A Hope-based intervention to address disrupted goal pursuits and quality of life among young adult cancer survivors
Open accessAbstract
Over 70,000 US young adults are diagnosed with cancer annually, disrupting important life transitions and goal pursuits. Hope is a positive psychology construct associated with better quality of life (QOL) that focuses on goal-oriented thinking. We developed and tested Achieving Wellness After Kancer in Early life (AWAKE), a scalable 8-week app-based program consisting of educational videos, mood/activity tracking, and telephone-based coaching to promote hope and QOL in young adult cancer survivors (YACS, 18-40 years old). A two-arm RCT was used to examine the feasibility, acceptability, and potential efficacy of AWAKE (n = 38) versus attention control (AC; n = 18) among YACS within 2 years of completing treatment and recruited from two NCI-designated cancer centers. Outcomes including hope (Trait Hope Scale), QOL (36-Item Short Form Health Survey; Functional Assessment of Cancer Therapy-General), depressive symptoms (Patient Health Questionnaire-9), and substance use were assessed at baseline, 8 weeks, and 6 months. Participants were an average of 32.55 (SD = 5.45) years old; 75.0% were female, and 80.4% White. The most common cancers were breast cancer (28.6%), melanoma (16.1%), and leukemia/lymphoma (12.5%). High retention, engagement, and satisfaction rates were documented in both conditions; AWAKE versus AC participants rated video content as more relevant (p = 0.007) and reported greater likelihood of talking positively about the program (p = 0.005). Many efficacy change scores showed positive trends in AWAKE versus AC. Reorienting to one's goal pursuits after cancer diagnosis and treatment is critical and may be supported through hope-based interventions. Findings suggest that the AWAKE warrants subsequent research testing its efficacy, effectiveness, and scalability.
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- Findingown data
AWAKE participants were more likely than AC participants to have talked with friends or family about the program and comment positively about it (p=.005).
“Compared to AC participants, AWAKE participants were more likely to have talked with friends or family about the program and comment positively about it (p=.005).”
Quote in the paperNot a substantial claim - Findingown data
Large proportions of AWAKE and AC participants recommended keeping coaching in the program (94.3% and 88.2%, respectively).
“large proportions of AWAKE and AC participants recommended keeping the coaching in the program (94.3% and 88.2%, respectively).”
Quote in the paperSubstantial claim - Findingown data
At follow-up, greater increases in SF-36 physical functioning were related to higher rates of completion of any AWAKE component (r=.39, p=.020).
“At FU, two outcomes were related to higher engagement in the program: 1) greater increases in SF-36 physical functioning (related to higher rates of completion of any component: r=.39, p=.020);”
Quote in the paperNot a substantial claim - Findingown data
Over 80% of AWAKE participants recommended keeping behavior/mood tracking and homework in the program.
“Over 80% of AWAKE participants also recommended keeping the behavior/mood tracking and homework in the program.”
Quote in the paperNot a substantial claim - Findingown data
High proportions of participants in both groups (>88%) indicated they would recommend the program to friends who are cancer survivors.
“High proportions of participants in both groups (>88%) indicated that they would recommend the program to friends who are cancer survivors.”
Quote in the paperNot a substantial claim
- Findingown data
These feasibility and acceptability dimensions were indicated in both AWAKE and AC conditions.
“However, these dimensions of feasibility and acceptability were indicated in both the AWAKE and the AC conditions.”
Quote in the paperNot a substantial claim - Findingown data
Of the 38 AWAKE participants, 8 (21.1%) engaged in less than 75% of program weeks for any component.
“Of the 38 AWAKE participants, 8 (21.1%) engaged in <75% (<6 of 8) weeks of program in relation to any component.”
Quote in the paperNot a substantial claim - Findingown data
AWAKE participants rated video content as more relevant than AC participants (p=.007).
“AWAKE participants rated the content of the videos as more relevant, relative to AC participants (p=.007).”
Quote in the paperNot a substantial claim - Findingnone given
Engagement with the AWAKE intervention was associated with better outcomes among those in the AWAKE program.
“Engagement with the AWAKE intervention was also associated with better outcomes among those in the AWAKE program.”
Quote in the paperSubstantial claim - Findingown data
The proportion recommending keeping the videos trended toward being greater among AWAKE versus AC participants (p=.071).
“The proportion who recommended keeping the videos trended toward being greater among AWAKE versus AC participants (p=.071).”
Quote in the paperNot a substantial claim - Findingown data
The study successfully recruited over 50% of participants who were reached and met eligibility.
“we successfully recruited over 50% of participants who were reached and met eligibility for the current study.”
Quote in the paperNot a substantial claim - Interpretationown data
Despite a small sample size, the study indicated anticipated trends in primary and secondary efficacy outcomes, particularly in follow-up assessments of changes in hope and its components.
“Despite a small sample size, this study indicated anticipated trends in primary and secondary efficacy outcomes, particularly in relation to FU assessments of changes in hope and its components.”
Quote in the paperSubstantial claim - Premisecitation
A brief one-session hope-based intervention increased hope and pain tolerance among 172 young adults.
“a brief one-session hope-based intervention targeting hope and pain tolerance resulted in increased hope and pain tolerance among 172 young adults [27].”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites [27] Berg CJ, Snyder CR, Hamilton N (2008) The effectiveness of a hope intervention in coping with cold pressor pain. J Health Psychol 13(6):804–809 source
Not checked in the free run.
