The Role of SORL1 in Alzheimer’s Disease

The neuronal sortilin-related receptor SORL1 is genetically associated with Alzheimer disease

Rogaeva, E., Meng, Y., Lee, J. H., Gu, Y., Kawarai, T., Zou, F., Katayama, T., Baldwin, C. T., Cheng, R., Hasegawa, H., et al. (2007) · Nature Genetics · doi:10.1038/ng1943 · Cited by 1,167 · see citing works

Neuronal sorting protein-related receptor sorLA/LR11 regulates processing of the amyloid precursor protein

Andersen, O. M., Reiche, J., Schmidt, V., Gotthardt, M., Spoelgen, R., Behlke, J., von Arnim, C. A. F., Breiderhoff, T., Jansen, P., Wu, X., et al. (2005) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0503689102 · Cited by 655 · see citing works

The sorting receptor for yeast vacuolar carboxypeptidase Y is encoded by the VPS10 gene

Marcusson, E. G., Horazdovsky, B. F., Cereghino, J. L., Gharakhanian, E., & Emr, S. D. (1994) · Cell · doi:10.1016/0092-8674(94)90219-4 · Cited by 509 · see citing works

Depletion of GGA3 Stabilizes BACE and Enhances β-Secretase Activity

Tesco, G., Koh, Y. H., Kang, E. L., Cameron, A. N., Das, S., Sena-Esteves, M., Hiltunen, M., Yang, S.-H., Zhong, Z., Shen, Y., et al. (2007) · Neuron · doi:10.1016/j.neuron.2007.05.012 · Cited by 337 · see citing works

Loss of apolipoprotein E receptor LR11 in Alzheimer disease

Scherzer, C. R., Offe, K., Gearing, M., Rees, H. D., Fang, G., Heilman, C. J., Schaller, C., Bujo, H., Levey, A. I., & Lah, J. J. (2004) · Archives of Neurology · doi:10.1001/archneur.61.8.1200 · Cited by 316 · see citing works

The Lipoprotein Receptor LR11 Regulates Amyloid β Production and Amyloid Precursor Protein Traffic in Endosomal Compartments

Offe, K., Dodson, S. E., Shoemaker, J. T., Fritz, J. J., Gearing, M., Levey, A. I., & Lah, J. J. (2006) · Journal of Neuroscience · doi:10.1523/jneurosci.4946-05.2006 · Cited by 279 · see citing works

Retromer Binds the FANSHY Sorting Motif in SorLA to Regulate Amyloid Precursor Protein Sorting and Processing

Fjorback, A. W., Seaman, M. N. J., Gustafsen, C., Mehmedbašić, A., Gokool, S., Wu, C., Militz, D., Schmidt, V., Madsen, P., Nyengaard, J. R., et al. (2012) · Journal of Neuroscience · doi:10.1523/jneurosci.2272-11.2012 · Cited by 253 · see citing works

Molecular Characterization of a Novel Human Hybrid-type Receptor That Binds the α2-Macroglobulin Receptor-associated Protein

Jacobsen, L., Madsen, P., Moestrup, S. K., Lund, A. H., Tommerup, N., Nykjær, A., Sottrup-Jensen, L., Gliemann, J., & Petersen, C. M. (1996) · Journal of Biological Chemistry · doi:10.1074/jbc.271.49.31379 · Cited by 253 · see citing works

Identification of a novel conserved sorting motif required for retromer-mediated endosome-to-TGN retrieval

Seaman, M. N. J. (2007) · Journal of Cell Science · doi:10.1242/jcs.009654 · Cited by 240 · see citing works

Epidemiology and Etiology of Alzheimer’s disease: From Genetic to Non- Genetic Factors

Jiang, T., Yu, J., Tian, Y., & Tan, L. (2013) · Current Alzheimer Research · doi:10.2174/15672050113109990155 · Cited by 224 · see citing works

Elements of Neural Adhesion Molecules and a Yeast Vacuolar Protein Sorting Receptor Are Present in a Novel Mammalian Low Density Lipoprotein Receptor Family Member

