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Pharmacokinetics and Clinical Implications of Two Non-Tablet Oral Formulations of L-Thyroxine in Patients with Hypothyroidism

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Non-inferiority of liquid thyroxine in comparison to tablets formulation in the treatment of children with congenital hypothyroidism

Tzifi, F., Iliadi, A. C., Voutetakis, A., Platis, D., Girginoudis, P., & Kanaka‐Gantenbein, C. (2021) · Journal of Pediatric Endocrinology and Metabolism · doi:10.1515/jpem-2021-0458 · Cited by 9 · see citing works

Intestinal absorption and buccal absorption of liquid levothyroxine

Benvenga, S., & Di Bari, F. (2017) · Endocrine · doi:10.1007/s12020-017-1250-4 · Cited by 8 · see citing works

A Case of Hashimoto’s Thyroiditis with Multiple Drug Resistance and High Expression of Efflux Transporters

Yoshida, T., Nakayama, A., Tamura, A., Higuchi, S., Sakuma, I., Nagano, H., Felizola, S. J. A., Hashimoto, N., Takemoto, M., Tatsuno, I., et al. (2019) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/clinem/dgz073 · Cited by 8 · see citing works

The impact of proton pump inhibitors on levothyroxine absorption: The good, the bad and the ugly

Guzmán-Prado, Y., Vita, R., & Samson, O. (2020) · European Journal of Internal Medicine · doi:10.1016/j.ejim.2020.02.020 · Cited by 7 · see citing works

Liquid levothyroxine improves thyroid control in patients with different hypothyroidism aetiology and variable adherence — case series and review

Ruchała, M., Bossowski, A. T., Brzózka, M. M., Gietka‐Czernel, M., Hubalewska–Dydejczyk, A., Kos‐Kudła, B., Lewiñski, A., Syrenicz, A., & Zgliczyński, W. (2022) · Endokrynologia Polska · doi:10.5603/ep.a2022.0078 · Cited by 7 · see citing works

Treatment of Hypothyroidism

Jonklaas, J. (2019) · Springer eBooks · doi:10.1007/978-3-319-72102-6_19 · Cited by 6 · see citing works

Lactose intolerance and levothyroxine malabsorption: a review of the literature and report of a series of patients treated with liquid L-T4 without lactose

Ferrari, S. M., Patrizio, A., Mazzi, V., Ragusa, F., Botrini, C., Elia, G., Balestri, E., Barozzi, E., Rugani, L., Bracchitta, F., et al. (2024) · Frontiers in Endocrinology · doi:10.3389/fendo.2024.1386510 · Cited by 5 · see citing works

Thyroid hormone replacement therapy in dialysis/renal insufficiency patients

Zhao, X., Liu, F., Yuan, S., Wang, F., Li, C., Guo, C., & Zhao, J. (2025) · Frontiers in Endocrinology · doi:10.3389/fendo.2025.1540802 · Cited by 5 · see citing works

Liquid L-T4 therapy in hypothyroid patients with gastric diseases, an observational study

Fallahi, P., Ragusa, F., Patrizio, A., Mazzi, V., Botrini, C., Elia, G., Balestri, E., Barozzi, E., Rugani, L., Palmisano, E., et al. (2024) · Frontiers in Endocrinology · doi:10.3389/fendo.2024.1386629 · Cited by 4 · see citing works

Levothyroxine personalized treatment: is it still a dream?

Cappelli, C., Gatta, E., & Ippolito, S. (2024) · Frontiers in Endocrinology · doi:10.3389/fendo.2023.1334292 · Cited by 4 · see citing works

Proton Pump Inhibitors Do Not Affect the Bioavailability of a Novel Liquid Formulation of Levothyroxine

Yue, C. S., Scarsi, C., Bettazzi, E., Mautone, G., Celi, F. S., & Ducharme, M. P. (2024) · Endocrine Practice · doi:10.1016/j.eprac.2024.03.388 · Cited by 4 · see citing works

Evaluating Thyroid Function Tests in Patients with Kidney Disease

Praw, S. S., Way, J. S. A., & Weiss, R. (2019) · Springer eBooks · doi:10.1007/978-3-319-97765-2_7 · Cited by 4 · see citing works

Schilddrüsenhormone – von der Kristallstruktur über die Aktivität zur Reaktivität

Schweizer, U., & Steegborn, C. (2015) · Angewandte Chemie · doi:10.1002/ange.201506919 · Cited by 3 · see citing works

Comparative Bioavailability of a Novel Solution and a Tablet Formulation of Levothyroxine

Vandse, S., Psarrakis, Y., Washington, K., & Baron, M. A. (2023) · Clinical Pharmacology in Drug Development · doi:10.1002/cpdd.1233 · Cited by 3 · see citing works

