Comorbidity between major depression and alcohol use disorder from adolescence to adulthood
Open accessAbstract
Background Limited information exists regarding the long-term development of comorbidity between Major Depressive Disorder (MDD) and Alcohol Use Disorder (AUD; abuse/dependence). Using a representative prospective study, we examine multiple aspects pertaining to MDD+AUD comorbidity, with a focus on the relation between disorders across periods (adolescence, early adulthood, adulthood) and cumulative impairments by age 30.Method 816 participants were diagnostically interviewed at ages 16, 17, 24, and 30.Results Rates of comorbid MDD+AUD were low in adolescence (2%), but increased in early adulthood (11%) and adulthood (7%). Rates of cumulative comorbidity were elevated (21%). Most individuals with a history of MDD or AUD had the other disorder, except for women with MDD. Prospectively, adolescent AUD predicted early adult MDD, while early adult MDD predicted adult AUD. Compared to pure disorders, MDD+AUD was associated with higher risk of alcohol dependence, suicide attempt, lower global functioning, and life dissatisfaction.Conclusions Lifetime rates of comorbid MDD+AUD were considerably higher than in cross-sectional studies. Comorbidity was partly explained by bidirectional and developmentally-specific associations and predicted selected rather than generalized impairments. Clinically, our findings emphasize the need to always carefully assess comorbidity in patients with MDD or AUD, taking into account concurrency and developmental timing.
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
Developing MDD can have a pronounced detrimental impact on an individual's health behaviors, including sleep impairment, low motivation for physical activity, over/under-eating, and a propensity to self-medicate with tobacco, alcohol or substance use.
“On the other hand, developing MDD can have a pronounced detrimental impact on an individual's health behaviors, including sleep impairment, low motivation for physical activity, over/under-eating, and a propensity to self-medicate with tobacco, alcohol or substance use138,139.”
From Comorbidity between major depressive disorder and physical diseases: a comprehensive review of epidemiology, mechanisms and management (2023) · cites this paper as [139]
The Discussion (page not provided) reports that early-adult MDD predicted later AUD and proposes alcohol self-medication as one possible mechanism, while noting that the observed pattern did not frequently fit that mechanism. The paper does not support the claimed effects on sleep, physical activity, eating, or tobacco self-medication; the Methods (page not provided) explicitly exclude tobacco dependence from the substance-use diagnoses. (LLM, conf=0.88)
Experimental — accuracy not yet measured
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Cites
Diagnostic and Statistical Manual of Mental Disorders
Williams, J. B. W., & First, M. B. (2013) · Oxford University Press eBooks · doi:10.1093/acrefore/9780199975839.013.104 · Cited by 109,841 · see citing works
Diagnostic and Statistical Manual of Mental Disorders, 5th ed.
Carter, M. J. (2014) · Therapeutic Recreation Journal · Cited by 15,154 · see citing works
Principles and practice in reporting structural equation analyses.
McDonald, R. P., & Ho, M.-H. R. (2002) · Psychological Methods · doi:10.1037/1082-989x.7.1.64 · Cited by 4,734 · cited 1× · see citing works
“08) [30] was validated before examining individual paths.”
Hasin, D. S., Stinson, F. S., Ogburn, E., & Grant, B. F. (2007) · Archives of General Psychiatry · doi:10.1001/archpsyc.64.7.830 · Cited by 2,908 · see citing works
The self-medication hypothesis of addictive disorders: focus on heroin and cocaine dependence
(1985) · American Journal of Psychiatry · doi:10.1176/ajp.142.11.1259 · Cited by 2,538 · see citing works
The Structure of Common Mental Disorders
Krueger, R. F. (1999) · Archives of General Psychiatry · doi:10.1001/archpsyc.56.10.921 · Cited by 1,881 · see citing works
Angold, A., Costello, E. J., & Erkanli, A. (1999) · Journal of Child Psychology and Psychiatry · doi:10.1111/1469-7610.00424 · Cited by 1,872 · see citing works
Keller, M. B. (1987) · Archives of General Psychiatry · doi:10.1001/archpsyc.1987.01800180050009 · Cited by 1,643 · see citing works
Lewinsohn, P. M., Hops, H., Roberts, R. E., Seeley, J. R., & Andrews, J. A. (1993) · Journal of Abnormal Psychology · doi:10.1037/0021-843x.102.1.133 · Cited by 1,547 · see citing works
Self-citationDiagnostic and Statistical Manual of Mental Disorders
Davey, G. (2013) · Encyclopedia of Women in Today's World · doi:10.4135/9781412995962.n207 · Cited by 1,485 · see citing works
First, M. B., Spitzer, R. L., Gibbon, M., & Williams, J. B. W. (1997) · American Psychiatric Press eBooks · Cited by 983 · see citing works
Moffitt, T. E., Caspi, A., Taylor, A., Kokaua, J., Milne, B. J., Polanczyk, G., & Poulton, R. (2010) · Psychological Medicine · doi:10.1017/s0033291709991036 · Cited by 938 · see citing works
