Evidences for vagus nerve in maintenance of immune balance and transmission of immune information from gut to brain in STM-infected rats

Vagus nerve stimulation attenuates the systemic inflammatory response to endotoxin

Borovikova, L. V., Ivanova, S., Zhang, M., Yang, H., Botchkina, G. I., Watkins, L. R., Wang, H., Abumrad, N., Eaton, J. W., & Tracey, K. J. (2000) · Nature · doi:10.1038/35013070 · Cited by 4,211 · see citing works

Mapping Patterns of c- fos Expression in the Central Nervous System After Seizure

Morgan, J. I., Cohén, D., Hempstead, J. L., & Curran, T. (1987) · Science · doi:10.1126/science.3037702 · Cited by 1,778 · see citing works

Functional and chemical anatomy of the afferent vagal system

Berthoud, H.-R., & Neuhuber, W. L. (2000) · Autonomic Neuroscience · doi:10.1016/s1566-0702(00)00215-0 · Cited by 1,280 · see citing works

Cytokine-to-brain communication: A review & analysis of alternative mechanisms

Watkins, L. R., Maier, S. F., & Goehler, L. E. (1995) · Life Sciences · doi:10.1016/0024-3205(95)02047-m · Cited by 597 · see citing works

Vagal immune-to-brain communication: a visceral chemosensory pathway

Goehler, L. E., Gaykema, R. P. A., Hansen, M. K., Anderson, K., Maier, S. F., & Watkins, L. R. (2000) · Autonomic Neuroscience · doi:10.1016/s1566-0702(00)00219-8 · Cited by 525 · see citing works

Characterization of cytokine-induced hyperalgesia

Watkins, L. R., Wiertelak, E. P., Goehler, L. E., Smith, K. P., Martin, D., & Maier, S. F. (1994) · Brain Research · doi:10.1016/0006-8993(94)91566-0 · Cited by 502 · see citing works

The Role of the Vagus Nerve in Cytokine‐to‐Brain Communication

Maier, S. F., Goehler, L. E., Fleshner, M., & Watkins, L. R. (1998) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.1998.tb09569.x · Cited by 439 · see citing works

Neural and humoral pathways of communication from the immune system to the brain: parallel or convergent?

Dantzer, R., Konsman, J.-P., Bluthé, R.-M., & Kelley, K. W. (2000) · Autonomic Neuroscience · doi:10.1016/s1566-0702(00)00220-4 · Cited by 400 · see citing works

Early-life exposure to endotoxin alters hypothalamic-pituitary-adrenal function and predisposition to inflammation

Shanks, N., Windle, R. J., Perks, P. A., Harbuz, M. S., Jessop, D. S., Ingram, C. D., & Lightman, S. L. (2000) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.090571897 · Cited by 374 · see citing works

Activation of Vagal Afferents after Intravenous Injection of Interleukin-1β: Role of Endogenous Prostaglandins

Ek, M., Kurosawa, M., Lundeberg, T., & Ericsson, A. B. (1998) · Journal of Neuroscience · doi:10.1523/jneurosci.18-22-09471.1998 · Cited by 370 · see citing works

Interleukin-1β in Immune Cells of the Abdominal Vagus Nerve: a Link between the Immune and Nervous Systems?

Goehler, L. E., Gaykema, R. P. A., Nguyen, K. T., Lee, J. E., Tilders, F. J. H., Maier, S. F., & Watkins, L. R. (1999) · Journal of Neuroscience · doi:10.1523/jneurosci.19-07-02799.1999 · Cited by 357 · see citing works

Vagal Paraganglia Bind Biotinylated Interleukin-1 Receptor Antagonist: A Possible Mechanism for Immune-to-Brain Communication

Goehler, L. E., Relton, J. K., Dripps, D. J., Kiechle, R., Tartaglia, N. R., Maier, S. F., & Watkins, L. R. (1997) · Brain Research Bulletin · doi:10.1016/s0361-9230(97)00020-8 · Cited by 326 · see citing works

Subdiaphragmatic vagotomy blocks induction of IL-1 beta mRNA in mice brain in response to peripheral LPS

Layé, S., Bluthé, R.-M., Kent, S., Combe, C., Medina, C. F., Parnet, P., Kelley, K., & Dantzer, R. (1995) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.1995.268.5.r1327 · Cited by 303 · see citing works

Evidence for an Intramedullary Prostaglandin-Dependent Mechanism in the Activation of Stress-Related Neuroendocrine Circuitry by Intravenous Interleukin-1

Ericsson, A. B., Arias, C., & Sawchenko, P. E. (1997) · Journal of Neuroscience · doi:10.1523/jneurosci.17-18-07166.1997 · Cited by 281 · see citing works

The afferent discharges from sensors for interleukin 1β in the hepatoportal system in the anesthetized rat

Niijima, A. (1996) · Journal of the Autonomic Nervous System · doi:10.1016/s0165-1838(96)00098-7 · Cited by 261 · see citing works

Implications of immune-to-brain communication for sickness and pain

Watkins, L. R., & Maier, S. F. (1999) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.96.14.7710 · Cited by 250 · see citing works

Characterization of CD4+ T Cell Responses During Natural Infection with Salmonella typhimurium

McSorley, S. J., Cookson, B. T., & Jenkins, M. K. (2000) · The Journal of Immunology · doi:10.4049/jimmunol.164.2.986 · Cited by 239 · see citing works

Neural immunoregulation: emerging roles for nerves in immune homeostasis and disease

Downing, J. R., & Miyan, J. A. (2000) · Immunology Today · doi:10.1016/s0167-5699(00)01635-2 · Cited by 235 · see citing works

Mechanisms of tumor necrosis factor-α (TNF-α) hyperalgesia

Watkins, L. R., Goehler, L. E., Relton, J. K., Brewer, M. T., & Maier, S. F. (1995) · Brain Research · doi:10.1016/0006-8993(95)00715-3 · Cited by 226 · see citing works

Subdiaphragmatic vagotomy suppresses endotoxin-induced activation of hypothalamic corticotropin-releasing hormone neurons and ACTH secretion.

