Antifungal effect of lavender honey against Candida albicans, Candida krusei and Cryptococcus neoformans
Open accessAbstract
Monofloral lavender honey samples (n = 30), were analyzed to test antifungal effect against Candida albicans, Candida krusei, and Cryptococcus neoformans. The specific growth rates (μ) showed that all the yeast growths were reduced in the presence of honey. The honey concentration (% w/v) that inhibited 10% of the yeasts growth (X min) ranged from 31.0% (C. albicans), 16.8% (C. krusei) and 23.0% (C. neoformans). A synthetic honey solution was also tested to determine antifungal activity attributable to sugars. The presence of synthetic honey in the C. krusei culture medium at concentrations above 58.0% (w/v) was established as X min, while C. albicans and C. neoformans were more resistant, since X min values were not reached over the ranged tested (10-60%, w/v). What the data suggests is that the component in the lavender honey responsible for the observed antifungal in vitro properties is not sugar based. Honey might be tapped as a natural resource to look for new medicines for the treatment of mycotic infections. This could be very useful, onsidering the increasing resistance of antifungals. It should be noticed that this is the first study concerning the effect of lavender honey on the growth of pathogenic yeasts.
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The component(s) of honey responsible for the antifungal properties are not sugar based.
“It is therefore suggested that the component(s) of honey responsible for the antifungal properties are not sugar based.”
From Candida glabrata Biofilms: How Far Have We Come? (2017) · cites this paper as [243]
A synthetic honey solution had reduced antifungal activity compared to natural honey.
“This observation was also reported in the study of Estevinho et al. [243], where a synthetic honey solution was tested to determine the antifungal activity that was attributable to sugars, only to find that the activity was reduced compared to natural honey.”
From Candida glabrata Biofilms: How Far Have We Come? (2017) · cites this paper as [243]
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Candida glabrata Biofilms: How Far Have We Come?
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van Riel, S. J. J. M., Lardenoije, C. M. J. G., Oudhuis, G. J., & Cremers, N. A. J. (2021) · Journal of Fungi · doi:10.3390/jof7080664 · Cited by 22 · see citing works
- Authors
- Estevinho, M. L., Afonso, S. E., & Feás, X.
- Affiliations
- Universidade Politécnica de Bragança (PT)
- Universidade de Santiago de Compostela (ES)
- ORCID
- Feás, Xesús
- Venue
- Journal of Food Science and Technology
- Published
- 2011-02-11
- Volume
- 48
- Issue
- 5
- Pages
- 640-643
- ISSN
- 0022-1155 (ISSN-L)
- 0975-8402
- PMC
- PMC3551126
- OpenAlex
- W2040467146
- Cited by
- 69
- References
- 26
- Citations by year
- 2025: 2 · 2024: 4 · 2023: 11 · 2022: 7 · 2021: 5 · 2020: 3 · 2019: 7 · 2018: 4 · 2017: 6 · 2016: 5 · 2015: 5 · 2014: 2 · 2013: 5 · 2012: 2
- FWCI
- 3.60
- Type
- journal article
- Language
- en
- Open access
- green
- europepmc.org
- Licence
- www.springer.com/tdm (tdm)
- Locations
- Journal of Food Science and Technology (publishedVersion)
- Europe PMC (PubMed Central) (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Portuguese National Funding Agency for Science, Research and Technology (RCAAP Project by FCT) (submittedVersion, other-oa)
- Topics
- Life Sciences › Agricultural and Biological Sciences › Insect Science › Bee Products Chemical Analysis
- Life Sciences › Agricultural and Biological Sciences › Food Science › Essential Oils and Antimicrobial Activity
- Health Sciences › Medicine › Infectious Diseases › Antifungal resistance and susceptibility
- Keywords
- lavender honey, antifungal activity, Candida albicans, Candida krusei, Cryptococcus neoformans, pathogenic yeasts, honey sugars, mycotic infections, antifungal resistance, antifungal natural products
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