Bone creep-fatigue damage accumulation
Open accessAbstract
Creep and fatigue tests were performed on human femoral cortical bone and the results were compared to a cumulative damage model for bone fracture. Fatigue tests in tension, compression, and reversed loading with a tensile mean stress were conducted at 2 Hz and 0.02 Hz. Load frequency had a strong influence on the number of cycles to failure but did not influence the total time to failure. Bone displayed poor creep-fracture properties in both tension and compression. The fracture surfaces of the tensile creep specimens are distinctly different than those of the compressive specimens. The results suggest that tensile cyclic loading creates primarily time-dependent damage and compressive cyclic loading creates primarily cycle-dependent damage. However, data for load histories involving both tensile and compressive loading indicate lower time to failure than predicted by a simple summation of time-dependent and cycle-dependent damage.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
Cortical bone has greater resistance to fatigue failure at higher loading frequencies.
“Cortical bone has greater resistance to fatigue failure in compression than in tension (22) and at higher loading frequencies (23, 24).”
From Bone Mechanical Properties in Healthy and Diseased States (2018) · cites this paper as [24]
Cites
Miner, M. A. (1945) · Journal of Applied Mechanics · doi:10.1115/1.4009458 · Cited by 6,415 · see citing works
Rupture Time Under Creep Conditions
Kachanov, L. M. (1999) · International Journal of Fracture · doi:10.1023/a:1018671022008 · Cited by 646 · see citing works
Rubin, C. T., & Lanyon, L. E. (1982) · Journal of Experimental Biology · doi:10.1242/jeb.101.1.187 · Cited by 496 · see citing works
A cumulative damage model for bone fracture
Carter, D. R. P., & Caler, W. E. (1985) · Journal of Orthopaedic Research® · doi:10.1002/jor.1100030110 · Cited by 260 · see citing works
Self-citationCarter, D. R. P., & Hayes, W. C. (1977) · Clinical Orthopaedics and Related Research · doi:10.1097/00003086-197709000-00039 · Cited by 258 · see citing works
Self-citationThe Necking and the Rupture of Rods Subjected to Constant Tensile Loads
Hoff, N. J. (1953) · Journal of Applied Mechanics · doi:10.1115/1.4010601 · Cited by 196 · see citing works
Piekarski, K. (1970) · Journal of Applied Physics · doi:10.1063/1.1658323 · Cited by 188 · see citing works
Cosserat micromechanics of human bone: Strain redistribution by a hydration sensitive constituent
Park, H. C., & Lakes, R. S. (1986) · Journal of Biomechanics · doi:10.1016/0021-9290(86)90015-1 · Cited by 181 · see citing works
Viscoelastic properties of wet cortical bone—I. Torsional and biaxial studies
Lakes, R. S., Katz, J. L., & Sternstein, S. S. (1979) · Journal of Biomechanics · doi:10.1016/0021-9290(79)90016-2 · Cited by 180 · see citing works
Cycle-Dependent and Time-Dependent Bone Fracture With Repeated Loading
Carter, D. R., & Caler, W. E. (1983) · Journal of Biomechanical Engineering · doi:10.1115/1.3138401 · Cited by 149 · see citing works
Self-citationLakes, R. S., & Saha, S. (1979) · Science · doi:10.1126/science.432653 · Cited by 125 · see citing works
Dynamic response of biological materials.
Byars, E. F., & McElhaney, J. H. (1965) · NASA Technical Reports Server (NASA) · Cited by 79 · see citing works
Anelasticity in Bone and Echinoderm Skeletons
Currey, J. D. (1965) · Journal of Experimental Biology · doi:10.1242/jeb.43.2.279 · Cited by 73 · see citing works
Work to fracture of canine femoral bone
Moyle, D. D., Welborn, J. W., & Cooke, F. W. (1978) · Journal of Biomechanics · doi:10.1016/0021-9290(78)90055-6 · Cited by 57 · see citing works
Currey, J. D., & Brear, K. (1974) · Calcified Tissue International · doi:10.1007/bf02059054 · Cited by 53 · see citing works
A fractographic study of human long bone
Corondan, G., & Haworth, W. L. (1986) · Journal of Biomechanics · doi:10.1016/0021-9290(86)90153-3 · Cited by 52 · see citing works
Long-Term Torsional Creep in Compact Bone
Lakes, R. S., & Saha, S. (1980) · Journal of Biomechanical Engineering · doi:10.1115/1.3138219 · Cited by 16 · see citing works
Flagged first, then by citations
Cited by
Sorted by citations
Basic biomechanical measurements of bone: A tutorial
Turner, C. H., & Burr, D. B. (1993) · Bone · doi:10.1016/8756-3282(93)90081-k · Cited by 1,666 · see citing works
Bone Mechanical Properties in Healthy and Diseased States
Morgan, E. F., Unnikrisnan, G. U., & Hussein, A. I. (2018) · Annual Review of Biomedical Engineering · doi:10.1146/annurev-bioeng-062117-121139 · Cited by 1,026 · see citing works
“Cortical bone has greater resistance to fatigue failure in compression than in tension (22) and at higher loading frequencies (23, 24).”