Retrospective Assessment of Prepubertal Major Depression with the Kiddie-SADS-E
Orvaschel, H., Puig-Antich, J., Chambers, W. J., Tabrizi, M. A., & JOHNSON, R. (1982) · Journal of the American Academy of Child Psychiatry · doi:10.1016/s0002-7138(09)60944-4 · Cited by 787 · see citing works
Merikangas, K., Mehta, R., Molnar, B. E., Walters, E., Swendsen, J., Aguilar-Gaziola, S., Bijl, R., Borges, G., Caraveo-anduaga, J., Dewit, D., et al. (1998) · Addictive Behaviours · doi:10.1016/s0306-4603(98)00076-8 · Cited by 776 · see citing works
Angold, A. C., Costello, E. J., & Erkanli, A. (1999) · PubMed · Cited by 723 · see citing works
Comorbidity between DSM-IV alcohol use disorders and major depression: results of a national survey
Grant, B. F., & Harford, T. C. (1995) · Drug and Alcohol Dependence · doi:10.1016/0376-8716(95)01160-4 · Cited by 637 · see citing works
Grant, B. F., Goldstein, R. B., Chou, S. P., Huang, B., Stinson, F. S., Dawson, D. A., Saha, T. D., Smith, S. M., Pulay, A. J., Pickering, R. P., et al. (2008) · Molecular Psychiatry · doi:10.1038/mp.2008.41 · Cited by 568 · see citing works
The Clinical Implications of Primary Diagnostic Groups Among Alcoholics
Schuckit, M. A. (1985) · Archives of General Psychiatry · doi:10.1001/archpsyc.1985.01790340021003 · Cited by 506 · see citing works
Tests of Causal Links Between Alcohol Abuse or Dependence and Major Depression
Fergusson, D. M., Boden, J. M., & Horwood, L. J. (2009) · Archives of General Psychiatry · doi:10.1001/archgenpsychiatry.2008.543 · Cited by 475 · see citing works
Comorbidity between substance use disorders and psychiatric conditions
Schuckit, M. A. (2006) · Addiction · doi:10.1111/j.1360-0443.2006.01592.x · Cited by 423 · see citing works
Rohde, P., Lewinsohn, P. M., Klein, D. N., Seeley, J. R., & Gau, J. M. (2012) · Clinical Psychological Science · doi:10.1177/2167702612457599 · Cited by 416 · see citing works
Self-citationA longitudinal study of the order of onset of alcohol dependence and major depression
Gilman, S. E., & Abraham, H. D. (2001) · Drug and Alcohol Dependence · doi:10.1016/s0376-8716(00)00216-7 · Cited by 293 · see citing works
Treatment of substance abusing patients with comorbid psychiatric disorders
Kelly, T. M., Daley, D. C., & Douaihy, A. B. (2011) · Addictive Behaviors · doi:10.1016/j.addbeh.2011.09.010 · Cited by 283 · see citing works
Disproportionate suicidality in patients with comorbid major depression and alcoholism
Cornelius, J. R., Salloum, I. M., Mezzich, J. E., Cornelius, M. D., Fábrega, H., Ehler, J. G., Ulrich, R. F., Thase, M. E., & Mann, J. J. (1995) · American Journal of Psychiatry · doi:10.1176/ajp.152.3.358 · Cited by 273 · see citing works
Natural Course of Alcohol Use Disorders From Adolescence to Young Adulthood
Rohde, P., Lewinsohn, P. M., Kahler, C. W., Seeley, J. R., & Brown, R. A. (2001) · Journal of the American Academy of Child & Adolescent Psychiatry · doi:10.1097/00004583-200101000-00020 · Cited by 231 · see citing works
Self-citationBoschloo, L., Vogelzangs, N., Smit, J. H., van den Brink, W., Veltman, D. J., Beekman, A. T. F., & Penninx, B. W. J. H. (2011) · Journal of Affective Disorders · doi:10.1016/j.jad.2010.12.014 · Cited by 210 · see citing works
Kranzler, H. R., Boca, F. K. D., & Rounsaville, B. J. (1996) · Journal of Studies on Alcohol · doi:10.15288/jsa.1996.57.619 · Cited by 184 · see citing works
Prognostic effect of the variable course of alcoholism on the 10-year course of depression
Mueller, T. I., Lavori, P. W., Keller, M. B., Swartz, A., Warshaw, M. G., Hasin, D. S., Coryell, W. H., Endicott, J., Rice, J. P., & Akiskal, H. S. (1994) · American Journal of Psychiatry · doi:10.1176/ajp.151.5.701 · Cited by 174 · see citing works
Kuo, P., Gardner, C. O., Kendler, K. S., & Prescott, C. A. (2006) · Psychological Medicine · doi:10.1017/s0033291706007860 · Cited by 163 · see citing works
The Validity of DSM‐IV Alcohol Dependence: What Do We Know and What Do We Need to Know?
Hasin, D. S., Schuckit, M. A., Martin, C. S., Grant, B. F., Bucholz, K. K., & Helzer, J. E. (2003) · Alcoholism Clinical and Experimental Research · doi:10.1097/01.alc.0000060878.61384.ed · Cited by 140 · see citing works
Alcohol use disorders and the course of depressive and anxiety disorders
Boschloo, L., Vogelzangs, N., van den Brink, W., Smit, J. H., Veltman, D. J., Beekman, A. T. F., & Penninx, B. W. J. H. (2012) · The British Journal of Psychiatry · doi:10.1192/bjp.bp.111.097550 · Cited by 128 · see citing works
Flensborg‐Madsen, T., Mortensen, E. L., Knop, J., Becker, U., Sher, L., & Grønbæk, M. (2008) · Comprehensive Psychiatry · doi:10.1016/j.comppsych.2008.09.003 · Cited by 104 · see citing works
Dawson, D. A., & Grant, B. F. (1998) · Journal of Studies on Alcohol · doi:10.15288/jsa.1998.59.97 · Cited by 102 · see citing works
Psychosocial functioning of adults who experienced substance use disorders as adolescents.
