The relationships between use of alcohol, tobacco and coffee in adolescence and mood disorders in adulthood
Open accessAbstract
INTRODUCTION: Alcohol, tobacco and coffee are commonly used substances and use in adolescence has previously been linked to mood disorders. However, few large prospective studies have investigated adolescent use in relation to mental health outcomes in adulthood. The main aim of this study was to examine the prospective associations between alcohol use, cigarette smoking and coffee consumption at age 16 and subsequent mood disorders up to 33 years of age. METHODS: Data from The Northern Finland Birth Cohort 1986 Study were used and a total of 7660 participants (49.9% male) were included. Associations between alcohol use, cigarette smoking and coffee consumption at age 16 and later diagnoses of major depression and bipolar disorder were examined using multinomial logistic regression analyses. RESULTS: Mean number of cigarettes/day (OR, 1.23 [95% CI 1.01-1.50]) and mean volume of alcohol consumption (OR, 1.22 [95% CI 1.01-1.47]), but not frequency of excessive drinking, in adolescence were associated with increased risk for subsequent bipolar disorder after adjustment for sex, parental psychiatric disorders, family structure, illicit substance use, and emotional and behavioral problems at age 16. An association between cigarette smoking and major depression attenuated to statistically non-significant when adjusted for emotional and behavioral problems. No associations were observed between adolescent coffee consumption and subsequent mood disorders. CONCLUSIONS: This is the first study to report an association of adolescent cigarette smoking and subsequent bipolar disorder diagnosis providing grounds for further research and pointing to a place for preventive measures among adolescents.
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In a Finnish register study, the mean count of cigarettes per day at age 16 was associated with a higher risk of subsequent manifestation of bipolar disorder after adjustment for potential confounders (OR 1.23, 95% CI 1.01-1.50).
“A recent Finnish register study revealed that the mean count of cigarettes/day at age 16 were associated with a higher risk of subsequent manifestation of BD after adjustment for potential confounders (OR, 1.23 [95% CI 1.01–1.50]) (52).”
From The detrimental effects of smoking on the course and outcome in adults with bipolar disorder—A narrative review (2023) · cites this paper as [52]
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Cites
Manual for ASEBA School-Age Forms & Profiles
Achenbach, T. M. (2001) · Medical Entomology and Zoology · Cited by 4,676 · see citing works
The association of cigarette smoking with depression and anxiety: a systematic review
Fluharty, M., Taylor, A. E., Grabski, M., & Munafò, M. R. (2017) · Nicotine & Tobacco Research · doi:10.1093/ntr/ntw140 · Cited by 1,299 · see citing works
Family, twin, and adoption studies of bipolar disorder
Smoller, J. W., & Finn, C. T. (2003) · American Journal of Medical Genetics Part C Seminars in Medical Genetics · doi:10.1002/ajmg.c.20013 · Cited by 714 · see citing works
Tests of Causal Links Between Alcohol Abuse or Dependence and Major Depression
Fergusson, D. M., Boden, J. M., & Horwood, L. J. (2009) · Archives of General Psychiatry · doi:10.1001/archgenpsychiatry.2008.543 · Cited by 475 · see citing works
Chaiton, M. O., Cohen, J. E., O'Loughlin, J., & Rehm, J. (2009) · BMC Public Health · doi:10.1186/1471-2458-9-356 · Cited by 391 · see citing works
Cairns, K. E., Yap, M. B. H., Pilkington, P. D., & Jorm, A. F. (2014) · Journal of Affective Disorders · doi:10.1016/j.jad.2014.08.006 · Cited by 363 · see citing works
Comorbidity between major depression and alcohol use disorder from adolescence to adulthood
Brière, F. N., Rohde, P., Seeley, J. R., Klein, D., & Lewinsohn, P. M. (2014) · Comprehensive Psychiatry · doi:10.1016/j.comppsych.2013.10.007 · Cited by 328 · see citing works
