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Cited by 1,123

The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.

Retinal Ganglion Cell Atrophy Correlated With Automated Perimetry in Human Eyes With Glaucoma

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Quigley, Harry A., Dunkelberger, Gregory R., Green, W. Richard·1989·American Journal of Ophthalmology
DOI 10.1016/0002-9394(89)90488-1
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Abstract

We measured the number and size of retinal ganglion cells from six human eyes with glaucoma. In each, the histologic findings were correlated with visual field results. Five age-matched normal eyes were studied for comparison. In general, there were fewer remaining large ganglion cells in retinal areas with atrophy. In the perifoveal area, however, no consistent pattern of cell loss by size was found. Our estimates suggest that visual field sensitivity in automated testing begins to decline soon after the initial loss of ganglion cells. Throughout the central 30 degrees of the retina, 20% of the normal number of cells were gone in locations with a 5-dB sensitivity loss, and 40% cell loss corresponded to a 10-dB decrease. There were some remaining ganglion cells in areas that had 0-dB sensitivity in the field test.

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Citations

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Show all 1 references

Research works printed but not linked: 30

  1. Quigley, 1981, Optic nerve damage in human glaucoma. II. The site of injury and susceptibility to damage, Arch. Ophthalmol., 99, 635, 10.1001/archopht.1981.03930010635009 · DOI · Paper page
  2. Quigley, 1980, Clinical evaluation of nerve fiber layer atrophy as an indicator of glaucomatous optic nerve damage, Arch. Ophthalmol., 98, 1564, 10.1001/archopht.1980.01020040416003 · DOI · Paper page
  3. Sommer, 1984, Evaluation of nerve fiber layer assessment, Arch. Ophthalmol., 102, 1766, 10.1001/archopht.1984.01040031430017 · DOI
  4. Quigley, 1982, Optic nerve damage in human glaucoma. III. Quantitative correlation of nerve fiber loss and visual field defect in glaucoma, ischemic neuropathy, disc edema, and toxic neuropathy, Arch. Ophthalmol., 100, 135, 10.1001/archopht.1982.01030030137016 · DOI · Paper page
  5. Quigley, 1983, Morphologic changes in the lamina cribrosa correlated with neural loss in open-angle glaucoma, Am. J. Ophthalmol., 95, 673, 10.1016/0002-9394(83)90389-6 · DOI · Paper page
  6. Leventhal, 1981, Retinal ganglion cell classes in old-world monkey. Morphology and central connections, Science, 213, 1139, 10.1126/science.7268423 · DOI
  7. Perry, 1981, The morphological correlates of X- and Y-like retinal ganglion cells in the retina of monkeys, Exp. Brain Res., 43, 426, 10.1007/BF00237768 · DOI
  8. DeMonasterio, 1978, Properties of concentrically organized X and Y ganglion cells of the retina of macaques, J. Neurophysiol., 41, 1394, 10.1152/jn.1978.41.6.1394 · DOI
  9. Lennie, 1980, Parallel visual pathways. A review, Vision Res., 20, 561, 10.1016/0042-6989(80)90115-7 · DOI · Paper page
  10. Rodieck, 1979, Visual pathways, Ann. Rev. Neurosci., 2, 193, 10.1146/annurev.ne.02.030179.001205 · DOI · Paper page
  11. Perry, V. H.: The ganglion cell layer of the mammalian retina. In Osborne, N., and Chader, G. (eds.): Progress in Retinal Research. Oxford, U.K., Pergamon Press, vol. 1, chap. 2, pp. 53–80. · DOI
  12. Quigley, 1987, Chronic glaucoma selectively damages large optic nerve fibers, Invest. Ophthalmol. Vis. Sci., 28, 913