Gaykema, R. P. A., Dijkstra, I., & Tilders, F. J. H. (1995) · Endocrinology · doi:10.1210/endo.136.10.7664696 · Cited by 212 · see citing works

Interleukin-1 mediates the behavioral hyperalgesia produced by lithium chloride and endotoxin

Maier, S. F., Wiertelak, E. P., Martin, D., & Watkins, L. R. (1993) · Brain Research · doi:10.1016/0006-8993(93)91446-y · Cited by 210 · see citing works

Intracerebroventricular administration of corticotropin-releasing factor inducesc-fos mRNA expression in brain regions related to stress responses: comparison with pattern ofc-fos mRNA induction after stress

Imaki, T., Shibasaki, T., Hotta, M., & Demura, H. (1993) · Brain Research · doi:10.1016/0006-8993(93)90199-w · Cited by 197 · see citing works

The vagus nerve in the thermoregulatory response to systemic inflammation

Romanovsky, A. A., Simons, C. T., Székely, M., & KULCHITSKY, V. A. (1997) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.1997.273.1.r407 · Cited by 196 · see citing works

Fever induction pathways: evidence from responses to systemic or local cytokine formation

Roth, J., & de Souza, G. E. P. (2001) · Brazilian Journal of Medical and Biological Research · doi:10.1590/s0100-879x2001000300003 · Cited by 194 · see citing works

Vagotomy Blocks the Induction of Interleukin-1β (IL-1β) mRNA in the Brain of Rats in Response to Systemic IL-1β

Hansen, M. K., Taishi, P., Chen, Z., & Krueger, J. M. (1998) · Journal of Neuroscience · doi:10.1523/jneurosci.18-06-02247.1998 · Cited by 193 · see citing works

Role of CD4+ T cells and T-independent mechanisms in acquired resistance to Salmonella typhimurium infection.

Nauciel, C. (1990) · The Journal of Immunology · doi:10.4049/jimmunol.145.4.1265 · Cited by 190 · see citing works

Blockade of lipopolysaccharide-induced fever by subdiaphragmatic vagotomy in guinea pigs

SEHIC, E., & Blatteis, C. M. (1996) · Brain Research · doi:10.1016/0006-8993(96)00326-5 · Cited by 186 · see citing works

T Cell Responses to Gram-Negative Intracellular Bacterial Pathogens: A Role for CD8+ T Cells in Immunity to Salmonella Infection and the Involvement of MHC Class Ib Molecules

Lo, W.-F., Ong, H., Metcalf, E. S., & Soloski, M. J. (1999) · The Journal of Immunology · doi:10.4049/jimmunol.162.9.5398 · Cited by 167 · see citing works

Expression of c-fos in regions of the basal limbic forebrain following intra-cerebroventricular corticotropin-releasing factor in unstressed or stressed male rats

Arnold, F. J. L., de Lucas Bueno, M., Shiers, H., Hancock, D. C., Evan, G. I., & Herbert, J. (1992) · Neuroscience · doi:10.1016/0306-4522(92)90322-s · Cited by 155 · see citing works

Entry and survival of Salmonella typhimurium in dendritic cells and presentation of recombinant antigens do not require macrophage-specific virulence factors

Niedergang, F., Sirard, J., Blanc, C. T., & Kraehenbühl, J.-P. (2000) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.97.26.14650 · Cited by 141 · see citing works

Salmonella invasion of nonphagocytic cells induces formation of macropinosomes in the host cell

del Portillo, F. G., & Finlay, B. B. (1994) · Infection and Immunity · doi:10.1128/iai.62.10.4641-4645.1994 · Cited by 136 · see citing works

The involvement of tumor necrosis factor in immunity to Salmonella infection

Tite, J. P., Dougan, G., & Chatfield, S. N. (1991) · The Journal of Immunology · doi:10.4049/jimmunol.147.9.3161 · Cited by 121 · see citing works

Bacterial Endotoxin Induces Fos Immunoreactivity in Primary Afferent Neurons of the Vagus Nerve

Gaykema, R. P. A., Goehler, L. E., Tilders, F. J. H., Bol, J. G. J. M., McGorry, M. M., Fleshner, M., Maier, S. F., & Watkins, L. R. (1998) · NeuroImmunoModulation · doi:10.1159/000026343 · Cited by 118 · see citing works

Vagotomy attenuates the behavioural but not the pyrogenic effects of interleukin-1 in rats

Luheshi, G. N., Bluthé, R.-M., Rushforth, D. A., MULCAHY, N., Konsman, J. P., Goldbach, M., & Dantzer, R. (2000) · Autonomic Neuroscience · doi:10.1016/s1566-0702(00)00231-9 · Cited by 106 · see citing works

Flagella help Salmonella typhimurium survive within murine macrophages

Weinstein, D. L., Carsiotis, M., Lissner, C. R., & O’Brien, A. D. (1984) · Infection and Immunity · doi:10.1128/iai.46.3.819-825.1984 · Cited by 97 · see citing works

Th1 response in Salmonella typhimurium-infected mice with a high or low rate of bacterial clearance

Pié, S., Truffa‐Bachi, P., Pla, M., & Nauciel, C. (1997) · Infection and Immunity · doi:10.1128/iai.65.11.4509-4514.1997 · Cited by 91 · see citing works

Identification of a natural T cell epitope presented by Salmonella-infected macrophages and recognized by T cells from orally immunized mice

Cookson, B. T., & Bevan, M. J. (1997) · The Journal of Immunology · doi:10.4049/jimmunol.158.9.4310 · Cited by 90 · see citing works

Subdiaphragmatic vagotomy inhibits intra-abdominal interleukin-1β stimulation of adrenocorticotropin secretion

Kapcala, L. P., He, J., Gao, Y., Pieper, J. O., & DeTolla, L. J. (1996) · Brain Research · doi:10.1016/0006-8993(96)00511-2 · Cited by 83 · see citing works