Rohde, P., Lewinsohn, P. M., Seeley, J. R., Klein, D. N., Andrews, J. A., & Small, J. W. (2007) · Psychology of Addictive Behaviors · doi:10.1037/0893-164x.21.2.155 · Cited by 97 · see citing works
Self-citationLongitudinal associations among depression, obesity and alcohol use disorders in young adulthood
McCarty, C. A., Kosterman, R., Mason, W. A., McCauley, E., Hawkins, J. D., Herrenkohl, T. I., & Lengua, L. J. (2009) · General Hospital Psychiatry · doi:10.1016/j.genhosppsych.2009.05.013 · Cited by 86 · see citing works
Grant, B. F., Hasin, D. S., & Dawson, D. A. (1996) · Journal of Affective Disorders · doi:10.1016/0165-0327(96)00002-x · Cited by 82 · see citing works
Bulloch, A. G. M., Lavorato, D. H., Williams, J. V. A., & Patten, S. B. (2012) · Depression and Anxiety · doi:10.1002/da.22001 · Cited by 69 · see citing works
Moffitt, T. E., Harrington, H., Caspi, A., Kim-Cohen, J., Goldberg, D., Gregory, A. M., & Poulton, R. (2007) · Archives of General Psychiatry · doi:10.1001/archpsyc.64.6.651 · Cited by 41 · see citing works
CO-MORBID DEPRESSION AND DRINKING OUTCOME IN THOSE WITH ALCOHOL DEPENDENCE
Davidson, K. M., & Blackburn, I. M. (1998) · Alcohol and Alcoholism · doi:10.1093/alcalc/33.5.482 · Cited by 38 · see citing works
Salloum, I. M., Mezzich, J. E., Cornelius, J. R., Day, N. L., Daley, D. C., & Kirisci, L. (1995) · Comprehensive Psychiatry · doi:10.1016/s0010-440x(95)90070-5 · Cited by 37 · see citing works
Flagged first, then by citations
Research works printed but not linked: 1
- [6]Angold A Costello EJ Erkanli A Comorbidity J Child Psychol Psychiatry 1999 40 1 57 87 10102726
Cited by
Sorted by citations
Aldao, A., Gee, D. G., De Los Reyes, A., & Seager, I. (2016) · Development and Psychopathology · doi:10.1017/s0954579416000638 · Cited by 636 · see citing works
Adult mental health outcomes of adolescent depression: A systematic review
Johnson, D., Dupuis, G., Piche, J., Clayborne, Z., & Colman, I. (2018) · Depression and Anxiety · doi:10.1002/da.22777 · Cited by 563 · see citing works
A hierarchical causal taxonomy of psychopathology across the life span.
Lahey, B. B., Krueger, R. F., Rathouz, P. J., Waldman, I. D., & Zald, D. H. (2017) · Psychological Bulletin · doi:10.1037/bul0000069 · Cited by 443 · see citing works
Lechner, W. V., Laurene, K. R., Patel, S. V., Anderson, M., Grega, C., & Kenne, D. R. (2020) · Addictive Behaviors · doi:10.1016/j.addbeh.2020.106527 · Cited by 358 · see citing works
Wang, J., Um, P. S., Dickerman, B. A., & Liu, J. (2018) · Nutrients · doi:10.3390/nu10050584 · Cited by 357 · see citing works
Berk, M., Köhler‐Forsberg, O., Turner, M., Penninx, B. W. J. H., Wrobel, A., Firth, J., Loughman, A., Reavley, N. J., McGrath, J. J., Momen, N. C., et al. (2023) · World Psychiatry · doi:10.1002/wps.21110 · Cited by 336 · see citing works
King, W. C., Chen, J.-Y., Courcoulas, A. P., Dakin, G. F., Engel, S. G., Flum, D. R., Hinojosa, M. W., Kalarchian, M. A., Mattar, S. G., Mitchell, J. E., et al. (2017) · Surgery for Obesity and Related Diseases · doi:10.1016/j.soard.2017.03.021 · Cited by 306 · see citing works
Neuroimmune signaling in alcohol use disorder
Erickson, E. K., Grantham, E. K., Warden, A. S., & Harris, R. A. (2018) · Pharmacology Biochemistry and Behavior · doi:10.1016/j.pbb.2018.12.007 · Cited by 224 · see citing works
Annual Research Review: Optimal outcomes of child and adolescent mental illness
Costello, E. J., & Maughan, B. (2014) · Journal of Child Psychology and Psychiatry · doi:10.1111/jcpp.12371 · Cited by 204 · see citing works
Esmaeelzadeh, S., Moraros, J., Thorpe, L. U., & Bird, Y. (2018) · Journal of Clinical Medicine · doi:10.3390/jcm7120543 · Cited by 187 · see citing works
Pedrelli, P., Shapero, B., Archibald, A., & Dale, C. (2016) · Current Addiction Reports · doi:10.1007/s40429-016-0084-0 · Cited by 169 · see citing works