Efficacy and safety of postoperative levothyroxine sodium tablets for improving serum thyroid hormone levels and tumor marker levels in patients with thyroid tumors

Hao, D., Tian, L., He, H., Zhu, C., Guo, L., Zhang, K., & Zhang, J. (2023) · European Journal of Translational Myology · doi:10.4081/ejtm.2023.11582 · Cited by 3 · see citing works

Levothyroxine-induced serum free thyroxine response following radioactive iodine administration in patients thyroidectomized for differentiated thyroid cancer: A randomized controlled trial

Marina, M., Maglietta, G., Filpo, G. D., Aloe, R., Gnocchi, C., Iezzi, E., Caminiti, C., & Ceresini, G. (2022) · Endocrine · doi:10.1007/s12020-022-03110-y · Cited by 3 · see citing works

Interference or Noninterference Between Soy and Levothyroxine: That Is the Question. A Narrative Review of Literature

Gatta, E., Maltese, V., Cavadini, M., Anelli, V., Bambini, F., Buoso, C., Facondo, P., Pirola, I., Delbarba, A., & Cappelli, C. (2023) · Endocrine Practice · doi:10.1016/j.eprac.2023.08.009 · Cited by 2 · see citing works

Persistent Hypothyroid Symptoms Despite Adequate Thyroid Hormone Replacement

McDermott, M. T. (2019) · Springer eBooks · doi:10.1007/978-3-030-22720-3_23 · Cited by 2 · see citing works

Effect of morning versus night-time administration of proton pump inhibitor (pantoprazole) on thyroid function test in levothyroxine-treated primary hypothyroidism: a prospective cross-over study

Awasthi, A., Chakraborty, P. P., Agrawal, N., Sinha, A., Pandey, A. K., & Maiti, A. (2023) · Thyroid Research · doi:10.1186/s13044-023-00156-6 · Cited by 3 · see citing works

Nuevas formulaciones de levotiroxina en el tratamiento del hipotiroidismo

Iglesias, P. (2023) · Endocrinología Diabetes y Nutrición · doi:10.1016/j.endinu.2023.11.001 · Cited by 2 · see citing works

Switching from Natural Desiccated Thyroid to a Liquid Formulation of Levothyroxine for Hypothyroidism

Khoshaba, L., & Patarkatsi, L. (2023) · Case Reports in Endocrinology · doi:10.1155/2023/4252894 · Cited by 2 · see citing works

Drug forms of levothyroxine. Is there room for innovation in hypothyroidism treatment?

Kolpakova, E. A., Voznesenskaya, А. А., Викторовна, Ф. Н., & Troshina, E. A. (2023) · Clinical and experimental thyroidology · doi:10.14341/ket12759 · Cited by 1 · see citing works

Comparison of tablet versus liquid ethanol-free Levothyroxine in thyroidectomised patients

Croce, L., Chytiris, S., Teliti, M., Bertini, J., Pizzuto, L., Molin, M. D., Limiroli, M., Calì, B., Magri, F., & Rotondi, M. (2025) · Endocrine · doi:10.1007/s12020-025-04375-9 · Cited by 1 · see citing works

Comparative Study Between the Short-Term Effects of Replacement Therapy with Liquid and Tablet Formulations of Levothyroxine on Insulin Resistance Markers in Recently Thyroidectomized Female Patients

Baratta, F., Moscucci, F., Bocale, R., Savoia, C., Cocomello, N., Lospinuso, I., Ettorre, E., Desideri, G., & Pontecorvi, A. (2025) · Metabolites · doi:10.3390/metabo15080547 · Cited by 1 · see citing works

A Phase 2 Study of XP-8121: Once-Weekly Subcutaneous Levothyroxine Sodium for the Treatment of Hypothyroidism in Adults

Conoscenti, V., Huang, R., Rudisill, D., Fitch, R., Broyles, F. E., Ettleson, M. D., & Bianco, A. C. (2026) · Thyroid · doi:10.1177/10507256261454211 · Cited by 1 · see citing works

Importance of Thyroid Hormone Replacement Therapy in Patients with Medullary Thyroid Cancer

Jonklaas, J. (2016) · Springer eBooks · doi:10.1007/978-3-319-39412-1_13 · Cited by 1 · see citing works

Thyroid Hormone Homeostasis in Weight Loss and Implications for Bariatric Surgery

Sweeney, L. B., Campos, G. M., & Celi, F. S. (2016) · Elsevier eBooks · doi:10.1016/b978-0-12-804011-9.00047-9

Therapy Resistant Hypothyroidism

Topaloğlu, O., & Çakır, B. (2018) · Ankara Medical Journal · doi:10.17098/amj.435289

C’è un problema con la tiroide? Attenzione ai farmaci!