Bacterial Lipopolysaccharide‐Induced Changes in FOS Protein Expression in the Rat Brain: Correlation with Thermoregulatory Changes and Plasma Corticosterone

Hare, A., Clarke, G., & Tolchard, S. (1995) · Journal of Neuroendocrinology · doi:10.1111/j.1365-2826.1995.tb00716.x · Cited by 72 · see citing works

LPS-induced Fos expression in oxytocin and vasopressin neurons of the rat hypothalamus

Matsunaga, W., Miyata, S., Takamata, A., Bun, H., Nakashima, T., & Kiyohara, T. (2000) · Brain Research · doi:10.1016/s0006-8993(99)02418-x · Cited by 70 · see citing works

Thermoregulatory manifestations of systemic inflammation: lessons from vagotomy

Romanovsky, A. A. (2000) · Autonomic Neuroscience · doi:10.1016/s1566-0702(00)00218-6 · Cited by 66 · see citing works

Early response genes as markers of neuronal activity and growth factor action.

Sagar, S. M., & Sharp, F. R. (1993) · PubMed · Cited by 50 · see citing works

Effect of cholecystokinin on cytokines during endotoxic shock in rats

Ling, Y.-L., Meng, A., Zhao, X., Shan, B.-E., Zhang, J., & Zhang, X. (2001) · World Journal of Gastroenterology · doi:10.3748/wjg.v7.i5.667 · Cited by 46 · see citing works

Evidence for Hypothalamic Paraventricular Nucleus as an Integrative Center of Neuroimmunomodulation

Yang, H., Wang, L., & Ju, G. (1998) · NeuroImmunoModulation · doi:10.1159/000097330 · Cited by 38 · see citing works

Effect of nucleus tractus solitarius lesions on fever produced by interleukin-1β

Gordon, F. J. (2000) · Autonomic Neuroscience · doi:10.1016/s1566-0702(00)00228-9 · Cited by 29 · see citing works

Pyrogenic signaling via vagal afferents: what stimulates their receptors?

Blatteis, C. M., & Li, S. (2000) · Autonomic Neuroscience · doi:10.1016/s1566-0702(00)00221-6 · Cited by 26 · see citing works

Does the formation of lipopolysaccharide tolerance require intact vagal innervation of the liver?

Ivanov, A. I., KULCHITSKY, V. A., Sugimoto, N., Simons, C. T., & Romanovsky, A. A. (2000) · Autonomic Neuroscience · doi:10.1016/s1566-0702(00)00229-0 · Cited by 26 · see citing works

[Induction and visualization of c-fos oncogene--a new method reflecting the functional neural pathways].

Zhang, X., & Gao, J. (1991) · PubMed · Cited by 6 · see citing works

[Recent progress in the use of immediate early genes in neuroscience].

Zc, X., & Xh, J. (1997) · PubMed · Cited by 1 · see citing works

Mind-altering microorganisms: the impact of the gut microbiota on brain and behaviour

Cryan, J. F., & Dinan, T. G. (2012) · Nature Reviews Neuroscience · doi:10.1038/nrn3346 · Cited by 4,572 · see citing works

Normal gut microbiota modulates brain development and behavior

Heijtz, R. D., Wang, S., Anuar, F., Qian, Y., Björkholm, B., Samuelsson, A., Hibberd, M. L., Forssberg, H., & Pettersson, S. (2011) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1010529108 · Cited by 3,228 · see citing works

The Role of Short-Chain Fatty Acids From Gut Microbiota in Gut-Brain Communication

Silva, Y. P., Bernardi, A., & Frozza, R. L. (2020) · Frontiers in Endocrinology · doi:10.3389/fendo.2020.00025 · Cited by 3,043 · see citing works

Postnatal microbial colonization programs the hypothalamic–pituitary–adrenal system for stress response in mice

Sudo, N., Chida, Y., Aiba, Y., Sonoda, J., Oyama, N., Yu, X., Kubo, C., & Koga, Y. (2004) · The Journal of Physiology · doi:10.1113/jphysiol.2004.063388 · Cited by 2,735 · see citing works

The Controversial Role of Human Gut Lachnospiraceae

Vacca, M., Celano, G., Calabrese, F. M., Portincasa, P., Gobbetti, M., & De Angelis, M. (2020) · Microorganisms · doi:10.3390/microorganisms8040573 · Cited by 1,688 · see citing works

Microbial reconstitution reverses maternal diet-induced social and synaptic deficits in offspring

Buffington, S. A., Di Prisco, G. V., Auchtung, T. A., Ajami, N. J., Petrosino, J. F., & Costa-Mattioli, M. (2016) · Cell · doi:10.1016/j.cell.2016.06.001 · Cited by 1,163 · see citing works

Microbiota and neurodevelopmental windows: implications for brain disorders

Borre, Y. E., O’Keeffe, G. W., Clarke, G., Stanton, C., Dinan, T. G., & Cryan, J. F. (2014) · Trends in Molecular Medicine · doi:10.1016/j.molmed.2014.05.002 · Cited by 1,089 · see citing works

The microbiome-gut-brain axis: from bowel to behavior

Cryan, J. F., & O’Mahony, S. M. (2011) · Neurogastroenterology & Motility · doi:10.1111/j.1365-2982.2010.01664.x · Cited by 990 · see citing works

Mechanisms underlying microbial-mediated changes in social behavior in mouse models of autism spectrum disorder

Sgritta, M., Dooling, S. W., Buffington, S. A., Momin, E. N., Francis, M. B., Britton, R. A., & Costa-Mattioli, M. (2019) · Neuron · doi:10.1016/j.neuron.2018.11.018 · Cited by 865 · see citing works

The Relationship Between Intestinal Microbiota and the Central Nervous System in Normal Gastrointestinal Function and Disease

Collins, S. M., & Bercik, P. (2009) · Gastroenterology · doi:10.1053/j.gastro.2009.01.075 · Cited by 612 · see citing works

