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Cited by 328

The DOI matches its Crossref record; 4 of the 4 references it cites were found in a registry or an index.

GABA-containing neurons in the ventral tegmental area project to the nucleus accumbens in rat brain

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Van Bockstaele, E.J., Pickel, V.M.·1995·Brain Research
DOI 10.1016/0006-8993(95)00334-m
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Abstract

The ventral tegmental area receives a gamma-aminobutyric acid (GABA) innervation from the nucleus accumbens and contains GABA immunoreactive neurons believed to be interneurons. We combined the immunocytochemical detection of retrogradely transported Fluoro-Gold (FG) from the nucleus accumbens (Acb) with the detection of GABA within the same section of tissue in the ventral tegmental area (VTA) of the rat brain to determine whether there might also be reciprocal GABAergic projections in the mesolimbic pathway. Immunoperoxidase labeling for FG and immunogold-silver labeling for GABA were most readily distinguished within perikarya and dendrites in sections examined by electron microscopy. Ultrastructural observations indicated that 36% (n = 110) of the FG-labeled perikarya and dendrites also contained GABA immunoreactivity. The present results provide the first evidence that GABA is contained in a subpopulation of neurons in the mesolimbic pathway from the VTA to the Acb. The reciprocity of this circuitry may provide an important feedback loop thus facilitating inhibition of motor activity.

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Show all 4 references

Research works printed but not linked: 25

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Metadata

Authors
Van Bockstaele, E. J., & Pickel, V. M.
Venue
Brain Research
Publisher
Elsevier BV
Published
1995-06
Volume
682
Issue
1-2
Pages
215-221
ISSN
0006-8993 (ISSN-L)
DOI
10.1016/0006-8993(95)00334-m
OpenAlex
W2023190048
Cited by
328
References
4
FWCI
1.52
Type
journal article
Language
en
Open access
hybrid
Licence

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CoChat. (2026). Citation check: GABA-containing neurons in the ventral tegmental area project to the nucleus accumbens in rat brain. https://app.cochat.ai/papers/10.1016/0006-8993(95)00334-m
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Van Bockstaele, E. J., & Pickel, V. M. (1995). GABA-containing neurons in the ventral tegmental area project to the nucleus accumbens in rat brain. Brain Research. https://doi.org/10.1016/0006-8993(95)00334-m

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