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Cited by 169Substance Abuse Treatment and OutcomesChild and Adolescent Psychosocial and Emotional DevelopmentAlcohol Consumption and Health Effects

Alcohol use and Depression During Adolescence and Young Adulthood: a Summary and Interpretation of Mixed Findings

Open access
Pedrelli, Paola, Shapero, Ben, Archibald, A., Dale, Chelsea·2016·Current Addiction Reports
DOI 10.1007/s40429-016-0084-0PMC PMC4859438
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Abstract

Alcohol use disorder (AUD) and alcohol misuse are common among adolescents and young adults and are associated with significant personal and societal problems. Similarly, major depressive disorder (MDD) and depressive symptoms are prevalent in this population and when they co-occur with alcohol misuse leads to even more severe consequences. Numerous studies have investigated the association between depressive symptoms, AUD, and various drinking behaviors presenting an unclear picture. In this review, we summarize studies among adolescents and young adults that have examined these relationships. From this review, it emerges that several factors affect results, including study design (cross-sectional vs longitudinal), participants’ age (adolescents vs young adults), severity of problems considered (AUD vs heavy drinking; MDD vs depressive symptoms), and gender. Adolescents with AUD are at higher risk for MDD in particular at a younger age. During adolescence, several drinking behaviors, including weekly alcohol use and heavy drinking, increase the risk for depressive symptoms and MDD, while during young adulthood primarily AUD, but not other drinking behaviors, is associated with increased risk for MDD. Gender may have an effect on the association between depression and drinking behaviors but its role is still unclear. Some evidence suggests that the association between AUD and MDD is bidirectional such that mood problems contribute to the onset of alcohol problems and vice versa. More longitudinal studies are needed to examine these associations in young adults and to clarify the effect of gender on these associations. To date, findings suggest the critical need to reduce any alcohol use at a young age and to treat both depressive symptoms and AUD to prevent the occurrence of comorbid disorders.

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  • Adolescent alcohol exposure is associated with increased rates of major depressive disorder, particularly in females.

    “AAE is associated with increased rates of major depressive disorder [45, 46], particularly in females [47].”

    From Consequences of adolescent drug use (2023) · cites this paper as [45]

    The Conclusion (page not provided) reports a higher risk of MDD among adolescents with alcohol use disorder and a small prospective increase in MDD risk associated with alcohol use. It also says findings on gender differences are mixed, so it does not establish that the association is particularly strong in females. (LLM, conf=0.88)

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Research works printed but not linked: 1

  1. [23]Arnett JJ Ramos KD Jensen LA 2001 Ideologies in emerging adulthood: Balancing the ethics of autonomy and community Journal of Adult Development 8 69 79

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Authors
Pedrelli, P., Shapero, B., Archibald, A., & Dale, C.
Affiliations
  • Harvard University (US)
  • Massachusetts General Hospital (US)
Corresponding author
Pedrelli, Paola
ORCID
Venue
Current Addiction Reports
Publisher
Springer Science and Business Media LLC
Published
2016-02-04
Volume
3
Issue
1
Pages
91-97
ISSN
2196-2952 (ISSN-L)
DOI
10.1007/s40429-016-0084-0
PMC
PMC4859438
OpenAlex
W2261646863
Semantic Scholar
d37d99cae61cfb189ccb8ab3f4e5bb1ea35afb4e
Cited by
169
References
71
Citations by year
2026: 8 · 2025: 22 · 2024: 25 · 2023: 13 · 2022: 35 · 2021: 23 · 2020: 12 · 2019: 12 · 2018: 8 · 2017: 8 · 2016: 3
FWCI
9.69
Type
journal article
Language
en
Open access
Licence
Locations
  • Current Addiction Reports (publishedVersion)
  • PubMed (publishedVersion)
  • PubMed Central (acceptedVersion)
Funders
National Institute on Alcohol Abuse and Alcoholism (K23AA020064)
Topics
  • Health Sciences › Medicine › Epidemiology › Substance Abuse Treatment and Outcomes
  • Social Sciences › Psychology › Clinical Psychology › Child and Adolescent Psychosocial and Emotional Development
  • Health Sciences › Medicine › Pathology and Forensic Medicine › Alcohol Consumption and Health Effects
Keywords
alcoholism, alcohol abuse, major depressive disorder, depressive symptoms, adolescents, young adults, heavy drinking, gender differences, bidirectional comorbidity

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