Vagal pathways for microbiome-brain-gut axis communication

Forsythe, P., Bienenstock, J., & Kunze, W. A. (2014) · Advances in Experimental Medicine and Biology · doi:10.1007/978-1-4939-0897-4_5 · Cited by 576 · see citing works

Microbiome–microglia connections via the gut–brain axis

Abdel-Haq, R., Schlachetzki, J. C. M., Glass, C. K., & Mazmanian, S. K. (2019) · Journal of Experimental Medicine · doi:10.1084/jem.20180794 · Cited by 471 · see citing works

Dysbiosis of gut microbiota and microbial metabolites in Parkinson's disease

Sun, M.-F., & Shen, Y.-Q. (2018) · Ageing Research Reviews · doi:10.1016/j.arr.2018.04.004 · Cited by 445 · see citing works

Microbes and mental health: A review

Rieder, R., Wisniewski, P. J., Alderman, B. L., & Campbell, S. C. (2017) · Brain Behavior and Immunity · doi:10.1016/j.bbi.2017.01.016 · Cited by 429 · see citing works

The influence of neuroinflammation in Autism Spectrum Disorder

Matta, S. M., Hill‐Yardin, E. L., & Crack, P. J. (2019) · Brain Behavior and Immunity · doi:10.1016/j.bbi.2019.04.037 · Cited by 414 · see citing works

Activation in vagal afferents and central autonomic pathways: Early responses to intestinal infection with Campylobacter jejuni

Goehler, L. E., Gaykema, R. P. A., Opitz, N., Reddaway, R., Badr, N., & Lyte, M. (2005) · Brain, Behavior, and Immunity · doi:10.1016/j.bbi.2004.09.002 · Cited by 442 · see citing works

The gut-brain axis: the missing link in depression

Evrensel, A., & Ceylan, M. E. (2015) · Clinical Psychopharmacology and Neuroscience · doi:10.9758/cpn.2015.13.3.239 · Cited by 338 · see citing works

The Impact of Microbiota on Brain and Behavior: Mechanisms & Therapeutic Potential

Borre, Y. E., Moloney, R. D., Clarke, G., Dinan, T. G., & Cryan, J. F. (2014) · Advances in Experimental Medicine and Biology · doi:10.1007/978-1-4939-0897-4_17 · Cited by 329 · see citing works

Interoceptive dysfunction: Toward an integrated framework for understanding somatic and affective disturbance in depression

Harshaw, C. (2015) · Psychological Bulletin · doi:10.1037/a0038101 · Cited by 302 · see citing works

Microbiota regulation of the mammalian gut-brain axis

Burokas, A., Moloney, R. D., Dinan, T. G., & Cryan, J. F. (2015) · Advances in applied microbiology · doi:10.1016/bs.aambs.2015.02.001 · Cited by 300 · see citing works

Voices from within: gut microbes and the CNS

Forsythe, P., & Kunze, W. A. (2013) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-012-1028-z · Cited by 336 · see citing works

Vagus Nerve and Underlying Impact on the Gut Microbiota-Brain Axis in Behavior and Neurodegenerative Diseases

Han, Y., Wang, B., Gao, H., He, C., Hua, R., Liang, C., Zhang, S., Wang, Y., Xin, S., & Xu, J. (2022) · Journal of Inflammation Research · doi:10.2147/jir.s384949 · Cited by 265 · see citing works

Microbiome disturbances and autism spectrum disorders

Rosenfeld, C. S. (2015) · Drug Metabolism and Disposition · doi:10.1124/dmd.115.063826 · Cited by 229 · see citing works

The role of the gut microbiota in dietary interventions for depression and anxiety

Bear, T. L. K., Dalziel, J. E., Coad, J., Roy, N. C., Butts, C. A., & Gopal, P. K. (2020) · Advances in Nutrition · doi:10.1093/advances/nmaa016 · Cited by 229 · see citing works

Vagus nerve stimulation in brain diseases: Therapeutic applications and biological mechanisms

Wang, Y., Zhan, G., Cai, Z., Jiao, B., Zhao, Y., Li, S., & Luo, A. (2021) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2021.04.018 · Cited by 207 · see citing works

Immunoexcitotoxicity as a central mechanism in chronic traumatic encephalopathy-A unifying hypothesis

Blaylock, R. L., & Maroon, J. C. (2011) · Surgical Neurology International · doi:10.4103/2152-7806.83391 · Cited by 202 · see citing works

Energy‑dense diet triggers changes in gut microbiota, reorganization of gut‑brain vagal communication and increases body fat accumulation

C. Vaughn, A., M. Cooper, E., M. DiLorenzo, P., J. O’Loughlin, L., E. Konkel, M., H. Peters, J., Hajnal, A., Sen, T., Hye Lee, S., B. de La Serre, C., et al. (2017) · Acta Neurobiologiae Experimentalis · doi:10.21307/ane-2017-033 · Cited by 166 · see citing works

Human-Derived Bifidobacterium dentium Modulates the Mammalian Serotonergic System and Gut–Brain Axis

Engevik, M. A., Luck, B., Visuthranukul, C., Ihekweazu, F. D., Engevik, A. C., Shi, Z., Danhof, H. A., Chang-Graham, A. L., Hall, A., Endres, B. T., et al. (2021) · Cellular and Molecular Gastroenterology and Hepatology · doi:10.1016/j.jcmgh.2020.08.002 · Cited by 164 · see citing works

Bacterial Metabolites of Human Gut Microbiota Correlating with Depression

Averina, O. V., Zorkina, Y., Yunes, R. А., Kovtun, A. S., Ushakova, V. M., Morozova, A. Y., Kostyuk, G. P., Даниленко, В. Н., & Chekhonin, V. P. (2020) · International Journal of Molecular Sciences · doi:10.3390/ijms21239234 · Cited by 166 · see citing works