Trimarchi, F., & Ruggeri, R. M. (2020) · L Endocrinologo · doi:10.1007/s40619-020-00719-x

Essentials of Thyroid Hormone Treatment in Differentiated Thyroid Cancer

Aydoğan, B. İ., & Gürsoy, A. (2021) · Nuclear Medicine Seminars · doi:10.4274/nts.galenos.2021.0002

Maladies générales, médicaments et fonction thyroïdienne

Balavoine, A.-S. (2022) · Elsevier eBooks · doi:10.1016/b978-2-294-77583-3.00022-8

Deprescribing in Patients of Hypothyroidism Results in Better Health Outcome: A Case Series

Mishra, P., & Bhargava, S. (2023) · Journal of Pharmaceutical Care · doi:10.18502/jpc.v10i4.11589

New formulations of levothyroxine in the treatment of hypothyroidism

Iglesias, P. (2024) · Endocrinología Diabetes y Nutrición (English ed ) · doi:10.1016/j.endien.2024.03.009

Food-Drug Interactions: Navigating the Complex Relationship

Ewis, D. K., & El-Sayed, O. S. (2025) · Nutritional neurosciences · doi:10.1007/978-981-95-1983-5_14

Formulations for the Replacement Therapy of Hypothyroidism: State of the Art and Perspectives

Lugaresi, M., & Fugazzola, L. (2025) · Springer eBooks · doi:10.1007/978-3-032-01700-0_13

Additional file 1 of Effect of morning versus night-time administration of proton pump inhibitor (pantoprazole) on thyroid function test in levothyroxine-treated primary hypothyroidism: a prospective cross-over study

Awasthi, A., Chakraborty, P. P., Agrawal, N., Sinha, A., Pandey, A. K., & Maiti, A. (2023) · Figshare · doi:10.6084/m9.figshare.23273466

Liquid or soft-gel levothyroxine vs tablet levothyroxine in athyreotic adults after total thyroidectomy: Systematic review and meta-analysis

Farhan, M., Patel, T., Obais, M. A.-H. N., Taslimi, H., Hanif, M., Khalid, K., Qaqour, A., Waisi, J., Khalid, H., Husain, A. H. A. A., et al. (2026) · World Journal of Clinical Cases · doi:10.12998/wjcc.v14.i16.119700

Weight-based levothyroxine dosing and long-term cardiovascular, bone, and mortality outcomes in older adults: an emulated target trial using UK primary care data

Holley, M., Wilkes, S., Moss, E. D., Maxwell, I., Dew, R., & Razvi, S. (2026) · The Lancet Primary Care · doi:10.1016/j.lanprc.2026.100194

PSAT366 Liquid L-thyroxine (L-T4) Formulation Normalizes TSH in Hypothyroid Patients Treated with Tablets L-T4

Antonelli, A., Ferrari, S. M., Fallahi, P., Elia, G., Ragusa, F., Paparo, S. R., Balestri, E., Botrini, C., Patrizio, A., & Mazzi, V. (2022) · Journal of the Endocrine Society · doi:10.1210/jendso/bvac150.1740

Tablet levothyroxine (L-T4) malabsorption induced by proton pump inhibitor: a problem that was solved by switching to L-T4 in soft gel capsule

Vita, R., & Benvenga, S. (2014) · Endocrine Practice · doi:10.4158/ep13316.cr · Cited by 60 · see citing works

RF23 | PSAT365 An Open-Label Therapeutic Efficacy Study of Tirosint (Levothyroxine Sodium) Capsules in Thyroidectomized Patients Taking Proton Pump Inhibitors

Sachmechi, I., Burman, K. D., Mautone, G., Lanzi, G., Moriarty, P. L., Scarsi, C., & Wartofsky, L. (2022) · Journal of the Endocrine Society · doi:10.1210/jendso/bvac150.1777

Efficacy of Levothyroxine Sodium Soft Gelatin Capsules in Thyroidectomized Patients Taking Proton Pump Inhibitors: An Open-Label Study

Sachmechi, I., Lucas, K. J., Stonesifer, L. D., Ansley, J. F., Sack, P., Celi, F. S., Scarsi, C., Lanzi, G., Wartofsky, L., & Burman, K. D. (2023) · Thyroid · doi:10.1089/thy.2023.0382 · Cited by 7 · see citing works

The effect on serum tsh levels in patients in treatment with proton pump inhibitors after the switch from oral L-T4 tablet to a liquid L-T4 formulation

Fallahi, P., Martina, F. S., Elia, G., Ragusa, F., Paparo, S. R., Mazzi, V., & Antonelli, A. (2022) · Endocrine Abstracts · doi:10.1530/endoabs.84.ps2-06-52