Yamazaki, H., Bujo, H., Kusunoki, J., Seimiya, K., Kanaki, T., Morisaki, N., Schneider, W. J., & Saitō, Y. (1996) · Journal of Biological Chemistry · doi:10.1074/jbc.271.40.24761 · Cited by 204 · see citing works

SORL1 Is Genetically Associated with Late-Onset Alzheimer’s Disease in Japanese, Koreans and Caucasians

Miyashita, A., Koike, A., Jun, G., Wang, L.-S., Takahashi, S., Matsubara, E., Kawarabayashi, T., Shoji, M., Tomita, N., Arai, H., et al. (2013) · PLoS ONE · doi:10.1371/journal.pone.0058618 · Cited by 196 · see citing works

Sorting by the Cytoplasmic Domain of the Amyloid Precursor Protein Binding Receptor SorLA

Nielsen, M. S., Gustafsen, C., Madsen, P., Nyengaard, J. R., Hermey, G., Bakke, O., Mari, M. C., Schu, P. V., Pohlmann, R., Dennes, A., et al. (2007) · Molecular and Cellular Biology · doi:10.1128/mcb.00815-07 · Cited by 188 · see citing works

SorLA/LR11 regulates processing of amyloid precursor protein via interaction with adaptors GGA and PACS-1

Schmidt, V., Sporbert, A., Rohe, M., Reimer, T., Rehm, A., Andersen, O. M., & Willnow, T. E. (2007) · Journal of Biological Chemistry · doi:10.1074/jbc.m705073200 · Cited by 181 · see citing works

Lysosomal Sorting of Amyloid-β by the SORLA Receptor Is Impaired by a Familial Alzheimer’s Disease Mutation

Çağlayan, Ş., Takagi‐Niidome, S., Liao, F., Carlo, A.-S., Schmidt, V., Burgert, T., Kitago, Y., Füchtbauer, E., Füchtbauer, A. C., Holtzman, D. M., et al. (2014) · Science Translational Medicine · doi:10.1126/scitranslmed.3007747 · Cited by 169 · see citing works

An intronic ncRNA-dependent regulation of SORL1 expression affecting Aβ formation is upregulated in post-mortem Alzheimer's disease brain samples

Ciarlo, E., Massone, S., Penna, I., Nizzari, M., Gigoni, A., Dieci, G., Russo, C., Florio, T., Cancedda, R., & Pagano, A. (2012) · Disease Models & Mechanisms · doi:10.1242/dmm.009761 · Cited by 169 · see citing works

Meta-analysis of the Association Between Variants in SORL1 and Alzheimer Disease

Reitz, C. (2011) · Archives of Neurology · doi:10.1001/archneurol.2010.346 · Cited by 162 · see citing works

LR11/SorLA Expression Is Reduced in Sporadic Alzheimer Disease but not in Familial Alzheimer Disease

Dodson, S. E., Gearing, M., Lippa, C. F., Montine, T. J., Levey, A. I., & Lah, J. J. (2006) · Journal of Neuropathology & Experimental Neurology · doi:10.1097/01.jnen.0000228205.19915.20 · Cited by 154 · see citing works

The Association Between Genetic Variants in SORL1 and Alzheimer Disease in an Urban, Multiethnic, Community-Based Cohort

Lee, J. H., Cheng, R., Schupf, N., Manly, J. J., Lantigua, R., Stern, Y., Rogaeva, E. A., Wakutani, Y., Farrer, L. A., George‐Hyslop, P. S., et al. (2007) · Archives of Neurology · doi:10.1001/archneur.64.4.501 · Cited by 143 · see citing works

Brain-Derived Neurotrophic Factor Reduces Amyloidogenic Processing through Control of SORLA Gene Expression

Rohe, M., Synowitz, M., Glaß, R., Paul, S. M., Nykjær, A., & Willnow, T. E. (2009) · Journal of Neuroscience · doi:10.1523/jneurosci.3960-09.2009 · Cited by 122 · see citing works

Sorting receptor SORLA – a trafficking path to avoid Alzheimer disease

Willnow, T. E., & Andersen, O. M. (2013) · Journal of Cell Science · doi:10.1242/jcs.125393 · Cited by 121 · see citing works