Microbes and the mind: emerging hallmarks of the gut microbiota-brain axis

Bauer, K. C., Huus, K. E., & Finlay, B. B. (2016) · Cellular Microbiology · doi:10.1111/cmi.12585 · Cited by 151 · see citing works

Intestinal Microbiota as Modulators of the Immune System and Neuroimmune System: Impact on the Host Health and Homeostasis

Maranduba, C. M. D. C., de Castro, S. B. R., de Souza, G. T., Rossato, C., da Guia, F. C., Valente, M. A. S., Rettore, J. V. P., Maranduba, C. P., de Souza, C. M., do Carmo, A. M. R., et al. (2015) · Journal of Immunology Research · doi:10.1155/2015/931574 · Cited by 135 · see citing works

Effects of single and combined toxic exposures on the gut microbiome: Current knowledge and future directions

Tsiaoussis, J., Antoniou, M. N., Koliarakis, I., Mesnage, R., Vardavas, C. I., Izotov, B. N., Psaroulaki, A., & Tsatsakis, A. M. (2019) · Toxicology Letters · doi:10.1016/j.toxlet.2019.04.014 · Cited by 134 · see citing works

Gut microbial communities modulating brain development and function

Al‐Asmakh, M., Anuar, F., Zadjali, F., Rafter, J. J., & Pettersson, S. (2012) · Gut Microbes · doi:10.4161/gmic.21287 · Cited by 117 · see citing works

Coprophagy prevention alters microbiome, metabolism, neurochemistry, and cognitive behavior in a small mammal

Bo, T., Zhang, X., Kohl, K. D., Wen, J., Tian, S.-J., & Wang, D. (2020) · The ISME Journal · doi:10.1038/s41396-020-0711-6 · Cited by 115 · see citing works

Sensory neuron regulation of gastrointestinal inflammation and bacterial host defence

Lai, N. Y., Mills, K. R., & Chiu, I. M. (2017) · Journal of Internal Medicine · doi:10.1111/joim.12591 · Cited by 113 · see citing works

Ghrelin

Wu, J. T., & Kral, J. G. (2004) · Annals of Surgery · doi:10.1097/01.sla.0000118561.54919.61 · Cited by 111 · see citing works

The gut-brain relationship: investigating the effect of multispecies probiotics on anxiety in a randomized placebo-controlled trial of healthy young adults

Tran, N., Zhebrak, M., Yacoub, C., Pelletier, J., & Hawley, D. (2019) · Journal of Affective Disorders · doi:10.1016/j.jad.2019.04.043 · Cited by 104 · see citing works

Loss of vagal anti-inflammatory effect: in vivo visualization and adoptive transfer

O’Mahony, C., van der Kleij, H. P. M., Bienenstock, J., Shanahan, F., & O’Mahony, L. (2009) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.90904.2008 · Cited by 102 · see citing works

The microbiota–microglia axis in central nervous system disorders

Mossad, O., & Erny, D. (2020) · Brain Pathology · doi:10.1111/bpa.12908 · Cited by 98 · see citing works

The microbiota influences cell death and microglial colonization in the perinatal mouse brain

Castillo-Ruiz, A., Mosley, M., George, A. J., Mussaji, L. F., Fullerton, E. F., Ruszkowski, E. M., Jacobs, A. J., Gewirtz, A. T., Chassaing, B., & Forger, N. G. (2018) · Brain, Behavior, and Immunity · doi:10.1016/j.bbi.2017.08.027 · Cited by 91 · see citing works

Targeting the gut microbiota to influence brain development and function in early life

Wang, S., Harvey, L., Martı́n, R., van der Beek, E. M., Knol, J., Cryan, J. F., & Renes, I. B. (2018) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2018.09.002 · Cited by 92 · see citing works

The contribution of the peripheral immune system to neurodegeneration

Berriat, F., Lobsiger, C. S., & Boillée, S. (2023) · Nature Neuroscience · doi:10.1038/s41593-023-01323-6 · Cited by 87 · see citing works

Ghrelin and cancer progression

Lin, T., & Hsiao, M. (2017) · Biochimica et Biophysica Acta (BBA) - Reviews on Cancer · doi:10.1016/j.bbcan.2017.02.002 · Cited by 90 · see citing works

Man and the Microbiome: A New Theory of Everything?

Butler, M., Cryan, J. F., & Dinan, T. G. (2019) · Annual Review of Clinical Psychology · doi:10.1146/annurev-clinpsy-050718-095432 · Cited by 91 · see citing works

Helminth therapy and multiple sclerosis

Fleming, J. O. (2013) · International Journal for Parasitology · doi:10.1016/j.ijpara.2012.10.025 · Cited by 83 · see citing works

The gut microbiota in neuropsychiatric disorders

Grochowska, M., Wojnar, M., & Radkowski, M. (2018) · Acta Neurobiologiae Experimentalis · doi:10.21307/ane-2018-008 · Cited by 73 · see citing works

Strong Expression of Interleukin-1 Receptor Type I in the Rat Carotid Body

Wang, X., Wang, B., Duan, X.-L., Zhang, P., Ding, Y., Jia, Y., Jiao, X., & Ju, G. (2002) · Journal of Histochemistry & Cytochemistry · doi:10.1177/002215540205001213 · Cited by 70 · see citing works

Neurotransmitter Profiles Are Altered in the Gut and Brain of Mice Mono-Associated with Bifidobacterium dentium

Luk, B., Horvath, T. D., Engevik, K. A., Ruan, W. H., Haidacher, S. J., Hoch, K. M., Oezguen, N., Spinler, J. K., Haag, A. M., Versalovic, J. A., et al. (2021) · Biomolecules · doi:10.3390/biom11081091 · Cited by 67 · see citing works

Vagotomy and insights into the microbiota-gut-brain axis

Liu, Y., & Forsythe, P. (2021) · Neuroscience Research · doi:10.1016/j.neures.2021.04.001 · Cited by 67 · see citing works

Inflammatory Cytokines and Antipsychotic-Induced Weight Gain: Review and Clinical Implications