  13. Quigley, 1988, Chronic human glaucoma causes selectively greater loss of large optic nerve fibers, Ophthalmology, 95, 357, 10.1016/S0161-6420(88)33176-3 · DOI · Paper page
  14. Perry, 1984, Retinal ganglion cells that project to the dorsal lateral geniculate nucleus in the macaque monkey, Neuroscience, 12, 1101, 10.1016/0306-4522(84)90006-X · DOI · Paper page
  15. Potts, 1972, Morphology of the primate optic nerve. II. Total fiber size distribution and fiber density distribution, Invest. Ophthalmol., 11, 989
  16. Asai, 1987, Retinal ganglion cell damage in human glaucoma. I. Studies on the somal diameter, Folia Ophthalmol. Jpn., 38, 701
  17. Atkin, 1979, Abnormalities of central contrast sensitivity in glaucoma, Am. J. Ophthalmol., 88, 205, 10.1016/0002-9394(79)90467-7 · DOI
  18. Tyler, 1981, Specific deficits of flicker sensitivity in glaucoma and ocular hypertension, Invest. Ophthalmol. Vis. Sci., 20, 204
  19. Trick, 1985, Retinal potentials in patients with primary open-angle glaucoma. Physiological evidence for temporal frequency tuning deficits, Invest. Ophthalmol. Vis. Sci., 26, 1750
  20. Johnson, M. L., Drum, B., Quigley, H. A., Sanchez, R., and Dunkelberger, G. R.: Pattern-evoked potentials and optic nerve fiber loss in monocular laser-induced glaucoma. Invest. Ophthalmol. Vis. Sci. In press.
  21. Marx, 1986, Flash and pattern electroretinograms in normal and laser-induced glaucomatous primate eyes, Invest. Ophthalmol. Vis. Sci., 27, 378
  22. Motolko, 1982, Visual field defects in low-tension glaucoma. Comparison of defects in low-tension glaucoma and chronic open angle glaucoma, Arch. Ophthalmol., 100, 1074, 10.1001/archopht.1982.01030040052005 · DOI
  23. Greve, E. L., and Geijssen, C.: Comparison of glaucomatous visual field defects in patients with high and with low intraocular pressures. In Greve, E. L., and Heijl, A. (eds.): Fifth International Visual Field Symposium. The Hague, Dr. W. Junk Publishers, 1983, pp. 101–105. · DOI
  24. Lewis, 1983, Optic disk and visual field correlations in primary open-angle and low-tension glaucoma, Am. J. Ophthalmol., 96, 148, 10.1016/S0002-9394(14)77781-5 · DOI
  25. Caprioli, 1984, Comparison of visual field defects in the low-tension glaucomas with those in the high-tension glaucomas, Am. J. Ophthalmol., 97, 730, 10.1016/0002-9394(84)90505-1 · DOI
  26. King, 1986, Comparison of visual field defects in normal-tension glaucoma and high-tension glaucoma, Am. J. Ophthalmol., 101, 204, 10.1016/0002-9394(86)90596-9 · DOI
  27. Bebie, 1976, Static perimetry. Accuracy and fluctuation, Acta Ophthalmol., 54, 339, 10.1111/j.1755-3768.1976.tb01263.x · DOI
  28. Brenton, 1987, Fluctuations on the Humphrey and Octopus perimeters, Invest. Ophthalmol. Vis. Sci., 28, 767
  29. Katz, 1987, A longitudinal study of the age-adjusted variability of automated visual fields, Arch. Ophthalmol., 105, 1083, 10.1001/archopht.1987.01060080085033 · DOI
  30. Heijl, 1987, Normal variability of static perimetric threshold values across the central visual field, Arch. Ophthalmol., 105, 1544, 10.1001/archopht.1987.01060110090039 · DOI

Cited by

Metadata

Authors
Quigley, H. A., Dunkelberger, G. R., & Green, W. R.
Venue
American Journal of Ophthalmology
Publisher
Elsevier BV
Published
1989-05
Volume
107
Issue
5
Pages
453-464
ISSN
0002-9394 (ISSN-L)
DOI
10.1016/0002-9394(89)90488-1
OpenAlex
W1970548437
Cited by
1,123
References
1
FWCI
17.66
Type
journal article
Language
en
Open access
hybrid
Licence

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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.