- Study design and conductreasoning
The sample was limited in generalizability and diversity (e.g., racial, ethnic) because participants were recruited from two NCI-designated cancer centers in the South.
“The sample was also limited in terms of generalizability and diversity (e.g., racial, ethnic), as participants were recruited from two NCI-designated cancer centers in the South; this has implications for future scalability.”
Quote in the paperNot a substantial claim - Interpretationreasoning
The AWAKE approach is highly scalable given its app-based nature and brief telephone coach interactions.
“this approach is highly scalable given its app-based nature and the brief interactions with coaches via telephone.”
Quote in the paperSubstantial claim - Study design and conductreasoning
The study was underpowered to examine associations between AWAKE engagement and outcomes to establish a dose-response relationship.
“we were underpowered to examine the associations between engagement in the AWAKE intervention in relation to outcomes in order to establish whether there was a dose-response relationship.”
Quote in the paperNot a substantial claim - Interpretationown data
The AWAKE intervention is acceptable, even when compared to a relatively relevant and useful AC condition.
“These results indicate that the AWAKE intervention is acceptable, even when comparing it to a relatively relevant and useful AC condition.”
Quote in the paperSubstantial claim - Study design and conductcitation
The Adult Trait Hope Scale is a psychometrically sound measure of hope.
“This scale is a psychometrically sound measure [35, 36]”
Quote in the paperSubstantial claim0 of 2 sources checked- cites [35] Babyak MA, Snyder CR, Yoshinobu L (1993) Psychometric properties of the hope scale: a confirmatory factor analysis. J Res Pers 27:154–169 source
Not checked in the free run.
- cites [36] Cheavens J, Gum A, Snyder CR (2000) The Trait Hope Scale. In: Maltby CAL, Hill A (eds) Handbook of psychological tests. Mellen Press, Lampeter, pp 248–258
Not checked in the free run.
- Interpretationcitation
This study highlights the potential utility of positive psychology constructs, particularly hope, in supporting YACS cope with cancer-related sequelae and re-establish goals across life domains after cancer, a relevant challenge facing many cancer survivors, particularly in young adulthood.
“Moreover, this study highlights the potential utility of positive psychology constructs, particularly hope, in supporting YACS cope with cancer-related sequelae and re-establish goals across life domains after the cancer experience, a particularly relevant challenge facing many cancer survivors, particularly in young adulthood [2].”
Quote in the paperSubstantial claim0 of 1 sources checked- cites [2] Hullmann SE, Robb SL, Rand KL (2015) Life goals in patients with cancer: a systematic review of the literature. Psycho-Oncology 25(4):387–399 source
Not checked in the free run.
- Classified as probably not a substantial claim. 14
- May combine two claims. 34
Probably not a substantial claim: may not pass S3 (load-bearing).
Findingown dataThe final sample size was 56 after excluding 7 withdrawals.
“Excluding withdrawals (n=7, most of whom withdrew due to time constraints), our final sample size was N=56.”
Quote in the paperNot a substantial claimProbably not a substantial claim: may not pass S3 (load-bearing). May combine two claims.
Findingown dataParticipants had a mean age of 32.55 years (SD=5.45); 75.0% were female, 80.4% White, 7.1% Hispanic, and 67.9% married or living with a partner.
“Participants were an average 32.55 (SD=5.45) years old; 75.0% were female, 80.4% White, 7.1% Hispanic, and 67.9% married or living with their partner (Table 2).”
Quote in the paperNot a substantial claimMay combine two claims.
Findingown dataAt follow-up, greater reductions in number of days of alcohol use were related to more videos watched (r=−.62, p<.001), more coaching calls completed (r=−.62, p<.001), and higher rates of completion of any AWAKE component (r=−.68, p<.001).
“2) greater reductions in number of days of alcohol use (related to more videos watched: r=−.62, p<.001; more coaching calls completed: r=−.62, p<.001; and higher rates of completion of any component: r=−.68, p<.001).”
Quote in the paperSubstantial claimMay combine two claims.
Findingown dataAt end-of-treatment, greater increases in SF-36 pain-related functioning were related to more videos watched (r=.63, p<.001), more coaching calls completed (r=.40, p=.022), and higher rates of completion of any AWAKE component (r=.59, p<.001).
“At EOT, three outcomes were related to higher engagement in the program: 1) greater increases in SF-36 pain-related functioning (related to more videos watched: r=.63, p<.001; more coaching calls completed: r=.40, p=.022; and higher rates of completion of any component: r=.59, p<.001);”
Quote in the paperNot a substantial claimMay combine two claims.
Findingown dataGreater improvements from baseline to follow-up were found in overall hope (p=.083), pathways thinking (p=.052), and SF-36 general health (p=.038) among AWAKE versus AC participants.
“Particularly noteworthy trends included greater improvements from baseline to FU in overall hope (p=.083) and pathways thinking (p=.052), as well as general health (per the SF-36, p=.038);”
Quote in the paperNot a substantial claimMay combine two claims.
Findingown dataAt end-of-treatment, greater reductions in number of days of alcohol use were related to more videos watched (r=−.49, p=.002), more coaching calls completed (r=−.40, p=.013), and higher rates of completion of any AWAKE component (r=−.52, p=.001).
“3) greater reductions in number of days of alcohol use (related to more videos watched: r=−.49, p=.002; more coaching calls completed: r=−.40, p=.013; and higher rates of completion of any component: r=−.52, p=.001).”
Quote in the paperNot a substantial claimMay combine two claims.