The aging of Wolff’s “law”: Ontogeny and responses to mechanical loading in cortical bone
Pearson, O. M., & Lieberman, D. E. (2004) · American Journal of Physical Anthropology · doi:10.1002/ajpa.20155 · Cited by 745 · see citing works
Cyclic mechanical property degradation during fatigue loading of cortical bone
Pattin, C. A., Caler, W. E., & Carter, D. R. (1996) · Journal of Biomechanics · doi:10.1016/0021-9290(94)00156-1 · Cited by 442 · see citing works
Self-citationDoes microdamage accumulation affect the mechanical properties of bone?
Burr, D. B., Turner, C. H., Naick, P., Forwood, M. R., Ambrosius, W., Sayeed Hasan, M., & Pidaparti, R. (1998) · Journal of Biomechanics · doi:10.1016/s0021-9290(98)00016-5 · Cited by 417 · see citing works
Age-related differences in post-yield damage in human cortical bone. Experiment and model
Courtney, A. C., Hayes, W. C., & Gibson, L. J. (1996) · Journal of Biomechanics · doi:10.1016/0021-9290(96)84542-8 · Cited by 131 · see citing works
Compressive fatigue behavior of human vertebral trabecular bone
Rapillard, L., Charlebois, M., & Zysset, P. K. (2006) · Journal of Biomechanics · doi:10.1016/j.jbiomech.2005.04.033 · Cited by 113 · see citing works
Compressive creep behavior of bovine trabecular bone
Bowman, S. M., Keaveny, T. M., Gibson, L. J., Hayes, W. C., & McMahon, T. A. (1994) · Journal of Biomechanics · doi:10.1016/0021-9290(94)90006-x · Cited by 88 · see citing works
Tensile Fatigue in Bone: Are Cycles-, or Time to Failure, or Both, Important?
ZIOUPOS, P., CURREY, J. D., & CASINOS, A. (2001) · Journal of Theoretical Biology · doi:10.1006/jtbi.2001.2316 · Cited by 81 · see citing works
The role of the lamellar interface during torsional yielding of human cortical bone
Jepsen, K. J., Davy, D. T., & Krzypow, D. J. (1999) · Journal of Biomechanics · doi:10.1016/s0021-9290(98)00179-1 · Cited by 81 · see citing works
Yamamoto, E., Paul Crawford, R., Chan, D. D., & Keaveny, T. M. (2006) · Journal of Biomechanics · doi:10.1016/j.jbiomech.2005.05.017 · Cited by 72 · see citing works
A Damage Model for Nonlinear Tensile Behavior of Cortical Bone
Fondrk, M. T., Bahniuk, E. H., & Davy, D. T. (1999) · Journal of Biomechanical Engineering · doi:10.1115/1.2835084 · Cited by 70 · see citing works
- Authors
- Caler, W. E., & Carter, D. R.
- Affiliations
- Stanford University (US)
- United States Department of Veterans Affairs (US)
- Venue
- Journal of Biomechanics
- Publisher
- Elsevier BV
- Published
- 1989
- Volume
- 22
- Issue
- 6-7
- Pages
- 625-635
- ISSN
- 0021-9290 (ISSN-L)
- OpenAlex
- W1998461406
- Cited by
- 263
- References
- 17
- Citations by year
- 2026: 2 · 2025: 6 · 2024: 2 · 2023: 1 · 2022: 5 · 2021: 9 · 2020: 16 · 2019: 7 · 2018: 11 · 2017: 4 · 2016: 5 · 2015: 7 · 2014: 5 · 2013: 11 · 2012: 5
- FWCI
- 2.86
- Type
- journal article
- Language
- en
- Open access
- hybrid
- doi.org
- Licence
- Locations
- Journal of Biomechanics (publishedVersion, cc-by-nc-nd)
- PubMed (publishedVersion)
- Funders
- National Institute of Arthritis and Musculoskeletal and Skin Diseases (AR 32377)
- Topics
- Physical Sciences › Engineering › Mechanics of Materials › Fatigue and fracture mechanics
- Health Sciences › Medicine › Epidemiology › Bone fractures and treatments
- Health Sciences › Medicine › Orthopedics and Sports Medicine › Bone health and osteoporosis research
- Keywords
- fatigue damage, cumulative damage model, femoral cortical bone, load frequency, reversed loading, fracture morphology, time to failure, bone fractures
- MeSH terms
- Adult, Bone and Bones, Elasticity, Haversian System, Humans, Male, Microscopy, Electron, Scanning, Middle Aged, Models, Biological, Stress, Mechanical, Tensile Strength, Time Factors, Fractures, Stress
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
