In vitro antibacterial activity of laboratory grown culture of Spirulina platensis
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The hexane, ethyl acetate, dichloromethane, methanol extracts and spent media (extracellular substances) were tested in vitro for their antibacterial activity for which one Gram-positive bacterium (Staphylococcus aureus) and four Gram-negative bacteria (Escherichia coli, Pseudomonas aeruginosa, Salmonella typhi, and Klebsiella pneumoniae) were used as test organisms. The methanol extract showed more potent activity than other organic extracts, spent medium of the culture exhibited little activity against E. coli only. No inhibitory effect was found against Klebsiella pneumoniae.The broth microdilution assay gave minimum inhibitory concentrations (MIC) values ranging from 1 to 512 μg/ml. The MIC of methanol extract against S. aureus and E. coli were 128 μg/ml and 256 μg/ml, respectively.
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Microbial-modulating activities have been reported in vitro for Spirulina.
“Microbial-modulating activities have been reported in vitro”
From Antioxidant, Immunomodulating, and Microbial‐Modulating Activities of the Sustainable and Ecofriendly <i>Spirulina</i> (2017) · cites this paper as [21]
Spirulina produces extracellular metabolites with antibacterial activity.
“Spirulina produces extracellular metabolites with antibacterial activity (Figure 1) [19–21, 77].”
From Antioxidant, Immunomodulating, and Microbial‐Modulating Activities of the Sustainable and Ecofriendly <i>Spirulina</i> (2017) · cites this paper as [21]
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Targeting cyanobacteria as a novel source of biofuel.
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Spirulina Platensis: A Natural Product with many Biological Properties
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- Authors
- Kaushik, P., & Chauhan, A.
- Affiliations
- Gurukul Kangri Vishwavidyalaya (IN)
- Corresponding author
- Chauhan, Abhishek
- ORCID
- Chauhan, Abhishek
- Venue
- Indian Journal of Microbiology
- Published
- 2008-09
- Volume
- 48
- Issue
- 3
- Pages
- 348-352
- ISSN
- 0046-8991 (ISSN-L)
- 0973-7715
- PMC
- PMC3476771
- OpenAlex
- W2145172529
- Cited by
- 124
- References
- 14
- Citations by year
- 2026: 6 · 2025: 6 · 2024: 9 · 2023: 14 · 2022: 8 · 2021: 9 · 2020: 15 · 2019: 6 · 2018: 5 · 2017: 7 · 2016: 3 · 2015: 6 · 2014: 5 · 2013: 8 · 2012: 4
- FWCI
- 6.03
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Licence
- www.springer.com/tdm (tdm)
- Locations
- Indian Journal of Microbiology (publishedVersion)
- Europe PMC (PubMed Central) (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Agricultural and Biological Sciences › Aquatic Science › Seaweed-derived Bioactive Compounds
- Life Sciences › Agricultural and Biological Sciences › Food Science › Essential Oils and Antimicrobial Activity
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Bacterial biofilms and quorum sensing
- Keywords
- Spirulina platensis, antibacterial activity, methanol extract, spent culture medium, extracellular substances, Staphylococcus aureus, Escherichia coli, Pseudomonas aeruginosa, Salmonella typhi, Klebsiella pneumoniae, minimum inhibitory concentration
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