Findingown dataA vast majority of participants recommended keeping the videos and coaching and indicated they would recommend the program (>88%), and on average they were highly satisfied.
“a vast majority of participants recommended keeping the videos and coaching in the program and indicated that they would recommend the program (>88%); on average, they also indicated being highly satisfied with the program.”
Quote in the paperSubstantial claimMay combine two claims.
Findingown dataGreater improvements from baseline to end-of-treatment were found in FACT-G social/family well-being (p=.078) and PHQ-9 depressive symptoms (p=.061) among AWAKE versus AC participants.
“greater improvements from baseline to EOT were also found in social/family well-being (per the FACT-G, p=.078) and depressive symptoms (per the PHQ-9, p=.061).”
Quote in the paperNot a substantial claimMay combine two claims.
FindingreasoningThe study included a broad range of cancer types and participants within two years of treatment completion, underscoring diversity in cancer-related factors and sociodemographic diversity.
“However, we included a broad range of cancer types and those within two years of treatment completion, underscoring the diversity of the sample in terms of cancer-related factors, not to mention the sociodemographic diversity of the sample.”
Quote in the paperNot a substantial claimMay combine two claims.
Findingown dataThe study maintained high retention (exceeding 85%) and adherence (80% exceeding 75% retention).
“We were also able to maintain high retention (exceeding 85%) and adherence (80% exceeding 75% retention).”
Quote in the paperSubstantial claimMay combine two claims.
Findingown dataFew significant differences were found in change scores, but many change scores trended in the anticipated direction of greater improvements among AWAKE versus AC participants.
“While few significant differences were found, many change scores trended in the anticipated direction (i.e., greater improvements among AWAKE vs. AC participants).”
Quote in the paperNot a substantial claimProbably not a substantial claim: may not pass S3 (load-bearing). May combine two claims.
Findingown dataNo participants reported cigarette use, so that outcome was not reported.
“(No participants reported cigarette use, so this outcome was not reported in the results.)”
Quote in the paperNot a substantial claimMay combine two claims.
Findingown dataAt end-of-treatment, greater increases in FACT-G physical well-being were related to more videos watched (r=.34, p=.050) and higher rates of completion of any AWAKE component (r=.39, p=.024).
“2) greater increases in FACT-G physical well-being (related to more videos watched: r=.34, p=.050; and higher rates of completion of any component: r=.39, p=.024);”
Quote in the paperNot a substantial claimProbably not a substantial claim: may not pass S3 (load-bearing). May combine two claims.
Findingown dataDays of marijuana use increased in AWAKE participants but decreased in AC participants (p=.053).
“One trend was identified in the unexpected direction – days of marijuana use increased in AWAKE participants but decreased in AC participants (p=.053).”
Quote in the paperNot a substantial claimProbably not a substantial claim: may not pass S3 (load-bearing). May combine two claims.
Findingown dataThe most common cancer types were breast (28.6%), melanoma (16.1%), and leukemia/lymphoma (12.5%), and average time since diagnosis was 2.07 years (SD=0.77).
“The most common cancer types were breast (28.6%), melanoma (16.1%), and leukemia/lymphoma (12.5%), and average time since diagnosis was 2.07 (SD=0.77) years.”
Quote in the paperNot a substantial claimMay combine two claims.
InterpretationcitationIntegrating positive psychology, particularly hope, into YACS patient care might enhance mental health, coping, health behaviors, and overall QOL.
“Integrating positive psychology – and hope in particular – into YACS patient care might be strategic in the process of enhancing mental health [33], coping [24, 26, 27, 33], health behaviors [28–30], and overall QOL [31, 33].”
Quote in the paperSubstantial claim0 of 7 sources checked- cites [33] Cheavens J, Feldman DB, Gum A, Michael ST, Snyder CR (2006) Hope therapy in a community sample. Soc Indic Res 77:61–78 source
Not checked in the free run.
- cites [24] Snyder CR (2002) Hope theory: rainbows in the mind. Psychol Inq 13:249–275 source
Not checked in the free run.
- cites [26] Stanton AL, Danoff-Burg S, Cameron CL, Bishop M, Collins CA, Kirk SB, Sworowski LA (2000) Emotionally expressive coping predicts psychological and physical adjustment to breast cancer. J Consult Clin Psychol 68(5):875–882 source
Not checked in the free run.
- cites [27] Berg CJ, Snyder CR, Hamilton N (2008) The effectiveness of a hope intervention in coping with cold pressor pain. J Health Psychol 13(6):804–809 source
Not checked in the free run.
- cites [28] Berg CJ, Ritschel LA, Swan DW, An LC, Ahluwalia JS (2011) The role of hope in engaging in healthy behaviors among college students. Am J Health Behav 35(4):402–415
Not checked in the free run.
- cites [29] Coleman S, Berg CJ, Thompson NJ (2014) Social support, nutrition intake, and physical activity in cancer survivors. Am J Health Behav 38(3):414–419 source
Not checked in the free run.
- cites [30] Berg CJ, Thomas AN, Mertens AC, Schauer GL, Pinsker EA, Ahluwalia JS, Khuri FR (2012) Correlates of continued smoking versus cessation among survivors of smoking-related cancers. Psycho-Oncology 22(4):799–806 source
Not checked in the free run.
May combine two claims.
Study design and conductown dataOnly two baseline differences were found between AWAKE and AC: more AC participants were married or living with a partner (p=.031), and AWAKE participants had higher role limitations due to physical health scores (p=.042).