Adult outcomes of binge drinking in adolescence: findings from a UK national birth cohort
Viner, R., & Taylor, B. (2007) · Journal of Epidemiology & Community Health · doi:10.1136/jech.2005.038117 · Cited by 312 · see citing works
Coffee, Caffeine, and Risk of Depression Among Women
Lucas, M. (2011) · Archives of Internal Medicine · doi:10.1001/archinternmed.2011.393 · Cited by 270 · see citing works
Energy drinks: health risks and toxicity
Gunja, N., & Brown, J. A. (2012) · The Medical Journal of Australia · doi:10.5694/mja11.10838 · Cited by 235 · see citing works
Grosso, G., Micek, A., Castellano, S., Pajak, A., & Galvano, F. (2015) · Molecular Nutrition & Food Research · doi:10.1002/mnfr.201500620 · Cited by 233 · see citing works
Luger, T. M., Suls, J., & Vander Weg, M. W. (2014) · Addictive Behaviors · doi:10.1016/j.addbeh.2014.05.011 · Cited by 231 · see citing works
Marmorstein, N. R. (2009) · Alcoholism: Clinical and Experimental Research · doi:10.1111/j.1530-0277.2008.00810.x · Cited by 219 · see citing works
Coffee components and cardiovascular risk: beneficial and detrimental effects
Godos, J., Pluchinotta, F. R., Marventano, S., Buscemi, S., Li Volti, G., Galvano, F., & Grosso, G. (2014) · International Journal of Food Sciences and Nutrition · doi:10.3109/09637486.2014.940287 · Cited by 210 · see citing works
Puddephatt, J., Irizar, P., Jones, A., Gage, S. H., & Goodwin, L. (2021) · Addiction · doi:10.1111/add.15735 · Cited by 208 · see citing works
Haukoos, J. S., & Newgard, C. D. (2007) · Academic Emergency Medicine · doi:10.1197/j.aem.2006.11.037 · Cited by 207 · see citing works
ESPAD Report 2019: Results From European School Survey Project on Alcohol and Other Drugs
Mokinaro, S., Vincente, J., Benedetti, E., et al. (2020) · Arrow - TU Dublin (Technological University Dublin) · doi:10.2810/877033 · Cited by 196 · see citing works
Caffeine consumption and self-assessed stress, anxiety, and depression in secondary school children
Richards, G., & Smith, A. (2015) · Journal of Psychopharmacology · doi:10.1177/0269881115612404 · Cited by 179 · see citing works
Haukoos, J. S., & Newgard, C. D. (2007) · Academic Emergency Medicine · doi:10.1111/j.1553-2712.2007.tb01855.x · Cited by 176 · see citing works
Pedrelli, P., Shapero, B., Archibald, A., & Dale, C. (2016) · Current Addiction Reports · doi:10.1007/s40429-016-0084-0 · Cited by 169 · see citing works
Hunt, G. E., Malhi, G. S., Cleary, M., Lai, H. M. X., & Sitharthan, T. (2016) · Journal of Affective Disorders · doi:10.1016/j.jad.2016.06.051 · Cited by 161 · see citing works
Li, J., Wang, H., Li, M., Shen, Q., Li, X., Zhang, Y., Peng, J., Rong, X., & Peng, Y. (2020) · Addiction · doi:10.1111/add.14935 · Cited by 161 · see citing works
Marangoni, C., Hernández, M., & Faedda, G. L. (2016) · Journal of Affective Disorders · doi:10.1016/j.jad.2015.12.055 · Cited by 157 · see citing works
Miettunen, J., Murray, G. K., Jones, P. B., Mäki, P., Ebeling, H., Taanila, A., Joukamaa, M., Savolainen, J., Törmänen, S., Järvelin, M.-R., et al. (2014) · Psychological Medicine · doi:10.1017/s0033291713002328 · Cited by 151 · see citing works
Self-citationTrends in Caffeine Intake Among US Children and Adolescents
Branum, A. M., Rossen, L. M., & Schoendorf, K. C. (2014) · Pediatrics · doi:10.1542/peds.2013-2877 · Cited by 151 · see citing works
Heffner, J. L., Strawn, J. R., DelBello, M. P., Strakowski, S. M., & Anthenelli, R. M. (2011) · Bipolar Disorders · doi:10.1111/j.1399-5618.2011.00943.x · Cited by 148 · see citing works
ICPC-3 International Classification of Primary Care
van Boven, K., & Napel, H. T. (2021) · CRC Press eBooks · doi:10.1201/9781003197157 · Cited by 144 · see citing works
The role of adenosine receptors in mood and anxiety disorders
van Calker, D., Biber, K. P. H., Domschke, K., & Serchov, T. (2019) · Journal of Neurochemistry · doi:10.1111/jnc.14841 · Cited by 142 · see citing works
Comparison of drinking patterns measured by daily reports and timeline follow back.
