Thyrotoxic periodic paralysis
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At a dose of 40 mg four times a day, propranolol prevented paralysis in carbohydrate-induced TPP in about two thirds of cases by inhibiting the activity of Na/K-ATPase.
“At a dose of 40 mg four times a day, propranolol prevented paralysis in carbohydrate-induced TPP in about two thirds of cases by inhibiting the activity of Na/K-ATPase [46].”
From Thyrotoxic Periodic Paralysis: Clinical Challenges (2014) · cites this paper as [46]
Propranolol, but not the selective beta1-blocker metoprolol, also effectively prevented recurrence of paralytic attacks or inhibited paralysis induced by a carbohydrate load.
“Propranolol, but not the selective beta1-blocker metoprolol, also effectively prevented recurrence of paralytic attacks or inhibited paralysis induced by a carbohydrate load.”
From Thyrotoxic Periodic Paralysis: Clinical Challenges (2014) · cites this paper as [46]
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- Authors
- Yeung, R. T. T., & Tse, T. F.
- Corresponding author
- Yeung, R.T.T.
- Venue
- The American Journal of Medicine
- Publisher
- Elsevier BV
- Published
- 1974-10
- Volume
- 57
- Issue
- 4
- Pages
- 584-590
- ISSN
- 0002-9343 (ISSN-L)
- OpenAlex
- W2051207689
- Cited by
- 115
- References
- 13
- Citations by year
- 2025: 1 · 2024: 3 · 2023: 1 · 2022: 3 · 2021: 3 · 2020: 1 · 2019: 1 · 2018: 4 · 2017: 1 · 2016: 1 · 2015: 4 · 2014: 2 · 2013: 2 · 2012: 3
- FWCI
- 2.22
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- The American Journal of Medicine (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Thyroid Disorders and Treatments
- Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Potassium and Related Disorders
- Health Sciences › Medicine › Surgery › Thyroid and Parathyroid Surgery
- Keywords
- thyrotoxic periodic paralysis, hyperthyroidism, high-carbohydrate diet, propranolol, acetazolamide, plasma insulin, insulin resistance, hypokalemia, lower limb weakness
- MeSH terms
- Acetazolamide, Blood Glucose, Dietary Carbohydrates, Glucose, Glucose Tolerance Test, Humans, Hyperthyroidism, Injections, Intravenous, Insulin, Male, Paralysis, Periodicity, Potassium, Propranolol, Sodium
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