“Only two differences between the AWAKE and AC conditions were found; specifically, more AC than AWAKE participants were married or living with a partner (p=.031) and AWAKE participants had higher scores on role limitations due to physical health compared to AC participants (p=.042), indicating higher functioning.”
Quote in the paperNot a substantial claimMay combine two claims.
InterpretationcitationCurrent findings, along with prior studies, suggest that hope is a highly relevant and potentially impactful intervention target, particularly for YACS, and could be addressed through a scalable intervention such as AWAKE.
“Current findings, along with findings of these other studies, suggest that hope is a highly relevant and potentially impactful intervention target, particularly for YACS [2], and could be addressed through a scalable intervention such as AWAKE.”
Quote in the paperSubstantial claim0 of 1 sources checked- cites [2] Hullmann SE, Robb SL, Rand KL (2015) Life goals in patients with cancer: a systematic review of the literature. Psycho-Oncology 25(4):387–399 source
Not checked in the free run.
May combine two claims.
PremisecitationA hope-based intervention by Rustoen et al. increased hope immediately after therapy but hope decreased at three and twelve months post-treatment.
“Results indicated an increase in hope levels immediately after therapy, but reductions in hope thereafter (three and twelve months post-treatment).”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites [32] Rustoen T, Cooper BA, Miaskowski C (2011) A longitudinal study of the effects of a hope intervention on levels of hope and psychological distress in a community-based sample of oncology patients. Eur J Oncol Nurs 15(4):351–357 source
Not checked in the free run.
May combine two claims.
Study design and conductnone givenThe study was limited by a small sample size, which limited detection of differences between groups, particularly effects of AWAKE versus AC.
“Study limitations include small sample size, limiting the extent to which we could detect differences between groups, particularly effects of the AWAKE intervention versus AC.”
Quote in the paperNot a substantial claimProbably not a substantial claim: may not pass S3 (load-bearing).
Study design and conductown dataCronbach's alphas for FACT-G well-being subscales were .84, .84, .81, and .89.
“Cronbach’s alphas for each of the well-being subscales were as follows: physical: .84, social/family: .84, emotional: .81, and functional: .89.”
Quote in the paperNot a substantial claimProbably not a substantial claim: may not pass S3 (load-bearing).
Study design and conductown dataCronbach's alphas for SF-36 subscales ranged from .79 to .94.
“Cronbach’s alpha for each subscale were as follows: physical functioning: .89, role limitations due to physical health: .82, role limitations due to emotional problems: .89, energy/fatigue: .84, emotional well-being: .79, social functioning: .85, pain: .94, and general health: .83.”
Quote in the paperNot a substantial claimProbably not a substantial claim: may not pass S3 (load-bearing).
PremisecitationIn 2018, an estimated 70,000 new cancer cases were diagnosed among adolescents and young adults aged 15-39 in the US.
“In 2018, 70,000 new cancer cases were estimated to be diagnosed among adolescents and young adults between ages 15–39 [3].”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites [3] NCI Surveillance, E., and End Results Program (SEER) (2018) NCI Surveillance, Epidemiology, and End Results Program (SEER) 2018. https://seer.cancer.gov/. Accessed April 16, 2019
Not checked in the free run.
Classified as probably not a substantial claim. May combine two claims.
Study design and conductreasoningParticipants were randomized in a 2:1 ratio to AWAKE versus AC to allow examination of associations between AWAKE engagement and outcomes.
“We randomized participants in a 2:1 ratio for the AWAKE intervention versus AC condition in order to be able to examine associations between engagement in the AWAKE intervention in relation to outcomes.”
Quote in the paperSubstantial claimProbably not a substantial claim: may not pass S3 (load-bearing).
Study design and conductown dataParticipants were randomized to study arms using a pre-determined blocked random number sequence, stratified by sex and age.
“randomized to a study arm per a pre-determined blocked random number sequence, with stratification of sex (male vs. female) and age (18–30 vs. 31–39 years old).”
Quote in the paperNot a substantial claimProbably not a substantial claim: may not pass S3 (load-bearing). May combine two claims.
Study design and conductown dataThe PHQ-9 has a range of 0 to 27, with higher scores indicating more depressive symptoms, and its baseline Cronbach's alpha was .77.
“This measure has a range of 0 to 27, with higher scores indicating higher depressive symptoms. Cronbach’s alpha for this measure at baseline was .77.”
Quote in the paperNot a substantial claimProbably not a substantial claim: may not pass S3 (load-bearing).
InterpretationreasoningThe operationalization of hope by Snyder and used in this study transcends the ways hope may be differentially valued or perceived across cultures or religious groups.
“the operationalization of hope by Snyder [24] and used in this study transcends the ways in which hope may be differentially valued or perceived across cultures or religious groups.”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites [24] Snyder CR (2002) Hope theory: rainbows in the mind. Psychol Inq 13:249–275 source
Not checked in the free run.
Probably not a substantial claim: may not pass S3 (load-bearing).
Study design and conductnone givenThere was inherent difficulty ascertaining differences between those enrolled and retained versus those not enrolled or retained.
“In addition, there was inherent difficulty ascertaining differences between those enrolled and retained versus those not enrolled or retained.”
Quote in the paperNot a substantial claimMay combine two claims.
PremisecitationYoung adult cancer survivors report more life goal disturbances than older cancer patients, and these disturbances are linked to negative psychological outcomes.