Omega-3 Fatty Acid Docosahexaenoic Acid Increases SorLA/LR11, a Sorting Protein with Reduced Expression in Sporadic Alzheimer's Disease (AD): Relevance to AD Prevention

Ma, Q., Teter, B., Ubeda, O. J., Morihara, T., Dhoot, D. S., Nyby, M. D., Tuck, M. L., Frautschy, S. A., & Cole, G. M. (2007) · Journal of Neuroscience · doi:10.1523/jneurosci.3593-07.2007 · Cited by 115 · see citing works

Sortilin, SorCS1b, and SorLA Vps10p sorting receptors, are novel γ-secretase substrates

Nyborg, A. C., Ladd, T. B., Zwizinski, C. W., Lah, J. J., & Golde, T. E. (2006) · Molecular Neurodegeneration · doi:10.1186/1750-1326-1-3 · Cited by 98 · see citing works

LR11, a Mosaic LDL Receptor Family Member, Mediates the Uptake of ApoE-Rich Lipoproteins In Vitro

Taira, K., Bujo, H., Hirayama, S., Yamazaki, H., Kanaki, T., Takahashi, K., Ishii, I., Miida, T., Schneider, W. J., & Saitō, Y. (2001) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/hq0901.094500 · Cited by 97 · see citing works

Neuronal LR11/sorLA expression is reduced in mild cognitive impairment

Sager, K. L., Wuu, J., Leurgans, S. E., Rees, H. D., Gearing, M., Mufson, E. J., Levey, A. I., & Lah, J. J. (2007) · Annals of Neurology · doi:10.1002/ana.21190 · Cited by 96 · see citing works

Effects of DHA- Rich n-3 Fatty Acid Supplementation on Gene Expression in Blood Mononuclear Leukocytes: The OmegAD Study

Vedin, I., Cederholm, T., Freund‐Levi, Y., Basun, H., Garlind, A., Irving, G. F., Eriksdotter, M., Wahlund, L., Dahlman, I. A., & Palmblad, J. E. W. (2012) · PLoS ONE · doi:10.1371/journal.pone.0035425 · Cited by 92 · see citing works

A PACS‐1, GGA3 and CK2 complex regulates CI‐MPR trafficking

Scott, G. K., Hao, F., Thomas, L., Medigeshi, G. R., & Thomas, G. (2006) · The EMBO Journal · doi:10.1038/sj.emboj.7601336 · Cited by 89 · see citing works

Reduction of SorLA/LR11, a Sorting Protein Limiting β-Amyloid Production, in Alzheimer Disease Cerebrospinal Fluid

Ma, Q., Galasko, D. R., Ringman, J. M., Vinters, H. V., Edland, S. D., Pomakian, J., Ubeda, O. J., Rosario, E. R., Teter, B., Frautschy, S. A., et al. (2009) · Archives of Neurology · doi:10.1001/archneurol.2009.22 · Cited by 86 · see citing works

Association between SORL1 and Alzheimer's disease in a genome-wide study

Meng, Y., Lee, J. H., Cheng, R., George‐Hyslop, P. S., Mayeux, R. P., & Farrer, L. A. (2007) · Neuroreport · doi:10.1097/wnr.0b013e3282f13e7a · Cited by 86 · see citing works

SorLA Signaling by Regulated Intramembrane Proteolysis

Böhm, C., Seibel, N. M., Henkel, B., Steiner, H., Haass, C., & Hampe, W. (2006) · Journal of Biological Chemistry · doi:10.1074/jbc.m601660200 · Cited by 83 · see citing works

SORL1 variants and risk of late-onset Alzheimer’s disease

Li, Y., Rowland, C. M., Catanese, J. J., Morris, J. C., Lovestone, S., O’Donovan, M. C., Goate, A., Owen, M. J., Williams, J. H., & Grupe, A. (2007) · Neurobiology of Disease · doi:10.1016/j.nbd.2007.09.001 · Cited by 79 · see citing works

Neuronal localization of a novel mosaic apolipoprotein E receptor, LR11, in rat and human brain

Motoi, Y., Aizawa, T., Haga, S., Nakamura, S., Namba, Y., & Ikeda, K. (1999) · Brain Research · doi:10.1016/s0006-8993(99)01542-5 · Cited by 78 · see citing works