Fonseka, T. M., Müller, D. J., & Kennedy, S. H. (2016) · Complex Psychiatry · doi:10.1159/000441521 · Cited by 64 · see citing works

Gut microbiota and neuropsychiatric disorders: Implications for neuroendocrine-immune regulation

Ge, T., Yao, X., Zhao, H., Yang, W., Zou, X., Peng, F., Li, B., & Cui, R. (2021) · Pharmacological Research · doi:10.1016/j.phrs.2021.105909 · Cited by 62 · see citing works

Dysbiotic drift and biopsychosocial medicine: how the microbiome links personal, public and planetary health

Prescott, S. L., Wegienka, G., Logan, A. C., & Katz, D. L. (2018) · BioPsychoSocial Medicine · doi:10.1186/s13030-018-0126-z · Cited by 53 · see citing works

Alleviating effect of vagus nerve cutting in Salmonella-induced gut infections and anxiety-like behavior via enhancing microbiota-derived GABA

Zou, Q., Han, S., Liang, J., Yan, G., Wang, Q., Wang, Y., Zhang, Z., Hu, J., Li, J., Tian, Y., et al. (2024) · Brain Behavior and Immunity · doi:10.1016/j.bbi.2024.04.034 · Cited by 53 · see citing works

The Microbiome and Mental Health: Looking Back, Moving Forward with Lessons from Allergic Diseases

Logan, A. C., Jacka, F. N., Craig, J. M., & Prescott, S. L. (2016) · Clinical Psychopharmacology and Neuroscience · doi:10.9758/cpn.2016.14.2.131 · Cited by 51 · see citing works

The microbiome and cognitive aging: a review of mechanisms

Komanduri, M., Gondalia, S. V., Scholey, A. B., & Stough, C. K. K. (2019) · Psychopharmacology · doi:10.1007/s00213-019-05231-1 · Cited by 48 · see citing works

Gut-to-Brain Axis in Autism Spectrum Disorders

Kraneveld, A. D., Szklany, K., de Theije, C. G. M., & Garssen, J. (2016) · International review of neurobiology · doi:10.1016/bs.irn.2016.09.001 · Cited by 47 · see citing works

Attribution of Ghrelin to Cancer; Attempts to Unravel an Apparent Controversy

Soleymanjahi, S., Sadeghi, F., Khoshbin, A. P., Khani, L., Roosta, V., & Zendehdel, K. (2019) · Frontiers in Oncology · doi:10.3389/fonc.2019.01014 · Cited by 41 · see citing works

Experimental gastritis leads to anxiety- and depression-like behaviors in female but not male rats

Luo, J., Wang, T., Liang, S., Hu, X., Li, W., & Jin, F. (2013) · Behavioral and Brain Functions · doi:10.1186/1744-9081-9-46 · Cited by 41 · see citing works

Catecholamines and acetylcholine are key regulators of the interaction between microbes and the immune system

Islas-Weinstein, L., Revuelta, A., & Hernández‐Pando, R. (2015) · Annals of the New York Academy of Sciences · doi:10.1111/nyas.12792 · Cited by 38 · see citing works

Reticulate Evolution

Gontier, N. (2015) · Interdisciplinary evolution research · doi:10.1007/978-3-319-16345-1 · Cited by 39 · see citing works

Can microbiology affect psychiatry? A link between gut microbiota and psychiatric disorders

Gulas, E., Wysiadecki, G., Strzelecki, D., Gawlik-Kotelnicka, O., & Polguj, M. (2018) · Psychiatria Polska · doi:10.12740/pp/onlinefirst/81103 · Cited by 38 · see citing works

Vagal sensory pathway for the gut-brain communication

Cao, Y., Li, R., & Bai, L. (2023) · Seminars in Cell and Developmental Biology · doi:10.1016/j.semcdb.2023.07.009 · Cited by 36 · see citing works

Fos Expression in the Rat Brain After Intraperitoneal Injection of Staphylococcus Enterotoxin B and the Effect of Vagotomy

Wang, X., Wang, B., Zhang, X., Duan, X., Guo, X., & Ju, G. (2004) · Neurochemical Research · doi:10.1023/b:nere.0000035801.81825.2a · Cited by 33 · see citing works

Living Therapeutics: The Next Frontier of Precision Medicine

Kelly, V. W., Liang, B. K., & Sirk, S. J. (2020) · ACS Synthetic Biology · doi:10.1021/acssynbio.0c00444 · Cited by 30 · see citing works

Fos expression in tyrosine hydroxylase-containing neurons in rat brainstem after visceral noxious stimulation: an immunohistochemical study

Han, F. (2003) · World Journal of Gastroenterology · doi:10.3748/wjg.v9.i5.1045 · Cited by 31 · see citing works

Capsaicin-sensitive vagal afferent neurons contribute to the detection of pathogenic bacterial colonization in the gut

Riley, T. P., Neal‐McKinney, J. M., Buelow, D. R., Konkel, M. E., & Simasko, S. M. (2013) · Journal of Neuroimmunology · doi:10.1016/j.jneuroim.2013.01.009 · Cited by 31 · see citing works

Levels of vasoactive intestinal peptide, cholecystokinin and calcitonin gene-related peptide in plasma and jejunum of rats following traumatic brain injury and underlying significance in gastrointestinal dysfunction

Hang, C., Shi, J., Li, J., Wu, W., Li, W., & Yin, H.-X. (2004) · World Journal of Gastroenterology · doi:10.3748/wjg.v10.i6.875 · Cited by 31 · see citing works

Acupuncture influences multiple diseases by regulating gut microbiota

Xu, H., Luo, Y., Li, Q., & Zhu, H. (2024) · Frontiers in Cellular and Infection Microbiology · doi:10.3389/fcimb.2024.1371543 · Cited by 31 · see citing works

Advantages and limitations of experimental autoimmune encephalomyelitis in breaking down the role of the gut microbiome in multiple sclerosis