“compared to older patients, young adult cancer survivors (YACS) report more life goal disturbances [2], which are related to negative psychological outcomes [2].”
Quote in the paperSubstantial claim0 of 1 sources checked- cites [2] Hullmann SE, Robb SL, Rand KL (2015) Life goals in patients with cancer: a systematic review of the literature. Psycho-Oncology 25(4):387–399 source
Not checked in the free run.
May combine two claims.
InterpretationcitationHope-based interventions can increase some psychological strengths, reduce some psychopathology symptoms, and enhance coping with physical symptoms.
“These results suggest that hope-based interventions can increase some psychological strengths, reduce some symptoms of psychopathology, and enhance coping with physical symptoms.”
Quote in the paperSubstantial claimMay combine two claims.
Study design and conductreasoningThe study used a strong AC condition to control for time spent in coaching and attending to intervention content, which may have impacted ability to detect differences.
“we used a strong AC condition, as we aimed to have sufficient relevance of the content to engage participants in order to control for time spent in coaching and attending to intervention content. This may have impacted our ability to detect differences/effects.”
Quote in the paperNot a substantial claimProbably not a substantial claim: may not pass S3 (load-bearing).
PremisecitationMore than 60% of adolescents and young adults experience adverse physical, psychosocial, or behavioral outcomes months or years after cancer treatment.
“Over 60% of adolescents and young adults will suffer adverse physical, psychosocial, and/or behavioral outcomes months or years after completion of cancer treatment [3–6].”
Quote in the paperNot a substantial claim0 of 4 sources checked- cites [3] NCI Surveillance, E., and End Results Program (SEER) (2018) NCI Surveillance, Epidemiology, and End Results Program (SEER) 2018. https://seer.cancer.gov/. Accessed April 16, 2019
Not checked in the free run.
- cites [4] Ketterl TG, Syrjala KL, Casillas J, Jacobs LA, Palmer SC, McCabe MS, Ganz PA, Overholser L, Partridge A, Rajotte EJ, Rosenberg AR, Risendal B, Rosenstein DL, Baker KS (2019) Lasting effects of cancer and its treatment on employment and finances in adolescent and young adult cancer survivors. Cancer 125(11):1908–1917 source
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- cites [5] Tai E, Buchanan N, Townsend J, Fairley T, Moore A, Richardson LC (2012) Health status of adolescent and young adult cancer survivors. Cancer 118(19):4884–4891 source
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- cites [6] Tai E, Buchanan N, Westervelt L, Elimam D, Lawvere S (2014) Treatment setting, clinical trial enrollment, and subsequent outcomes among adolescents with cancer: a literature review. Pediatrics 133:S91–S97 source
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May combine two claims.
PremisecitationHigher hope is associated with lower binge drinking and smoking, more exercise, and better nutrition in groups including young adults and cancer survivors.
“higher hope – in groups including young adults and cancer survivors – is related to lower rates of binge drinking and smoking, more frequent exercising, and better nutrition [28–30]”
Quote in the paperSubstantial claim0 of 3 sources checked- cites [28] Berg CJ, Ritschel LA, Swan DW, An LC, Ahluwalia JS (2011) The role of hope in engaging in healthy behaviors among college students. Am J Health Behav 35(4):402–415
Not checked in the free run.
- cites [29] Coleman S, Berg CJ, Thompson NJ (2014) Social support, nutrition intake, and physical activity in cancer survivors. Am J Health Behav 38(3):414–419 source
Not checked in the free run.
- cites [30] Berg CJ, Thomas AN, Mertens AC, Schauer GL, Pinsker EA, Ahluwalia JS, Khuri FR (2012) Correlates of continued smoking versus cessation among survivors of smoking-related cancers. Psycho-Oncology 22(4):799–806 source
Not checked in the free run.
May combine two claims.
Study design and conductown dataNo differences were found in retention at end-of-treatment or follow-up (exceeding 85%) or in number of coaching calls completed (averages exceeding 6 of 8 possible calls).
“No differences were found in relation to retention at EOT or FU (exceeding 85%) or number of coaching calls completed (averages exceeding 6 of 8 possible calls).”
Quote in the paperSubstantial claimMay combine two claims.
Study design and conductreasoningThe sample size allowed for 20% attrition from baseline to follow-up, yielding 15 in the AC group, and was sufficient to provide information on feasibility and acceptability and to estimate effect sizes for a subsequent efficacy trial.
“Allowing for 20% attrition from baseline to FU data collection (yielding 15 in the AC group), our sample size was able to yield valuable information regarding feasibility and acceptability. Additionally, this sample size allowed for estimating effect sizes to inform the design of the subsequent efficacy trial.”
Quote in the paperSubstantial claimMay combine two claims.
PremisecitationThe AWAKE intervention was based on an empirically supported protocol and augmented with additional evidence-based strategies, and it specifically targets the needs of YACS.
“The AWAKE intervention was based on an empirically-supported protocol [33], augmented with additional evidence-based strategies [27], and specifically targets the needs of YACS.”
Quote in the paperSubstantial claim0 of 2 sources checked- cites [33] Cheavens J, Feldman DB, Gum A, Michael ST, Snyder CR (2006) Hope therapy in a community sample. Soc Indic Res 77:61–78 source
Not checked in the free run.
- cites [27] Berg CJ, Snyder CR, Hamilton N (2008) The effectiveness of a hope intervention in coping with cold pressor pain. J Health Psychol 13(6):804–809 source
Not checked in the free run.