Grabski, M., McAndrew, A., Lawn, W., Marsh, B., Raymen, L., Stevens, T., Hardy, L., Warren, F., Bloomfield, M., Borissova, A., et al. (2022) · American Journal of Psychiatry · doi:10.1176/appi.ajp.2021.21030277 · Cited by 175 · see citing works
Metacognitive beliefs in addictive behaviours: A systematic review
Hamonnière, T., & Varescon, I. (2018) · Addictive Behaviors · doi:10.1016/j.addbeh.2018.05.018 · Cited by 176 · see citing works
Nalugya, J., Rukundo, G. Z., Ovuga, E., Kiwuwa, S. M., Musisi, S., & Nakimuli‐Mpungu, E. (2016) · Child and Adolescent Psychiatry and Mental Health · doi:10.1186/s13034-016-0133-4 · Cited by 114 · see citing works
Sallie, S. N., Ritou, V., Bowden-Jones, H., & Voon, V. (2020) · BMJ Open · doi:10.1136/bmjopen-2020-044276 · Cited by 130 · see citing works
Kim, Y. H. (2017) · Child Abuse & Neglect · doi:10.1016/j.chiabu.2017.03.009 · Cited by 106 · see citing works
HCN2 channels in the ventral tegmental area regulate behavioral responses to chronic stress
Zhong, P., Vickstrom, C. R., Liu, X., Hu, Y., Yu, L., Yu, H.-G., & Liu, Q.-S. (2018) · eLife · doi:10.7554/elife.32420 · Cited by 99 · see citing works
“…disorder (MDD) are frequently comorbid in humans (Yoon et al., 2015), and that AUD can prospectively predict future MDD (Boschloo et al., 2012; Brière et al., 2014), a speculative mechanistic explanation is that chronic alcohol use leads to downregulation of HCN2 in VTA dopamine neurons,…”
BackgroundCarton, L., Pignon, B., Baguet, A., Benradia, I., Roelandt, J.-L., Vaïva, G., Thomas, P., Amad, A., de Timary, P., Naassïla, M., et al. (2018) · Drug and Alcohol Dependence · doi:10.1016/j.drugalcdep.2018.02.009 · Cited by 100 · see citing works
Neuroimmune Interface in the Comorbidity between Alcohol Use Disorder and Major Depression
Neupane, S. P. (2016) · Frontiers in Immunology · doi:10.3389/fimmu.2016.00655 · Cited by 97 · see citing works
Yin, H., Pantazatos, S. P., Galfalvy, H., Huang, Y., Rosoklija, G. B., Dwork, A. J., Burke, A., Arango, V., Oquendo, M. A., & Mann, J. J. (2016) · American Journal of Medical Genetics Part B: Neuropsychiatric Genetics · doi:10.1002/ajmg.b.32423 · Cited by 91 · see citing works
Epigenetic prediction of major depressive disorder
Barbu, M. C., Shen, X., Walker, R. M., Howard, D. M., Evans, K. L., Whalley, H. C., Porteous, D. J., Morris, S. W., Deary, I. J., Zeng, Y., et al. (2020) · Molecular Psychiatry · doi:10.1038/s41380-020-0808-3 · Cited by 88 · see citing works
Hasler, B. P., Martin, C. S., Wood, D. S., Rosario, B., & Clark, D. B. (2014) · Alcoholism: Clinical and Experimental Research · doi:10.1111/acer.12474 · Cited by 91 · see citing works
Stubbs, B., Vancampfort, D., Firth, J., Solmi, M., Siddiqi, N., Smith, L., Carvalho, A. F., & Koyanagi, A. (2018) · Journal of Psychiatric Research · doi:10.1016/j.jpsychires.2018.05.018 · Cited by 82 · see citing works
Vujanovic, A. A., Meyer, T. D., Heads, A. M. B., Stotts, A. L., Villarreal, Y. R., & Schmitz, J. M. (2016) · The American Journal of Drug and Alcohol Abuse · doi:10.1080/00952990.2016.1199697 · Cited by 83 · see citing works
Lee, K. M., Coehlo, M. A., Solton, N. R., & Szumlinski, K. K. (2017) · Frontiers in Psychology · doi:10.3389/fpsyg.2017.01128 · Cited by 72 · see citing works
Regulation of Craving and Negative Emotion in Alcohol Use Disorder
Suzuki, S., Mell, M. M., O’Malley, S. S., Krystal, J. H., Anticevic, A., & Hedy Kober, A. (2019) · Biological Psychiatry Cognitive Neuroscience and Neuroimaging · doi:10.1016/j.bpsc.2019.10.005 · Cited by 77 · see citing works
Risk of suicide ideation in comorbid substance use disorder and major depression
Onaemo, V. N., Fawehinmi, T. O., & D’Arcy, C. (2022) · PLoS ONE · doi:10.1371/journal.pone.0265287 · Cited by 69 · see citing works
A network approach to modeling comorbid internalizing and alcohol use disorders.