Quantitative modelling of amyloidogenic processing and its influence by SORLA in Alzheimer's disease

Schmidt, V., Baum, K., Lao, A., Rateitschak, K., Schmitz, Y., Teichmann, A., Wiesner, B., Petersen, C. M., Nykjaer, A., Wolf, J., et al. (2012) · The EMBO Journal · doi:10.1038/emboj.2011.352 · Cited by 75 · see citing works

Genetic loci associated with Alzheimer's disease and cerebrospinal fluid biomarkers in a Finnish case–control cohort

Elias-Sonnenschein, L. S., Helisalmi, S., Natunen, T., Hall, A., Paajanen, T., Herukka, S.-K., Laitinen, M., Remes, A. M., Koivisto, A. M., Mattila, K. M., et al. (2013) · PLoS ONE · doi:10.1371/journal.pone.0059676 · Cited by 70 · see citing works

SORL1 haplotypes modulate risk of Alzheimer's disease in Chinese

Tan, E., Lee, J., Chen, C., Teo, Y. Y., Zhao, Y., & Lee, W. L. (2007) · Neurobiology of Aging · doi:10.1016/j.neurobiolaging.2007.10.013 · Cited by 69 · see citing works

SORL1 and SIRT1 mRNA expression and promoter methylation levels in aging and Alzheimer’s Disease

Furuya, T. K., Silva, P. N., Payão, S. L. M., Rasmussen, L. T., de Lábio, R. W., Bertolucci, P. H. F., Braga, I. L. S., Chen, E., Turecki, G., Mechawar, N., et al. (2012) · Neurochemistry International · doi:10.1016/j.neuint.2012.07.014 · Cited by 61 · see citing works

Association of distinct variants in SORL1 with cerebrovascular and neurodegenerative changes related to Alzheimer disease

Cuenco, K. T. (2008) · Archives of Neurology · doi:10.1001/archneur.65.12.1640 · Cited by 61 · see citing works

Expression of SORL1 and a novel SORL1 splice variant in normal and Alzheimers disease brain

Grear, K. E., Ling, I.-F., Simpson, J. F., Furman, J. L., Simmons, C. R., Peterson, S. L., Schmitt, F. A., Markesbery, W. R., Liu, Q., Crook, J. E., et al. (2009) · Molecular Neurodegeneration · doi:10.1186/1750-1326-4-46 · Cited by 56 · see citing works

Rho Kinase II Phosphorylation of the Lipoprotein Receptor LR11/SORLA Alters Amyloid-β Production

Herskowitz, J. H., Seyfried, N. T., Gearing, M., Kahn, R., Peng, J., Levey, A. I., & Lah, J. J. (2010) · Journal of Biological Chemistry · doi:10.1074/jbc.m110.167239 · Cited by 55 · see citing works

GGA1-mediated endocytic traffic of LR11/SorLA alters APP intracellular distribution and amyloid-β production

Herskowitz, J. H., Offe, K., Deshpande, A., Kahn, R., Levey, A. I., & Lah, J. J. (2012) · Molecular Biology of the Cell · doi:10.1091/mbc.e12-01-0014 · Cited by 54 · see citing works

SORL1 is genetically associated with Alzheimer disease in a Japanese population

Kimura, R., Yamamoto, M. L., Morihara, T., Akatsu, H., Kudo, T., Kamino, K., & Takeda, M. (2009) · Neuroscience Letters · doi:10.1016/j.neulet.2009.06.014 · Cited by 50 · see citing works

Implication of Sex and SORL1 Variants in Italian Patients With Alzheimer Disease

Cellini, E., Tedde, A., Bagnoli, S., Pradella, S., Piacentini, S., Sorbi, S., & Nacmias, B. (2009) · Archives of Neurology · doi:10.1001/archneurol.2009.101 · Cited by 48 · see citing works

Association of SORL1 gene variants with Alzheimer's disease

Kölsch, H., Jessen, F., Wiltfang, J., Lewczuk, P., Dichgans, M., Teipel, S. J., Kornhuber, J., Frölich, L., Heuser, I., Peters, O., et al. (2009) · Brain Research · doi:10.1016/j.brainres.2009.01.044 · Cited by 47 · see citing works

