid Formulation Versus Tablet Formulations of Levothyroxine in the Treatment of Adult Hypothyroidism

Brancato, D., Scorsone, A., Saura, G., Ferrara, L., Di Noto, A., Aiello, V., Fleres, M., & Provenzano, V. (2014) · Endocrine Practice · doi:10.4158/ep13418.or · Cited by 44 · see citing works

The influence of lactose intolerance and other gastro-intestinal tract disorders on L-thyroxine absorption.

Ruchała, M., Szczepanek‐Parulska, E., & Zybek, A. (2012) · PubMed · Cited by 38 · see citing works

Timing of breakfast does not influence therapeutic efficacy of liquid levothyroxine formulation

Morelli, S., Reboldi, G., Moretti, S., Menicali, E., Avenia, N., & Puxeddu, E. (2016) · Endocrine · doi:10.1007/s12020-015-0788-2 · Cited by 30 · see citing works

Atrophic Body Gastritis in Patients With Autoimmune Thyroid Disease: An Underdiagnosed Association

Centanni, M., Marignani, M., Gargano, L., Corleto, V. D., Casini, A., Delle Fave, G., Andreoli, M., & Annibale, B. (1999) · Archives of Internal Medicine · doi:10.1001/archinte.159.15.1726 · Cited by 1 · see citing works

Hashimotos' thyroiditis: epidemiology, pathogenesis, clinic and therapy

Ragusa, F., Fallahi, P., Elia, G., Gonnella, D., Paparo, S. R., Giusti, C., Churilov, L. P., Ferrari, S. M., & Antonelli, A. (2019) · Best Practice &amp; Research Clinical Endocrinology &amp; Metabolism · doi:10.1016/j.beem.2019.101367 · Cited by 655 · see citing works

Gastrointestinal malabsorption of thyroxine

Virili, C., Antonelli, A., Santaguida, M. G., Benvenga, S., & Centanni, M. (2019) · Endocrine Reviews · doi:10.1210/er.2018-00168 · Cited by 164 · see citing works

Levothyroxine therapy: changes of TSH levels by switching patients from tablet to liquid formulation. a systematic review and meta-analysis

Virili, C., Giovanella, L., Fallahi, P., Antonelli, A., Santaguida, M. G., Centanni, M., & Trimboli, P. (2018) · Frontiers in Endocrinology · doi:10.3389/fendo.2018.00010 · Cited by 61 · see citing works

Levothyroxine: conventional and novel drug delivery formulations.

Liu, H., Li, W., Zhang, W., Sun, S., & Chen, C. (2023) · Endocrine Reviews · doi:10.1210/endrev/bnac030 · Cited by 63 · see citing works

Undertreated hypothyroidism due to calcium or iron supplementation corrected by oral liquid levothyroxine

Benvenga, S., Di Bari, F., & Vita, R. (2017) · Endocrine · doi:10.1007/s12020-017-1244-2 · Cited by 51 · see citing works

Novel thyroxine formulations: a further step toward precision medicine

Virili, C., Trimboli, P., & Centanni, M. (2019) · Endocrine · doi:10.1007/s12020-019-02049-x · Cited by 41 · see citing works

Pharmacokinetics and comparative bioavailability of a levothyroxine sodium oral solution and soft capsule

Tanguay, M., Girard, J., Scarsi, C., Mautone, G., & Larouche, R. (2019) · Clinical Pharmacology in Drug Development · doi:10.1002/cpdd.608 · Cited by 33 · see citing works

Treatment pattern and frequency of serum TSH measurement in users of different levothyroxine formulations: a population-based study during the years 2009-2015

Ferrara, R., Ientile, V., Arcoraci, V., Ferrajolo, C., Piccinni, C., Fontana, A., Benvenga, S., & Trifirò, G. (2017) · Endocrine · doi:10.1007/s12020-017-1242-4 · Cited by 23 · see citing works

Levothyroxine sodium pentahydrate tablets – formulation considerations

Kaur, N., & Suryanarayanan, R. (2021) · Journal of Pharmaceutical Sciences · doi:10.1016/j.xphs.2021.08.006 · Cited by 19 · see citing works

Improvements in quality of life and thyroid parameters in hypothyroid patients on ethanol-free formula of liquid levothyroxine therapy in comparison to tablet LT4 form: an observational study

Bornikowska, K., Gietka-Czernel, M., Raczkiewicz, D., Glinicki, P., & Zgliczyński, W. (2021) · Journal of Clinical Medicine · doi:10.3390/jcm10225233 · Cited by 17 · see citing works

Expert opinion on liquid L-thyroxine usage in hypothyroid patients and new liquid thyroxine formulation — Tirosint SOL [Opinia ekspertów dotycząca stosowania płynnej postaci lewotyroksyny oraz nowego preparatu Tirosint SOL u chorych na niedoczynność tarczycy]

Gietka-Czernel, M., Hubalewska-Dydejczyk, A., Kos-Kudła, B., Lewiński, A., Ruchała, M., Syrenicz, A., & Zgliczyński, W. (2020) · Endokrynologia Polska · doi:10.5603/ep.a2020.0065 · Cited by 13 · see citing works

Therapeutic efficacy and patient compliance of levothyroxine liquid and softgel formulations taken with meals: a systematic review.

Oteri, V., Volpe, S., Lopes, M., Sceusa, G., Tumminia, A., Belfiore, A., Frasca, F., & Gullo, D. (2024) · Endocrine · doi:10.1007/s12020-024-04016-7 · Cited by 9 · see citing works

Switching from the tablet to the powder formulation of levothyroxine corrects severe hypothyroidism in a patient with lactose intolerance

Jojima, T., Shinzawa, T., Ohira, E., Sakurai, S., Tomaru, T., Iijima, T., Kogai, T., Usui, I., & Aso, Y. (2022) · Endocrine Journal · doi:10.1507/endocrj.ej21-0656 · Cited by 6 · see citing works

Funkcionalna hrana namijenjena prehrani osoba s intolerancijom na laktozu

Jozinović, K. (2014)

Intolerancija na laktozu

Mijić, D. (2015)

Lactose-poor milk in adult lactose intolerance.

Nagy, L., Mózsik, G., Garamszegi, M., et al. (1983) · PubMed · Cited by 3 · see citing works

Lactose and Milk Intolerance: Clinical Implications

Bayless, T. M., Rothfeld, B., Massa, C., et al. (1975) · New England Journal of Medicine · doi:10.1056/nejm197505292922205 · Cited by 161 · see citing works

Correlation of lactose maldigestion, lactose intolerance, and milk intolerance

Johnson, A., Semenya, J., Buchowski, M. S., et al. (1993) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/57.3.399 · Cited by 114 · see citing works