Searles, J. S., Helzer, J. E., & Walter, D. E. (2000) · Psychology of Addictive Behaviors · doi:10.1037//0893-164x.14.3.277 · Cited by 141 · see citing works
Batt, M. M., Duffy, K. A., Novick, A. M., Metcalf, C. A., & Epperson, C. N. (2020) · FOCUS The Journal of Lifelong Learning in Psychiatry · doi:10.1176/appi.focus.20190045 · Cited by 130 · see citing works
Ruusunen, A. A., Lehto, S. M., Tolmunen, T., Mursu, J., Kaplan, G. A., & Voutilainen, S. (2010) · Public Health Nutrition · doi:10.1017/s1368980010000509 · Cited by 119 · see citing works
Comparison of drinking patterns measured by daily reports and timeline follow back.
Searles, J. S., Helzer, J. E., & Walter, D. E. (2000) · Psychology of Addictive Behaviors · doi:10.1037/0893-164x.14.3.277 · Cited by 115 · see citing works
Excessive drinking and other problem behaviours among 14–16 year old schoolchildren
Best, D. W., Manning, V., Gossop, M., Gross, S., & Strang, J. (2006) · Addictive Behaviors · doi:10.1016/j.addbeh.2005.12.002 · Cited by 100 · see citing works
Yuan, S., Yao, H., & Larsson, S. C. (2020) · Scientific Reports · doi:10.1038/s41598-020-70458-4 · Cited by 94 · see citing works
Vermeulen, J. M., Wootton, R. E., Treur, J. L., Sallis, H. M., Jones, H. J., Zammit, S., van den Brink, W., Goodwin, G. M., de Haan, L., & Munafò, M. R. (2021) · The British Journal of Psychiatry · doi:10.1192/bjp.2019.202 · Cited by 78 · see citing works
Talati, A., Keyes, K. M., & Hasin, D. S. (2016) · Molecular Psychiatry · doi:10.1038/mp.2015.224 · Cited by 77 · see citing works
Torvik, F. A., Ystrøm, E., Gustavson, K., Rosenström, T. H., Bramness, J. G., Gillespie, N. A., Aggen, S. H., Kendler, K. S., & Reichborn‐Kjennerud, T. (2017) · Acta Psychiatrica Scandinavica · doi:10.1111/acps.12829 · Cited by 75 · see citing works
Self-citationHEAVY DRINKING OCCASIONS AND DEPRESSION
MANNINEN, L., Poikolainen, K., Vartiainen, E. A., & Laatikainen, T. K. (2006) · Alcohol and Alcoholism · doi:10.1093/alcalc/agh246 · Cited by 74 · see citing works
Edwards, A. C., Heron, J., Dick, D. M., Hickman, M., Lewis, G., Macleod, J., & Kendler, K. S. (2014) · Journal of Studies on Alcohol and Drugs · doi:10.15288/jsad.2014.75.758 · Cited by 65 · see citing works
Tobacco use in bipolar disorder
Thomson, D., Berk, M., Dodd, S., Rapado-Castro, M., Quirk, S. E., Ellegaard, P. K., Berk, L., & Dean, O. M. (2015) · Clinical Psychopharmacology and Neuroscience · doi:10.9758/cpn.2015.13.1.1 · Cited by 63 · see citing works
Kang, D., Kim, Y., & Je, Y. (2018) · European Journal of Clinical Nutrition · doi:10.1038/s41430-018-0121-2 · Cited by 63 · see citing works