Anker, J. J., Forbes, M. K., Almquist, Z. W., Menk, J. S., THURAS, P. D., Unruh, A. S., & Kushner, M. G. (2017) · Journal of Abnormal Psychology · doi:10.1037/abn0000257 · Cited by 67 · see citing works
Preventing mental health conditions in adolescents living with HIV: an urgent need for evidence
Laurenzi, C. A., Skeen, S., Gordon, S. L., Akin-Olugbade, O., Abrahams, N., Bradshaw, M., Brand, A., Toit, S. D., Meléndez‐Torres, G. J., Tomlinson, M., et al. (2020) · Journal of the International AIDS Society · doi:10.1002/jia2.25556 · Cited by 64 · see citing works
Davis, E., Rotheram‐Borus, M. J., Weichle, T. W., Rezai, R., & Tomlinson, M. (2017) · AIDS and Behavior · doi:10.1007/s10461-017-1927-y · Cited by 61 · see citing works
Cano, M. Á., de Dios, M. A., Correa-Fernández, V., Childress, S. D., Abrams, J. L., & Roncancio, A. M. (2017) · Addictive Behaviors · doi:10.1016/j.addbeh.2017.03.015 · Cited by 60 · see citing works
Danzo, S., Connell, A. M., & Stormshak, E. A. (2017) · Journal of Adolescence · doi:10.1016/j.adolescence.2017.01.007 · Cited by 56 · see citing works
The causal web of foetal alcohol spectrum disorders: a review and causal diagram
McQuire, C., Daniel, R., Hurt, L. S., Kemp, A., & Paranjothy, S. (2019) · European Child & Adolescent Psychiatry · doi:10.1007/s00787-018-1264-3 · Cited by 58 · see citing works
Depression and Violence in Adolescence and Young Adults: Findings From Three Longitudinal Cohorts
Yu, R., Aaltonen, M., Branje, S., Ristikari, T., Meeus, W., Salmela‐Aro, K., Goodwin, G. M., & Fazel, S. (2017) · Journal of the American Academy of Child & Adolescent Psychiatry · doi:10.1016/j.jaac.2017.05.016 · Cited by 54 · see citing works
Shame mediates the relationship between depression and addictive behaviours
Bilevicius, E., Single, A. N., Bristow, L. A., Foot, M., Ellery, M., Keough, M. T., & Johnson, E. A. (2018) · Addictive Behaviors · doi:10.1016/j.addbeh.2018.02.023 · Cited by 55 · see citing works
Bolanis, D., Orri, M., Ryan, N. C., Renaud, J., Montreuil, T. C., Boivin, M., Vitaro, F., Tremblay, R. E., Turecki, G., Côté, S. M., et al. (2020) · Journal of Affective Disorders · doi:10.1016/j.jad.2020.05.136 · Cited by 53 · see citing works
Magee, K. E., & Connell, A. M. (2021) · Experimental and Clinical Psychopharmacology · doi:10.1037/pha0000436 · Cited by 53 · see citing works
Binge drinking and frequent or heavy drinking among adolescents: prevalence and associated factors
Conegundes, L. S. O., Valente, J. Y., Martins, C. B., Andreoni, S., & Sanchez, Z. M. (2018) · Jornal de Pediatria · doi:10.1016/j.jped.2018.08.005 · Cited by 50 · see citing works
Visontay, R., Mewton, L. R., Slade, T. N., Aris, I. M., & Sunderland, M. (2023) · American Journal of Psychiatry · doi:10.1176/appi.ajp.22010043 · Cited by 45 · see citing works
Nonhuman Primate Models of Depression: Effects of Early Experience and Stress
Worlein, J. M. (2014) · ILAR Journal · doi:10.1093/ilar/ilu030 · Cited by 42 · see citing works
Double screening for dual disorder, alcoholism and depression
Pavkovic, B., Zarić, M., Markovic, M., Klačar, M., Huljić, A., & Caričić, A. (2018) · Psychiatry Research · doi:10.1016/j.psychres.2018.10.013 · Cited by 43 · see citing works
Brenner, P., Brandt, L., Li, G., DiBernardo, A., Bodén, R., & Reutfors, J. (2019) · Addiction · doi:10.1111/add.14866 · Cited by 40 · see citing works
The natural history of substance use disorders
Sarvet, A. L., & Hasin, D. S. (2016) · Current Opinion in Psychiatry · doi:10.1097/yco.0000000000000257 · Cited by 39 · see citing works
Schouten, M. J. E., Christ, C., Dekker, J., Riper, H. M., Goudriaan, A. E., & Blankers, M. (2021) · Alcohol and Alcoholism · doi:10.1093/alcalc/agaa147 · Cited by 41 · see citing works
Rhew, I. C., Fleming, C. B., Stoep, A. V., Nicodimos, S., Zheng, C., & McCauley, E. (2017) · Addiction · doi:10.1111/add.13907 · Cited by 38 · see citing works
Continuity and change in neighborhood disadvantage and adolescent depression and anxiety
King, C., Huang, X., & Dewan, N. A. (2021) · Health & Place · doi:10.1016/j.healthplace.2021.102724 · Cited by 39 · see citing works
Paulus, D. J., Vujanovic, A. A., Schuhmann, B. B., Smith, L. J., & Tran, J. K. (2017) · Psychiatry Research · doi:10.1016/j.psychres.2017.02.011 · Cited by 39 · see citing works
