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Review and Meta-analysis of Couple-Oriented Interventions for Chronic Illness

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Martire, Lynn M., Schulz, Richard, Helgeson, Vicki S., Small, Brent J., Saghafi, Ester M.·2010·Annals of Behavioral Medicine
DOI 10.1007/s12160-010-9216-2PMC PMC4101802
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Abstract

BACKGROUND: Evidence continues to build for the impact of the marital relationship on health as well as the negative impact of illness on the partner. Targeting both patient and partner may enhance the efficacy of psychosocial or behavioral interventions for chronic illness. PURPOSE: The purpose of this report is to present a cross-disease review of the characteristics and findings of studies evaluating couple-oriented interventions for chronic physical illness. METHODS: We conducted a qualitative review of 33 studies and meta-analyses for a subset of 25 studies. RESULTS: Identified studies focused on cancer, arthritis, cardiovascular disease, chronic pain, HIV, and Type 2 diabetes. Couple interventions had significant effects on patient depressive symptoms (d = 0.18, p < 0.01, k = 20), marital functioning (d = 0.17, p < 0.01, k = 18), and pain (d = 0.19, p < 0.01, k = 14) and were more efficacious than either patient psychosocial intervention or usual care. CONCLUSIONS: Couple-oriented interventions have small effects that may be strengthened by targeting partners' influence on patient health behaviors and focusing on couples with high illness-related conflict, low partner support, or low overall marital quality. Directions for future research include assessment of outcomes for both patient and partner, comparison of couple interventions to evidence-based patient interventions, and evaluation of mechanisms of change.

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  1. Borenstein M, Hedges L, Higgins J, Rothstein H. Comprehensive Meta-analysis Version 2. Englewood, NJ: Biostat; 2005.
  2. Nock MK, Janis IB, Wedig MM. Research designs. In: Nezu AM, Nezu CM, eds. Evidence-Based. Outcome Research: A Practical Guide to Conducting Randomized Controlled Trials for Psychosocial Interventions Oxford University Press; 2008:201-218.

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Metadata

Authors
Martire, L. M., Schulz, R., Helgeson, V. S., Small, B. J., & Saghafi, E. M.
Affiliations
  • Pennsylvania State University (US)
  • University of Pittsburgh (US)
  • Carnegie Mellon University (US)
  • University of South Florida (US)
Corresponding author
Martire, Lynn M.
ORCID
Venue
Annals of Behavioral Medicine
Publisher
Oxford University Press (OUP)
Published
2010-08-10
Volume
40
Issue
3
Pages
325-342
ISSN
  • 0742-5554 (ISSN-L)
  • 0883-6612
  • 1532-4796
DOI
10.1007/s12160-010-9216-2
PMC
PMC4101802
OpenAlex
W2013987273
Cited by
419
References
110
Citations by year
2026: 11 · 2025: 26 · 2024: 24 · 2023: 16 · 2022: 29 · 2021: 45 · 2020: 39 · 2019: 23 · 2018: 20 · 2017: 35 · 2016: 32 · 2015: 40 · 2014: 27 · 2013: 18 · 2012: 26
FWCI
2.04
Type
journal article
Language
en
Open access
Locations
  • Annals of Behavioral Medicine (publishedVersion)
  • PubMed (publishedVersion)
  • Europe PMC (PubMed Central) (acceptedVersion)
  • PubMed Central (acceptedVersion)
Funders
  • National Institute on Aging (R01AG026010)
  • National Institute of Nursing Research (R01NR009573)
  • National Institute of Diabetes and Digestive and Kidney Diseases (R01DK060586)
Topics
  • Social Sciences › Psychology › Social Psychology › Attachment and Relationship Dynamics
  • Health Sciences › Nursing › Research and Theory › Nursing care and research
  • Health Sciences › Medicine › Oncology › Cancer survivorship and care
Keywords
chronic disease, marital relationships, depressive symptoms, marital functioning, pain, cancer, arthritis, cardiovascular disease, chronic pain, HIV, type 2 diabetes, partner support, psychosocial interventions, health behavior
MeSH terms
Chronic Disease, Female, Humans, Interpersonal Relations, Male, Marriage, Patient Education as Topic, Self Care, Health Behavior, Treatment Outcome

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