Dimensions of Adolescent Alcohol Involvement as Predictors of Young-Adult Major Depression
Mason, W. A., Kosterman, R., Haggerty, K. P., Hawkins, J. D., Redmond, C. R., Spoth, R. L., & Shin, C. (2008) · Journal of Studies on Alcohol and Drugs · doi:10.15288/jsad.2008.69.275 · Cited by 61 · see citing works
Gogliettino, A. R., Potenza, M. N., & Yip, S. W. (2016) · Drug and Alcohol Dependence · doi:10.1016/j.drugalcdep.2016.02.015 · Cited by 56 · see citing works
Marmorstein, N. R. (2010) · Addictive Behaviors · doi:10.1016/j.addbeh.2010.01.004 · Cited by 53 · see citing works
Biological basis for the co-morbidity between smoking and mood disorders
Mineur, Y. S., & Picciotto, M. R. (2009) · Journal of Dual Diagnosis · doi:10.1080/15504260902869964 · Cited by 51 · see citing works
Coffee Consumption and the Risk of Depression in a Middle-Aged Cohort: The SUN Project
Navarro, A., Abasheva, D., Martínez‐González, M. Á., Ruiz-Estigarribia, L., Martín‐Calvo, N., Sánchez‐Villegas, A., & Toledo, E. (2018) · Nutrients · doi:10.3390/nu10091333 · Cited by 48 · see citing works
Hepatic Cannabinoid Signaling in the Regulation of Alcohol-Associated Liver Disease
Yang, K. (2021) · Alcohol research · doi:10.35946/arcr.v41.1.11 · Cited by 48 · see citing works
Substance use as a risk factor for bipolar disorder: A systematic review
Lalli, M., Brouillette, K., Kapczinski, F. P., & Cardoso, T. D. A. (2021) · Journal of Psychiatric Research · doi:10.1016/j.jpsychires.2021.10.012 · Cited by 48 · see citing works
Exploring Peers as a Mediator of the Association Between Depression and Smoking in Young Adolescents
Ritt‐Olson, A., Unger, J. B., Valente, T. W., Nezami, E., Chou, C., Trinidad, D. R., Milam, J. E., Earleywine, M., Tan, S., & Johnson, C. A. (2005) · Substance Use & Misuse · doi:10.1081/ja-200030505 · Cited by 39 · see citing works
Omagari, K., Sakaki, M., Tsujimoto, Y., Shiogama, Y., Iwanaga, A., Ishimoto, M., Yamaguchi, A., Masuzumi, M., Kawase, M., Ichimura‐Shimizu, M., et al. (2014) · Journal of Clinical Biochemistry and Nutrition · doi:10.3164/jcbn.14-30 · Cited by 31 · see citing works
Frigerio, S., Strawbridge, R., & Young, A. H. (2020) · Bipolar Disorders · doi:10.1111/bdi.12990 · Cited by 29 · see citing works
Sarala, M., Miettunen, J., Koskela, J., Mustonen, A., Rose, R. J., Hurtig, T. M., Veijola, J. M., & Niemelä, S. (2019) · Addiction · doi:10.1111/add.14889 · Cited by 18 · see citing works
Self-citationLess adolescent alcohol and cannabis use: More deviant user groups?