Melamed, E., Palmer, J. L., & Fonken, C. (2022) · Frontiers in Molecular Neuroscience · doi:10.3389/fnmol.2022.1019877 · Cited by 27 · see citing works

Human leukemia antigen-A*0201-restricted epitopes of human endogenous retrovirus W family envelope (HERV-W env) induce strong cytotoxic T lymphocyte responses

Tu, X., Li, S., Zhao, L., Xiao, R., Wang, X., & Zhu, F. (2017) · Virologica Sinica · doi:10.1007/s12250-017-3984-9 · Cited by 28 · see citing works

Japanese quail (Coturnix japonica) as a novel model to study the relationship between the avian microbiome and microbial endocrinology-based host-microbe interactions

Lyte, J. M., Keane, J., Eckenberger, J., Anthony, N. B., Shrestha, S., Marasini, D., Daniels, K. M., Caputi, V., Donoghue, A. M., & Lyte, M. (2021) · Microbiome · doi:10.1186/s40168-020-00962-2 · Cited by 26 · see citing works

Neural–endocrine–immune complex in the central modulation of tumorigenesis: Facts, assumptions, and hypotheses

Mravec, B., Gidron, Y., Kukanova, B., Bízik, J., Kiss, A., & Hulín, I. (2006) · Journal of Neuroimmunology · doi:10.1016/j.jneuroim.2006.07.003 · Cited by 26 · see citing works

Stress and the Gut-Brain Axis: Implications for Cancer, Inflammation and Sepsis

Moughnyeh, M., Brawner, K. M., Kennedy, B. A., Yeramilli, V. A., Udayakumar, N., Graham, J. A., & Martin, C. A. (2021) · Journal of Surgical Research · doi:10.1016/j.jss.2021.02.055 · Cited by 22 · see citing works

Nutritional Criminology: Why the Emerging Research on Ultra-Processed Food Matters to Health and Justice

Prescott, S. L., Logan, A. C., D’Adamo, C. R., Holton, K. F., Lowry, C. A., Marks, J., Moodie, R., & Poland, B. D. (2024) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph21020120 · Cited by 26 · see citing works

Symbiosis—Evolution’s Co-Author

Zook, D. P. (2015) · Interdisciplinary evolution research · doi:10.1007/978-3-319-16345-1_2 · Cited by 23 · see citing works

Brain changes detected by functional magnetic resonance imaging and spectroscopy in patients with Crohn's disease

Lv, K., Fan, Y., Xu, L., & Xu, M. (2017) · World Journal of Gastroenterology · doi:10.3748/wjg.v23.i20.3607 · Cited by 21 · see citing works

Microbial Reprogramming in Obsessive–Compulsive Disorders: A Review of Gut–Brain Communication and Emerging Evidence

Bendriss, G., MacDonald, R. S., & McVeigh, C. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms241511978 · Cited by 25 · see citing works

Ultrastructure of junction areas between neurons and astrocytes in rat supraoptic nuclei

Duan, L., Yuan, H. M., Su, C., Liu, Y., & Rao, Z. (2004) · World Journal of Gastroenterology · doi:10.3748/wjg.v10.i1.117 · Cited by 18 · see citing works

Air pollution accelerates the development of obesity and Alzheimer’s disease: the role of leptin and inflammation - a mini-review

Campolim, C. M., Schimenes, B. C., Veras, M. M., Kim, Y., & Prada, P. O. (2024) · Frontiers in Immunology · doi:10.3389/fimmu.2024.1401800 · Cited by 19 · see citing works

Helminth Therapy for MS

Tănăsescu, R., & Constantinescu, C. S. (2014) · Current topics in behavioral neurosciences · doi:10.1007/7854_2014_361 · Cited by 17 · see citing works

Acetylcholine regulates the development of experimental autoimmune encephalomyelitis via the CD4+ cells proliferation and differentiation

Zhou, L., Lin, X., Ma, X., Liu, Y., Ma, L., Chen, Z., Chen, H., Si, L., & Chen, X. (2020) · International Journal of Neuroscience · doi:10.1080/00207454.2019.1706504 · Cited by 16 · see citing works

Salmonella Strain Specificity Determines Post-typhoid Central Nervous System Complications: Intervention by Lactiplantibacillus plantarum at Gut-Brain Axis

Kaur, A., Chopra, K., Kaur, I. P., & Rishi, P. (2020) · Frontiers in Microbiology · doi:10.3389/fmicb.2020.01568 · Cited by 16 · see citing works

Reciprocal gut–brain evolutionary symbiosis provokes and amplifies the postinjury systemic inflammatory response syndrome

Lyte, M. (2009) · Surgery · doi:10.1016/j.surg.2009.06.002 · Cited by 16 · see citing works

Effects of Three Distinct 2-Week Long Diet Strategies After Transport on Weaned Pigs' Short and Long-Term Welfare Markers, Behaviors, and Microbiota

Parois, S. P., Duttlinger, A. W., Richert, B. T., Lindemann, S. R., Johnson, J. S., & Marchant, J. N. (2020) · Frontiers in Veterinary Science · doi:10.3389/fvets.2020.00140 · Cited by 15 · see citing works

Potential improvements of the cognition of piglets through a synbiotic supplementation from 1 to 28 days via the gut microbiota

Parois, S. P., Eicher, S. D., Lindemann, S. R., & Marchant, J. N. (2021) · Scientific Reports · doi:10.1038/s41598-021-03565-5 · Cited by 15 · see citing works

Crime and Nourishment: A Narrative Review Examining Ultra-Processed Foods, Brain, and Behavior

Prescott, S. L., Logan, A. C., LaFata, E. M., Naik, A., Nelson, D. H., Robinson, M. B., & Soble, L. (2024) · Dietetics · doi:10.3390/dietetics3030025 · Cited by 14 · see citing works

Significance of vagus nerve function in terms of pathogenesis of psychosocial disorders

Kakinuma, Y. (2020) · Neurochemistry International · doi:10.1016/j.neuint.2020.104934 · Cited by 14 · see citing works