Bilevicius, E., Single, A. N., Rapinda, K. K., Bristow, L. A., & Keough, M. T. (2018) · Addictive Behaviors · doi:10.1016/j.addbeh.2018.06.026 · Cited by 37 · see citing works
Bloch, S., Holleran, K. M., Kash, T. L., Vazey, E. M., Rinker, J. A., Lebonville, C. L., O’Hara, K., Lopez, M. F., Jones, S. R., Grant, K. A., et al. (2022) · Alcohol · doi:10.1016/j.alcohol.2022.02.001 · Cited by 35 · see citing works
Hogarth, L., Mathew, A. R., & Hitsman, B. L. (2017) · Drug and Alcohol Dependence · doi:10.1016/j.drugalcdep.2017.02.009 · Cited by 36 · see citing works
Crowley, N. A., Magee, S. N., Feng, M., Jefferson, S. J., Morris, C., Dao, N. C., Brockway, D. F., & Lüscher, B. (2019) · Neuropharmacology · doi:10.1016/j.neuropharm.2019.02.003 · Cited by 34 · see citing works
The association of religiosity with suicidal ideation and suicide attempts in the United Kingdom
Jacob, L., Haro, J. M., & Koyanagi, A. (2018) · Acta Psychiatrica Scandinavica · doi:10.1111/acps.12972 · Cited by 35 · see citing works
Laurent, J. S., & Sibold, J. (2015) · Journal of Pediatric Health Care · doi:10.1016/j.pedhc.2015.06.010 · Cited by 33 · see citing works
Depression and alcohol use disorders as precursors to death by suicide
Perez, J., Beale, E. E., Overholser, J. C., Athey, A. J., & Stockmeier, C. A. (2020) · Death Studies · doi:10.1080/07481187.2020.1745954 · Cited by 33 · see citing works
Inflammatory cytokines and alcohol use disorder: systematic review and meta-analysis
Moura, H. F., Hansen, F., Galland, F., Silvello, D., Rebelatto, F. P., Ornell, F. R., Massuda, R., Scherer, J. N., Schuch, F. B., Kessler, F. H. P., et al. (2022) · Brazilian Journal of Psychiatry · doi:10.47626/1516-4446-2021-1893 · Cited by 33 · see citing works
Davis, A., McMaster, P., Christie, D. C., Yang, A., Kruk, J. S., & Fisher, K. A. (2022) · International Journal of Mental Health and Addiction · doi:10.1007/s11469-022-00821-1 · Cited by 32 · see citing works
Walther, A., Rice, T., Kufert, Y., & Ehlert, U. (2017) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2016.00206 · Cited by 34 · see citing works
Cheah, S.-Y., Lawford, B. R., Young, R. M., Connor, J. P., Morris, C. P., & Voisey, J. (2014) · Alcohol and Alcoholism · doi:10.1093/alcalc/agu040 · Cited by 31 · see citing works
Parhiala, P., Ranta, K., Gergov, V., Kontunen, J., Law, R., Greca, A. M. L., Torppa, M., & MARTTUNEN, M. J. (2019) · School Mental Health · doi:10.1007/s12310-019-09346-w · Cited by 33 · see citing works
Bloch, S., Rinker, J. A., Marcus, M. M., & Mulholland, P. J. (2020) · Alcohol · doi:10.1016/j.alcohol.2020.07.011 · Cited by 29 · see citing works
Hernandez, R. V., Puro, A., Manos, J. C., Huitrón‐Reséndiz, S., Reyes, K. C., Liu, K., Vo, K., Roberts, A. J., & Gruol, D. L. (2015) · Neuropharmacology · doi:10.1016/j.neuropharm.2015.12.015 · Cited by 29 · see citing works
Carroll, A. J., Carnethon, M. R., Liu, K., Jacobs, D. R., Colangelo, L. A., Stewart, J. C., Carr, J. J., Widome, R., Auer, R., & Hitsman, B. L. (2016) · Health Psychology · doi:10.1037/hea0000425 · Cited by 29 · see citing works
Miguel, N., Marquez-Arrico, J. E., Jódar, M., Navarro, J. F., & Adán, A. (2023) · European Neuropsychopharmacology · doi:10.1016/j.euroneuro.2023.06.006 · Cited by 28 · see citing works
Binge drinking and subsequent depressive symptoms in young women in Australia
Powers, J. R., Duffy, L., Burns, L., & Loxton, D. J. (2016) · Drug and Alcohol Dependence · doi:10.1016/j.drugalcdep.2016.01.019 · Cited by 28 · see citing works
Seemiller, L. R., & Gould, T. J. (2020) · Neurobiology of Learning and Memory · doi:10.1016/j.nlm.2020.107234 · Cited by 23 · see citing works
Wang, C., Tong, Y., Tong, Y., Wang, X., Fang, L., Wen, X., Su, P., Wang, J., & Wang, G. (2024) · Asian Journal of Psychiatry · doi:10.1016/j.ajp.2024.104185 · Cited by 27 · see citing works
Tovmasyan, A., Monk, R. L., Sawicka, I., & Heim, D. (2022) · The American Journal of Drug and Alcohol Abuse · doi:10.1080/00952990.2022.2082300 · Cited by 26 · see citing works
Seemiller, L. R., Flores-Cuadra, J. A., Griffith, K. R., Smith, G. C., & Crowley, N. A. (2024) · Neurobiology of Stress · doi:10.1016/j.ynstr.2024.100605 · Cited by 26 · see citing works
Boutros, N., Der‐Avakian, A., Kesby, J. P., Lee, S., Markou, A., & Semenova, S. (2017) · Psychopharmacology · doi:10.1007/s00213-017-4789-0 · Cited by 26 · see citing works