Pape, H., & Rossow, I. M. (2020) · Drug and Alcohol Review · doi:10.1111/dar.13146 · Cited by 18 · see citing works
Martínez-Ortega, J. M., Goldstein, B. I., Gutiérrez-Rojas, L., Sala, R., Wang, S., & Blanco, C. (2013) · Journal of Psychiatric Research · doi:10.1016/j.jpsychires.2013.03.012 · Cited by 17 · see citing works
Psychiatric research in the Northern Finland Birth Cohort 1986 – a systematic review
Miettunen, J., Haapea, M., Björnholm, L., Huhtaniska, S., Juola, T., Kinnunen, L., Lehtiniemi, H., Lieslehto, J., Rautio, N., & Nordström, T. (2019) · International Journal of Circumpolar Health · doi:10.1080/22423982.2019.1571382 · Cited by 8 · see citing works
Self-citationRognli, E. B., Bramness, J. G., & von Soest, T. (2021) · Psychological Medicine · doi:10.1017/s0033291720005401 · Cited by 6 · see citing works
Self-citation
Flagged first, then by citations
Cited by
Sorted by citations
Grunze, A., Mosolov, S., Grunze, H., & Born, C. (2023) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2022.1114432 · Cited by 11 · see citing works
- Authors
- Bolstad, I., Alakokkare, A., Bramness, J. G., Rognli, E. B., Levola, J., Mustonen, A., Miettunen, J., & Niemelä, S.
- Affiliations
- Innlandet Hospital Trust (NO)
- University of Turku (FI)
- Norwegian Institute of Public Health (NO)
- Oslo University Hospital (NO)
- University of Helsinki (FI)
- Tampere University (FI)
- Oulu University Hospital (FI)
- Corresponding author
- Bolstad, Ingeborg
- ORCID
- Venue
- Acta Psychiatrica Scandinavica
- Publisher
- Wiley
- Published
- 2022-10-05
- Volume
- 146
- Issue
- 6
- Pages
- 594-603
- ISSN
- 0001-690X (ISSN-L)
- 1600-0447
- PMC
- PMC9827971
- OpenAlex
- W4298088349
- Cited by
- 18
- References
- 56
- Citations by year
- 2026: 2 · 2025: 4 · 2024: 6 · 2023: 5 · 2022: 1
- FWCI
- 2.89
- Type
- journal article
- Language
- en
- Open access
- hybrid
- doi.org
- Licence
- Locations
- Acta Psychiatrica Scandinavica (publishedVersion, cc-by-nc-nd)
- PubMed Central (publishedVersion, cc-by-nc-nd)
- PubMed (publishedVersion)
- UTUPub (University of Turku) (submittedVersion)
- NORA - Norwegian Open Research Archives (submittedVersion, cc-by-nc-nd)
- NORA - Norwegian Open Research Archives (submittedVersion, other-oa)
- Työväentutkimus Vuosikirja (submittedVersion)
- Tampere University Institutional Repository (Tampere University) (submittedVersion, cc-by-nc-nd)
- Funders
- Academy of Finland
- Emil Aaltosen Säätiö
- Juho Vainion Säätiö
- Päivikki ja Sakari Sohlbergin Säätiö
- University of South Alabama
- Yrjö Jahnssonin Säätiö
- Topics
- Health Sciences › Medicine › Epidemiology › Substance Abuse Treatment and Outcomes
- Health Sciences › Medicine › Psychiatry and Mental health › Bipolar Disorder and Treatment
- Health Sciences › Medicine › Physiology › Smoking Behavior and Cessation
- Keywords
- adolescent alcohol use, adolescent cigarette smoking, mood disorders, bipolar disorder, major depressive disorder, adolescent substance use, emotional and behavioral problems, Northern Finland Birth Cohort 1986, prospective cohort
- MeSH terms
- Adolescent, Adult, Alcohol Drinking, Ethanol, Coffee, Female, Humans, Male, Prospective Studies, Risk Factors, Nicotiana, Tobacco Products, Mood Disorders, Substance-Related Disorders
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