Multiple sclerosis and the microbiota

Engelenburg, H. J., Lucassen, P. J., Sarafian, J. T., Parker, W., & Laman, J. D. (2022) · Evolution Medicine and Public Health · doi:10.1093/emph/eoac009 · Cited by 13 · see citing works

Disruption of the lung-gut-brain axis is responsible for cortex damage induced by pulmonary exposure to zinc oxide nanoparticles

Zhang, L., Zhang, Y., Jiang, X., Mao, L., Xia, Y., Fan, Y., Li, N., Jiang, Z., Qin, X., Jiang, Y., et al. (2022) · Toxicology · doi:10.1016/j.tox.2022.153390 · Cited by 13 · see citing works

The Role of the Microbiome in the Relationship of Asthma and Affective Disorders

Trueba, A. F., Ritz, T., & Trueba, G. A. (2016) · Advances in experimental medicine and biology · doi:10.1007/978-3-319-20215-0_13 · Cited by 13 · see citing works

Unravelling the potential of gut microbiota in sustaining brain health and their current prospective towards development of neurotherapeutics

Banerjee, A., Pradhan, L. K., Sahoo, P. K., Jena, K. K., Chauhan, N. R., Chauhan, S., & Das, S. K. (2021) · Archives of Microbiology · doi:10.1007/s00203-021-02276-9 · Cited by 13 · see citing works

Cytokines in Neural Signaling to the Brain

Goehler, L. (2008) · Neuroimmune biology · doi:10.1016/s1567-7443(07)10016-8 · Cited by 12 · see citing works

Effects of common plastic products heat exposure on cognition: Mediated by gut microbiota

Hu, N., Pan, D., Yang, Y. H., Pu, L., He, X., Wang, H., Zhang, X., Du, Y., Yu, Z., He, S., et al. (2023) · Ecotoxicology and Environmental Safety · doi:10.1016/j.ecoenv.2023.114758 · Cited by 11 · see citing works

Gut microbiota in Parkinson’s disease patients: hospital-based study

Khedr, E. M., Ali, A. M., Daef, E., Hassan, H. M., Alaa, A., & Gamea, A. (2021) · The Egyptian Journal of Neurology Psychiatry and Neurosurgery · doi:10.1186/s41983-021-00407-z · Cited by 11 · see citing works

Modulation of amoebic hepatic abscess by the parasympathetic system

Muñoz‐Ortega, M. H., Quintanar‐Stephano, A., Lorenzana, M. G., CAMPOS‐ESPARZA, M. R., Silva-Briano, M., Adabache-Ortíz, A., Campos-Rodrı́guez, R., Rodríguez, M. G., & Ventura‐Juárez, J. (2010) · Parasite Immunology · doi:10.1111/j.1365-3024.2010.01245.x · Cited by 10 · see citing works

Gut microbiota analysis and its significance in vasovagal syncope in children

Bai, W., Chen, S. Y., Tang, C., Qi, J., Cui, Q., Xu, M., Du, J., & Jin, H. (2019) · Chinese Medical Journal · doi:10.1097/cm9.0000000000000086 · Cited by 10 · see citing works

Vagus nerve stimulation (VNS) preventing postoperative cognitive dysfunction (POCD): two potential mechanisms in cognitive function

Xie, Z.-F., Wang, S., Gao, Y., Zhang, Y.-D., Han, Y., Huang, J., Gao, M.-N., & Wang, C.-G. (2024) · Molecular and Cellular Biochemistry · doi:10.1007/s11010-024-05091-0 · Cited by 9 · see citing works

The Human Microbiome—A Physiologic Perspective

Yang, X. J., Louwies, T., Mars, R. A. T., & Kashyap, P. (2024) · Comprehensive physiology · doi:10.1002/j.2040-4603.2024.tb00299.x · Cited by 9 · see citing works

The Oral Microbiota: Implications in Mucosal Health and Systemic Disease—Crosstalk with Gut and Brain

Miranda, V., Laarej, K., & Cavaliere, C. (2026) · Cells · doi:10.3390/cells15010082 · Cited by 10 · see citing works

Gut microbiota sPARk vagus nerve excitation

Singh, A., Serre, C. B. D. L., & de Lartigue, G. (2020) · The Journal of Physiology · doi:10.1113/jp279763 · Cited by 9 · see citing works

The influence of vagotomy on Fos expression in PVN and SON induced by Salmonella Typhimurine infection of gastrointestinal tract in the rat

Ju, G. (2001) · Zhongguo shenjing kexue zazhi

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Wang, X., Wang, B.-R., Zhang, X.-J., Xu, Z., Ding, Y.-Q., Ju, G., Wang, X., Wang, B.-R., Xu, Z., Ding, Y.-Q., et al. (2015)

Fos Expression in the Rat Brain After Intraperitoneal Injection of Staphylococcus Enterotoxin B and the Effect of Vagotomy

Wang, X., Wang, B., Zhang, X., Duan, X., Guo, X., & Ju, G. (2004) · Neurochemical Research · doi:10.1023/b:nere.0000035801.81825.2a · Cited by 33 · see citing works

Bacterial Endotoxin Induces Fos Immunoreactivity in Primary Afferent Neurons of the Vagus Nerve

Gaykema, R. P. A., Goehler, L. E., Tilders, F. J. H., Bol, J. G. J. M., McGorry, M. M., Fleshner, M., Maier, S. F., & Watkins, L. R. (1998) · NeuroImmunoModulation · doi:10.1159/000026343 · Cited by 118 · see citing works

Loss of vagal integrity disrupts immune components of the microbiota-gut-brain axis and inhibits the effect of Lactobacillus rhamnosus on behavior and the corticosterone stress response

Liu, Y., Sanderson, D., Mian, M. F., Neufeld, K. M., & Forsythe, P. (2021) · Neuropharmacology · doi:10.1016/j.neuropharm.2021.108682 · Cited by 87 · see citing works