Astrocytic GABAergic Regulation in Alcohol Use and Major Depressive Disorders
Ali, D. N., Ali, H. M., Lopez, M. R., Kang, S., & Choi, D. (2024) · Cells · doi:10.3390/cells13040318 · Cited by 26 · see citing works
Shin, S. H., Hassamal, S., & Groves, L. P. (2015) · American Journal on Addictions · doi:10.1111/ajad.12276 · Cited by 25 · see citing works
Psychiatric Comorbidity and Complications
Mason, M. J., Aplasca, A., Morales-Theodore, R., Zaharakis, N. M., & Linker, J. (2016) · Child and Adolescent Psychiatric Clinics of North America · doi:10.1016/j.chc.2016.02.007 · Cited by 25 · see citing works
The Internet Addiction Test in a Young Adult U.S. Population
Rosenthal, S. R., Cha, Y., & Clark, M. A. (2018) · Cyberpsychology Behavior and Social Networking · doi:10.1089/cyber.2018.0143 · Cited by 25 · see citing works
Gunn, R. L., Stevens, A. K., Micalizzi, L., Jackson, K. M., Borsari, B. E., & Metrik, J. (2020) · Experimental and Clinical Psychopharmacology · doi:10.1037/pha0000357 · Cited by 25 · see citing works
Schick, M. R., Weiss, N. H., Contractor, A. A., Dixon–Gordon, K. L., & Spillane, N. S. (2019) · The American Journal of Drug and Alcohol Abuse · doi:10.1080/00952990.2019.1572759 · Cited by 24 · see citing works
Principales daños sanitarios y sociales relacionados con el consumo de alcohol
Sarasa‐Renedo, A., Sordo, L., Molist, G., Hoyos, J., Guitart, A. M., & Barrio, G. (2014) · Revista Española de Salud Pública · doi:10.4321/s1135-57272014000400004 · Cited by 23 · see citing works
Zhu, K., Yang, T.-H. O., Dorie, V., Zheng, T., & Anastassiou, D. (2019) · Translational Psychiatry · doi:10.1038/s41398-018-0358-5 · Cited by 24 · see citing works
Bidirectional relationship between heroin addiction and depression: Behavioural and neural studies
Moustafa, A. A., Tindle, R., Cashel, S., Parkes, D., Mohamed, E., & Hamza, E. A. (2020) · Current Psychology · doi:10.1007/s12144-020-01032-4 · Cited by 24 · see citing works
Shim, E., Ha, H., Park, J. E., Kim, B., Chang, S. M., Hong, J. P., Cho, M. J., & Hahm, B. (2020) · Journal of Affective Disorders · doi:10.1016/j.jad.2020.03.162 · Cited by 23 · see citing works
Stumbling Into Adulthood: Learning From Depression While Growing Up
Grob, R., Schlesinger, M. J., Wise, M. E., & Pandhi, N. (2020) · Qualitative Health Research · doi:10.1177/1049732320914579 · Cited by 23 · see citing works
Ramirez, E. B. D., Arnold, M. E., McConnell, K. T., Solomon, M. G., Amico, K. N., & Schank, J. R. (2023) · Physiology & Behavior · doi:10.1016/j.physbeh.2023.114159 · Cited by 23 · see citing works
Yoon, G., Petrakis, I. L., & Rosenheck, R. A. (2015) · American Journal on Addictions · doi:10.1111/ajad.12219 · Cited by 23 · see citing works
Anterior Cingulate Cortex Implants for Alcohol Addiction: A Feasibility Study
Leong, S. L., Glue, P., Manning, P. J., Vanneste, S., Lim, L. J., Mohan, A., & Ridder, D. D. (2020) · Neurotherapeutics · doi:10.1007/s13311-020-00851-4 · Cited by 23 · see citing works
Lee, Y.-T., Huang, Y., Tsai, F., Liu, H., Sun, F., Tsai, Y.-J., & Liu, S. (2020) · Journal of the Formosan Medical Association · doi:10.1016/j.jfma.2020.05.003 · Cited by 22 · see citing works
Coach Support of High School Student-Athletes Struggling With Anxiety or Depression
Kroshus, E., Chrisman, S. P. D., Coppel, D. B., & Herring, S. A. (2018) · Journal of Clinical Sport Psychology · doi:10.1123/jcsp.2018-0004 · Cited by 22 · see citing works
Bohman, H., Låftman, S. B., Alaie, I., Ssegonja, R., & Jonsson, U. (2024) · European Child & Adolescent Psychiatry · doi:10.1007/s00787-024-02596-3 · Cited by 20 · see citing works
Subtypes of alcohol use disorder in the general population: A latent class analysis
Müller, M., Ajdacic‐Gross, V., Vetrella, A. B., Preisig, M., Castelao, E., Lasserre, A. M., Rodgers, S., Wulf Rössler, A., Vetter, S., Seifritz, E., et al. (2019) · Psychiatry Research · doi:10.1016/j.psychres.2019.112712 · Cited by 20 · see citing works
Substance use disorders among youth with chronic physical illness
Luther, A., Reaume, S. V., Qadeer, R. A., Thompson, K., & Ferro, M. A. (2020) · Addictive Behaviors · doi:10.1016/j.addbeh.2020.106517 · Cited by 21 · see citing works
Association between Alcohol Drinking Status and Depressive Symptoms in Korean Adults