Genetic Association between SORL1 Polymorphisms and Alzheimer’s Disease in a Japanese Population

Shibata, N., Ohnuma, T., Baba, H., Higashi, S., Nishioka, K., & Arai, H. (2008) · Dementia and Geriatric Cognitive Disorders · doi:10.1159/000149821 · Cited by 43 · see citing works

Decreased expression of GGA3 Protein in Alzheimer's disease frontal cortex and increased co-distribution of BACE with the amyloid precursor protein

Santosa, C., Rasche, S., Barakat, A., Bellingham, S. A., Ho, M., Tan, J., Hill, A. F., Masters, C. L., McLean, C., & Evin, G. M. (2011) · Neurobiology of Disease · doi:10.1016/j.nbd.2011.03.009 · Cited by 41 · see citing works

Impact of SORL1 Single Nucleotide Polymorphisms on Alzheimer’s Disease Cerebrospinal Fluid Markers

Alexopoulos, P., Guo, L., Kratzer, M., Westerteicher, C., Kurz, A., Perneczky, R., & Initiative, A. D. N. (2011) · Dementia and Geriatric Cognitive Disorders · doi:10.1159/000332017 · Cited by 41 · see citing works

Influence of SORL1 gene variants: Association with CSF amyloid-β products in probable Alzheimer's disease

Kölsch, H., Jessen, F., Wiltfang, J., Lewczuk, P., Dichgans, M., Kornhuber, J., Frölich, L., Heuser, I., Peters, O., Schulz, J. B., et al. (2008) · Neuroscience Letters · doi:10.1016/j.neulet.2008.05.049 · Cited by 40 · see citing works

GGA Autoinhibition Revisited

Cramer, J. F., Gustafsen, C., Behrens, M. A., Oliveira, C. L. P., Pedersen, J. S., Madsen, P., Petersen, C. M., & Thirup, S. (2009) · Traffic · doi:10.1111/j.1600-0854.2009.01017.x · Cited by 39 · see citing works

A Study of the SORL1 Gene in Alzheimer's Disease and Cognitive Function

Liu, F., Ikram, M. A., Janssens, A. C. J. W., Schuur, M., de Koning, I., Isaacs, A. J., Struchalin, M. V., Uitterlinden, A. G., den Dunnen, J. T., Sleegers, K., et al. (2009) · Journal of Alzheimer s Disease · doi:10.3233/jad-2009-1137 · Cited by 38 · see citing works

Increased Levels of Soluble LR11 in Cerebrospinal Fluid of Patients with Alzheimer Disease

Ikeuchi, T., Hirayama, S., Miida, T., Fukamachi, I., Tokutake, T., Ebinuma, H., Takubo, K., Kaneko, H., Kasuga, K., Kakita, A., et al. (2010) · Dementia and Geriatric Cognitive Disorders · doi:10.1159/000315539 · Cited by 38 · see citing works

Amyloid-β-Related Genes SORL1 and ACE are Genetically Associated With Risk for Late-onset Alzheimer Disease in the Chinese Population

Ning, M., Yang, Y., Zhang, Z., Chen, Z., Zhao, T., Zhang, D., Zhou, D., Xu, J., Liu, Z., Wang, Y., et al. (2010) · Alzheimer Disease & Associated Disorders · doi:10.1097/wad.0b013e3181e6a575 · Cited by 37 · see citing works

SORL1 is Genetically Associated with Neuropathologically Characterized Late-Onset Alzheimer's Disease

Wen, Y., Initiative, J. A. D. N., Miyashita, A., Kitamura, N., Tsukie, T., Saito, Y., Hatsuta, H., Murayama, S., Kakita, A., Takahashi, H., et al. (2013) · Journal of Alzheimer s Disease · doi:10.3233/jad-122395 · Cited by 37 · see citing works

Inhibitors of Rho‐kinase modulate amyloid‐β (Aβ) secretion but lack selectivity for Aβ42

Leuchtenberger, S., Kummer, M. P., Kukar, T. L., Czirr, E., Teusch, N. E., Sagi, S. A., Berdeaux, R., Pietrzik, C. U., Ladd, T. B., Golde, T. E., et al. (2005) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.2005.03553.x · Cited by 30 · see citing works