May combine two claims.
Study design and conductown dataCronbach's alpha for the Trait Hope Scale total, agency, and pathways subscales at baseline were .95, .91, and .89, respectively.
“Cronbach’s alpha for the total scale and for the agency and pathways subscales at baseline were .95, .91, and .89, respectively.”
Quote in the paperNot a substantial claimMay combine two claims.
PremisecitationHigher hope is associated with better adjustment in coping with breast cancer and better pain tolerance.
“higher hope is related to better adjustment in coping with cancer, specifically breast cancer [26], as well as better pain tolerance [27].”
Quote in the paperSubstantial claim0 of 2 sources checked- cites [26] Stanton AL, Danoff-Burg S, Cameron CL, Bishop M, Collins CA, Kirk SB, Sworowski LA (2000) Emotionally expressive coping predicts psychological and physical adjustment to breast cancer. J Consult Clin Psychol 68(5):875–882 source
Not checked in the free run.
- cites [27] Berg CJ, Snyder CR, Hamilton N (2008) The effectiveness of a hope intervention in coping with cold pressor pain. J Health Psychol 13(6):804–809 source
Not checked in the free run.
May combine two claims.
Study design and conductnone givenThe sample size allowed detection of a two-point change in hope scores, a 10-point change in SF-36 scores, a 15-point change in FACT-G scores, and a two-point change in PHQ-9 scores.
“This sample size allowed us to detect a two-point change hope scores, a 10-point change in SF-36 scores, a 15-point change in FACT-G scores, and a two-point change in PHQ-9 scores.”
Quote in the paperNot a substantial claimMay combine two claims.
PremisecitationHope is a subconstruct within quality of life that is particularly relevant for young adult cancer survivors.
“Hope is a subconstruct within the broader domain of QOL [23] that may be particularly relevant and important for YACS.”
Quote in the paperSubstantial claim0 of 1 sources checked- cites [23] Ferrell BR, Hassey Dow K, Grant M (1995) Measurement of the quality of life in cancer survivors. Qual Life Res 4(6):523–531 source
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May combine two claims.
PremisecitationA randomized wait-list control trial of an eight-session group treatment emphasizing goal-pursuit skills increased hope, life meaning, and self-esteem and reduced depression and anxiety symptoms in a community sample.
“Findings from a randomized, wait-list control trial using a community sample indicated that this intervention demonstrated efficacy in increasing hope, life meaning, and self-esteem as well as reductions in symptoms of depression and anxiety [33].”
Quote in the paperSubstantial claim0 of 1 sources checked- cites [33] Cheavens J, Feldman DB, Gum A, Michael ST, Snyder CR (2006) Hope therapy in a community sample. Soc Indic Res 77:61–78 source
Not checked in the free run.
May combine two claims.
Interpretationown dataThis study provides preliminary data suggesting that an app-based positive psychology intervention targeting hope is feasible and acceptable, with outcomes indicating trends such that AWAKE versus AC participants demonstrated larger improvements in psychological, functional, and substance use outcomes.
“This study provides preliminary data suggesting that an app-based positive psychology intervention, specifically targeting hope, is feasible and acceptable, with outcomes indicating trends such that participants in the AWAKE versus AC conditions demonstrated larger improvements in psychological, functional, and substance use outcomes.”
Quote in the paperSubstantial claim
The paper relies on this without support.
Few resources currently address the psychosocial needs of adolescent and young adult cancer survivors.
“However, few resources currently address these needs.”
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
Hope-based interventions have been shown effective in improving hope, quality of life, and mental health in young adult cancer survivors.
“as well as hope, quality of life, and mental health in YA cancer survivors [14].”
From A digital, coach-assisted intervention to address the psychosocial needs of young adult cancer survivors: Randomized controlled trial protocol and intervention adaptation process (2024) · cites this paper as [14]
The Results (Primary and Secondary Outcomes; page unavailable) report trends toward improvements in hope, aspects of quality of life, and depressive symptoms among young adult cancer survivors, but say that few differences between the intervention and control groups were significant. The Discussion (Conclusions; page unavailable) calls these preliminary findings and recommends a further trial to test efficacy. Thus, the paper does not establish that hope-based interventions have been shown effective across all three outcomes. (LLM, conf=0.88)
Experimental — accuracy not yet measuredThe pilot intervention demonstrated high satisfaction (3.14 on 0-4 scale; 88.9% would recommend to peers).
“high satisfaction (3.14 on 0-4 scale; 88.9% would recommend to peers)”
From A digital, coach-assisted intervention to address the psychosocial needs of young adult cancer survivors: Randomized controlled trial protocol and intervention adaptation process (2024) · cites this paper as [14]
The Results (Feasibility and Acceptability; page not available) report that more than 88% of participants in both groups would recommend the program to friends who are cancer survivors. The Discussion says participants were highly satisfied on average. Our copy does not give the claimed 3.14 score, 0–4 scale, or exact 88.9% figure. (LLM, conf=0.84)
Experimental — accuracy not yet measuredThe pilot results indicated areas for improvement, including overall satisfaction (M=3.14, SD=1.17), content relevance (M=3.14, SD=1.00), and engagement in homework activities (M=4.50, SD=2.31 of 8 completed).
“results indicated areas for improvement, for example, to increase overall satisfaction (M=3.14, SD=1.17), content relevance (M=3.14, SD=1.00 of 0=not at all to 4=very satisfied/relevant), and engagement in homework activities (M=4.50, SD=2.31 of 8 completed) [14].”