Yang, J.-H., Choi, C. K., Kim, H., Heo, Y., & Shin, M. (2021) · Chonnam Medical Journal · doi:10.4068/cmj.2021.57.1.68 · Cited by 20 · see citing works
Gohari, M. R., Varatharajan, T., MacKillop, J. M., & Leatherdale, S. T. (2022) · Journal of Adolescent Health · doi:10.1016/j.jadohealth.2022.07.007 · Cited by 20 · see citing works
Howe, L. K., Fisher-Fox, L., Atkinson, E. A., & Finn, P. (2020) · Alcohol · doi:10.1016/j.alcohol.2020.11.002 · Cited by 20 · see citing works
Akter, S., Uddin, K. R., Sasaki, H., Lyu, Y., & Shibata, S. (2020) · Scientific Reports · doi:10.1038/s41598-020-67689-w · Cited by 19 · see citing works
Hernández-Serrano, O., Ghiţă, A., Fernández-Ruiz, J., Monràs, M., Gual, A., Gacto, M., Porras-García, B., Ferrer‐García, M., & Gutiérrez‐Maldonado, J. (2021) · Journal of Clinical Medicine · doi:10.3390/jcm10112241 · Cited by 19 · see citing works
Boden, J. M., & Foulds, J. (2016) · Journal of Affective Disorders · doi:10.1016/j.jad.2016.09.004 · Cited by 19 · see citing works
Gohari, M. R., Cook, R. J., Dubin, J. A., & Leatherdale, S. T. (2019) · Addictive Behaviors · doi:10.1016/j.addbeh.2019.106120 · Cited by 19 · see citing works
Bolstad, I., Alakokkare, A., Bramness, J. G., Rognli, E. B., Levola, J., Mustonen, A., Miettunen, J., & Niemelä, S. (2022) · Acta Psychiatrica Scandinavica · doi:10.1111/acps.13506 · Cited by 18 · see citing works
The protective effects of self-compassion on alcohol-related problems among first nation adolescents
Spillane, N. S., Schick, M. R., Goldstein, S. C., Nalven, T., & Kahler, C. W. (2021) · Addiction Research & Theory · doi:10.1080/16066359.2021.1902994 · Cited by 18 · see citing works
Depression and alcohol use in American Indian adolescents: The influence of family factors
Schick, M. R., Nalven, T., Thomas, E. D., Weiss, N. H., & Spillane, N. S. (2022) · Alcoholism Clinical and Experimental Research · doi:10.1111/acer.14748 · Cited by 18 · see citing works
Li, X., Xiao, D., Li, C., Wu, T., Li, L., Li, T., Pan, X., Liu, Q., Chi, M., Li, R., et al. (2024) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2024.116835 · Cited by 18 · see citing works
Paulus, D. J., Gallagher, M. W., Neighbors, C., & Zvolensky, M. J. (2021) · Behaviour Research and Therapy · doi:10.1016/j.brat.2021.103847 · Cited by 17 · see citing works
- Authors
- Brière, F. N., Rohde, P., Seeley, J. R., Klein, D., & Lewinsohn, P. M.
- Affiliations
- Université de Montréal (CA)
- Oregon Research Institute (US)
- Stony Brook University (US)
- Corresponding author
- Brière, Frédéric N.
- Venue
- Comprehensive Psychiatry
- Publisher
- Elsevier BV
- Published
- 2014-04
- Volume
- 55
- Issue
- 3
- Pages
- 526-533
- ISSN
- 0010-440X (ISSN-L)
- PMC
- PMC4131538
- OpenAlex
- W2072528158
- Cited by
- 328
- References
- 40
- Citations by year
- 2026: 11 · 2025: 34 · 2024: 37 · 2023: 29 · 2022: 39 · 2021: 28 · 2020: 41 · 2019: 32 · 2018: 29 · 2017: 19 · 2016: 13 · 2015: 8 · 2014: 6 · 2013: 1
- FWCI
- 6.81
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Comprehensive Psychiatry (publishedVersion)
- PubMed (publishedVersion)
- PubMed Central (acceptedVersion)
- Papyrus : Institutional Repository (Université de Montréal) (submittedVersion)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion)
- Funders
- National Institute on Alcohol Abuse and Alcoholism (R01AA020968, AA020968)
- National Institute of Mental Health (50522, R01MH052858, R01MH040501, MH40501, R01MH050522, MH 52858)
- National Institute on Drug Abuse (R01DA012951, DA12951)
- Topics
- Health Sciences › Medicine › Epidemiology › Substance Abuse Treatment and Outcomes
- Social Sciences › Psychology › Social Psychology › Mental Health Treatment and Access
- Social Sciences › Psychology › Clinical Psychology › Child and Adolescent Psychosocial and Emotional Development
- Keywords
- major depressive disorder, alcoholism, comorbidities, bidirectional relationship, developmental timing, adolescence, early adulthood, suicide attempts, global functioning, life dissatisfaction, women
- MeSH terms
- Adolescent, Adult, Alcoholism, Cross-Sectional Studies, Major Depressive Disorder, Depressive Disorder, Major, Female, Humans, Interviews as Topic, Longitudinal Studies, Male, Prospective Studies, Comorbidity, Prevalence, Young Adult
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