An Updated Meta-Analysis of the Association between SORL1 Variants and the Risk for Sporadic Alzheimer's Disease

Jin, C., Liu, X., Zhang, F., Wu, Y., Yuan, J., Zhu, J., Zhang, F., Wang, G., & Cheng, Z. (2013) · Journal of Alzheimer s Disease · doi:10.3233/jad-130533 · Cited by 28 · see citing works

SORL1 genetic variants and cerebrospinal fluid biomarkers of Alzheimer’s disease

Guo, L., Westerteicher, C., Wang, X., Kratzer, M., Tsolakidou, A. F., Jiang, M., Grimmer, T., Laws, S. M., Alexopoulos, P., Bujo, H., et al. (2012) · European Archives of Psychiatry and Clinical Neuroscience · doi:10.1007/s00406-012-0295-x · Cited by 28 · see citing works

Single-nucleotide polymorphisms of GSK3B, GAB2 and SORL1 in late-onset Alzheimer's disease: interactions with the APOE genotype

Izzo, G., Forlenza, O. V., dos Santos, B., Bertolucci, P. H. F., Ojopi, E. P. B., Gattaz, W. F., & Kerr, D. S. (2013) · Clinics · doi:10.6061/clinics/2013(02)rc01 · Cited by 26 · see citing works

Protein kinase C and rho activated coiled coil protein kinase 2 (ROCK2) modulate Alzheimer's APP metabolism and phosphorylation of the Vps10-domain protein, SorL1

Lane, R. F., Small, S. A., Gatson, J. W., Ehrlich, M. E., & Gandy, S. (2010) · Molecular Neurodegeneration · doi:10.1186/1750-1326-5-62 · Cited by 21 · see citing works

β‐Site amyloid precursor protein–cleaving enzyme 1 activity is related to cerebrospinal fluid concentrations of sortilin‐related receptor with A‐type repeats, soluble amyloid precursor protein, and tau

Tsolakidou, A. F., Alexopoulos, P., Guo, L., Grimmer, T., Westerteicher, C., Kratzer, M., Jiang, M., Bujo, H., Roselli, F., Leante, M. R., et al. (2012) · Alzheimer s & Dementia · doi:10.1016/j.jalz.2012.01.015 · Cited by 19 · see citing works

SorLA Deficiency Dissects Amyloid Pathology from Tau and Cholinergic Neurodegeneration in a Mouse Model of Alzheimer's Disease

Capsoni, S., Carlo, A.-S., Vignone, D., Amato, G., Criscuolo, C., Willnow, T. E., & Cattaneo, A. (2012) · Journal of Alzheimer s Disease · doi:10.3233/jad-2012-121399 · Cited by 17 · see citing works

Association between the SORL1 rs2070045 polymorphism and late-onset Alzheimer's disease: Interaction with the ApoE genotype in the Chinese Han population

Xue, X., Zhang, M., Lin, Y., Xu, E., & Jia, J. (2013) · Neuroscience Letters · doi:10.1016/j.neulet.2013.11.042 · Cited by 15 · see citing works

Effects of SORL1 Gene on Alzheimer's Disease. Focus on Gender, Neuropsychiatric Symptoms and Pro-Inflammatory Cytokines

Olgiati, P., Politis, A. M., Albani, D., Rodilossi, S., Polito, L., Zisaki, A., Piperi, C., Liappas, I., Stamouli, E., Mailis, A., et al. (2013) · Current Alzheimer Research · doi:10.2174/1567205011310020005 · Cited by 13 · see citing works

Molecular and cellular mechanisms underlying the pathogenesis of Alzheimer’s disease

Guo, T., Zhang, D., Zeng, Y., Huang, T. Y., Xu, H., & Zhao, Y. (2020) · Molecular Neurodegeneration · doi:10.1186/s13024-020-00391-7 · Cited by 994 · see citing works