From A digital, coach-assisted intervention to address the psychosocial needs of young adult cancer survivors: Randomized controlled trial protocol and intervention adaptation process (2024) · cites this paper as [14]
The Methods (Measures/Data Collection; page unavailable) say the study assessed satisfaction and use of intervention components, and the Results (Feasibility and Acceptability; page unavailable) discuss video relevance and homework engagement. The passages in our copy do not give the cited means, standard deviations, or rating scale, so those numerical details cannot be verified. The Discussion describes participants as highly satisfied rather than identifying satisfaction as an area needing improvement. (LLM, conf=0.82)
Experimental — accuracy not yet measuredThe pilot intervention demonstrated high engagement in intervention components (average coaching sessions M=6.16, videos M=6.79, homework M=4.50).
“high engagement in intervention components (of 8 weeks, average number of completions: coaching sessions M=6.16, SD=2.83; videos M=6.79, SD=2.00; homework M=4.50, SD=2.31)”
From A digital, coach-assisted intervention to address the psychosocial needs of young adult cancer survivors: Randomized controlled trial protocol and intervention adaptation process (2024) · cites this paper as [14]
The Results (Feasibility and Acceptability; page unavailable) report an average of more than six of eight coaching calls, and the Discussion describes high adherence. Our copy does not give the claimed exact means or standard deviations for coaching, videos, or homework; it refers to Table 3 without reproducing those figures. (LLM, conf=0.86)
Experimental — accuracy not yet measuredThe 2017-2018 pilot trial developed and tested an 8-week app-based intervention with interactive phone-based coaching versus an attention control focused on finances among young adult cancer survivors recruited from 2 cancer centers (n=56; ages 18-39, within 2 years of completing primary treatment).
“In 2017-2018, our team developed and tested an 8-week app-based intervention with interactive phone-based coaching (vs. AC focused on finances) via an RCT among YA cancer survivors recruited from 2 cancer centers (n=56; ages 18-39, within 2 years of completing primary treatment; average age=32.55, SD=5.45; 75.0% female, 80.4% White, 28.6% breast cancer, 16.1% melanoma, 12.5% leukemia/lymphoma) [14”
From A digital, coach-assisted intervention to address the psychosocial needs of young adult cancer survivors: Randomized controlled trial protocol and intervention adaptation process (2024) · cites this paper as [14]
Split into 2 atoms — 1 confirmed, 1 partially supported, 0 disputed, 0 misattributed, 0 unverifiable. Expand the claim to see per-atom verdicts.
Experimental — accuracy not yet measured
In the pilot trial, session topics included hope and relevance to cancer survivorship; effective goal-setting and goal re-evaluation; interactions between thoughts, emotions, and goal pursuits; effectively managing thoughts and emotions; and addressing barriers to goals.
“In our pilot trial, session topics included: hope and relevance to cancer survivorship; effective goal-setting and goal re-evaluation; interactions between thoughts, emotions, and goal pursuits; effectively managing thoughts and emotions; and addressing barriers to goals (Table 1) [14].”
From A digital, coach-assisted intervention to address the psychosocial needs of young adult cancer survivors: Randomized controlled trial protocol and intervention adaptation process (2024) · cites this paper as [14]
The Methods (Study Design; page unavailable) say AWAKE had eight weekly modules with aligned homework and coaching on hope-related skills and goal pursuits. The Discussion (page unavailable) also describes setting goals and maintaining motivation despite barriers. Our copy does not specify the claimed session topics on interactions among thoughts, emotions, and goals or on managing thoughts and emotions, so it does not verify the full list. (LLM, conf=0.80)
Experimental — accuracy not yet measuredThe pilot intervention demonstrated feasibility (95% retention).
“The intervention demonstrated feasibility (95% retention)”
From A digital, coach-assisted intervention to address the psychosocial needs of young adult cancer survivors: Randomized controlled trial protocol and intervention adaptation process (2024) · cites this paper as [14]
The Results (Feasibility and Acceptability; page unavailable) report retention exceeding 85% at end of treatment and follow-up, and the Discussion describes the program as feasible. Neither passage substantiates the specific figure of 95% retention. (LLM, conf=0.85)
Experimental — accuracy not yet measuredWith 15% attrition to follow-up, n=127 allows detection of an effect size of ~0.32, sufficient to detect the modest effects documented in the previous pilot study.
“(With 15% attrition to FU, n=127 allows detection of an effect size of ~0.32, sufficient to detect the modest effects documented in the previous pilot study [14]).”
From A digital, coach-assisted intervention to address the psychosocial needs of young adult cancer survivors: Randomized controlled trial protocol and intervention adaptation process (2024) · cites this paper as [14]
The Results (Primary and Secondary Outcomes; page unavailable) report that few differences were significant, although several outcomes trended toward improvement in the intervention group. This supports using the pilot as evidence of promising effects, but the passages do not establish that those effects were of a particular modest magnitude. The 15% attrition, n=127, and detectable effect size of approximately 0.32 are the citing authors’ power calculation, not figures reported by this pilot. (LLM, conf=0.78)
Experimental — accuracy not yet measuredHope is a highly relevant construct for young adult survivors.
“One highly relevant construct is hope [14-16]”
Intervention participants rated educational video content as more relevant and reported greater likelihood of talking positively about the program compared to control.
“intervention (vs. control) participants rated educational video content as more relevant and reported greater likelihood of talking positively about the program [14].”
