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Cited by 205Natural Antidiabetic Agents StudiesMedicinal Plant ResearchEthnobotanical and Medicinal Plants Studies

Role of medicinal plants in the management of diabetes mellitus: a review

Open access
Bindu Jacob, Narendhirakannan R.T.·2019·3 Biotech
DOI 10.1007/s13205-018-1528-0PMC PMC6291410
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Abstract

Medicinal plants have a vast potential in the treatment of various ailments due to the presence of therapeutically important phytochemicals. Diabetes is a serious metabolic disorder and several marketed medications are available to alleviate the symptoms of diabetes. However, these over the counter drugs are expensive and associated with several complications. Herbal medicines are gaining importance as they are cost-effective and also display improved therapeutic effects with lesser side effects. The present review includes the reports available on medicinal plants used for treating diabetes complications. The aim of the review is to categorize and summarize the available information on medicinal plants with anti-diabetic properties and suggesting outlooks for future research. A systematic search was performed on medicinal plants with anti-diabetic properties using several search engines such as Google Scholar, PubMed, Science Direct and other online journals and books. All the plants listed in this review are native to Asian countries and are routinely used by the traditional practitioners for the treatment of various ailments. Based on the literature data available, a total of 81 medicinal plants with anti-diabetic, anti-hyperglycemic, hypoglycemic, anti-lipidemic and insulin mimetic properties have been compiled in this review. This review provides useful information about the different medicinal plants for treating diabetes-associated complications. Further research can be carried out to study the active constituents and mechanism of these plants.

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  • Herbals/botanicals have demonstrated potent anti-diabetic effects via a variety of mechanisms, such as enhancing insulin sensitivity, stimulating insulin secretion, blocking carbohydrate absorption, and reducing oxidative stress.

    “Herbals/botanicals have demonstrated potent anti-diabetic effects via a variety of mechanisms, such as enhancing insulin sensitivity, stimulating insulin secretion, blocking the absorption of carbohydrates, and reducing OS; the inhibition of α-glucosidase enzyme and the generation of advanced glycation products, the transcription of GLUT-4 and PPAR, and the presence of antioxidants.”

    From A critical review on diabetes mellitus type 1 and type 2 management approaches: from lifestyle modification to current and novel targets and therapeutic agents. (2024) · cites this paper as [135]

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Cited by

Sorted by citations

Authors
Jacob, B., & Narendhirakannan, R. T.
Affiliations
Karunya University (IN)
Venue
3 Biotech
Publisher
Springer Science and Business Media LLC
Published
2018-12-12
Volume
9
Issue
1
Pages
4-4
ISSN
  • 2190-572X (ISSN-L)
  • 2190-5738
DOI
10.1007/s13205-018-1528-0
PMC
PMC6291410
OpenAlex
W2905442871
Cited by
205
References
1
Citations by year
2026: 9 · 2025: 47 · 2024: 44 · 2023: 30 · 2022: 34 · 2021: 20 · 2020: 14 · 2019: 7
FWCI
1.58
Type
journal article
Language
en
Open access
Licence
www.springer.com/tdm (tdm)
Locations
  • 3 Biotech (publishedVersion)
  • Europe PMC (PubMed Central) (publishedVersion)
  • PubMed Central (publishedVersion)
  • PubMed (publishedVersion)
Funders
Government of India via UGC’s Maulana Azad National Fellowship Scheme (F1-17.1/2015-16/MANF-2015-17-GUJ-69611)
Topics
  • Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Natural Antidiabetic Agents Studies
  • Life Sciences › Agricultural and Biological Sciences › Plant Science › Medicinal Plant Research
  • Life Sciences › Agricultural and Biological Sciences › Plant Science › Ethnobotanical and Medicinal Plants Studies
Keywords
medicinal plants, diabetes mellitus, antidiabetic activity, hypoglycemic activity, anti-lipidemic activity, insulin-like activity, diabetes complications, phytochemicals, traditional medicine

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