Alzheimer’s Disease: An Updated Overview of Its Genetics

Andrade-Guerrero, J., Santiago-Balmaseda, A., Jeronimo-Aguilar, P., Vargas-Rodríguez, I., Cadena-Suárez, A. R., Sánchez-Garibay, C., Pozo-Molina, G., Méndez-Catalá, C. F., Cardenas-Aguayo, M.-D.-C., Diaz-Cintra, S., et al. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms24043754 · Cited by 336 · see citing works

The biological pathways of Alzheimer disease: a review

Calabrò, M., Rinaldi, C., Santoro, G., & Crisafulli, C. (2020) · AIMS neuroscience · doi:10.3934/neuroscience.2021005 · Cited by 271 · see citing works

Questions concerning the role of amyloid-β in the definition, aetiology and diagnosis of Alzheimer’s disease

Morris, G. P., Clark, I. A., & Vissel, B. (2018) · Acta Neuropathologica · doi:10.1007/s00401-018-1918-8 · Cited by 212 · see citing works

Noncoding RNAs in Alzheimer's disease

Idda, M. L., Munk, R. B., Abdelmohsen, K., & Gorospe, M. (2018) · Wiley Interdisciplinary Reviews - RNA · doi:10.1002/wrna.1463 · Cited by 206 · see citing works

The new genetic landscape of Alzheimer’s disease: from amyloid cascade to genetically driven synaptic failure hypothesis?

Dourlen, P., Kilinc, D., Malmanche, N., Chapuis, J., & Lambert, J.-C. (2019) · Acta Neuropathologica · doi:10.1007/s00401-019-02004-0 · Cited by 168 · see citing works

Gene-environment interactions in Alzheimer's disease: A potential path to precision medicine

Eid, A., Mhatre, I., & Richardson, J. R. (2019) · Pharmacology & Therapeutics · doi:10.1016/j.pharmthera.2019.03.005 · Cited by 164 · see citing works

Alzheimer’s disease: How metal ions define β-amyloid function

Kepp, K. P. (2017) · Coordination Chemistry Reviews · doi:10.1016/j.ccr.2017.05.007 · Cited by 151 · see citing works

Prediction of Alzheimer’s disease using blood gene expression data

Lee, T., & Lee, H. (2020) · Scientific Reports · doi:10.1038/s41598-020-60595-1 · Cited by 140 · see citing works

Long Non-Coding RNA (lncRNA) Roles in Cell Biology, Neurodevelopment and Neurological Disorders

Aliperti, V., Skonieczna, J., & Cerase, A. (2021) · Non-Coding RNA · doi:10.3390/ncrna7020036 · Cited by 137 · see citing works

Protective genes and pathways in Alzheimer’s disease: moving towards precision interventions

Seto, M., Weiner, R. L., Dumitrescu, L., & Hohman, T. J. (2021) · Molecular Neurodegeneration · doi:10.1186/s13024-021-00452-5 · Cited by 135 · see citing works

Alzheimer’s disease due to loss of function: A new synthesis of the available data

Kepp, K. P. (2016) · Progress in Neurobiology · doi:10.1016/j.pneurobio.2016.06.004 · Cited by 123 · see citing works

The role of innate immunity in Alzheimer's disease

Ennerfelt, H. E., & Lukens, J. R. (2020) · Immunological Reviews · doi:10.1111/imr.12896 · Cited by 121 · see citing works

Insight into the genetic etiology of Alzheimer's disease: A comprehensive review of the role of rare variants

Hoogmartens, J., Cacace, R., & Broeckhoven, C. V. (2021) · Alzheimer s & Dementia Diagnosis Assessment & Disease Monitoring · doi:10.1002/dad2.12155 · Cited by 101 · see citing works

Alzheimer’s Disease: Etiology, Neuropathology and Pathogenesis

Sheppard, O., & Coleman, M. P. (2020) · Exon Publications eBooks · doi:10.36255/exonpublications.alzheimersdisease.2020.ch1 · Cited by 112 · see citing works

The Role of Selected Bioactive Compounds in the Prevention of Alzheimer’s Disease

Grodzicki, W., & Dziendzikowska, K. (2020) · Antioxidants · doi:10.3390/antiox9030229 · Cited by 102 · see citing works

Cerebral small vessel disease and Alzheimer’s disease

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An optimized quantitative proteomics method establishes the cell type‐resolved mouse brain secretome

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