In our prior study, Cronbach's alpha for the Adult Hope Scale total, agency, and pathways were .95, .91, and .89, respectively.
“In our prior study, Cronbach’s alpha for the total scale, agency subscale, and pathways subscale were .95, .91, and .89, respectively [14].”
At 6-month follow-up, intervention participants reported greater increases in hope compared to control.
“at 6-month follow-up (FU), intervention participants reported greater increases in hope [14].”
This trial advances our prior pilot trial by using a more rigorous RCT with a larger sample, diversifying recruitment channels, updating the technological approach, and enhancing intervention content.
“This trial advances our prior pilot trial [14] by using a more rigorous RCT with a larger sample, diversifying the recruitment channels to include digital media to increase reach and accessibility among YA survivors, updating the technological approach for intervention delivery and its components to facilitate usability and scalability, and enhancing the intervention content to be more responsive”
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
Each contradiction between two passages listed here was confirmed by an independent check.
SF-36 subscale count does not match the paper's list
MinorThe methods say the SF-36 has nine subscales, but the subsequent list, described as covering each subscale, names only eight. The additional one-item measure is identified separately.
“The SF-36 is standardized to the general population and includes nine subscales (and an additional one-item measure).”
“Cronbach’s alpha for each subscale were as follows: physical functioning: .89, role limitations due to physical health: .82, role limitations due to emotional problems: .89, energy/fatigue: .84, emotional well-being: .79, social functioning: .85, pain: .94, and general health: .83.”
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The practice of hope in public health interventions: a qualitative single-case study
Broholm-Jørgensen, M. (2022) · Health Promotion International · doi:10.1093/heapro/daac144 · Cited by 4 · see citing works
Powis, M., Hack, S., Fazelzad, R., Hodgson, D. C., & Kukreti, V. (2023) · Journal of Cancer Survivorship · doi:10.1007/s11764-023-01500-3 · Cited by 3 · see citing works
Nugraheni, R., Murti, B., Irwanto, M. E., Sulaeman, E. S., & Pamungkasari, E. P. (2023) · Leprosy Review · doi:10.47276/lr.94.4.332 · Cited by 3 · see citing works
An Integrative Perspective on Understanding Human Functioning: Positive Clinical Psychology
Öztürk, Ö., & Maçkalı, Z. (2023) · Psikiyatride Guncel Yaklasimlar - Current Approaches in Psychiatry · doi:10.18863/pgy.1189803 · Cited by 3 · see citing works
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The Stress Process and Well-Being in Breast Cancer: The Mediating Role of Hope and Zest
Soria‐Reyes, L. M., Cerezo, M. V., Polak, A. T., & Blanca, M. J. (2025) · Integrative Cancer Therapies · doi:10.1177/15347354251396665 · Cited by 2 · see citing works
Sleep Treatment Education Program for Cancer Survivors: Protocol for an Efficacy Trial
Bice, B., Michaud, A. L., McCormick, K. G., Miklos, E. M., Descombes, I. D., Medeiros-Nancarrow, C., Zhou, E. S., & Recklitis, C. J. (2024) · JMIR Research Protocols · doi:10.2196/60762 · Cited by 2 · see citing works
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Self-citationMaintaining Hope in Transition: Critical to the Work of All Nurses
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Hope and Expanding Consciousness: Adolescents and Young Adults With Advanced Cancer
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Hope, depression, and psychiatric symptomology in adolescent cancer survivors
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- Authors
- Berg, C. J., Vanderpool, R. C., Getachew, B., Payne, J. B., Johnson, M. F., Sandridge, Y., Bierhoff, J., Le, L., Johnson, R., Weber, A., Patterson, A., Dorvil, S., & Mertens, A.
- Affiliations
- Emory University (US)
- University of Kentucky (US)
- Stony Brook University (US)
- Corresponding author
- Berg, Carla J.
- Venue
- Journal of Cancer Education
- Published
- 2019-07-11
- Volume
- 35
- Issue
- 6
- Pages
- 1158-1169
- ISSN
- 0885-8195 (ISSN-L)
- 1543-0154
- PMC
- PMC6954353
- OpenAlex
- W2957333726
- Cited by
- 59
- References
- 40
- Citations by year
- 2026: 2 · 2025: 7 · 2024: 12 · 2023: 15 · 2022: 13 · 2021: 6 · 2020: 3 · 2019: 1
- FWCI
- 2.40
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- Journal of Cancer Education (publishedVersion)
- PubMed (publishedVersion)
- PubMed Central (acceptedVersion)
- Funders
- Division of Cancer Prevention, National Cancer Institute (P30 CA138292)
- Division of Cancer Epidemiology and Genetics, National Cancer Institute (P30 CA177558)
- Topics
- Health Sciences › Medicine › Oncology › Cancer survivorship and care
- Social Sciences › Psychology › Applied Psychology › Optimism, Hope, and Well-being
- Health Sciences › Medicine › Pediatrics, Perinatology and Child Health › Childhood Cancer Survivors' Quality of Life
- Keywords
- hope, young adult cancer survivors, quality of life, goal pursuit, mobile health intervention, telephone coaching, educational videos, depressive symptoms, substance use, feasibility and acceptability, breast cancer, melanoma, leukemia and lymphoma
- MeSH terms
- Cancer Survivors, Adolescent, Adult, Behavior Therapy, Female, Goals, Humans, Male, Neoplasms, Quality of Life, Self Efficacy, Young Adult, Hope
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